Abstract:
BACKGROUND:Psoriasis presents many management complexities. A cornerstone of therapy has been topical corticosteroids, although over the past 10 years there have been many additions to the medication armamentarium. Furthermore, various combination regimens and approaches have been advocated. OBJECTIVE:We sought to characterize various patterns of psoriasis health care delivery and the changes associated with these patterns from 1990 to 2001. METHODS:Visits for psoriasis were identified using National Ambulatory Medical Care survey data, a representative survey of visits to physician offices in the United States. We determined basic demographic characteristics, specialty of the physician provider and medications listed at these visits over the 1990-2001 interval. RESULTS:There were more than 13.5 million visits for psoriasis during the 12-year study period. Dermatologists were responsible for the majority of the visits over the study interval (82%) although there was an overall decline in the proportion of psoriasis visits to dermatologists. As a category, the most common medications used for psoriasis were topical steroids. Topical calcipotriene was the single-most listed medication. There was no observed use of non-corticosteroid topical agents at visits to non-dermatologists. Non-dermatologists were as likely as dermatologists to list a systemic medication at a visit as well as use a systemic as monotherapy. DISCUSSION:In conclusion, the primary topical therapies for psoriasis remain clobetasol and calcipotriene. The decreasing role of dermatologists in the treatment of psoriasis is probably a complex issue, but may relate in part to the difficulty of obtaining access to dermatology care.
journal_name
Int J Dermatoljournal_title
International journal of dermatologyauthors
Pearce DJ,Stealey KH,Balkrishnan R,Fleischer AB Jr,Feldman SRdoi
10.1111/j.1365-4632.2006.02532.xsubject
Has Abstractpub_date
2006-04-01 00:00:00pages
370-4issue
4eissn
0011-9059issn
1365-4632pii
IJD2532journal_volume
45pub_type
杂志文章abstract:BACKGROUND:Pemphigus is a group of vesiculobullous disorders in which the blisters usually heal with hyper or hypopigmentation. The appearance of acanthomata at sites of previous blisters has been noted in some cases. METHODS:All cases of pemphigus admitted to the Madras Medical College hospitals during a 2-year perio...
journal_title:International journal of dermatology
pub_type: 杂志文章
doi:10.1046/j.1365-4362.1997.00092.x
更新日期:1997-03-01 00:00:00
abstract:BACKGROUND:There is little research available that describes the natural progression of split-thickness skin graft (STSG) donor site wounds after re-epithelialization. The purpose of this study was to evaluate the longitudinal clinical progress of transepidermal water loss (TEWL), color, and sensory elements in STSG do...
journal_title:International journal of dermatology
pub_type: 杂志文章
doi:10.1111/ijd.14389
更新日期:2019-05-01 00:00:00
abstract:BACKGROUND:Pediculosis capitis is an endemic parasitosis affecting many countries of the world. The aim of this study was to investigate the incidence of head lice infestation in Mersin, Turkey. METHODS:A total of 5318 elementary schoolchildren, aged 8-16 years, were examined for the presence of Pediculus capitis. If ...
journal_title:International journal of dermatology
pub_type: 杂志文章
doi:10.1046/j.1365-4362.2003.01836.x
更新日期:2003-09-01 00:00:00
abstract::A 58-year-old woman with progressive systemic sclerosis developed a butterfly erythematous eruption, hemorrhagic maculae, crusting, and erosions on the face 15 days following administration of D-penicillamine. This appeared to be a lupus erythematosus-like eruption due to an adverse drug reaction to D-penicillamine be...
journal_title:International journal of dermatology
pub_type: 杂志文章
doi:10.1111/j.1365-4362.1990.tb03471.x
更新日期:1990-10-01 00:00:00
abstract:BACKGROUND:The reported efficacy and safety of some biologic agents for psoriasis vary between Caucasians and Asians. Few reports of etanercept exist in psoriasis patients within the Asia-Pacific region. OBJECTIVES:The study aims to report our clinical experience of etanercept in the treatment of patients with moderat...
journal_title:International journal of dermatology
pub_type: 杂志文章
doi:10.1111/j.1365-4632.2011.05273.x
更新日期:2013-06-01 00:00:00
abstract::Nine patients with cutaneous toxoplasmosis had slowly regressing erythema-multiforme-like eruptions or lichenoid, papulonodular and purpurictelangiectatic disorders. The most common histologic finding was subacute histiolymphocytic perivasculitis with frequent demonstration of the parasite. Another group of patients s...
journal_title:International journal of dermatology
pub_type: 杂志文章
doi:10.1111/j.1365-4362.1980.tb00351.x
更新日期:1980-07-01 00:00:00
abstract::A 40-year-old black man who was HIV positive developed generalized hypertrophic lichen planus in areas previously affected by a photosensitivity eruption. After unsuccessful attempts to induce remission of his lichen planus with conventional therapies, etretinate produced a dramatic response. ...
journal_title:International journal of dermatology
pub_type: 杂志文章
doi:10.1111/j.1365-4362.1988.tb02423.x
更新日期:1988-11-01 00:00:00
abstract::An 11-year-old girl presented from Villa Azueta, Veracruz, a poor and small town on the Tesechoacan riverside. The Tesechoacan riverside is a tropical area in the south-east of Mexico, between 18 degrees, 04',32" latitude and 95 degrees, 42',23" longitude. Her family consisted of both parents and 12 brothers, all appa...
journal_title:International journal of dermatology
pub_type: 杂志文章
doi:10.1111/j.1365-4362.1997.tb03307.x
更新日期:1997-01-01 00:00:00
abstract:BACKGROUND:Huntington interacting protein 1 (HIP1), an antiapoptotic protein normally expressed in the brain, is highly expressed in Merkel cell carcinomas (MCCs). Given this, the aim of the current study was to ascertain the value of HIP1 as a histopathologic adjunct in the diagnosis of MCC. METHODS:In this retrospec...
journal_title:International journal of dermatology
pub_type: 杂志文章
doi:10.1111/ijd.12454
更新日期:2015-06-01 00:00:00
abstract:BACKGROUND:Castleman disease (CD) is a lymphoproliferative B-cell disease that is diagnosed from lymphoid hyperplasia with vascular proliferation. Symptoms may include fever, night sweats, and weight loss. Cutaneous manifestations often may go unnoticed since little has been described in the literature regarding them. ...
journal_title:International journal of dermatology
pub_type: 杂志文章
doi:10.1111/ijd.15043
更新日期:2020-10-01 00:00:00
abstract:BACKGROUND:Prompt management of acute graft-versus-host disease (GVHD) may prevent its morbidity and mortality. Maculopapular (MP) eruption is a presenting sign of acute GVHD, but differentiation from other causes of MP rash is challenging. METHODS:A retrospective study was conducted among patients developing MP erupt...
journal_title:International journal of dermatology
pub_type: 杂志文章
doi:10.1111/ijd.15186
更新日期:2021-01-01 00:00:00
abstract::Pellagra secondary to antituberculous chemotherapy can result from isoniazide therapy, as well as from pyrazinamide treatment. Because of the similarity in structural formulas between pyrazinamide, isoniazide, and nicotinamide, the substrate competition is the mechanism most likely involved. The patient was cured by a...
journal_title:International journal of dermatology
pub_type: 杂志文章
doi:10.1111/j.1365-4362.1983.tb02114.x
更新日期:1983-01-01 00:00:00
abstract::In a randomized, double-blind, parallel comparative study of 80 patients, impetigo and ecthyma were treated effectively by sulconazole nitrate 1% cream and miconazole nitrate 2% cream applied to lesions twice daily for 14 days. When treatment began, bacterial cultures from all pyodermal lesions yielded Group A beta-he...
journal_title:International journal of dermatology
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1111/j.1365-4362.1988.tb01273.x
更新日期:1988-12-01 00:00:00
abstract:BACKGROUND:Onchocerciasis, an infection by the filarial nematode Onchoverca volvulus, is widely distributed in tropical Africa and of great dermatologic interest. This study analyses the dermatologic presentation and tries to determine the correlations between clinical disease and host parasite interactions in onchocer...
journal_title:International journal of dermatology
pub_type: 杂志文章
doi:10.1046/j.1365-4362.1997.00007.x
更新日期:1997-01-01 00:00:00
abstract:BACKGROUND:Prurigo pigmentosa (PP), a rare inflammatory disease of the skin, is mostly reported in the ethnic Japanese population. Its pathogenesis remains unclear. The chronic and recurrent nature of PP implies a possible role of viral infection in the pathogenesis. The anti-inflammatory mechanism of doxycycline, whic...
journal_title:International journal of dermatology
pub_type: 杂志文章
doi:10.1111/j.1365-4632.2010.04625.x
更新日期:2011-01-01 00:00:00
abstract::A 60-year-old man presented to the Emergency Department (ED) with large, painful, indurated plaques on the right thigh, left abdomen, left chest, and right chest, which began without any preceding trauma on the right thigh 3 weeks prior to presentation in the ED. He was initially treated with cefazolin 1 g three times...
journal_title:International journal of dermatology
pub_type: 杂志文章
doi:10.1111/j.1365-4632.2006.03067.x
更新日期:2007-10-01 00:00:00
abstract:BACKGROUND:Alopecia areata (AA) is a non-scarring, autoimmune, inflammatory hair loss disease. Zinc is a trace element involved in important functional activities of hair follicles. PURPOSE:To evaluate serum zinc levels in patients with newly diagnosed and resistant lesions of AA in comparison to age- and sex-matched ...
journal_title:International journal of dermatology
pub_type: 杂志文章
doi:10.1111/ijd.12769
更新日期:2016-01-01 00:00:00
abstract:BACKGROUND:Epoxy resin compounds (ERC) include a large number of sensitizing chemicals such as epoxy resins (ER), hardeners (curing agents), and reactive diluents. Allergic contact dermatitis (ACD) caused by ERCS is often occupational. MATERIALS AND METHODS:We report a patient, sensitized to a hardener of a two-compon...
journal_title:International journal of dermatology
pub_type: 杂志文章
doi:10.1111/j.1365-4362.1996.tb05050.x
更新日期:1996-12-01 00:00:00
abstract::The porphyrias are diverse in pathophysiology, clinical presentation, severity, and prognosis, presenting a diagnostic and therapeutic challenge. Although not easily curable, the dermatological manifestations of these diseases, photosensitivity and associated cutaneous pathology, can be effectively prevented and manag...
journal_title:International journal of dermatology
pub_type: 杂志文章,评审
doi:10.1111/ijd.12016
更新日期:2014-01-01 00:00:00
abstract::The biology of wound healing is indeed a complex process. From phase 1 to phase 3, an orderly progression of events take place in the repair process. Various factors influence the rapidity and cosmetic appearance of this phenomenon. Physical, microbial, nutritional and environmental factors all have some role in the e...
journal_title:International journal of dermatology
pub_type: 杂志文章,评审
doi:10.1111/j.1365-4362.1975.tb00088.x
更新日期:1975-12-01 00:00:00
abstract:BACKGROUND:Assessment of severity is essential in the clinical care of rosacea patients and in the research on rosacea. OBJECTIVE:To determine the range of methods used to assess rosacea severity in clinical trials. METHODS:The medical literature from 1965 through 2001 was searched for rosacea clinical trials using M...
journal_title:International journal of dermatology
pub_type: 杂志文章,评审
doi:10.1046/j.1365-4362.2003.01780.x
更新日期:2003-06-01 00:00:00
abstract:BACKGROUND:Diagnostic errors appear to be the most common, costly, and dangerous of all medical mistakes. There has been a notable increase on the focus of error prevention as part of a growing patient safety movement. However, diagnostic errors have received less attention than other types of error. Our goal is to pre...
journal_title:International journal of dermatology
pub_type: 杂志文章
doi:10.1111/ijd.13532
更新日期:2017-06-01 00:00:00
abstract:BACKGROUND:The treatment of melanoma in situ (MIS), particularly the lentigo maligna (LM) subtype, has been a controversial subject in the literature for over a decade. Surgical excision with 5 mm margins is the standard of care in the USA, while several variations of Mohs surgery are frequently used to treat clinicall...
journal_title:International journal of dermatology
pub_type: 杂志文章,评审
doi:10.1111/j.1365-4632.2010.04423.x
更新日期:2010-05-01 00:00:00
abstract:BACKGROUND:Climatologic factors may affect atopic dermatitis (AD), and there have been few explorations into this topic. Because of its size, the United States (US) has a broad range of climates. The objective of this study is to assess the relationship between ambulatory office visits physicians for AD with temperatur...
journal_title:International journal of dermatology
pub_type: 杂志文章
doi:10.1111/ijd.14289
更新日期:2019-04-01 00:00:00
abstract::With more than 3 years' follow-up, dramatic clinical transfiguration of granuloma annulare was observed in a 59-year-old man with perforating granuloma annulare. The eruption was at first localized, then became generalized, developed perforations, and subsided in parallel with the improvement of associated diabetes me...
journal_title:International journal of dermatology
pub_type: 杂志文章
doi:10.1111/j.1365-4362.1985.tb05855.x
更新日期:1985-11-01 00:00:00
abstract::Although tamoxifen (TAM) is routinely used in advanced melanoma, it is still uncertain whether evidence exists to support this practice. This review assesses the benefits and harms of systemic therapy with TAM vs. without TAM on response and mortality in patients with advanced melanoma. MEDLINE, The Cochrane Database ...
journal_title:International journal of dermatology
pub_type: 杂志文章,meta分析,评审
doi:10.1111/j.1365-4632.2010.04529.x
更新日期:2010-10-01 00:00:00
abstract::Vitiligo is one of the most important skin disorders that does not cause much physical impairment, but due to its disfiguring appearance, patients have disturbances in mental health and quality of life (QoL). The dermatology life quality index (DLQI), as one of the most specific QoL instruments, is now used widely for...
journal_title:International journal of dermatology
pub_type: 杂志文章,评审
doi:10.1111/ijd.13198
更新日期:2016-06-01 00:00:00
abstract:OBJECTIVE:This study analyzes the major clinical characteristics of patients with active leprosy in relation to the in vitro immune response to the T-lymphocyte activator anti-CD3. METHODS:Thirty-eight patients with an established diagnosis of leprosy were classified according to the Ridley and Jopling table. Peripher...
journal_title:International journal of dermatology
pub_type: 杂志文章
doi:10.1111/j.1365-4362.1996.tb02974.x
更新日期:1996-11-01 00:00:00
abstract:BACKGROUND:The Section of Dermatology of the University of the Philippines, Philippine General Hospital, reported a case of chronic arsenic poisoning from a community in Luzon island to the Department of Health resulting in the conduct of two health and environmental assessment missions in December 2014. OBJECTIVE:To ...
journal_title:International journal of dermatology
pub_type: 杂志文章
doi:10.1111/ijd.13615
更新日期:2017-07-01 00:00:00
abstract:BACKGROUND:In vitiligo, other than loss of melanocytes and melanin pigment in the lesional skin, keratinocytes are also involved. Human fetal Merkel cells are now generally considered to be derived from the epidermis. To date, no observations on Merkel cells in lesional skin of active vitiligo have been reported. METH...
journal_title:International journal of dermatology
pub_type: 杂志文章
doi:10.1111/j.1365-4362.1994.tb02859.x
更新日期:1994-07-01 00:00:00