Reaction in leprosy: acute phase reactant response during and after remission.

Abstract:

:Sera from 25 patients with type 1 (Lepra), upgrading and downgrading, and type 2 (erythema nodosum leprosum [ENL]) reactions were assayed, during the reaction and after its clinical remission, for changes in levels of alpha-1-antitrypsin (A1A) and C-reactive protein (CRP). The results were compared with those from normal healthy adults and patients of leprosy without history and/or clinical evidence of reaction. The A1A levels correlated better with changes in status of type 1 reaction; whereas CRP levels correlated well with alterations in type 2 reactions and were definitely superior to A1A in this situation for monitoring the course of these episodes.

journal_name

Int J Dermatol

authors

Sehgal VN,Bhattacharya SN,Shah Y,Sharma VK,Gupta CK

doi

10.1111/j.1365-4362.1992.tb03981.x

subject

Has Abstract

pub_date

1992-09-01 00:00:00

pages

632-4

issue

9

eissn

0011-9059

issn

1365-4632

journal_volume

31

pub_type

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