Nail pigmentation due to hydroxycarbamide.

Abstract:

:A 47-year-old male developed both longitudinal melanonychia and periungual hyperpigmentation 6 months after initiation of hydroxycarbamide (synonym: hydroxyurea) therapy for chronic myeloproliferative disease. Based on the clinical symptoms observed in this patient, the broad differential diagnostic spectrum of hyperpigmentation of the nails is briefly reviewed here. In individuals who undergo hydroxycarbamide treatment, melanonychia might sometimes be seen as side effect and always has to be differentiated from subungual malignant melanoma.

journal_name

Int J Dermatol

authors

Ceulen RP,Frank J,Poblete-Gutiérrez P

doi

10.1111/j.1365-4632.2007.03502.x

subject

Has Abstract

pub_date

2007-11-01 00:00:00

pages

13-5

eissn

0011-9059

issn

1365-4632

pii

IJD3502

journal_volume

46 Suppl 3

pub_type

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