Abstract：
BACKGROUND:The literature includes only a few reports of oral isotretinoin for the treatment of folliculitis decalvans (FD). This study aimed to determine the most effective dose and duration of oral isotretinoin monotherapy for achieving remission in FD patients. METHODS:This retrospective case series study included FD patients that were treated with oral isotretinoin. Patient demographics, clinical characteristics, and treatment details were obtained from the patients' medical records. Patients were contacted via telephone after treatment was completed and asked about any relapses, time period of relapses, and the long-term effects of the treatment. RESULTS:The study included 39 male patients with a mean age of 37.9 ± 15.5 years. All of the patients received oral isotretinoin 0.1-1.02 mg/kg/day (10-90 mg/day) for a median duration of 2.5 months (range: 1-8 months). In all, 82.0% of patients healed after the treatment. Patients that received oral isotretinoin ≥0.4 mg/kg/day for ≥3 months responded better, and 66% of them never relapsed. CONCLUSION:Contrary to general belief, oral isotretinoin monotherapy resulted in complete response in the majority of patients in this study. Based on this finding, we think oral isotretinoin ≥0.4 mg/kg/day should be given for ≥3 months to minimize the likelihood of relapse. In addition, we think oral isotretinoin monotherapy should be considered a promising treatment alternative for FD that warrants further research.
journal_name
Int J Dermatoljournal_title
International journal of dermatologyauthors
Aksoy B,Hapa A,Mutlu Edoi
10.1111/ijd.13874subject
Has Abstractpub_date
2018-02-01 00:00:00pages
250-253issue
2eissn
0011-9059issn
1365-4632journal_volume
57pub_type
杂志文章abstract：BACKGROUND:Prompt management of acute graft-versus-host disease (GVHD) may prevent its morbidity and mortality. Maculopapular (MP) eruption is a presenting sign of acute GVHD, but differentiation from other causes of MP rash is challenging. METHODS:A retrospective study was conducted among patients developing MP erupt...
journal_title：International journal of dermatology
pub_type： 杂志文章
doi：10.1111/ijd.15186
更新日期：2021-01-01 00:00:00
abstract：BACKGROUND:Climatologic factors may affect atopic dermatitis (AD), and there have been few explorations into this topic. Because of its size, the United States (US) has a broad range of climates. The objective of this study is to assess the relationship between ambulatory office visits physicians for AD with temperatur...
journal_title：International journal of dermatology
pub_type： 杂志文章
doi：10.1111/ijd.14289
更新日期：2019-04-01 00:00:00
abstract：BACKGROUND:The relationship between infantile seborrheic dermatitis (ISD) and infantile atopic dermatitis (IAD) is controversial. METHODS:Ninety-six children aged 2-12 months diagnosed with atopic dermatitis and a comparable control group of healthy children were evaluated. Demographic data, personal history of ISD an...
journal_title：International journal of dermatology
pub_type： 杂志文章
doi：10.1046/j.1365-4362.2002.01497.x
更新日期：2002-06-01 00:00:00
abstract：BACKGROUND:Lichen planus pigmentosus inversus (LPPI) is a rare variant of LP. Only 31 cases have been reported in the literature. METHODS:Here we report a series of 10 patients with LPPI from North Africa. RESULTS:Ten cases of LPPI, clinically suspected and histologically confirmed, were seen over 3 years (2013-2015)...
journal_title：International journal of dermatology
pub_type： 杂志文章
doi：10.1111/ijd.13295
更新日期：2016-10-01 00:00:00
abstract：BACKGROUND:Methicillin-resistant Staphylococcus aureus (MRSA) is an important nosocomial pathogen. It can also cause community-acquired infections. Indian reports about MRSA in community-acquired infections are rare. AIM:To evaluate the rate of MRSA in community-acquired pyoderma and the nasal colonisation with S. aur...
journal_title：International journal of dermatology
pub_type： 杂志文章
doi：10.1111/j.1365-4632.2004.02138.x
更新日期：2004-06-01 00:00:00
abstract：BACKGROUND AND OBJECTIVE:The improvement of acne in summertime or the aggravation of acne in winter is a traditional dermatologic opinion. Ultraviolet rays are thought to be beneficial in the treatment of acne. In the existing literature there is no proof of this. The purpose of this study was to find out whether or no...
journal_title：International journal of dermatology
pub_type： 杂志文章
doi：10.1111/j.1365-4362.1996.tb03274.x
更新日期：1996-02-01 00:00:00
abstract：BACKGROUND:Clindamycin phosphate (CLDMP) is effective against Gram-positive and anaerobic bacteria, and is known to have anti-inflammatory properties. METHODS:To further study the anti-inflammatory properties of CLDMP, we examined the scavenging effects on superoxide anion and hydroxyl radical using an electron spin r...
journal_title：International journal of dermatology
pub_type： 杂志文章
doi：10.1111/j.1365-4632.2007.03338.x
更新日期：2007-11-01 00:00:00
abstract：BACKGROUND:Papulonecrotic tuberculid is a rarely reported cutaneous reaction to the mycobacterium bacillus. It is most often encountered in association with tuberculosis. The clinical and histologic picture of the entity is a distinctive one, but the etiology of the disease process is uncertain. Therapy directed agains...
journal_title：International journal of dermatology
pub_type： 杂志文章
doi：10.1111/j.1365-4362.1994.tb01537.x
更新日期：1994-02-01 00:00:00
abstract：:Clinical, histologic, and immunofluorescence studies were performed in 15 patients with pemphigus herpetiformis. The initial diagnosis was dermatitis herpetiformis, IgA linear bullous dermatosis or bullous pemphigoid. The histology varied depending on the character of skin lesions, and showed eosinophilic spongiosis o...
journal_title：International journal of dermatology
pub_type： 杂志文章
doi：10.1111/j.1365-4362.1987.tb02308.x
更新日期：1987-11-01 00:00:00
abstract：:Oral mucous membrane involvement occurs uncommonly in mycosis fungoides and reports of it are scarce. We present two patients with severe involvement of the oral mucous membranes. ...
journal_title：International journal of dermatology
pub_type： 杂志文章
doi：10.1111/j.1365-4362.1991.tb04353.x
更新日期：1991-12-01 00:00:00
abstract：BACKGROUND:Postherpetic neuralgia, a common sequele to herpes zoster infection, is a chronic debilitating problem. The available therapeutic modalities are usually ineffective. METHODS:A total of 3960 patients (1326 women and 2634 men; age group, 21-84 years), with postherpetic neuralgia as the presenting complaint an...
journal_title：International journal of dermatology
pub_type： 临床试验,杂志文章
doi：10.1046/j.1365-4362.1998.00392.x
更新日期：1998-06-01 00:00:00
abstract：:Twenty-eight psoriatic patients received PUVA treatment (psoralen and long ultraviolet irradiations. Two preparations were used; 8-methoxypsoralen and a mixture of 5-methoxypsoralen and 8-methoxypsoralen. Both gave considerable improvement, but in 6 cases the lesions reappeared after 2 to 8 weeks, in spite of maintena...
journal_title：International journal of dermatology
pub_type： 杂志文章
doi：10.1111/j.1365-4362.1976.tb01829.x
更新日期：1976-11-01 00:00:00
abstract：BACKGROUND:Tinea capitis is a dermatophyte infection of the scalp, eyebrows, and eyelashes caused by species of Microsporum and Trichophyton. The purpose of this study was to discover the incidence and causal agents of tinea capitis in Saudi Arabia. METHODS:Hair roots, skin scrapings, and pus swabs were collected from...
journal_title：International journal of dermatology
pub_type： 杂志文章
doi：10.1111/j.1365-4362.1993.tb00961.x
更新日期：1993-01-01 00:00:00
abstract：BACKGROUND:The diagnosis of Japan spotted fever (JSF) is very difficult in some cases. The initial diagnosis of JSF is very important to treat. METHODS:We report nine cases of Japan spotted fever (JSF) with variable clinical features diagnosed at our hospital in 2008. RESULTS:Concerning clinical symptom, the most fre...
journal_title：International journal of dermatology
pub_type： 杂志文章
doi：10.1111/j.1365-4632.2010.04359.x
更新日期：2010-04-01 00:00:00
abstract：BACKGROUND:Onychomycosis, a fungal infection of the nail, is caused by dermatophytes, yeasts, and nondermatophyte molds. The causative pathogen and incidence of onychomycosis depend on age, gender, geographic and climatic conditions, living habits, and immune status of the host. AIM:To determine the incidence and etio...
journal_title：International journal of dermatology
pub_type： 杂志文章
doi：10.1111/j.1365-4632.2009.04126.x
更新日期：2009-09-01 00:00:00
abstract：BACKGROUND:Though acral lentiginous melanoma (ALM) is a major type of malignant melanoma, no immunohistochemical study on this type of melanoma has been reported. OBJECTIVE:The purpose of this study is to analysis the immunohistochemical findings of ALM using routinely used immune markers. METHODS:An immunohistochemi...
journal_title：International journal of dermatology
pub_type： 杂志文章
doi：10.1046/j.1365-4362.2003.01583.x
更新日期：2003-02-01 00:00:00
abstract：OBJECTIVE:We performed a prospective study to evaluate the diagnostic accuracy of cytologic examination in basal cell carcinomas (BCCs) and squamous cell carcinomas (SCCs), in order to assess its clinical value. Study design Samples were taken by the "scraping" technique which involves scraping with a scalpel blade dir...
journal_title：International journal of dermatology
pub_type： 杂志文章
doi：10.1046/j.1365-4362.2000.00893.x
更新日期：2000-02-01 00:00:00
abstract：INTRODUCTION:Treatment of keloids is a challenge as a result of paucity of effective treatment modalities, significant side effects, and their recurrent nature. In this study, various treatment modalities were compared to search for a treatment option with maximum efficacy and minimum side effects. METHODS:One hundred...
journal_title：International journal of dermatology
pub_type： 杂志文章,随机对照试验
doi：10.1111/ijd.14069
更新日期：2018-10-01 00:00:00
abstract：:Histoid leprosy is a rare variant of leprosy with a unique clinical presentation and bacilli rich histology. These patients are large reservoirs for disease and vectors for spread, making prompt diagnosis and treatment crucial. To date, no consensus on treatment and duration exists. This paper aims to investigate the ...
journal_title：International journal of dermatology
pub_type： 杂志文章,评审
doi：10.1111/ijd.14962
更新日期：2020-10-01 00:00:00
abstract：BACKGROUND:Khite (also known as fatlah in Egypt) is a manual technique of temporary vellus hair removal that is widely performed in the Middle East. METHODS:The technique of khite is reviewed as illustrated. RESULTS:Khite is an effective method of removing unwanted vellus hairs. CONCLUSIONS:Dermatologists in all par...
journal_title：International journal of dermatology
pub_type： 杂志文章
doi：10.1046/j.1365-4362.1997.00189.x
更新日期：1997-03-01 00:00:00
abstract：BACKGROUND:Ant sting reactions are becoming an increasing problem in tropical countries. It is important for physicians to be aware of their possible cutaneous and systemic manifestations. METHODS:A child with a severe allergic reaction to an ant sting was examined and is discussed. This is the first case described in...
journal_title：International journal of dermatology
pub_type： 杂志文章
doi：10.1046/j.1365-4362.2002.01480.x
更新日期：2002-11-01 00:00:00
abstract：BACKGROUND:Herpes simplex virus (HSV) infections are usually chronically recurrent in the normal population and represent a significant cause of morbidity in immunocompromised patients. Acyclovir (ACV) is widely used for the treatment and prophylaxis of HSV infections. The emergence of ACV-resistant strains has been fr...
journal_title：International journal of dermatology
pub_type： 杂志文章
doi：10.1111/j.1365-4632.2007.03449.x
更新日期：2007-12-01 00:00:00
abstract：:The effects of prednisone, oral acyclovir, and radiotherapy were compared with placebo in the prevention of post-herpetic neuralgia. No treatment used was able to prevent, with statistical significance, post-herpetic neuralgia, although prednisone and acyclovir showed some pain reduction in the acute phase. Radiothera...
journal_title：International journal of dermatology
pub_type： 临床试验,杂志文章,随机对照试验
doi：10.1111/j.1365-4362.1991.tb04642.x
更新日期：1991-04-01 00:00:00
abstract：BACKGROUND:Several case reports and case series have recently explored the association between hidradenitis suppurativa (HS) and inflammatory bowel disease (IBD). OBJECTIVE:We performed a systematic review and meta-analysis of case-control studies to determine (i) the pooled prevalence of IBD in HS cohorts, and (ii) ...
journal_title：International journal of dermatology
pub_type： 杂志文章,meta分析
doi：10.1111/ijd.14697
更新日期：2020-02-01 00:00:00
abstract：BACKGROUND:The reported efficacy and safety of some biologic agents for psoriasis vary between Caucasians and Asians. Few reports of etanercept exist in psoriasis patients within the Asia-Pacific region. OBJECTIVES:The study aims to report our clinical experience of etanercept in the treatment of patients with moderat...
journal_title：International journal of dermatology
pub_type： 杂志文章
doi：10.1111/j.1365-4632.2011.05273.x
更新日期：2013-06-01 00:00:00
abstract：:The correlation between combined chemotherapy, including 6-mercaptopurine, and development of excessive number of melanocytic nevi in childhood has been previously reported and studied. As of yet, no such relation has been reported in adults. We recently observed a 27-year-old female patient who developed numerous ben...
journal_title：International journal of dermatology
pub_type： 杂志文章
doi：10.1111/j.1365-4632.2005.02086.x
更新日期：2005-04-01 00:00:00
abstract：BACKGROUND:Chemotherapy-induced acral erythema is a distinct localized cutaneous response to certain systemic chemotherapeutic agents. METHODS:Between January 1990 and December 1994, from a total of 76 leukemic patients who have received combination chemotherapy consisting of cytosine arabinoside and anthracycline ant...
journal_title：International journal of dermatology
pub_type： 杂志文章
doi：10.1046/j.1365-4362.1997.00040.x
更新日期：1997-08-01 00:00:00
abstract：BACKGROUND:Skin problems in the elderly population have rarely been the subject of scientific research. OBJECTIVES:The present study aimed to determine the prevalences of the most common dermatological conditions in elderly subjects and to investigate their associations with systemic diseases. METHODS:The study invol...
journal_title：International journal of dermatology
pub_type： 杂志文章
doi：10.1111/ijd.12832
更新日期：2015-09-01 00:00:00
abstract：BACKGROUND:Cutaneous larva migrans (CLM) is caused by the penetration of larvae of animal hookworms into the skin. Knowledge about this ectoparasitosis is mainly based on the examination of travelers or other expatriates. Population-based studies in an endemic area have never been performed. METHODS:A representative p...
journal_title：International journal of dermatology
pub_type： 杂志文章
doi：10.1111/j.1365-4632.2004.02152.x
更新日期：2004-07-01 00:00:00
abstract：BACKGROUND:Cutaneous lymphomas are a heterogeneous group of tumors with various clinical manifestations, histological features, and prognoses. METHODS:Among 425 cases of cutaneous lymphoma, we describe eight cases of peripheral T-cell lymphoma, unspecified, presenting with generalized benign-looking dermatitis. RESUL...
journal_title：International journal of dermatology
pub_type： 杂志文章
doi：10.1111/ijd.13493
更新日期：2017-06-01 00:00:00
