Abstract:
:The correlation between combined chemotherapy, including 6-mercaptopurine, and development of excessive number of melanocytic nevi in childhood has been previously reported and studied. As of yet, no such relation has been reported in adults. We recently observed a 27-year-old female patient who developed numerous benign melanocytic nevi during a 20-month period while taking 6-mercaptopurine for Crohn's disease. The appearance of many nevi was worrisome to the patient from a cosmetic and medical perspective (given the higher risk of melanoma associated with large numbers of nevi).
journal_name
Int J Dermatoljournal_title
International journal of dermatologyauthors
Kakrida M,Orengo I,Markus Rdoi
10.1111/j.1365-4632.2005.02086.xsubject
Has Abstractpub_date
2005-04-01 00:00:00pages
334-6issue
4eissn
0011-9059issn
1365-4632pii
IJD2086journal_volume
44pub_type
杂志文章abstract:OBJECTIVES:Oral lichen planus (OLP) is a chronic inflammatory disease of unknown cause. Malignant transformation in OLP lesions may be favored by changes in the expression of proteins that regulate cell proliferation and apoptosis. This study aimed to investigate these issues by immunohistochemical staining for Bcl-2 a...
journal_title:International journal of dermatology
pub_type: 杂志文章
doi:10.1111/ijd.12279
更新日期:2015-02-01 00:00:00
abstract:OBJECTIVE:This study analyzes the major clinical characteristics of patients with active leprosy in relation to the in vitro immune response to the T-lymphocyte activator anti-CD3. METHODS:Thirty-eight patients with an established diagnosis of leprosy were classified according to the Ridley and Jopling table. Peripher...
journal_title:International journal of dermatology
pub_type: 杂志文章
doi:10.1111/j.1365-4362.1996.tb02974.x
更新日期:1996-11-01 00:00:00
abstract:BACKGROUND:Phototherapy is already established as an effective mode of therapy in vitiligo. An evidence-based study was carried out of the effect of narrow-band (311 nm) ultraviolet-B (NB-UV-B) radiation in 66 surgically treated patients with recalcitrant vitiligo in whom autologous mini-punch grafting was deployed. M...
journal_title:International journal of dermatology
pub_type: 杂志文章,多中心研究
doi:10.1111/j.1365-4632.2005.02697.x
更新日期:2006-06-01 00:00:00
abstract:BACKGROUND:Pemphigoid gestationis (PG), also called herpes gestationis, is a rare autoimmune disease of pregnancy or puerperium (estimated 1 out of 50,000 pregnancies among Caucasians). A previous series has demonstrated an association of PG with human leukocyte antigen (HLA)-DR3 or HLA-DR4 haplotypes. While these hapl...
journal_title:International journal of dermatology
pub_type: 杂志文章
doi:10.1046/j.1365-4362.1999.00524.x
更新日期:1999-01-01 00:00:00
abstract:BACKGROUND:Sunbathing on the beach is one of the main risks for skin cancer. OBJECTIVE:In the summer of 2010, a skin cancer prevention campaign aimed at beachgoers was undertaken on the western Costa del Sol (southern Spain). METHODS:The campaign took place on beaches during July and August. A multicomponent interven...
journal_title:International journal of dermatology
pub_type: 杂志文章
doi:10.1111/ijd.12389
更新日期:2014-11-01 00:00:00
abstract:BACKGROUND:COVID-19 cutaneous manifestations have been recently described and classified in five different clinical patterns, including acral erythema-edema (pseudo-chilblain), maculopapular exanthemas, vesicular eruptions, urticarial lesions, and livedo or necrosis. OBJECTIVES:The objective of this study was to exami...
journal_title:International journal of dermatology
pub_type: 杂志文章
doi:10.1111/ijd.15180
更新日期:2020-09-24 00:00:00
abstract:BACKGROUND:Though melasma is a common skin condition in India, epidemiological studies are few and geographically confined. The present study was designed to gain insights into factors involved in causation and aggravation of melasma, demographic distribution, clinical presentations, and treatment patterns. METHODS:A ...
journal_title:International journal of dermatology
pub_type: 杂志文章,多中心研究
doi:10.1111/ijd.14541
更新日期:2019-11-01 00:00:00
abstract::Challenge: Balancing patient-centered clinical care with learner-centered teaching in a clinical setting becomes particularly challenging when it comes to teaching procedures to trainees (e.g. biopsies, excisions, etc.). How can procedures be taught in a way that reinforces repetition and mastery without compromising ...
journal_title:International journal of dermatology
pub_type: 杂志文章
doi:10.1111/ijd.13780
更新日期:2018-09-01 00:00:00
abstract:BACKGROUND:β-Cyclodextrin (βCD) xerogel containing silk fibroin (SF) was prepared, and the efficacy of the xerogel for a pressure sore developed on the back of an ICR mouse was investigated. MATERIALS AND METHODS:Tosyl βCD was conjugated to polyethyleneimine (PEI), and the βCD residues were cross-linked in an aqueous ...
journal_title:International journal of dermatology
pub_type: 杂志文章
doi:10.1111/j.1365-4632.2011.05389.x
更新日期:2012-08-01 00:00:00
abstract::Psoriasis is a chronic inflammatory skin disorder which can impair general routine activities and has been closely related to poor quality of life. Pruritus and scratching are frequently observed, occurring mainly during sleep and precipitating nighttime arousals. Indeed, sleep quality has been shown to be negatively ...
journal_title:International journal of dermatology
pub_type: 杂志文章,评审
doi:10.1111/ijd.13026
更新日期:2015-12-01 00:00:00
abstract::A 30-year-old woman presented with an orange-yellow discoloration of the skin, most noticeable on the palms and soles and nasolabial folds; sclera appeared normal. The patient had observed the abnormal pigmentation of her skin 3 months earlier and noticed that it had become more evident after a sauna she had taken 2 d...
journal_title:International journal of dermatology
pub_type: 杂志文章
doi:10.1111/j.1365-4362.1992.tb03521.x
更新日期:1992-01-01 00:00:00
abstract::A 58-year-old woman with ulcerative colitis of 5 years' duration was first seen in March 2002 with a 5-month history of widespread erosions on the palate and gingiva, subtle scarring of the conjunctiva, and xerostomia accompanying a flare of ulcerative colitis. No skin lesions were observed. Direct immunofluorescence ...
journal_title:International journal of dermatology
pub_type: 杂志文章
doi:10.1111/j.1365-4632.2006.02961.x
更新日期:2007-03-01 00:00:00
abstract:BACKGROUND:Recently, the reactivation during treatment with tumor necrosis factor (TNF) blockers has exceptionally been described in patients with hepatitis B virus (HBV) antigen-negative (HBsAg). The objective was to evaluate the influence of anti-TNF agents in patients with psoriasis and serology suggesting past hepa...
journal_title:International journal of dermatology
pub_type: 杂志文章
doi:10.1111/ijd.12313
更新日期:2014-07-01 00:00:00
abstract::Squamous cell carcinoma (scc) of the skin was studied in two similar populations, one living in the temperate zone of Australia, the other living in the tropics. In the tropics, the patients were significantly younger, the man to woman ratio approached unity, and women had significantly more sccs on the legs. In the t...
journal_title:International journal of dermatology
pub_type: 杂志文章
doi:10.1111/j.1365-4362.1992.tb02697.x
更新日期:1992-07-01 00:00:00
abstract:BACKGROUND:Sporotrichosis is a chronic granulomatous infection caused by Sporothrichum schenckii. The disease has worldwide distribution. Majority of cases from India are reported from North-eastern states. METHODS:The demographic, clinico-investigative profile and therapeutic results of nine patients with cutaneous s...
journal_title:International journal of dermatology
pub_type: 杂志文章
doi:10.1111/j.1365-4632.2008.03538.x
更新日期:2008-04-01 00:00:00
abstract:BACKGROUND:Tick bites are dermatoses not commonly encountered in Korea. Recognizing their clinical signs as well as their histopathologic findings is important in making a diagnosis of tick-related dermatoses. The incidence and causative species are different depending on the geographic areas. The histopathologic findi...
journal_title:International journal of dermatology
pub_type: 杂志文章,评审
doi:10.1111/j.1365-4362.1994.tb02894.x
更新日期:1994-08-01 00:00:00
abstract:BACKGROUND:Mycosis fungoides has numerous clinical presentations. METHODS:We present two cases in which mycosis fungoides clinically mimicked reticular erythematous mucinosis. RESULTS:Both patients had extracutaneous involvement. One had a fatal outcome. CONCLUSIONS:We suggest that full systemic evaluation be perfor...
journal_title:International journal of dermatology
pub_type: 杂志文章
doi:10.1111/j.1365-4632.2004.02434.x
更新日期:2006-03-01 00:00:00
abstract:BACKGROUND:Selective depletion of CD4+ T lymphocytes is common in both primary and secondary immunodeficiencies. Idiopathic CD4+ T lymphocytopenia (ICL) cases are defined as a persistent CD4+ T lymphocyte count of less than 300x10(6) cells/L and/or less than 20% of the total T-cell count. METHOD:A 40-year-old woman, w...
journal_title:International journal of dermatology
pub_type: 杂志文章
doi:10.1046/j.1365-4362.1999.00364.x
更新日期:1999-02-01 00:00:00
abstract:BACKGROUND:Histoid leprosy (HL) is a highly bacilliferous form of leprosy which requires early diagnosis and management. Dermoscopy is a noninvasive diagnostic method for various malignant and nonmalignant disorders. The aim of this study was to describe the dermoscopic patterns of various types of HL lesions over diff...
journal_title:International journal of dermatology
pub_type: 杂志文章
doi:10.1111/ijd.14731
更新日期:2020-03-01 00:00:00
abstract:BACKGROUND:Postherpetic neuralgia, a common sequele to herpes zoster infection, is a chronic debilitating problem. The available therapeutic modalities are usually ineffective. METHODS:A total of 3960 patients (1326 women and 2634 men; age group, 21-84 years), with postherpetic neuralgia as the presenting complaint an...
journal_title:International journal of dermatology
pub_type: 临床试验,杂志文章
doi:10.1046/j.1365-4362.1998.00392.x
更新日期:1998-06-01 00:00:00
abstract:BACKGROUND:In this study, we have investigated the chemotherapeutic potential of a purple violet pigment (PVP), which was isolated from a previously undescribed Antarctic Janthinobacterium sp. (Ant5-2), against murine UV-induced 2237 fibrosarcoma and B16F10 melanoma cells. METHODS:The 2237, B16F10, C50, and NIH3T3 cel...
journal_title:International journal of dermatology
pub_type: 杂志文章
doi:10.1111/j.1365-4632.2010.04825.x
更新日期:2011-10-01 00:00:00
abstract::A 32-year-old Thai woman developed acquired hypertrichosis lanuginosa with generalized lanugo hair, deeply furrowed tongue, and keratosis pilaris. She had metastatic adenocarcinoma of the liver. A review of world literature reveals 24 cases of which 22 were associated with proven malignancies. Acquired hypertrichosis ...
journal_title:International journal of dermatology
pub_type: 杂志文章
doi:10.1111/j.1365-4362.1982.tb02043.x
更新日期:1982-12-01 00:00:00
abstract:BACKGROUND:Pediculosis, caused by head lice (Pediculidae: Pediculus humanus var. capitis), is experiencing a global resurgence, with the prevalence in primary schools averaging as high as 40% in some areas regardless of socioeconomic factors. Control efforts using chemical treatments are becoming increasingly ineffecti...
journal_title:International journal of dermatology
pub_type: 杂志文章
doi:10.1111/j.1365-4632.2007.03132.x
更新日期:2007-04-01 00:00:00
abstract::Despite an array of topical and systemic antifungal agents, cases of resistant dermatophytosis still exist. Use of naftifine, the first commercially available allylamine derivative, proved successful in the management of four such cases. ...
journal_title:International journal of dermatology
pub_type: 杂志文章
doi:10.1111/j.1365-4362.1991.tb02649.x
更新日期:1991-08-01 00:00:00
abstract:BACKGROUND:A 42-year-old male patient suffering from the rare Comèl-Netherton syndrome is reported, and the symptoms are discussed together with the results of light and electron microscopic examinations. CASE REPORT:Our case presented peeling skin syndrome type B with spontaneous, lifelong skin shedding with underlyi...
journal_title:International journal of dermatology
pub_type: 杂志文章
doi:10.1046/j.1365-4362.2002.01418.x
更新日期:2002-05-01 00:00:00
abstract:BACKGROUND:The majority of lasers used for hair removal target melanin as the chromophore. In contrast with other cutaneous applications of lasers, lasers used for hair removal must generate a limited, controlled degree of thermal damage to permanently remove hairs. AIM:To remove excess back hair from two male patient...
journal_title:International journal of dermatology
pub_type: 杂志文章
doi:10.1046/j.1365-4362.2001.01251.x
更新日期:2001-08-01 00:00:00
abstract:BACKGROUND:Pemphigus herpetiformis (PH) is a rare subtype of pemphigus that presents challenges in diagnosis. OBJECTIVE:To review the presentation, diagnosis, and management of PH. METHODS:We reviewed the charts of all patients diagnosed and treated for PH in an immunobullous referral center between September 2007 an...
journal_title:International journal of dermatology
pub_type: 杂志文章,评审
doi:10.1111/ijd.12582
更新日期:2015-09-01 00:00:00
abstract:BACKGROUND:Mycosis fungoides (MF) is the most common primary cutaneous T-cell lymphoma (CTCL), followed by CD30+ lymphoproliferative disorders, including lymphomatoid papulosis (LyP) and primary cutaneous anaplastic large cell lymphoma (pcALCL). The objective was to report on a series of patients with different types o...
journal_title:International journal of dermatology
pub_type: 杂志文章,评审
doi:10.1111/ijd.12847
更新日期:2016-02-01 00:00:00
abstract:BACKGROUND:Psoriasis has been associated with depressive disease and case reports of completed suicide. METHODS:217 consenting psoriasis patients completed the Carroll Rating Scale for Depression (CRSD), a 52-item self-rated scale, with four of the items directly addressing wishes to be dead and suicidal ideation. The...
journal_title:International journal of dermatology
pub_type: 杂志文章
doi:10.1111/j.1365-4362.1993.tb02790.x
更新日期:1993-03-01 00:00:00
abstract::A 40-year-old black man who was HIV positive developed generalized hypertrophic lichen planus in areas previously affected by a photosensitivity eruption. After unsuccessful attempts to induce remission of his lichen planus with conventional therapies, etretinate produced a dramatic response. ...
journal_title:International journal of dermatology
pub_type: 杂志文章
doi:10.1111/j.1365-4362.1988.tb02423.x
更新日期:1988-11-01 00:00:00