Lupus erythematosus-like eruption due to D-penicillamine in progressive systemic sclerosis.

Abstract:

:A 58-year-old woman with progressive systemic sclerosis developed a butterfly erythematous eruption, hemorrhagic maculae, crusting, and erosions on the face 15 days following administration of D-penicillamine. This appeared to be a lupus erythematosus-like eruption due to an adverse drug reaction to D-penicillamine because of the rapid recovery from the general symptoms, the total involution of skin lesions with topical treatment only, the transient demonstration of autoantibodies and their fast negativation, negative ANA, and the histologic features of lupus erythematosus combined with marked exudative changes.

journal_name

Int J Dermatol

authors

Tsankov NK,Lazarova AZ,Vasileva SG,Obreshkova EV

doi

10.1111/j.1365-4362.1990.tb03471.x

subject

Has Abstract

pub_date

1990-10-01 00:00:00

pages

571-4

issue

8

eissn

0011-9059

issn

1365-4632

journal_volume

29

pub_type

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