Abstract:
:Necrolytic migratory erythema (NME) is a rare skin disorder that is a cutaneous manifestation of the glucagonoma syndrome. It presents with annular eruptions of migrating erythematous papules and plaques with superficial epidermal necrosis, central flaccid bullae, and crusted erosions located primarily in the intertriginous areas. Treatment with the long-acting somatostatin analog Octreotide is a potential therapy to help ameliorate skin symptoms. We present a case of a patient with a 1-year history of a pancreatic glucagonoma that developed an ulcerated, plaque-like, weeping rash over multiple areas of their body despite current treatment with Octreotide and stable pancreatic tumor staging. The patient had a similar rash when initially diagnosed with a glucagonoma, and it quickly improved after Octreotide treatment. Clinical examination and biopsy were consistent with necrolytic migratory erythema due to an underlying glucagonoma. This rare case adds to our understanding of the clinical presentation of NME, as well as highlights the relapsing and remitting course, even if the underlying pancreatic tumor is stable and the patient is undergoing treatment.
journal_name
Int J Dermatoljournal_title
International journal of dermatologyauthors
Tolliver S,Graham J,Kaffenberger BHdoi
10.1111/ijd.13947subject
Has Abstractpub_date
2018-06-01 00:00:00pages
642-645issue
6eissn
0011-9059issn
1365-4632journal_volume
57pub_type
杂志文章,评审abstract:BACKGROUND:Sunbathing on the beach is one of the main risks for skin cancer. OBJECTIVE:In the summer of 2010, a skin cancer prevention campaign aimed at beachgoers was undertaken on the western Costa del Sol (southern Spain). METHODS:The campaign took place on beaches during July and August. A multicomponent interven...
journal_title:International journal of dermatology
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doi:10.1111/ijd.12389
更新日期:2014-11-01 00:00:00
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journal_title:International journal of dermatology
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abstract::We report the occurrence of myiasis owing to Dermatobia hominis (Dh) in a HIV-infected subject. HIV infection did not modify the pathogenicity of myiasis. However, the clinical presentation seemed unusual with voluminous inflammatory nodules. Use of topical ivermectin killed the larvae and facilitated their extraction...
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pub_type: 杂志文章
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更新日期:2005-10-01 00:00:00
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pub_type: 杂志文章,meta分析,评审
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更新日期:2016-05-01 00:00:00
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更新日期:2009-06-01 00:00:00
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pub_type: 杂志文章
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更新日期:2014-11-01 00:00:00
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journal_title:International journal of dermatology
pub_type: 杂志文章
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更新日期:2015-01-01 00:00:00
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pub_type: 杂志文章
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更新日期:2016-08-01 00:00:00
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journal_title:International journal of dermatology
pub_type: 杂志文章,随机对照试验
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更新日期:2016-02-01 00:00:00
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journal_title:International journal of dermatology
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pub_type: 临床试验,杂志文章
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更新日期:2008-11-01 00:00:00
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更新日期:2005-02-01 00:00:00