A confirmatory factor analytic evaluation of the pentagonal PANSS model.

abstract：OBJECTIVE:Patients with schizophrenia have a high prevalence of metabolic disorders and cardiovascular mortality. It is possible that a vulnerability to metabolic abnormalities is associated with risk for psychosis, symptoms and functionality. In this study, we evaluate demographic information, cardiometabolic indices,...

journal_title：Schizophrenia research

authors： Cadenhead KS,Minichino A,Kelsven S,Addington J,Bearden C,Cannon TD,Cornblatt BA,Mathalon D,McGlashan TH,Perkins DO,Seidman LJ,Tsuang M,Walker EF,Woods SW,Yao J,North American Prodromal Longitudinal Studies (NAPLS) consortiu

更新日期：2019-02-01 00:00:00

abstract：:Viral infections during fetal and adolescent periods, as well as during the course of schizophrenia itself have been linked to the onset and/or relapse of a psychosis. We previously reported that the unique antipsychotic aripiprazole, a partial D2 agonist, inhibits the release of tumor necrosis factor (TNF)-α from int...

journal_title：Schizophrenia research

authors： Sato-Kasai M,Kato TA,Ohgidani M,Mizoguchi Y,Sagata N,Inamine S,Horikawa H,Hayakawa K,Shimokawa N,Kyuragi S,Seki Y,Monji A,Kanba S

更新日期：2016-12-01 00:00:00

abstract：:While the long-term administration of antipsychotics is known to cause dopamine supersensitivity psychosis (DSP), recent studies revealed that DSP helps form the foundation of treatment resistance. Electroconvulsive shock (ES) is one of the more effective treatments for treatment-resistant schizophrenia. The objective...

journal_title：Schizophrenia research

authors： Kimura M,Oda Y,Oishi K,Yoshino K,Kimura H,Niitsu T,Kanahara N,Shirayama Y,Hashimoto K,Iyo M

更新日期：2021-01-08 00:00:00

abstract：BACKGROUND:The concept of dose equivalence of depot medication is important for many scientific and clinical purposes. METHODS:A systematic literature search on four second-generation antipsychotics available as long-acting injectable drugs and haloperidol was conducted. We used the minimum effective dose method which...

journal_title：Schizophrenia research

authors： Rothe PH,Heres S,Leucht S

更新日期：2018-03-01 00:00:00

abstract：BACKGROUND:Higher cognitive dysfunction, lower perceptual disturbance and its relation to the structures that implicate such processes have been considered as key features in patients with schizophrenia. However, little is known about the relationship between perceptual processing and structural deficits in ultra-high-...

journal_title：Schizophrenia research

authors： Shin KS,Jung WH,Kim JS,Jang JH,Hwang JY,Chung CK,Kwon JS

更新日期：2012-09-01 00:00:00

abstract：:This study was a preliminary open clinical trial aimed at exploring the hypothesis that estrogen may provide protection against schizophrenia in women. Eleven women with acute psychotic symptoms, as scored on the BPRS, SAPS and SANS, had 0.02 mg estradiol added to neuroleptic treatment for eight weeks. Their response ...

journal_title：Schizophrenia research

authors： Kulkarni J,de Castella A,Smith D,Taffe J,Keks N,Copolov D

更新日期：1996-07-05 00:00:00

abstract：:Studies suggest that the affective response is impaired in both schizophrenia and adolescent offspring of schizophrenia patients. Adolescent offspring of patients are developmentally vulnerable to impairments in several domains, including affective responding, yet the bases of these impairments and their relation to n...

journal_title：Schizophrenia research

authors： Barbour T,Murphy E,Pruitt P,Eickhoff SB,Keshavan MS,Rajan U,Zajac-Benitez C,Diwadkar VA

更新日期：2010-11-01 00:00:00

abstract：:Patients with schizophrenia demonstrate a generalized deficit across multiple cognitive domains. However, it is unknown whether this deficit is largely due to lower intelligence, or if there is an impact of schizophrenia which cannot be accounted for by measures of general intellectual ability (GIA). We created four I...

journal_title：Schizophrenia research

authors： Gray BE,McMahon RP,Gold JM

更新日期：2013-07-01 00:00:00

abstract：:High exposure to green space and natural environments has previously been associated with lower schizophrenia rates possibly through low air pollution and improved psychological restoration. Exposure to natural environments could explain the negative urban-rural gradient of schizophrenia, but it is unclear if all natu...

journal_title：Schizophrenia research

authors： Engemann K,Svenning JC,Arge L,Brandt J,Geels C,Mortensen PB,Plana-Ripoll O,Tsirogiannis C,Pedersen CB

更新日期：2020-02-01 00:00:00

abstract：BACKGROUND:Older paternal age predicts schizophrenia diagnosis in offspring. If this relationship reflects a pathogenic process, paternal age should predict the expression of subclinical schizophrenia liability (schizotypy). We hypothesized that paternal and maternal ages predict positive, negative, and disorganized fe...

journal_title：Schizophrenia research

authors： Grattan RE,Morton SE,Warhurst ES,Parker TR,Nicolson MP,Maha JLK,Linscott RJ

更新日期：2015-12-01 00:00:00

abstract：:Twenty-five schizophrenic patients diagnosed by DSM-III-R underwent event-related potentials and magnetic resonance imaging scans. Latency and amplitude of P300 waveform were measured using an auditory odd-ball paradigm. Anterior and posterior volumes of the superior temporal gyrus and medial temporal structure were m...

journal_title：Schizophrenia research

authors： Kawasaki Y,Maeda Y,Higashima M,Nagasawa T,Koshino Y,Suzuki M,Ide Y

更新日期：1997-08-29 00:00:00

abstract：BACKGROUND:To develop a pharmacokinetic-pharmacodynamic (PK-PD) model using individual-level data of Positive and Negative Syndrome Scale (PANSS) total score to characterize the antipsychotic drug effect taking into account the placebo effect and dropout rate. In addition, a clinical utility (CU) criterion that describ...

journal_title：Schizophrenia research

authors： Pilla Reddy V,Kozielska M,Suleiman AA,Johnson M,Vermeulen A,Liu J,de Greef R,Groothuis GM,Danhof M,Proost JH

更新日期：2013-05-01 00:00:00

abstract：:Converging lines of evidence implicate structural and functional abnormalities in the cerebellum in schizophrenia (SCZ). The cerebellar vermis is of particular interest given its association with clinical symptoms and cognitive deficits in SCZ and its known connections with cortical regions such as the prefrontal cort...

journal_title：Schizophrenia research

authors： Womer FY,Tang Y,Harms MP,Bai C,Chang M,Jiang X,Wei S,Wang F,Barch DM

更新日期：2016-10-01 00:00:00

abstract：:To investigate relationships between birth season and biological family history in schizophrenia, this study used a sample of schizophrenics that had the advantages of (a) particularly thorough diagnostic assessments of schizophrenics' relatives, including information from direct interviews as well as chart reviews, a...

journal_title：Schizophrenia research

authors： Kinney DK,Jacobsen B,Jansson L,Faber B,Tramer SJ,Suozzo M

更新日期：2000-08-03 00:00:00

abstract：BACKGROUND:Eye movement abnormalities have been identified in schizophrenia; however, their relevance to cognition is still unknown. In this study, we explored the general relationship between eye movements and cognitive function. METHODS:The three eye movement measures (scanpath length, horizontal position gain, and ...

journal_title：Schizophrenia research

authors： Morita K,Miura K,Fujimoto M,Yamamori H,Yasuda Y,Kudo N,Azechi H,Okada N,Koshiyama D,Ikeda M,Kasai K,Hashimoto R

更新日期：2019-07-01 00:00:00

abstract：:A number of recent studies have suggested that schizophrenia patients share metamemory deficits, particularly, a decreased ability to distinguish between errors and correct responses in terms of response confidence (i.e., decreased confidence gap): patients are over-confident in errors while at the same time being und...

journal_title：Schizophrenia research

authors： Moritz S,Woodward TS,Chen E

更新日期：2006-01-31 00:00:00

abstract：:Thirty-six subjects aged 16 years or older judged at risk for a first episode of psychosis within a North American multi-site study of the schizophrenia prodrome [McGlashan et al., Schizophr. Res. (2003); Miller et al., Schizophr. Res. (2003)] performed at levels intermediate to population norms and data reported for ...

journal_title：Schizophrenia research

authors： Hawkins KA,Addington J,Keefe RS,Christensen B,Perkins DO,Zipurksy R,Woods SW,Miller TJ,Marquez E,Breier A,McGlashan TH

更新日期：2004-04-01 00:00:00

abstract：BACKGROUND:Evidence indicating that symptoms of non-clinical psychosis (NCP) occur in 6-8% of the general population suggests that psychosis may occur across a continuum. Although a number of studies have examined environmental contributors, to date there have been few investigations of biological/genetic factors in th...

journal_title：Schizophrenia research

authors： Mittal VA,Smolen A,Dean DJ,Pelletier AL,Lunsford-Avery J,Smith A

更新日期：2012-09-01 00:00:00

abstract：:The guarantee of perceptual coherence for events through everyday life situations depends upon the capacity to correctly integrate series of multi-sensory experiences. Patients with schizophrenia have been shown to reveal a deficit in integrating, i.e., "binding", perceptual information together. However, results in t...

journal_title：Schizophrenia research

authors： Foucher JR,Lacambre M,Pham BT,Giersch A,Elliott MA

更新日期：2007-12-01 00:00:00

abstract：:The involvement of the gamma-aminobutyric acid (GABA) system in schizophrenia is suggested by postmortem studies and the common use of GABA receptor-potentiating agents in treatment. In a recent study, we used a benzodiazepine challenge to demonstrate abnormal GABAergic function during processing of negative visual st...

journal_title：Schizophrenia research

authors： Tso IF,Fang Y,Phan KL,Welsh RC,Taylor SF

更新日期：2015-10-01 00:00:00

abstract：BACKGROUND:Delusions of control are among the most distinctive and characteristic symptoms of schizophrenia. Several theories have been proposed that implicate aberrant communication between spatially disparate brain regions in the etiology of this symptom. Given that white matter fasciculi represent the anatomical inf...

journal_title：Schizophrenia research

authors： Whitford TJ,Kubicki M,Pelavin PE,Lucia D,Schneiderman JS,Pantelis C,McCarley RW,Shenton ME

更新日期：2015-01-01 00:00:00

abstract：:Verbal dichotic listening performance was examined in 42 right-handed men and women with DSM-IV-defined schizotypal personality disorder (SPD) and 68 right-handed controls. As expected, both male and female control groups showed a right ear advantage on a verbal dichotic listening task. Although SPD subjects in genera...

journal_title：Schizophrenia research

authors： Voglmaier MM,Seidman LJ,Niznikiewicz MA,Madan A,Dickey CC,Shenton ME,McCarley RW

更新日期：2009-12-01 00:00:00

abstract：:Studies of neurocognitive function in patients with schizophrenia use widely variable assessment techniques. Clinical trials assessing the cognitive enhancing effect of new medications have used neurocognitive assessment batteries that differed in content, length and administration procedures. The Brief Assessment of ...

journal_title：Schizophrenia research

authors： Keefe RS,Goldberg TE,Harvey PD,Gold JM,Poe MP,Coughenour L

更新日期：2004-06-01 00:00:00

abstract：INTRODUCTION:HTR2A gene has been the subject of numerous studies in psychiatric genetics because LSD, which resembles serotonin causes psychosis and atypical antipsychotic drugs target the HTR2A receptor. However, evidence for the role of HTR2A polymorphism(s) in schizophrenia (SCZ) and bipolar disorder (BD) has been e...

journal_title：Schizophrenia research

authors： Abdolmaleky HM,Yaqubi S,Papageorgis P,Lambert AW,Ozturk S,Sivaraman V,Thiagalingam S

更新日期：2011-07-01 00:00:00

abstract：:Past studies have demonstrated that the Brief Negative Symptom Scale (BNSS) has excellent psychometric properties in patients with schizophrenia. In the current study, we extended this literature by examining psychometric properties of the BNSS in outpatients diagnosed with bipolar disorder (n=46), outpatients with sc...

journal_title：Schizophrenia research

authors： Strauss GP,Vertinski M,Vogel SJ,Ringdahl EN,Allen DN

更新日期：2016-02-01 00:00:00

abstract：:The 24-h profiles of plasma melatonin and cortisol were evaluated in 7 drug-free male paranoid schizophrenics and in 7 healthy subjects matched to the patients for age, sex, body weight, height and season of testing. Blood samples were obtained at 20.00, 22.00, 24.00, 01.00, 02.00, 06.00, 08.00 and 12.00 h. Light was ...

journal_title：Schizophrenia research

authors： Monteleone P,Maj M,Fusco M,Kemali D,Reiter RJ

更新日期：1992-04-01 00:00:00

abstract：:Forensic patients with schizophrenia who had carried out a homicide scored higher on a measure of moral cognition (MFQ-30) than other violent patients. Neurocognitive impairment was associated with homicide by mediation via higher scores for in-group loyalty. ...

journal_title：Schizophrenia research

authors： O'Reilly K,O'Connell P,Corvin A,O'Sullivan D,Coyle C,Mullaney R,O'Flynn P,Grogan K,Richter M,Kennedy H

更新日期：2018-03-01 00:00:00

abstract：:In this study we use high resolution Magnetic Resonance imaging (MRI) and apply rigorous manual tracing criteria in order to assess volumetrically the prefrontal cortex (PFC) in schizophrenia. Previous MRI studies suggested PFC is included in neural systems necessary for emotional processing and cognition, and regiona...

journal_title：Schizophrenia research

authors： Ohtani T,Levitt JJ,Nestor PG,Kawashima T,Asami T,Shenton ME,Niznikiewicz M,McCarley RW

更新日期：2014-01-01 00:00:00

abstract：OBJECTIVE:The recovery movement is having a growing impact on policy for people with severe mental illness. The empirical literature on the recovery orientation, however, is scant, and no empirical conceptualization of recovery has been published. METHOD:We identified items reflecting recovery themes and measuring asp...

journal_title：Schizophrenia research

authors： Resnick SG,Fontana A,Lehman AF,Rosenheck RA

更新日期：2005-06-01 00:00:00

abstract：BACKGROUND:Cognitive Remediation (CR) is an evidence based treatment targeting cognitive and functional difficulties in people with psychosis. Despite the large number of effectiveness studies, only limited evidence exists for the active ingredients of this therapy. This study begins to fill this gap by exploring the r...

journal_title：Schizophrenia research

authors： Cella M,Wykes T

更新日期：2019-01-01 00:00:00