Validity of cancer-related fatigue instruments.

abstract：:Concerns about cross-allergenicity between sulfonamide antibiotics and nonantibiotic, sulfonamide-containing drugs persist and can complicate patients' drug therapy unnecessarily. No interaction between the human immune system and the sulfonamide functional group has been demonstrated. The immunologic determinant of t...

journal_title：Pharmacotherapy

authors： Brackett CC,Singh H,Block JH

更新日期：2004-07-01 00:00:00

abstract：STUDY OBJECTIVE:To describe the pharmacokinetics and pharmacodynamics of fludarabine in patients with rheumatoid arthritis (RA). DESIGN:Open-label, staggered trial conducted in conjunction with a phase I-II clinical trial. SETTING:Government research hospital. PATIENTS:Twenty-six patients with refractory RA. INTERV...

journal_title：Pharmacotherapy

authors： Knebel W,Davis JC Jr,Sanders WD,Fessler B,Yarboro C,Pucino F,Boumpas DT

更新日期：1998-11-01 00:00:00

abstract：:We cared for a 4-year-old patient who had undergone orthotopic liver transplantation and was placed on a ventilator for respiratory distress associated with Pneumocystis carinii pneumonia. The neuromuscular blocking agent pancuronium bromide 1.0-1.2 mg every hour as needed was used to facilitate artificial ventilation...

journal_title：Pharmacotherapy

authors： Haas JL,Shaefer MS,Miwa LJ,Wood RP,Shaw BW Jr

更新日期：1989-01-01 00:00:00

abstract：STUDY OBJECTIVE:To evaluate the success of an initial tobramycin dosing regimen to achieve target peak and trough concentrations in adult patients with pulmonary exacerbations of cystic fibrosis (CF). DESIGN:Retrospective single-center medical record review. SETTING:Large tertiary care academic medical center. PATIE...

journal_title：Pharmacotherapy

authors： Staubes BA,Metzger NL,Walker SD,Peasah SK

更新日期：2016-06-01 00:00:00

abstract：STUDY OBJECTIVE:To evaluate the efficacy, safety, and costs of rabbit antithymocyte globulin (TMG) induction in patients who received kidney transplants from living unrelated donors. DESIGN:Retrospective cohort study. SETTING:Large academic medical center. PATIENTS:Eighty-seven patients who received kidney transplan...

journal_title：Pharmacotherapy

authors： Miller JT,Collins CD,Stuckey LJ,Luan FL,Englesbe MJ,Magee JC,Park JM

更新日期：2009-10-01 00:00:00

abstract：:The prevalence of diabetes mellitus has grown to staggering numbers, and its incidence is expected to rise in the next 2 decades. The need for novel approaches to treat hyperglycemia cannot be ignored. Current agents have been shown to modestly improve glycemia and in some cases prevent complications of diabetes, but ...

journal_title：Pharmacotherapy

authors： Shah NK,Deeb WE,Choksi R,Epstein BJ

更新日期：2012-01-01 00:00:00

abstract：:Tobacco use continues to be a major cause of morbidity and mortality. Even with behavioral and pharmacologic treatment, long-term tobacco cessation rates are low. Electronic nicotine delivery systems, commonly referred to as electronic cigarettes or e-cigarettes, are increasingly used for tobacco cessation. Because e-...

journal_title：Pharmacotherapy

authors： Franks AS,Sando K,McBane S

更新日期：2018-05-01 00:00:00

abstract：STUDY OBJECTIVE:To assess the reproducibility of Naranjo Adverse Drug Reaction Probability Scale (APS) scores in published case reports. DESIGN:Reliability analysis. MEASUREMENTS AND MAIN RESULTS:Randomly selected case reports using the APS were identified from the Web of Science database. The APS scores were blinded...

journal_title：Pharmacotherapy

authors： Liang R,Borgundvaag B,McIntyre M,Thwaites C,Ragan K,Wyllie A

更新日期：2014-11-01 00:00:00

abstract：:Calcium channel blockers, nitrates, and beta blockers are the primary agents used for the treatment of angina. Calcium has a central role in excitation-contraction, action potential generation, and ischemic cell death. The three currently available calcium antagonists are nifedipine, verapamil, and diltiazem. Second-g...

journal_title：Pharmacotherapy

authors： Angaran D

更新日期：1987-01-01 00:00:00

abstract：STUDY OBJECTIVES:To develop and validate a self-assessment adherence tool for imatinib in patients with chronic myeloid leukemia (CML), and to correlate the use of this tool with response to treatment and adverse effects. DESIGN:Retrospective cohort study. SETTING:Regional cancer center in France. PATIENTS:Forty-six...

journal_title：Pharmacotherapy

authors： Daouphars M,Ouvry M,Lenain P,Rouvet J,Jardin F,Bubenheim M,Varin R

更新日期：2013-02-01 00:00:00

abstract：OBJECTIVE:To review the literature on clonidine, venlafaxine, selective serotonin reuptake inhibitors, and gabapentin for the treatment of hot flashes. DATA SOURCES:A MEDLINE search (January 1966-July 2003) was conducted to identify English-language literature available on the treatment of hot flashes that focused on ...

journal_title：Pharmacotherapy

authors： Sicat BL,Brokaw DK

更新日期：2004-01-01 00:00:00

abstract：:Two analyses were conducted to compare the cost-effectiveness of different intravenous immunoglobulin (IGIV) formulations: IGIV purified by caprylate precipitation and chromatography (IGIV-C) and IGIV manufactured by an older solvent-detergent method (IGIV-S/D). The results indicated that IGIV-C is associated with cos...

journal_title：Pharmacotherapy

authors： Mahadevia PJ

更新日期：2005-11-01 00:00:00

abstract：:Diazepam is frequently the subject of review by various agencies and institutions charged with determining whether or not to substitute another, more economical drug--in most instances, chlordiazepoxide. A review of the comparative literature has shown that, on clinical and pharmacokinetic grounds, chlordiazepoxide is...

journal_title：Pharmacotherapy

authors： Baskin SI,Esdale A

更新日期：1982-03-01 00:00:00

abstract：STUDY OBJECTIVE:To evaluate the efficacy and safety of a new combination product, enalapril-diltiazem ER, when administered over the long term. DESIGN:Open-label, titration to response, with treatment lasting 46 weeks after a 6-week, double-blind phase. SETTING:Medical clinics in the private and academic sectors. PA...

journal_title：Pharmacotherapy

authors： Applegate W,Cohen JD,Wolfson P,Davis A,Green S

更新日期：1997-01-01 00:00:00

abstract：STUDY OBJECTIVE:To determine the usage patterns of the lipid-based amphotericin B formulations at our institution and to compare the observed nephrotoxicity and efficacy of these formulations. DESIGN:Prospective and retrospective observational study SETTING:Urban 350-bed teaching hospital. PATIENTS:Sixty-seven nonhe...

journal_title：Pharmacotherapy

authors： Cannon JP,Garey KW,Danziger LH

更新日期：2001-09-01 00:00:00

abstract：:We examined whether low doses of phenytoin, which should be associated with few dose-related side effects, may increase the levels of high-density lipoprotein (HDL) cholesterol. Of 35 healthy adult men who consented to participate, 31 completed the study. They took no medications and consumed no alcohol during the stu...

journal_title：Pharmacotherapy

authors： McKenney JM,Petrizzi KS,Briggs GC,Wright JT Jr

更新日期：1992-01-01 00:00:00

abstract：:Recombinant human erythropoietin reverses the severe anemia associated with end-stage renal disease. Mean half-life values after a single intravenous bolus dose range from 4-13 hours. Renal clearance is not a significant route of elimination. Dosing schedules in chronic renal failure involve a single intravenous bolus...

journal_title：Pharmacotherapy

authors： Flaharty KK

更新日期：1990-03-01 00:00:00

abstract：:A 40-year-old Caucasian man diagnosed with right deep venous thrombosis secondary to trauma was treated with subcutaneous enoxaparin. Within minutes of administering the first dose (1 mg/kg), he experienced an apparent anaphylactoid reaction; symptoms were abdominal pruritus, severe cough, shortness of breath, anxiety...

journal_title：Pharmacotherapy

authors： MacLaughlin EJ,Fitzpatrick KT,Sbar E,Jewell C

更新日期：2002-11-01 00:00:00

abstract：:The objective of this study was to describe the postinduction clearance of carbamazepine (CBZ) in adult psychiatric patients by population pharmacokinetic analysis using the NONMEM program. Specifically, an estimate of CBZ clearance and insight into the effect of common patient characteristics on clearance were sought...

journal_title：Pharmacotherapy

authors： Martin ES 3rd,Crismon ML,Godley PJ

更新日期：1991-01-01 00:00:00

abstract：:Meglumine antimoniate was administered to a patient with visceral leishmaniasis with normal renal function. Soon after the first intramuscular administration of meglumine antimoniate 20 mg/kg, equivalent to 510 mg antimony (Sb), the patient developed septic shock with oliguria. Creatinine clearance decreased to 23 ml/...

journal_title：Pharmacotherapy

authors： Hantson P,Luyasu S,Haufroid V,Lambert M

更新日期：2000-09-01 00:00:00

abstract：:Conditions in which antidepressants have been used include diabetic neuropathy, postherpetic neuralgia, headaches, arthritis, chronic back pain, cancer, thalamic pain, facial pain, and phantom limb pain. Although much of the available information is derived from inadequately controlled trials, it seems that antidepres...

journal_title：Pharmacotherapy

authors： Egbunike IG,Chaffee BJ

更新日期：1990-01-01 00:00:00

abstract：OBJECTIVE:To evaluate the effect of telephone follow-up on the physical well-being dimension of health-related quality of life in patients with cancer. DESIGN:Randomized, controlled trial. SETTING:Public teaching hospital. PATIENTS:One hundred fifty patients with cancer who were discharged to home from the hospital....

journal_title：Pharmacotherapy

authors： Beney J,Devine EB,Chow V,Ignoffo RJ,Mitsunaga L,Shahkarami M,McMillan A,Bero LA

更新日期：2002-10-01 00:00:00

abstract：:Clopidogrel decreases the morbidity and mortality associated with several cardiovascular diseases. However, clopidogrel is a prodrug that needs to be metabolized to the active thiol metabolite by the cytochrome P450 (CYP) system. This activation is a source of significant interindividual variability in clopidogrel res...

journal_title：Pharmacotherapy

authors： Momary KM,Dorsch MP,Bates ER

更新日期：2010-03-01 00:00:00

abstract：:Thrombin, a serine protease, is the keystone of the twin processes of hemostasis and thrombosis. Through procoagulant, anticoagulant, and antifibrinolytic mechanisms, thrombin helps maintain vascular integrity in the face of hemorrhage. These same mechanisms, however, allow for the pathologic formation of thrombi in r...

journal_title：Pharmacotherapy

authors： Nappi J

更新日期：2002-06-01 00:00:00

abstract：STUDY OBJECTIVES:To determine the incidence of Clostridium difficile infection (CDI) at one community hospital by identifying patients with stool samples positive for C. difficile toxin A or B, and to compare the incidence with a 2008 national estimate; and to determine which patient characteristics and concomitant ant...

journal_title：Pharmacotherapy

authors： King RN,Lager SL

更新日期：2011-07-01 00:00:00

abstract：:The use of angiotensin-converting enzyme (ACE) inhibitors and angiotensin receptor blockers (ARBs) has significantly reduced morbidity and mortality across the continuum of vascular disease. The utilization of these agents, however, remains suboptimal. The drugs are not prescribed in many patients because of concerns ...

journal_title：Pharmacotherapy

authors： Epstein BJ

更新日期：2004-05-01 00:00:00

abstract：:Human herpesvirus infections continue to be a concern in immunocompetent as well as immunocompromised hosts. They are often life threatening in the immunocompromised patient. In the healthy immunocompetent person the infections tend to be self-limited, although they can directly or indirectly cause periods of severe d...

journal_title：Pharmacotherapy

authors： Dudley MN

更新日期：1995-09-01 00:00:00

abstract：:Ischemic stroke is a prevalent disease with a large burden on the health system. Preventive strategies, therefore, are paramount. Primary prevention is aimed at reducing the risk of stroke in asymptomatic people. The most effective prevention is through control of modifiable risk factors. Due to the large amount of li...

journal_title：Pharmacotherapy

authors： Baker WL,Marrs JC,Davis LE,Nutescu EA,Rowe AS,Ryan M,Splinter MY,Vardeny O,Fagan SC

更新日期：2013-06-01 00:00:00

abstract：:Clinical trials continue to evaluate the pharmacologic management of myocardial infarction for benefits in mortality, degree of infarct artery patency, and frequency of reocclusion. The discovery of thrombus formation in the development of the myocardial infarction renewed interest in thrombolytic therapy. In appropri...

journal_title：Pharmacotherapy

authors： Talbert RL

更新日期：1996-09-01 00:00:00

abstract：:Apixaban, a direct factor Xa inhibitor, is a novel oral anticoagulant (NOAC) indicated for prevention of embolic events in patients with nonvalvular atrial fibrillation. The agent is associated with a lower risk of bleeding compared with vitamin K antagonists such as warfarin. Hemopericardium is a life-threatening ble...

journal_title：Pharmacotherapy

authors： Sigawy C,Apter S,Vine J,Grossman E

更新日期：2015-07-01 00:00:00