Evaluation of the reproducibility of the Naranjo Adverse Drug Reaction Probability Scale score in published case reports.

abstract：:Conditions in which antidepressants have been used include diabetic neuropathy, postherpetic neuralgia, headaches, arthritis, chronic back pain, cancer, thalamic pain, facial pain, and phantom limb pain. Although much of the available information is derived from inadequately controlled trials, it seems that antidepres...

journal_title：Pharmacotherapy

authors： Egbunike IG,Chaffee BJ

更新日期：1990-01-01 00:00:00

abstract：:Warfarin, a vitamin K antagonist, has been the only orally available anticoagulant for > 60 years. During the past decade, the U.S. Food and Drug Administration has approved several target-specific oral anticoagulants (TSOACs) for the prophylaxis and treatment of arterial and venous thromboembolism and stroke preventi...

journal_title：Pharmacotherapy

authors： Mo Y,Yam FK

更新日期：2015-02-01 00:00:00

abstract：STUDY OBJECTIVE:To evaluate the effectiveness, safety, and costs associated with a formulary conversion from amlodipine to alternative calcium channel blockers. DESIGN:Retrospective study. SETTING:Veterans Affairs Medical Center. PATIENTS:One hundred patients with hypertension who were receiving amlodipine. INTERVE...

journal_title：Pharmacotherapy

authors： Parra D,Beckey NP,Korman L

更新日期：2000-09-01 00:00:00

abstract：:Mitochondrial myopathy, encephalopathy, lactic acidosis, and stroke-like episodes (MELAS) syndrome is a rare neurodegenerative disease caused by the decreased ability of cells to produce sufficient energy in the form of adenosine 5'-triphosphate. Although it is one of the most common maternally inherited mitochondrial...

journal_title：Pharmacotherapy

authors： Santa KM

更新日期：2010-11-01 00:00:00

abstract：:Patients undergoing cardiopulmonary bypass may develop clinically significant physiologic alterations in the perioperative period, including alteration of thyroid hormone concentrations. Alterations in the concentration of thyroid hormones are of concern due to the effects of these hormones on cardiac function. Hypoth...

journal_title：Pharmacotherapy

authors： Reichert MG,Verzino KC

更新日期：2001-11-01 00:00:00

abstract：:Intravenous unfractionated heparin (UFH) remains an important therapeutic agent, particularly in the inpatient setting, for anticoagulation. Historically, the activated partial thromboplastin time (aPTT) has been the primary laboratory test used to monitor and adjust UFH. The aPTT test has evolved since the 1950s, and...

journal_title：Pharmacotherapy

authors： Vandiver JW,Vondracek TG

更新日期：2012-06-01 00:00:00

abstract：:Acute respiratory distress syndrome (ARDS) is an acute inflammatory process that impairs the ability of the lungs to oxygenate and ultimately leads to respiratory failure. Patients who develop ARDS often have prolonged and complicated hospital courses putting them at risk for intensive care unit (ICU) delirium. Patien...

journal_title：Pharmacotherapy

authors： Torbic H,Duggal A

更新日期：2018-04-01 00:00:00

abstract：:Agitation in the elderly, manifested by verbal and physical aggression, frequently results in increased morbidity and mortality for nursing home residents and reduced morale for the family and nursing home staff. It is also responsible for increased costs associated with caring for these residents. Pharmacologic inter...

journal_title：Pharmacotherapy

authors： Grossman F

更新日期：1998-05-01 00:00:00

abstract：:Our objective was to describe the implementation and clinical outcomes of an employer-sponsored, pharmacist-provided medication therapy management (MTM) program for health plan beneficiaries with diabetes mellitus and/or hypertension. We conducted a single-center retrospective medical record review. The setting was a ...

journal_title：Pharmacotherapy

authors： Theising KM,Fritschle TL,Scholfield AM,Hicks EL,Schymik ML

更新日期：2015-11-01 00:00:00

abstract：:The purpose of the American College of Clinical Pharmacy (ACCP) is to advance human health by extending the frontiers of clinical pharmacy. Consistent with this mission and its core values, ACCP is committed to ensuring that clinical pharmacists possess the knowledge, skills, attitudes, and behaviors necessary to deli...

journal_title：Pharmacotherapy

authors： Saseen JJ,Ripley TL,Bondi D,Burke JM,Cohen LJ,McBane S,McConnell KJ,Sackey B,Sanoski C,Simonyan A,Taylor J,Vande Griend JP

更新日期：2017-05-01 00:00:00

abstract：:In critically ill patients with acute renal failure, continuous arteriovenous hemodiafiltration (CAVHD) has become an increasing popular supportive technique. An adult with acute renal failure during CAVHD therapy received fluconazole. Drug clearance by the hemodiafilter system and its total body clearance during the ...

journal_title：Pharmacotherapy

authors： Nicolau DP,Crowe H,Nightingale CH,Quintiliani R

更新日期：1994-07-01 00:00:00

abstract：:Ziconotide intrathecal infusion was recently approved by the United States Food and Drug Administration for the treatment of intractable severe chronic pain. Patients with neuropathic pain make up a significant population among those who experience chronic pain for which there are less than optimal pharmacotherapeutic...

journal_title：Pharmacotherapy

authors： Wermeling DP,Berger JR

更新日期：2006-03-01 00:00:00

abstract：STUDY OBJECTIVES:To evaluate the safety and efficacy of aerosolized ceftazidime for prevention of ventilator-associated pneumonia (VAP) and to evaluate the effects of the drug on the proinflammatory response. DESIGN:Prospective, randomized, double-blind, placebo-controlled clinical trial. SETTING:University teaching ...

journal_title：Pharmacotherapy

authors： Wood GC,Boucher BA,Croce MA,Hanes SD,Herring VL,Fabian TC

更新日期：2002-08-01 00:00:00

abstract：:Females of childbearing age represent a large population of solid organ transplant recipients. With fertility commonly restored after transplantation, the possibility of pregnancy becomes a reality for many patients. Since the first published report of a successful pregnancy after solid organ transplantation in 1963, ...

journal_title：Pharmacotherapy

authors： Casale JP,Doligalski CT

更新日期：2016-09-01 00:00:00

abstract：:Methicillin-susceptible Staphylococcus aureus (MSSA) bacteremia is associated with high morbidity and mortality. Traditionally, antistaphylococcal penicillins (ASPs) have been considered the agents of choice for the treatment of MSSA bacteremia. Vancomycin has been demonstrated to have poorer outcomes in several studi...

journal_title：Pharmacotherapy

authors： Li J,Echevarria KL,Traugott KA

更新日期：2017-03-01 00:00:00

abstract：:Cytochrome P450 3A5 (CYP3A5) and cytochrome P450 3A4 (CYP3A4) are the predominate enzymes responsible for tacrolimus metabolism. The presence of CYP3A4 and CYP3A5 genetic variants significantly affects tacrolimus clearance and dose requirements. CYP3A5*3 is a loss-of-function variant resulting in no CYP3A5 enzyme prod...

journal_title：Pharmacotherapy

authors： Scheibner A,Remmel R,Schladt D,Oetting WS,Guan W,Wu B,Dorr C,Israni A,Jacobson PA

更新日期：2018-07-01 00:00:00

abstract：:Patients with various rheumatologic and inflammatory disease states commonly require drugs known to decrease the inflammatory or autoimmune response for adequate control of their condition. Such drugs include nonsteroidal antiinflammatory drugs (NSAIDs), cyclooxygenase (COX)-2 inhibitors, corticosteroids, disease-modi...

journal_title：Pharmacotherapy

authors： Busti AJ,Hooper JS,Amaya CJ,Kazi S

更新日期：2005-11-01 00:00:00

abstract：:The field of acid suppression has been advanced by therapeutics of increasing specificity for inhibiting gastric acid secretion. Particularly important are proton pump inhibitors (PPIs), which inhibit the activity of the gastric acid pump (H+,K(+)-adenosine triphosphatase), the final common step in gastric acid produc...

journal_title：Pharmacotherapy

authors： Sachs G

更新日期：2003-10-01 00:00:00

abstract：OBJECTIVE:To identify and describe the scope of practice that characterizes the critical care pharmacist and critical care pharmacy services. Specifically, the goals were to define the level of clinical practice and specialized skills characterizing the critical care pharmacist as clinician, educator, researcher, and m...

journal_title：Pharmacotherapy

authors：

更新日期：2000-11-01 00:00:00

abstract：:During the past decade, patient safety issues during care transitions have gained greater attention at both the local and national level. Readmission rates to U.S. hospitals are high, often because of poor care transitions. Serious adverse drug events (ADEs) caused by an incomplete understanding of changes in complex ...

journal_title：Pharmacotherapy

authors： American College of Clinical Pharmacy.,Hume AL,Kirwin J,Bieber HL,Couchenour RL,Hall DL,Kennedy AK,LaPointe NM,Burkhardt CD,Schilli K,Seaton T,Trujillo J,Wiggins B

更新日期：2012-11-01 00:00:00

abstract：:A 71-year-old Caucasian woman was admitted to the hospital with right-sided weakness and slurred speech. Glioblastoma multiforme was diagnosed, and resection of the tumor was performed. During the patient's hospitalization, blood and urine cultures were obtained after her temperature rose to 103.3 degrees F. Four bloo...

journal_title：Pharmacotherapy

authors： Pound MW,Fulton KB,Chima CO

更新日期：2007-01-01 00:00:00

abstract：:Verapamil hydrochloride, a prototype calcium antagonist, is now marketed in the United States for the acute treatment of supraventricular tachyarrhythmias and for chronic management of vasospastic and chronic stable angina. It inhibits the slow inward channel in in the heart and blocks calcium influx in smooth muscle....

journal_title：Pharmacotherapy

authors： Baky SH,Singh BN

更新日期：1982-11-01 00:00:00

abstract：STUDY OBJECTIVE:To determine the feasibility of therapeutic drug monitoring for adjusting low serum antimycobacterial concentrations in patients with both tuberculosis and advanced human immunodeficiency virus (HIV). DESIGN:Retrospective cohort study. DATA SOURCE:De-identified dataset from a tuberculosis clinic. PAT...

journal_title：Pharmacotherapy

authors： Holland DP,Hamilton CD,Weintrob AC,Engemann JJ,Fortenberry ER,Peloquin CA,Stout JE

更新日期：2009-05-01 00:00:00

abstract：:Recent literature has demonstrated significant improvements in neurologic outcomes in patients who have received induced hypothermia in the setting of out-of-hospital cardiac arrest. Through multiple metabolic mechanisms, the induction of hypothermia slows the progression and devastation of transient cerebral hypoxia....

journal_title：Pharmacotherapy

authors： Weant KA,Martin JE,Humphries RL,Cook AM

更新日期：2010-08-01 00:00:00

abstract：:Recombinant human erythropoietin reverses the severe anemia associated with end-stage renal disease. Mean half-life values after a single intravenous bolus dose range from 4-13 hours. Renal clearance is not a significant route of elimination. Dosing schedules in chronic renal failure involve a single intravenous bolus...

journal_title：Pharmacotherapy

authors： Flaharty KK

更新日期：1990-03-01 00:00:00

abstract：:Nausea and vomiting, common symptoms during pregnancy, often are regarded as an unpleasant but normal part of pregnancy during the first and early second trimesters. Nausea and vomiting of pregnancy (NVP) occurs in approximately 75-80% of pregnant women. The exact etiology and pathogenesis of NVP are poorly understood...

journal_title：Pharmacotherapy

authors： Badell ML,Ramin SM,Smith JA

更新日期：2006-09-01 00:00:00

abstract：STUDY OBJECTIVE:To assess the pharmacokinetic profile of palifermin after intravenous dosing with either a collapsed dose of 180 microg/kg/day for 1 day or a standard dose of 60 microg/kg/day for 3 days, before and after myeloablative chemoradiotherapy and peripheral blood progenitor cell (PBPC) transplantation. DESIG...

journal_title：Pharmacotherapy

authors： Zia-Amirhosseini P,Hurd DD,Salfi M,Cheah TC,Aycock J,Cesano A

更新日期：2007-10-01 00:00:00

abstract：STUDY OBJECTIVE:To compare the annual cost of proton pump inhibitors (PPIs) in the United States and in the United Kingdom. DESIGN:Matched-cohort cost analysis. DATA SOURCES:U.K. General Practice Research Database (GPRD) and MarketScan Commercial Claims and Encounter Database, a large, U.S. self-insured medical claim...

journal_title：Pharmacotherapy

authors： Jick H,Wilson A,Wiggins P,Chamberlain DP

更新日期：2012-06-01 00:00:00

abstract：:Polypharmacy has been found to have potentially negative consequences for patients due to use of potentially inappropriate medications, as well as increased risk of drug interactions and adverse effects. Deprescribing has been proposed as a method of improving medication use throughout a patient's course of care. This...

journal_title：Pharmacotherapy

authors： Bemben NM

更新日期：2016-07-01 00:00:00

abstract：:The use of angiotensin-converting enzyme (ACE) inhibitors and angiotensin receptor blockers (ARBs) has significantly reduced morbidity and mortality across the continuum of vascular disease. The utilization of these agents, however, remains suboptimal. The drugs are not prescribed in many patients because of concerns ...

journal_title：Pharmacotherapy

authors： Epstein BJ

更新日期：2004-05-01 00:00:00