Clinical decision rules in rheumatoid arthritis: do they identify patients at high risk for osteoporosis? Testing clinical criteria in a population based cohort of patients with rheumatoid arthritis recruited from the Oslo Rheumatoid Arthritis Register.

abstract：OBJECTIVE:To evaluate the effects of infliximab and corticosteroid treatment on the lipid profile in patients with active rheumatoid arthritis (RA). METHODS:Infliximab infusions were given at weeks 0, 2, 6 and then every 8 weeks. Before each infusion, disease activity parameters (Disease Activity Index 28-Joint Score ...

journal_title：Annals of the rheumatic diseases

authors： Peters MJ,Vis M,van Halm VP,Wolbink GJ,Voskuyl AE,Lems WF,Dijkmans BA,Twisk JW,de Koning MH,van de Stadt RJ,Nurmohamed MT

更新日期：2007-07-01 00:00:00

abstract：OBJECTIVES:To investigate whether anti-Saccharomyces cerevisiae antibodies (ASCA), a marker for Crohn's disease (CD), are present in spondyloarthropathies (SpA) and in the subgroups ankylosing spondylitis (AS), undifferentiated SpA (uSpA), and psoriatic arthritis (PsA), in comparison with healthy and inflammatory contr...

journal_title：Annals of the rheumatic diseases

authors： Hoffman IE,Demetter P,Peeters M,De Vos M,Mielants H,Veys EM,De Keyser F

更新日期：2003-05-01 00:00:00

abstract：BACKGROUND:An association between major histocompatibility complex (MHC) genes, particularly those within the class II HLA region, and rheumatoid arthritis (RA) is well established, and accounts for an estimated 30% of the genetic component in RA. The MHC class II transactivator gene (MHC2TA) on chromosome 16p13 has re...

journal_title：Annals of the rheumatic diseases

authors： Bronson PG,Criswell LA,Barcellos LF

更新日期：2008-07-01 00:00:00

abstract：OBJECTIVE:To evaluate the efficacy and safety of combining monthly intravenous methotrexate (IV MTX) with monthly IV cyclophosphamide (CYTX; given on the same day) for the treatment of children who develop recurrent diffuse proliferative glomerulonephritis secondary to systemic lupus erythematosus during or after the s...

journal_title：Annals of the rheumatic diseases

authors： Lehman TJ,Edelheit BS,Onel KB

更新日期：2004-03-01 00:00:00

abstract：:A 17-year-old female patient with systemic lupus erythematosus (SLE) developed chronic tophaceous gout, chondrocalcinosis and articular capsule calcification in several joints. Analysis of synovial fluid and tophi revealed the coexistence of monosodium urate, calcium pyrophosphate, hydroxyapatite, and cholesterol crys...

journal_title：Annals of the rheumatic diseases

authors： Rodríguez MA,Paul H,Abadí I,Bravo JR,Armas P

更新日期：1984-06-01 00:00:00

abstract：:T cells from patients with systemic lupus erythematosus exhibit a notable array of defects that probably contribute to the origin and development of the disease. Such abnormalities include an abnormal response to stimulation, aberrant expression of molecules that play key roles in intracellular signalling pathways, al...

journal_title：Annals of the rheumatic diseases

authors： Crispín JC,Kyttaris V,Juang YT,Tsokos GC

更新日期：2007-11-01 00:00:00

abstract：:Patients who develop reactive arthritis after yersinia enteritis are characterised by high and persisting IgA-anti-yersinia antibodies. We have further analysed the humoral immune response to yersinia in this condition. Total concentrations of IgM, IgG, IgA, and secretory IgA in the serum and specific anti-yersinia an...

journal_title：Annals of the rheumatic diseases

authors： Granfors K,Toivanen A

更新日期：1986-07-01 00:00:00

abstract：:The systemic vasculitides are multisystem disorders with considerable mortality and morbidity and frequent relapses. In the absence of reliable serological markers, accurate clinical tools are required to assess disease activity and damage for treatment decisions, and for the performance of clinical trials. This artic...

journal_title：Annals of the rheumatic diseases

authors： Flossmann O,Bacon P,de Groot K,Jayne D,Rasmussen N,Seo P,Westman K,Luqmani R

更新日期：2007-03-01 00:00:00

abstract：OBJECTIVE:To assess the safety and effectiveness of imatinib mesylate in the treatment of diffuse cutaneous systemic sclerosis (dcSSc). METHODS:In this phase IIa, open-label, single-arm clinical trial, 30 patients with dcSSc were treated with imatinib 400 mg daily. Patients were monitored monthly for safety assessment...

journal_title：Annals of the rheumatic diseases

authors： Spiera RF,Gordon JK,Mersten JN,Magro CM,Mehta M,Wildman HF,Kloiber S,Kirou KA,Lyman S,Crow MK

更新日期：2011-06-01 00:00:00

abstract：OBJECTIVES:Previous evidence suggests the role of psychological stress in triggering the onset of autoimmunity. We aimed to investigate whether stress following major and minor life events could precede the onset of primary Sjögren's syndrome (pSS). The role of coping strategies and social support, as compensating buff...

journal_title：Annals of the rheumatic diseases

authors： Karaiskos D,Mavragani CP,Makaroni S,Zinzaras E,Voulgarelis M,Rabavilas A,Moutsopoulos HM

更新日期：2009-01-01 00:00:00

abstract：BACKGROUND:Increased subchondral bone turnover may contribute to pain in osteoarthritis (OA). OBJECTIVES:To investigate the analgesic potential of a modified version of osteoprotegerin (osteoprotegerin-Fc (OPG-Fc)) in the monosodium iodoacetate (MIA) model of OA pain. METHODS:Male Sprague Dawley rats (140-260 g) were...

journal_title：Annals of the rheumatic diseases

authors： Sagar DR,Ashraf S,Xu L,Burston JJ,Menhinick MR,Poulter CL,Bennett AJ,Walsh DA,Chapman V

更新日期：2014-08-01 00:00:00

abstract：:To establish the prevalence of inflammatory bowel disease in ankylosing spondylitis (AS), 79 AS patients underwent detailed medical screening, including sigmoidoscopic and roentgenological examination, 48 had gastrointestinal symptoms and the others did not. In 3 patients a diagnosis of Crohn's disease was made which ...

journal_title：Annals of the rheumatic diseases

authors： Meuwissen SG,Dekker-Saeys BJ,Agenant D,Tytgat GN

更新日期：1978-02-01 00:00:00

abstract：OBJECTIVES:To assess the reliability of the OMERACT ultrasound (US) definitions for the identification of calcium pyrophosphate deposition disease (CPPD) at the metacarpal-phalangeal, triangular fibrocartilage of the wrist (TFC), acromioclavicular (AC) and hip joints. METHODS:A web-based exercise and subsequent patien...

journal_title：Annals of the rheumatic diseases

authors： Filippou G,Scirè CA,Adinolfi A,Damjanov NS,Carrara G,Bruyn GAW,Cazenave T,D'Agostino MA,Delle Sedie A,Di Sabatino V,Diaz Cortes ME,Filippucci E,Gandjbakhch F,Gutierrez M,Maccarter DK,Micu M,Möller Parera I,Mouterde G,

更新日期：2018-08-01 00:00:00

abstract：:A family is described in which the mother and 2 of the 5 children had Felty's syndrome, a pattern of inheritance suggesting a dominant defect and one which has not previously been reported. The family is also of interest in that the other sib had rheumatoid arthritis. ...

journal_title：Annals of the rheumatic diseases

authors： Blendis LM,Jones KL,Hamilton EB,Williams R

更新日期：1976-06-01 00:00:00

abstract：:Published case reports of chloroquine retinopathy rarely include details of daily dosage, but 30 reports where this information was available included 78 patients who developed impaired visual acuity an 13 had received daily doses of 250 mg or less. Eleven cases of ocular toxicity attributed to chloroquine were report...

journal_title：Annals of the rheumatic diseases

authors： Marks JS

更新日期：1982-02-01 00:00:00

abstract：OBJECTIVE:To determine, using the method of adjusted indirect comparisons, whether there are differences in efficacy of tumour necrosis factor (TNF alpha) blocking agents, as measured by the rate ratios for American College of Rheumatology (ACR) 20, 50, and 70 responses, in patients with rheumatoid arthritis with an in...

journal_title：Annals of the rheumatic diseases

authors： Hochberg MC,Tracy JK,Hawkins-Holt M,Flores RH

更新日期：2003-11-01 00:00:00

abstract：OBJECTIVE:To elucidate factors involved in the arthritogenicity of bacterial cell walls. METHODS:For characterisation of an arthritogenic Eubacterium aerofaciens cell wall, peptidoglycan-polysaccharide (PG-PS) polymers were isolated by removing cell wall associated proteins (CWPs), PG and PS moieties were separated, a...

journal_title：Annals of the rheumatic diseases

authors： Zhang X,Rimpiläinen M,Simelyte E,Toivanen P

更新日期：2001-03-01 00:00:00

abstract：OBJECTIVE:To investigate the membrane expression of the 52 kDa Ro(SS-A) and La(SS-B) antigens in human keratinocytes under the influence of an important mediator of inflammation, TNF alpha. METHODS:Keratinocytes, isolated from human skins obtained at circumcision and identified using monoclonal antibodies, were treate...

journal_title：Annals of the rheumatic diseases

authors： Dörner T,Hucko M,Mayet WJ,Trefzer U,Burmester GR,Hiepe F

更新日期：1995-11-01 00:00:00

abstract：OBJECTIVE:To evaluate the ability of ultrasound (US) to detect the presence and change of Achilles erosions in spondyloarthritis (SpA). METHODS:A blind prospective two-dimensional (2D) and three-dimensional (3D) US study of Achilles enthesis erosions in early SpA was undertaken. US examinations were performed at basel...

journal_title：Annals of the rheumatic diseases

authors： de Miguel E,Falcao S,Castillo C,Plasencia C,García M,Branco JC,Martín-Mola E

更新日期：2011-11-01 00:00:00

abstract：OBJECTIVE:Anticitrullinated protein antibodies (ACPA) are the most predictive factor for the development of rheumatoid arthritis (RA). Epitope spreading towards more citrullinated epitopes occurs before the onset of RA. Here, the authors investigated whether specific epitope recognition allows the identification of spe...

journal_title：Annals of the rheumatic diseases

authors： Willemze A,Böhringer S,Knevel R,Levarht EW,Stoeken-Rijsbergen G,Houwing-Duistermaat JJ,van der Helm-van Mil AH,Huizinga TW,Toes RE,Trouw LA

更新日期：2012-02-01 00:00:00

abstract：OBJECTIVE:To compare individually tailored, based on trimestrial biological parameter monitoring, to fixed-schedule rituximab reinfusion for remission maintenance of antineutrophil cytoplasm antibody (ANCA)-associated vasculitides (AAVs). METHODS:Patients with newly diagnosed or relapsing granulomatosis with polyangii...

journal_title：Annals of the rheumatic diseases

authors： Charles P,Terrier B,Perrodeau É,Cohen P,Faguer S,Huart A,Hamidou M,Agard C,Bonnotte B,Samson M,Karras A,Jourde-Chiche N,Lifermann F,Gobert P,Hanrotel-Saliou C,Godmer P,Martin-Silva N,Pugnet G,Matignon M,Aumaitre O,

更新日期：2018-08-01 00:00:00

abstract：OBJECTIVE:To investigate the role of the HS1,2 enhancer polymorphisms as a new candidate marker for rheumatoid arthritis (RA) and to define the possible association with autoantibody positivity and clinical outcome. METHODS:Genomic DNA was obtained from two cohorts of patients with RA (100 with early RA (ERA) and 114 ...

journal_title：Annals of the rheumatic diseases

authors： Tolusso B,Frezza D,Mattioli C,Fedele AL,Bosello S,Faustini F,Peluso G,Giambra V,Pietrapertosa D,Morelli A,Gremese E,De Santis M,Ferraccioli GF

更新日期：2009-03-01 00:00:00

abstract：:Two animal models were used to investigate the mode of action of levamisole and thymopoietin. Neither compound influenced the subcutaneous carrageenan air pouch. While thymopoietin inhibited the formation of cotton pellet granulomas, levamisole enhanced it. This supports the conclusions of clinical studies reported el...

journal_title：Annals of the rheumatic diseases

authors： Thrower PA,Sedgwick AD,Smith ER,Willoughby DA,Huskisson EC

更新日期：1983-02-01 00:00:00

abstract：OBJECTIVES:To investigate whether bortezomib, a proteasome inhibitor approved for treatment of multiple myeloma, induces clinically relevant plasma cell (PC) depletion in patients with active, refractory systemic lupus erythematosus (SLE). METHODS:Twelve patients received a median of two (range 1-4) 21-day cycles of i...

journal_title：Annals of the rheumatic diseases

authors： Alexander T,Sarfert R,Klotsche J,Kühl AA,Rubbert-Roth A,Lorenz HM,Rech J,Hoyer BF,Cheng Q,Waka A,Taddeo A,Wiesener M,Schett G,Burmester GR,Radbruch A,Hiepe F,Voll RE

更新日期：2015-07-01 00:00:00

abstract：OBJECTIVES:To study the reliability and construct validity of ultrasound in interphalangeal finger joints affected by erosive osteoarthritis (EOA) and non-EOA with MRI as the reference method. METHODS:252 joints were examined by ultrasound, conventional radiography and clinical examination. Ultrasound was performed us...

journal_title：Annals of the rheumatic diseases

authors： Wittoek R,Jans L,Lambrecht V,Carron P,Verstraete K,Verbruggen G

更新日期：2011-02-01 00:00:00

abstract：OBJECTIVE:To compare two plain radiographic methods for sensitivity to detect progression of patellofemoral osteoarthritis. METHODS:Two sets of paired skyline and lateral knee radiographs from 54 hospital referred patients (108 knees) with knee osteoarthritis were taken an average of 31 months apart (range 12-40). Fil...

journal_title：Annals of the rheumatic diseases

authors： Lanyon P,Jones A,Doherty M

更新日期：1996-12-01 00:00:00

abstract：:There is no agreement as to which variable best mirrors disease activity in rheumatoid arthritis (RA) and no studies have been performed on the validity of disease activity variables. In this study the validity of 10 commonly used single variables and three composite indices was tested. All patients participated in a ...

journal_title：Annals of the rheumatic diseases

authors： van der Heijde DM,van't Hof MA,van Riel PL,van Leeuwen MA,van Rijswijk MH,van de Putte LB

更新日期：1992-02-01 00:00:00

abstract：BACKGROUND:Chondromalacia patellae is a potentially disabling disorder characterised by features of patellar cartilage degradation. OBJECTIVE:To evaluate markers of cartilage and bone turnover in patients with chondromalacia patellae. METHODS:18 patients with chondromalacia patellae were studied. Serum cartilage olig...

journal_title：Annals of the rheumatic diseases

authors： Murphy E,FitzGerald O,Saxne T,Bresnihan B

更新日期：2002-11-01 00:00:00

abstract：OBJECTIVE:To determine the frequency and suppressive capacity of regulatory T cells (T(reg)) and their association with clinical parameters in patients with systemic scleroderma (SSc). METHODS:Peripheral blood from 25 patients with SSc, 15 patients with localised scleroderma (LS) and 29 healthy controls (HC) was studi...

journal_title：Annals of the rheumatic diseases

authors： Klein S,Kretz CC,Ruland V,Stumpf C,Haust M,Hartschuh W,Hartmann M,Enk A,Suri-Payer E,Oberle N,Krammer PH,Kuhn A

更新日期：2011-08-01 00:00:00

abstract：OBJECTIVE:To systematically evaluate the association between MRI findings (cartilage defects, bone marrow lesions (BML), osteophytes, meniscal lesion, effusion/synovitis, ligamentous abnormalities, subchondral cysts and bone attrition) and pain in patients with knee osteoarthritis (OA) in order to establish the relevan...

journal_title：Annals of the rheumatic diseases

authors： Yusuf E,Kortekaas MC,Watt I,Huizinga TW,Kloppenburg M

更新日期：2011-01-01 00:00:00