Increased serum cartilage oligomeric matrix protein levels and decreased patellar bone mineral density in patients with chondromalacia patellae.

abstract：:We describe a case of systemic sclerosis with sympathetic and parasympathetic neuropathy and detail autonomic testing in six further patients. Of these six patients, three showed early parasympathetic damage. None of the patients had evidence of peripheral neuropathy, and there was no correlation between the presence ...

journal_title：Annals of the rheumatic diseases

authors： Sonnex C,Paice E,White AG

更新日期：1986-11-01 00:00:00

abstract：:To establish the prevalence of inflammatory bowel disease in ankylosing spondylitis (AS), 79 AS patients underwent detailed medical screening, including sigmoidoscopic and roentgenological examination, 48 had gastrointestinal symptoms and the others did not. In 3 patients a diagnosis of Crohn's disease was made which ...

journal_title：Annals of the rheumatic diseases

authors： Meuwissen SG,Dekker-Saeys BJ,Agenant D,Tytgat GN

更新日期：1978-02-01 00:00:00

abstract：:The relation between common rheumatic diseases such as osteoarthrosis, arthralgia without definite signs of osteoarthrosis, subacromial shoulder pain, different forms of tendinitis, low back pain and neck pain, and the level of formal education, occupational workload and some lifestyle factors were examined in 502 of ...

journal_title：Annals of the rheumatic diseases

authors： Jacobsson L,Lindgärde F,Manthorpe R,Ohlsson K

更新日期：1992-07-01 00:00:00

abstract：:This review assesses the risk assessment of cardiovascular disease (CVD) in rheumatoid arthritis (RA) and how non-invasive imaging modalities may improve risk stratification in future. RA is common and patients are at greater risk of CVD than the general population. Cardiovascular (CV) risk stratification is recommend...

journal_title：Annals of the rheumatic diseases

authors： Fent GJ,Greenwood JP,Plein S,Buch MH

更新日期：2017-07-01 00:00:00

abstract：OBJECTIVES:Recent animal studies have revealed critical roles of interleukin (IL)17, which is produced by a newly identified subset of helper T cells, Th17 cells, in the development of autoimmune diseases including arthritis. However, in human rheumatoid arthritis (RA), detailed characteristics and the prevalence of Th...

journal_title：Annals of the rheumatic diseases

authors： Yamada H,Nakashima Y,Okazaki K,Mawatari T,Fukushi JI,Kaibara N,Hori A,Iwamoto Y,Yoshikai Y

更新日期：2008-09-01 00:00:00

abstract：OBJECTIVE:Evidence was sought for genetic anticipation (disease occurring at an earlier age in subsequent generations, with increasing severity) in nodal osteoarthritis (NOA). METHODS:Age at symptom onset and disease severity was compared within 30 parent/offspring pairs with NOA. Correlation between the offspring age...

journal_title：Annals of the rheumatic diseases

authors： Wright GD,Regan M,Deighton CM,Wallis G,Doherty M

更新日期：1998-09-01 00:00:00

abstract：:Three hundred and twenty-one synovial fluids from the knees of patients with six different inflammatory arthropathies have been examined for the presence of cytophagocytic monocytes (CPM) and mast cells. Both cell types were seen independently in many of the fluids examined but were found together only in those patien...

journal_title：Annals of the rheumatic diseases

authors： Freemont AJ,Denton J

更新日期：1985-05-01 00:00:00

abstract：BACKGROUND:Osteoarthritis is the most frequent chronic joint disease causing pain and disability. Besides biomechanical mechanisms, the pathogenesis of osteoarthritis may involve inflammation, vascular alterations and dysregulation of lipid metabolism. As statins are able to modulate many of these processes, this study...

journal_title：Annals of the rheumatic diseases

authors： Clockaerts S,Van Osch GJ,Bastiaansen-Jenniskens YM,Verhaar JA,Van Glabbeek F,Van Meurs JB,Kerkhof HJ,Hofman A,Stricker BH,Bierma-Zeinstra SM

更新日期：2012-05-01 00:00:00

abstract：:A 60-year-old man with destructive rheumatoid disease, multiple nodules, and vasculitis developed a facial rash with ulceration and scarring. Histology showed granulomatous vasculitis. The rash was rapidly controlled with oral corticosteroids. Granulomatous vasculitis has not previously been reported as causing this c...

journal_title：Annals of the rheumatic diseases

authors： White R,Wegman A,Bulpitt P,Wood G,Fleming A

更新日期：1986-01-01 00:00:00

abstract：BACKGROUND:Human leucocyte antigen (HLA) genes predict disease severity in psoriasis (HLA-Cw6) and rheumatoid arthritis (shared epitope (SE)), but the situation is unclear for psoriatic arthritis (PsA). AIM:To determine the association of the HLA-Cw6 and HLA-DRB1 gene with disease severity in a large UK cohort with Ps...

journal_title：Annals of the rheumatic diseases

authors： Ho PY,Barton A,Worthington J,Thomson W,Silman AJ,Bruce IN

更新日期：2007-06-01 00:00:00

abstract：:Serum C2 activity was measured in 135 individuals drawn from a panel of 418 tissue-typed blood donors. The study group included all donors with HLA antigens A10 and B18. Heterozygote C2 deficiency (C2Dhet) was defined by reference to the range of C2 activity in previously studied obligate heterozygotes. Five donors we...

journal_title：Annals of the rheumatic diseases

authors： Rynes RI,Britten AF,Pickering RJ

更新日期：1982-02-01 00:00:00

abstract：OBJECTIVE:To compare three questions on knee pain with respect to determined prevalence and associations with disability and structural change. METHODS:Postal survey to 4057 men and women aged 40-79 years. Knee pain was defined by three questions: (A) "Have you ever had pain in or around the knee on most days for at l...

journal_title：Annals of the rheumatic diseases

authors： O'Reilly SC,Muir KR,Doherty M

更新日期：1996-12-01 00:00:00

abstract：:The capacity of monocytes from patients with rheumatoid arthritis to generate superoxide anion in vitro after stimulation with serum treated zymosan (STZ) or IgG treated zymosan (IgTZ) was studied before and during therapy with penicillamine (n = 9) or sodium aurothiomalate (AuTM) (n = 12). Significant increases in ra...

journal_title：Annals of the rheumatic diseases

authors： Hurst NP,Bell AL,Nuki G

更新日期：1986-01-01 00:00:00

abstract：OBJECTIVE:To evaluate the effects of infliximab and corticosteroid treatment on the lipid profile in patients with active rheumatoid arthritis (RA). METHODS:Infliximab infusions were given at weeks 0, 2, 6 and then every 8 weeks. Before each infusion, disease activity parameters (Disease Activity Index 28-Joint Score ...

journal_title：Annals of the rheumatic diseases

authors： Peters MJ,Vis M,van Halm VP,Wolbink GJ,Voskuyl AE,Lems WF,Dijkmans BA,Twisk JW,de Koning MH,van de Stadt RJ,Nurmohamed MT

更新日期：2007-07-01 00:00:00

abstract：BACKGROUND:Fractalkine expressed on endothelial cells mediates activation and adhesion of leucocytes expressing its receptor, CX(3)CR1. Soluble fractalkine exhibits chemotactic activity for leucocytes expressing CX(3)CR1. OBJECTIVE:To determine the role of fractalkine and its receptor in systemic sclerosis (SSc) by as...

journal_title：Annals of the rheumatic diseases

authors： Hasegawa M,Sato S,Echigo T,Hamaguchi Y,Yasui M,Takehara K

更新日期：2005-01-01 00:00:00

abstract：PURPOSE:To assess risk of cartilage loss in the tibiofemoral joint in relation to baseline damage severity, and to analyse the association of nearby pathologic findings on the risk of subsequent cartilage loss. METHODS:The Multicenter Osteoarthritis Study is a longitudinal study of individuals with or at high risk for...

journal_title：Annals of the rheumatic diseases

authors： Roemer FW,Felson DT,Wang K,Crema MD,Neogi T,Zhang Y,Nevitt MC,Marra MD,Lewis CE,Torner J,Guermazi A,MOST study investigators.

更新日期：2013-06-01 00:00:00

abstract：OBJECTIVE:To systematically evaluate the association between MRI findings (cartilage defects, bone marrow lesions (BML), osteophytes, meniscal lesion, effusion/synovitis, ligamentous abnormalities, subchondral cysts and bone attrition) and pain in patients with knee osteoarthritis (OA) in order to establish the relevan...

journal_title：Annals of the rheumatic diseases

authors： Yusuf E,Kortekaas MC,Watt I,Huizinga TW,Kloppenburg M

更新日期：2011-01-01 00:00:00

abstract：OBJECTIVES:(a) To characterise the lipid profile in psoriatic arthritis and investigate whether there are similarities to the dyslipoproteinaemia reported in rheumatoid arthritis and other inflammatory forms of joint disease; (b) to investigate whether there is an atherogenic lipid profile in psoriatic arthritis, which...

journal_title：Annals of the rheumatic diseases

authors： Jones SM,Harris CP,Lloyd J,Stirling CA,Reckless JP,McHugh NJ

更新日期：2000-11-01 00:00:00

abstract：OBJECTIVE:To review the presentation and clinical findings of arthritis associated with hidradenitis suppurativa. METHOD:Medical records from the rheumatology clinics of two major teaching hospitals were reviewed for arthritis and hidradenitis suppurativa. The nine patient records fulfilling these criteria were review...

journal_title：Annals of the rheumatic diseases

authors： Bhalla R,Sequeira W

更新日期：1994-01-01 00:00:00

abstract：OBJECTIVE:To elaborate a clinical practice decision tree for the choice of the first disease modifying antirheumatic drug (DMARD) for untreated rheumatoid arthritis of less than six months' duration. METHODS:Four steps were employed: (1) review of published reports on DMARD efficacy against rheumatoid arthritis; (2) i...

journal_title：Annals of the rheumatic diseases

authors： Le Loët X,Berthelot JM,Cantagrel A,Combe B,De Bandt M,Fautrel B,Flipo RM,Lioté F,Maillefert JF,Meyer O,Saraux A,Wendling D,Guillemin F

更新日期：2006-01-01 00:00:00

abstract：BACKGROUND:Aiming at therapeutic targets has reduced the risk of organ failure in many diseases such as diabetes or hypertension. Such targets have not been defined for rheumatoid arthritis (RA). OBJECTIVE:/st> To develop recommendations for achieving optimal therapeutic outcomes in RA. METHODS:A task force of rheuma...

journal_title：Annals of the rheumatic diseases

authors： Smolen JS,Aletaha D,Bijlsma JW,Breedveld FC,Boumpas D,Burmester G,Combe B,Cutolo M,de Wit M,Dougados M,Emery P,Gibofsky A,Gomez-Reino JJ,Haraoui B,Kalden J,Keystone EC,Kvien TK,McInnes I,Martin-Mola E,Montecucco C,

更新日期：2010-04-01 00:00:00

abstract：OBJECTIVE:To compare responsiveness of the Harris Hip Score with generic measures (that is, the Short Form-36 (SF-36), and a test of walking speed and pain during walking) in patients with osteoarthritis (OA) of the hip. METHOD:The first 75 cases within the population of a randomised clinical trial on manual therapy a...

journal_title：Annals of the rheumatic diseases

authors： Hoeksma HL,Van Den Ende CH,Ronday HK,Heering A,Breedveld FC

更新日期：2003-10-01 00:00:00

abstract：BACKGROUND:Recently, an American College of Rheumatology (ACR)/European League Against Rheumatism (EULAR) collaboration developed new classification criteria for rheumatoid arthritis (RA). OBJECTIVE:To evaluate the diagnostic and discriminative ability of these new criteria compared with the 1987 ACR criteria and the ...

journal_title：Annals of the rheumatic diseases

authors： Britsemmer K,Ursum J,Gerritsen M,van Tuyl LH,van Schaardenburg D

更新日期：2011-08-01 00:00:00

abstract：:Human extensor tendons of the hand were pulled to rupture, and the torn ends, when observed in the scanning electron microscope, appeared to be knotted, possibly owing to the denaturation of the collagen. This confirmed by fluorimetry assays of both the ruptured ends and the middle unbroken sections of the same tendon...

journal_title：Annals of the rheumatic diseases

authors： Minns RJ,Steven FS

更新日期：1980-04-01 00:00:00

abstract：:Four hundred and forty unrelated British Caucasoid patients with rheumatoid arthritis (RA) have been HLA typed for class I and class II antigens. Analyses of HLA antigen associations were performed on the overall group and in patient subsets selected according to particular disease parameters or sex, or both. The resu...

journal_title：Annals of the rheumatic diseases

authors： Jaraquemada D,Ollier W,Awad J,Young A,Silman A,Roitt IM,Corbett M,Hay F,Cosh JA,Maini RN

更新日期：1986-08-01 00:00:00

abstract：OBJECTIVES:Granulocyte colony stimulating factor (GCSF) is important in mobilising neutrophils from the bone marrow but also has a range of proinflammatory effects. We therefore decided to investigate the role of GCSF in antineutrophil cytoplasmic antibody (ANCA) vasculitis. METHODS:We measured GCSF levels in the seru...

journal_title：Annals of the rheumatic diseases

authors： Freeley SJ,Coughlan AM,Popat RJ,Dunn-Walters DK,Robson MG

更新日期：2013-06-01 00:00:00

abstract：OBJECTIVES:A key clinical paradox in osteoarthritis (OA), a prevalent age-related joint disorder characterised by cartilage degeneration and debilitating pain, is that the severity of joint pain does not strictly correlate with radiographic and histological defects in joint tissues. Here, we determined whether protein ...

journal_title：Annals of the rheumatic diseases

authors： Kc R,Li X,Kroin JS,Liu Z,Chen D,Xiao G,Levine B,Li J,Hamilton JL,van Wijnen AJ,Piel M,Shelly DA,Brass D,Kolb E,Im HJ

更新日期：2016-12-01 00:00:00

abstract：:In a comparative study of antinuclear antibodies (ANA) and immune complexes in the serum of 43 patients with systemic sclerosis (SS) ANA were detected by indirect immunofluorescence on Hep 2 cells and/or double immunodiffusion in 90% of patients, while immune complex assays were positive in 32% of patients. The immune...

journal_title：Annals of the rheumatic diseases

authors： French MA,Harrison G,Penning CA,Cunningham J,Hughes P,Rowell NR

更新日期：1985-02-01 00:00:00

abstract：OBJECTIVE:To determine whether the humoral anti-chlamydia antibody response might be related to the ineffective bacterial elimination seen in patients with Chlamydia trachomatis reactive arthritis, particularly in men, who have a higher prevalence of the disease than women. METHODS:The number and specificity of the an...

journal_title：Annals of the rheumatic diseases

authors： Bas S,Scieux C,Vischer TL

更新日期：2001-06-01 00:00:00

abstract：:Previous work has suggested that prior poor reproductive outcome may be a risk factor in rheumatoid arthritis (RA). A case-control study of 195 women with RA and 462 control women from two different sources is presented here. No increase in rates of spontaneous abortion was seen in the women with RA; indeed a protecti...

journal_title：Annals of the rheumatic diseases

authors： Spector TD,Silman AJ

更新日期：1990-01-01 00:00:00