Disease distribution of synovial fluid mast cells and cytophagocytic mononuclear cells in inflammatory arthritis.

abstract：OBJECTIVES:A key clinical paradox in osteoarthritis (OA), a prevalent age-related joint disorder characterised by cartilage degeneration and debilitating pain, is that the severity of joint pain does not strictly correlate with radiographic and histological defects in joint tissues. Here, we determined whether protein ...

journal_title：Annals of the rheumatic diseases

authors： Kc R,Li X,Kroin JS,Liu Z,Chen D,Xiao G,Levine B,Li J,Hamilton JL,van Wijnen AJ,Piel M,Shelly DA,Brass D,Kolb E,Im HJ

更新日期：2016-12-01 00:00:00

abstract：:Fifteen consecutive patients with acute arthritis were studied. Careful culture and microscopy of swabs from mucosal sites were performed to examine the hypothesis that the acute tropical polyarthritis commonly seen in Zimbabwe is due to undiagnosed gonococcal infection. Rheumatic fever and Reiter's disease accounted ...

journal_title：Annals of the rheumatic diseases

authors： Stein CM,Hanly MG

更新日期：1987-12-01 00:00:00

abstract：OBJECTIVES:To further evaluate the role of bacterial antigens in triggering inflammation in the joint in patients with reactive arthritis by studying local antibody synthesis in the joint. METHODS:Yersinia-specific antibodies in paired serum and synovial fluid samples from 29 patients with yersinia triggered reactive ...

journal_title：Annals of the rheumatic diseases

authors： Mäki-Ikola O,Lahesmaa R,Heesemann J,Merilahti-Palo R,Saario R,Toivanen A,Granfors K

更新日期：1994-08-01 00:00:00

abstract：:A 17-year-old female patient with systemic lupus erythematosus (SLE) developed chronic tophaceous gout, chondrocalcinosis and articular capsule calcification in several joints. Analysis of synovial fluid and tophi revealed the coexistence of monosodium urate, calcium pyrophosphate, hydroxyapatite, and cholesterol crys...

journal_title：Annals of the rheumatic diseases

authors： Rodríguez MA,Paul H,Abadí I,Bravo JR,Armas P

更新日期：1984-06-01 00:00:00

abstract：:A 46 year old man presented with a growing mass over his wrist. Erosions of the triquetrum and hamate were present radiographically. Magnetic resonance imaging (MRI) showed a solid mass arising from the extensor carpi ulnaris tendon, which was T(1) hypointense and isointense, T(2) hypointense, and bloomed on gradient ...

journal_title：Annals of the rheumatic diseases

authors： Peh WC,Shek TW,Ip WY

更新日期：2001-06-01 00:00:00

abstract：OBJECTIVES:To elucidate the contribution of HLA-DR-DQ haplotypes and their genotypic combinations to susceptibility to rheumatoid arthritis, and to evaluate the various models for HLA associated risk for the disease in a series of Finnish patients. METHODS:322 Finnish patients with rheumatoid arthritis were typed for ...

journal_title：Annals of the rheumatic diseases

authors： Laivoranta-Nyman S,Möttönen T,Hermann R,Tuokko J,Luukkainen R,Hakala M,Hannonen P,Korpela M,Yli-Kerttula U,Toivanen A,Ilonen J,FIN-RACo Trial Group.

更新日期：2004-11-01 00:00:00

abstract：OBJECTIVES:Annual echocardiography screening is widely used in scleroderma, but the utility of longitudinal assessment is unknown. We evaluated whether change in right ventricular systolic pressure (RVSP) was a risk factor for mortality and development of pulmonary arterial hypertension (PAH) in a cohort of scleroderma...

journal_title：Annals of the rheumatic diseases

authors： Shah AA,Chung SE,Wigley FM,Wise RA,Hummers LK

更新日期：2013-07-01 00:00:00

abstract：OBJECTIVE:To determine whether mild variation in acetabular depth (AD) and shape is a risk factor for osteoarthritis (OA) of the hip. METHODS:The unaffected contralateral hip of patients with unilateral hip OA was compared with hips of asymptomatic controls without hip OA, derived from the Nottingham Genetics Osteoart...

journal_title：Annals of the rheumatic diseases

authors： McWilliams DF,Doherty SA,Jenkins WD,Maciewicz RA,Muir KR,Zhang W,Doherty M

更新日期：2010-10-01 00:00:00

abstract：:Adult human articular cartilage has been maintained in organ culture for 8 days, and the culture medium, which was changed on alternate days, was pooled. Normal and rheumatoid cartilage was obtained from patients and 4 types of culture were prepared: (1) cartilage alone; (2) cartilage + D-penicillamine; (3) cartilage ...

journal_title：Annals of the rheumatic diseases

authors： Jacoby RK

更新日期：1980-02-01 00:00:00

abstract：OBJECTIVES:A prospective randomised trial to compare two different durations of maintenance immunosuppressive therapy for the prevention of relapse in anti-neutrophil cytoplasmic antibodies (ANCA)-associated vasculitis (AAV). METHODS:Patients with AAV were recruited 18-24 months after diagnosis if they were in stable ...

journal_title：Annals of the rheumatic diseases

authors： Karras A,Pagnoux C,Haubitz M,Groot K,Puechal X,Tervaert JWC,Segelmark M,Guillevin L,Jayne D,European Vasculitis Society.

更新日期：2017-10-01 00:00:00

abstract：OBJECTIVES:To develop and validate candidate sets of joints and tendons for assessment of ultrasound (US) joint inflammation in rheumatoid arthritis (RA). METHODS:Patients were included in one of two cohorts from 2010 to June 2013: disease-modifying antirheumatic drug naïve early RA or established RA starting/switchin...

journal_title：Annals of the rheumatic diseases

authors： Aga AB,Hammer HB,Olsen IC,Uhlig T,Kvien TK,van der Heijde D,Fremstad H,Madland TM,Lexberg ÅS,Haukeland H,Rødevand E,Høili C,Stray H,Bendvold AN,Soldal DM,Bakland G,Lie E,Haavardsholm EA

更新日期：2016-08-01 00:00:00

abstract：BACKGROUND:Whether preradiographic lesions in knees at risk for osteoarthritis are incidental versus disease is unclear. We hypothesised, in persons without but at higher risk for knee osteoarthritis, that: 12-48 month MRI lesion status worsening is associated with 12-48 month incident radiographic osteoarthritis (obje...

journal_title：Annals of the rheumatic diseases

authors： Sharma L,Nevitt M,Hochberg M,Guermazi A,Roemer FW,Crema M,Eaton C,Jackson R,Kwoh K,Cauley J,Almagor O,Chmiel JS

更新日期：2016-09-01 00:00:00

abstract：OBJECTIVE:To assess the value of advanced imaging techniques in the detection of hand osteoarthritis (OA) and hand OA progression. METHODS:PubMed/Medline and Embase were searched until April 2012 for studies on imaging of hand OA that presented quantitative data on validity, reliability or responsiveness. Articles pre...

journal_title：Annals of the rheumatic diseases

authors： Saltzherr MS,Selles RW,Bierma-Zeinstra SM,Muradin GS,Coert JH,van Neck JW,Luime JJ

更新日期：2014-02-01 00:00:00

abstract：OBJECTIVE:To compare arterial haemodynamics in adults with long-term juvenile idiopathic arthritis (JIA) to that of healthy controls, and explore the influence of traditional cardiovascular risk factors and disease characteristics on arterial haemodynamics plus coronary artery calcification. METHODS:87 JIA patients (m...

journal_title：Annals of the rheumatic diseases

authors： Aulie HA,Selvaag AM,Günther A,Lilleby V,Molberg Ø,Hartmann A,Holdaas H,Flatø B

更新日期：2015-08-01 00:00:00

abstract：:The effect of transforming growth factor beta (TGF beta) on proteoglycan synthesis and degradation in anatomically intact articular cartilage of murine patellae was studied. Exogenously added TGF beta up to a concentration of 200 pmol/l had no effect on proteoglycan synthesis in intact articular cartilage. Neutralisat...

journal_title：Annals of the rheumatic diseases

authors： van der Kraan PM,Vitters EL,van den Berg WB

更新日期：1992-05-01 00:00:00

abstract：:Thirty two patients with ankylosing spondylitis were investigated with a set of pulmonary function tests and the results compared with those for a control population. The patients had no complaints about lung symptoms and their chest radiographs were normal. The main pathological findings were reduced lung volumes, a ...

journal_title：Annals of the rheumatic diseases

authors： Feltelius N,Hedenström H,Hillerdal G,Hällgren R

更新日期：1986-09-01 00:00:00

abstract：OBJECTIVES:The aim of this study was to determine if neutrophils isolated from the blood and synovial fluid of patients with rheumatoid arthritis had patterns of receptor expression resembling those of blood neutrophils from controls which had been activated and primed in vitro. METHODS:Fluorescence activated cell sor...

journal_title：Annals of the rheumatic diseases

authors： Watson F,Robinson JJ,Phelan M,Bucknall RC,Edwards SW

更新日期：1993-05-01 00:00:00

abstract：:Evidence is presented that a single injection of bacterial antigen in oil into a footpad of rats of 5 strains induced different clinical forms of adjuvant disease in the individual rat strains. Rats were injected with 300 micrograms heat-killed Mycobacterium tuberculosis in 50 microliters paraffin. Inflammatory lesion...

journal_title：Annals of the rheumatic diseases

authors： Muir VY,Dumonde DC

更新日期：1982-10-01 00:00:00

abstract：:This paper presents the second update of the Assessment in SpondyloArthritis international Society (ASAS) consensus statement on the use of anti-tumour necrosis factor (anti-TNF) agents in patients with axial spondyloarthritis (SpA). A major change from the previous recommendations is that patients fulfilling the ASAS...

journal_title：Annals of the rheumatic diseases

authors： van der Heijde D,Sieper J,Maksymowych WP,Dougados M,Burgos-Vargas R,Landewé R,Rudwaleit M,Braun J,Assessment of SpondyloArthritis international Society.

更新日期：2011-06-01 00:00:00

abstract：:Juvenile idiopathic arthritis (JIA) is not a disease, but an exclusion diagnosis that encompasses all forms of arthritis that begin before the age of 16 years, persist for more than 6 weeks, and are of unknown origin. This heterogeneous group of chronic arthritides has been classified on clinical and laboratory ground...

journal_title：Annals of the rheumatic diseases

authors： Martini A

更新日期：2012-09-01 00:00:00

abstract：OBJECTIVES:Development of non-Hodgkin's lymphoma (NHL) is the major adverse outcome of Sjögren's syndrome (SS) affecting both morbidity and mortality. Preliminary evidence suggested that, although not deregulated compared with sicca controls, miR200b-5p levels are decreased in the minor salivary glands (MSGs) of SS pat...

journal_title：Annals of the rheumatic diseases

authors： Kapsogeorgou EK,Papageorgiou A,Protogerou AD,Voulgarelis M,Tzioufas AG

更新日期：2018-08-01 00:00:00

abstract：OBJECTIVES:Antiphospholipid antibodies (aPLA) have been shown to enhance thrombus formation by increasing the expression of adhesive receptors such as P-selectin on endothelial cells. The P-selectin counter-receptor on leucocytes is P-selectin glycoprotein ligand-1 (PSGL-1). We have previously described a variable numb...

journal_title：Annals of the rheumatic diseases

authors： Diz-Kucukkaya R,Inanc M,Afshar-Kharghan V,Zhang QE,López JA,Pekcelen Y

更新日期：2007-10-01 00:00:00

abstract：OBJECTIVE:Calprotectin is a major leucocyte protein, shown to correlate well with laboratory and clinical assessments in several inflammatory rheumatic diseases, and large concentrations of calprotectin have been found in synovial fluid from patients with rheumatoid arthritis (RA). The objective of the present study wa...

journal_title：Annals of the rheumatic diseases

authors： Hammer HB,Odegard S,Fagerhol MK,Landewé R,van der Heijde D,Uhlig T,Mowinckel P,Kvien TK

更新日期：2007-08-01 00:00:00

abstract：:Chondromalacia patellae is difficult to diagnosis clinically with accuracy. In order to clarify the relevant symptoms and signs, 78 patients presenting with a clinical diagnosis of chondromalacia were examined by arthroscopy. In 49% of the knees no abnormalities were found. Presenting symptoms were similar in the norm...

journal_title：Annals of the rheumatic diseases

authors： Leslie IJ,Bentley G

更新日期：1978-12-01 00:00:00

abstract：:Results are reported from the first prospective study of gout in New Zealand Maoris based on a sample of 388 males and 378 females. At baseline, high mean levels of serum uric acid (SUA) were found, 0.422 +/- 0.092 mmol/1 (7.05 +/- 1.54 mg/100 ml) in males and 0.350 +/- 0.091 mmol/1 (5.85 +/- 1.52 mg/100 ml) in female...

journal_title：Annals of the rheumatic diseases

authors： Brauer GW,Prior IA

更新日期：1978-10-01 00:00:00

abstract：:Changes in cellular infiltrate and expression of cytokines, chemokines, and cell adhesion molecules as a result of therapeutic interventions in rheumatoid arthritis can be demonstrated in the synovial membrane. However, before synovial tissue analysis can be used as an outcome measure in such studies, standardisation ...

journal_title：Annals of the rheumatic diseases

authors： Smith MD,Baeten D,Ulfgren AK,McInnes IB,Fitzgerald O,Bresnihan B,Tak PP,Veale D,OMERACT synovial special interests group.

更新日期：2006-01-01 00:00:00

abstract：OBJECTIVE:Domains identified as a result of qualitative research and Delphi exercises to assess rheumatoid arthritis (RA) flare include pain, function, swollen and tender joints, patient and physician global, laboratory measures, participation, stiffness, self-management and fatigue. Here we examine aspects of construc...

journal_title：Annals of the rheumatic diseases

authors： Lie E,Woodworth TG,Christensen R,Kvien TK,Bykerk V,Furst DE,Bingham CO 3rd,Choy EH,OMERACT RA Flare Working Group.

更新日期：2014-10-01 00:00:00

abstract：OBJECTIVES:The impact of immunosuppression on postoperative outcomes has primarily been studied in patients undergoing joint replacement surgery. We aimed to evaluate the impact of biologics and glucocorticoids on outcomes after other major surgeries. METHODS:This retrospective cohort study used Medicare data 2006-201...

journal_title：Annals of the rheumatic diseases

authors： George MD,Baker JF,Winthrop KL,Goldstein SD,Alemao E,Chen L,Wu Q,Xie F,Curtis JR

更新日期：2020-05-01 00:00:00

abstract：OBJECTIVES:Increased numbers of neutrophils expressing proteinase 3 on their membrane (mPR3) have been reported in anti-neutrophil cytoplasm antibody (ANCA)-associated vasculitis (AAV) and are suggested to be involved in AAV immunopathogenesis. In most studies, neutrophils were analysed for mPR3 expression without prim...

journal_title：Annals of the rheumatic diseases

authors： van Rossum AP,Huitema MG,Stegeman CA,Bijl M,de Leeuw K,Van Leeuwen MA,Limburg PC,Kallenberg CG

更新日期：2007-10-01 00:00:00

abstract：OBJECTIVE:To assess the effects of acute stress on inflammatory, haemostatic, rheological, and haemodynamic activity in patients with rheumatoid arthritis (RA) in comparison with patients with osteoarthritis (OA). METHODS:21 patients with RA and 10 with OA underwent a brief mental stress task while standing. Inflammat...

journal_title：Annals of the rheumatic diseases

authors： Veldhuijzen van Zanten JJ,Ring C,Carroll D,Kitas GD

更新日期：2005-09-01 00:00:00