Mild acetabular dysplasia and risk of osteoarthritis of the hip: a case-control study.

abstract：OBJECTIVES:Examine whether osteoarthritis (OA) progression can be delayed by halofuginone in anterior cruciate ligament transection (ACLT) rodent models. METHODS:3-month-old male C57BL/6J (wild type; WT) mice and Lewis rats were randomised to sham-operated, ACLT-operated, treated with vehicle, or ACLT-operated, treate...

journal_title：Annals of the rheumatic diseases

authors： Cui Z,Crane J,Xie H,Jin X,Zhen G,Li C,Xie L,Wang L,Bian Q,Qiu T,Wan M,Xie M,Ding S,Yu B,Cao X

更新日期：2016-09-01 00:00:00

abstract：:In a double blind, single observer, 48 week study the effects of sulphasalazine (2 g daily) and hydroxychloroquine (400 mg daily months 0-6, thereafter 200 mg daily) were compared in 60 patients with definite or classical rheumatoid arthritis. They had not been treated previously with second line drugs. The onset of r...

journal_title：Annals of the rheumatic diseases

authors： Nuver-Zwart IH,van Riel PL,van de Putte LB,Gribnau FW

更新日期：1989-05-01 00:00:00

abstract：:Two patients with sickle cell disease presented with joint pain and early x-ray evidence of articular cartilage loss. Both later developed increasingly destructive arthritis with chronic synovitis identified in synovial biopsies. One patient developed demonstrable aseptic necrosis. Destructive arthropathy is much less...

journal_title：Annals of the rheumatic diseases

authors： Schumacher HR,Dorwart BB,Bond J,Alavi A,Miller W

更新日期：1977-10-01 00:00:00

abstract：:Serum immunoglobulins were measured in 122 patients with ankylosing spondylitis (AS) during various phases of disease activity and compared to those in 58 healthy subjects. The mean serum IgA was 38% higher in patients (306.9 mg/dl) than in controls (222.7 mg/dl) (P < 0.005), but there was no significant difference in...

journal_title：Annals of the rheumatic diseases

authors： Cowling P,Ebringer R,Ebringer A

更新日期：1980-12-01 00:00:00

abstract：OBJECTIVE:To evaluate the presence of anti-PDGFR-alpha antibodies by immunological methods in patients with systemic sclerosis (SSc). METHODS:Fifty-eight women diagnosed with SSc and 36 healthy women controls were included. IgG anti-PDGFR-alpha were measured by ELISA and immunoblot. Associations with clinical and immu...

journal_title：Annals of the rheumatic diseases

authors： Balada E,Simeón-Aznar CP,Ordi-Ros J,Rosa-Leyva M,Selva-O'Callaghan A,Pardos-Gea J,Fonollosa-Pla V,Vilardell-Tarrés M

更新日期：2008-07-01 00:00:00

abstract：OBJECTIVE:To examine the hypothesis that aggrecan, cartilage oligomeric matrix protein (COMP), and bone sialoprotein (BSP) concentrations in synovial fluid could provide information on variations of progression of joint destruction in rheumatoid arthritis. METHODS:Aggrecan, COMP, and BSP were quantified by enzyme link...

journal_title：Annals of the rheumatic diseases

authors： Månsson B,Geborek P,Saxne T

更新日期：1997-02-01 00:00:00

abstract：BACKGROUND:In a prospective observational study, we investigated whether patients with active systemic lupus erythematosus (SLE) had higher indices of endothelial damage and dysfunction than healthy controls and whether improved disease control was associated with improvement in these indices. METHODS:Twenty-seven pat...

journal_title：Annals of the rheumatic diseases

authors： Parker B,Al-Husain A,Pemberton P,Yates AP,Ho P,Gorodkin R,Teh LS,Alexander MY,Bruce IN

更新日期：2014-06-01 00:00:00

abstract：OBJECTIVES:Symptomatic knee osteoarthritis (OA) is a common disabling condition. Attention has tended to focus on the tibiofemoral joint (TFJ). However, there is evidence that the patellofemoral joint (PFJ) is involved in many cases, but its place in the sequence of development and progression of knee OA is unclear. Th...

journal_title：Annals of the rheumatic diseases

authors： Duncan R,Peat G,Thomas E,Hay EM,Croft P

更新日期：2011-11-01 00:00:00

abstract：OBJECTIVES:The aim of this report is to demonstrate pharmacokinetic (PK) and pharmacodynamic (PD) equivalence as well as similar efficacy, safety and immunogenicity between GP2013, a biosimilar rituximab, and innovator rituximab (RTX) in patients with rheumatoid arthritis (RA) with inadequate response or intolerance to...

journal_title：Annals of the rheumatic diseases

authors： Smolen JS,Cohen SB,Tony HP,Scheinberg M,Kivitz A,Balanescu A,Gomez-Reino J,Cen L,Zhu P,Shisha T

更新日期：2017-09-01 00:00:00

abstract：OBJECTIVE:To determine discrepancies in patients' current use and expected future use of the internet for different functions. METHOD:A short questionnaire was developed to assess patients' current use of the internet for three functions: "seeking information", "mutual support", and "care provider contact". This quest...

journal_title：Annals of the rheumatic diseases

authors： van Lankveld WG,Derks AM,van den Hoogen FH

更新日期：2006-01-01 00:00:00

abstract：BACKGROUND/OBJECTIVES:To maintain and optimise the quality of care provided by health professionals in rheumatology (HPRs), adequate educational offerings are needed. This task force (TF) aimed to develop evidence-based recommendations for the generic core competences of HPRs, with specific reference to nurses, physica...

journal_title：Annals of the rheumatic diseases

authors： Edelaar L,Nikiphorou E,Fragoulis GE,Iagnocco A,Haines C,Bakkers M,Barbosa L,Cikes N,Ndosi M,Primdahl J,Prior Y,Pchelnikova P,Ritschl V,Schäfer VS,Smucrova H,Storrønning I,Testa M,Wiek D,Vliet Vlieland TPM

更新日期：2020-01-01 00:00:00

abstract：OBJECTIVE:To define the relationship between autoantigen citrullination and different peptidylarginine deiminase (PAD) enzymes in rheumatoid arthritis (RA). METHODS:Citrullinated autoantigens were identified by immunoblotting control and ionomycin-activated human primary neutrophil lysate with RA sera. Autoantigen ide...

journal_title：Annals of the rheumatic diseases

authors： Darrah E,Rosen A,Giles JT,Andrade F

更新日期：2012-01-01 00:00:00

abstract：:Rheumatoid arthritis (RA) is diagnosed based on phenotypic characteristics. The 2010 ACR/EULAR criteria were derived with the aim of classifying RA earlier in the disease course than the 1987 ACR criteria. When reviewing thus far published validation studies, it is clear that the 2010 criteria can be fulfilled earlier...

journal_title：Annals of the rheumatic diseases

authors： van der Helm-van Mil AH,Huizinga TW

更新日期：2012-10-01 00:00:00

abstract：BACKGROUND:Systemic sclerosis (SSc) is an autoimmune disease characterised by fibrosis of the skin and the internal organs. Except for anticentromere, antitopoisomerase I and antipolymerase III antibodies, there are no reliable circulating markers predicting susceptibility and internal organ complications. This study h...

journal_title：Annals of the rheumatic diseases

authors： van Bon L,Cossu M,Loof A,Gohar F,Wittkowski H,Vonk M,Roth J,van den Berg W,van Heerde W,Broen JC,Radstake TR

更新日期：2014-08-01 00:00:00

abstract：OBJECTIVE:To investigate the relationship between body mass index (BMI) and the incidence and progression of radiological knee as well as of radiological hip osteoarthritis. DESIGN:Cohort study. SETTING:Population based. PARTICIPANTS:3585 people aged > or =55 years were selected from the Rotterdam Study, on the basi...

journal_title：Annals of the rheumatic diseases

authors： Reijman M,Pols HA,Bergink AP,Hazes JM,Belo JN,Lievense AM,Bierma-Zeinstra SM

更新日期：2007-02-01 00:00:00

abstract：OBJECTIVE:To study the associations between structural abnormalities on ultrasound (US) or conventional x-rays (CR) and pain in hand osteoarthritis (HOA). METHODS:In 55 consecutive patients with HOA (mean age 61 years, 86% women) fulfilling the American College of Rheumatology criteria, pain in 30 separate hand joints...

journal_title：Annals of the rheumatic diseases

authors： Kortekaas MC,Kwok WY,Reijnierse M,Huizinga TW,Kloppenburg M

更新日期：2011-10-01 00:00:00

abstract：BACKGROUND AND OBJECTIVE:Serum leptin measures are associated with radiographic knee osteoarthritis, but no studies have examined leptin levels with respect to different measures of knee joint damage from MRI. METHODS:Participants in the Michigan Study of Women's Health Across the Nation underwent bilateral knee MRIs ...

journal_title：Annals of the rheumatic diseases

authors： Karvonen-Gutierrez CA,Harlow SD,Jacobson J,Mancuso P,Jiang Y

更新日期：2014-05-01 00:00:00

abstract：BACKGROUND:Analysis of salivary variables has frequently been proposed as a diagnostic tool for Sjögren's syndrome (SS). Because univocal salivary reference values are lacking, it is currently rather difficult to use sialometry and sialochemistry for diagnosing SS unless major changes have occurred in salivary secretio...

journal_title：Annals of the rheumatic diseases

authors： Kalk WW,Vissink A,Stegenga B,Bootsma H,Nieuw Amerongen AV,Kallenberg CG

更新日期：2002-02-01 00:00:00

abstract：OBJECTIVE:To describe granuloma annulare (GA) skin lesion development in patients during anti-tumour necrosis factor (TNF) therapy. METHODS:199 patients with rheumatoid arthritis and 127 suffering from spondyloarthropathies treated with anti-TNF antagonists were analysed to identify skin lesions suggesting GA. RESULT...

journal_title：Annals of the rheumatic diseases

authors： Voulgari PV,Markatseli TE,Exarchou SA,Zioga A,Drosos AA

更新日期：2008-04-01 00:00:00

abstract：:The relation between common rheumatic diseases such as osteoarthrosis, arthralgia without definite signs of osteoarthrosis, subacromial shoulder pain, different forms of tendinitis, low back pain and neck pain, and the level of formal education, occupational workload and some lifestyle factors were examined in 502 of ...

journal_title：Annals of the rheumatic diseases

authors： Jacobsson L,Lindgärde F,Manthorpe R,Ohlsson K

更新日期：1992-07-01 00:00:00

abstract：OBJECTIVES:Target trial emulation is an intuitive design framework that encourages investigators to formulate their comparative effectiveness research (CER) question as a hypothetical randomised controlled trial (RCT). Our aim was to systematically review CER studies in rheumatoid arthritis (RA) to provide examples of ...

journal_title：Annals of the rheumatic diseases

authors： Zhao SS,Lyu H,Solomon DH,Yoshida K

更新日期：2020-07-01 00:00:00

abstract：OBJECTIVES:To examine whether MRI assessed inflammation and damage in the wrist of patients with early rheumatoid arthritis (RA) are associated with patient-reported outcomes (PROs). METHODS:Wrist and hand MRIs of 210 patients with early RA from two investigator-initiated, randomised controlled studies (CIMESTRA/OPERA...

journal_title：Annals of the rheumatic diseases

authors： Glinatsi D,Baker JF,Hetland ML,Hørslev-Petersen K,Ejbjerg BJ,Stengaard-Pedersen K,Junker P,Ellingsen T,Lindegaard HM,Hansen I,Lottenburger T,Møller JM,Ørnbjerg L,Vestergaard A,Jurik AG,Thomsen HS,Torfing T,Møller-Bisgaa

更新日期：2017-10-01 00:00:00

abstract：OBJECTIVES:To identify new susceptibility loci for Behçet's disease (BD), we performed a genome-wide association study (GWAS) using DNA pooling. METHODS:Two replicate pools of 292 Iranian BD cases and of 294 age- and sex-matched controls were allelotyped in quadruplicate on the Affymetrix Genome-Wide Human SNP Array 6...

journal_title：Annals of the rheumatic diseases

authors： Xavier JM,Shahram F,Sousa I,Davatchi F,Matos M,Abdollahi BS,Sobral J,Nadji A,Oliveira M,Ghaderibarim F,Shafiee NM,Oliveira SA

更新日期：2015-03-01 00:00:00

abstract：OBJECTIVE:To study the association between silica exposure, separately as well as combined with smoking, and the risk of developing rheumatoid arthritis (RA) with or without the presence of antibodies against citrullinated peptide antigens (ACPA). METHODS:This Swedish population based case-control study analysed 577 i...

journal_title：Annals of the rheumatic diseases

authors： Stolt P,Yahya A,Bengtsson C,Källberg H,Rönnelid J,Lundberg I,Klareskog L,Alfredsson L,EIRA Study Group.

更新日期：2010-06-01 00:00:00

abstract：OBJECTIVES:Hyperplasia of synovial fibroblasts, infiltration with lymphocytes and tissue hypoxia are major characteristics of rheumatoid arthritis (RA). Extensive data support a key role for toll-like receptors (TLRs) in RA. Little is known regarding the impact of hypoxia on TLR-induced inflammation in RA. The aim of t...

journal_title：Annals of the rheumatic diseases

authors： Hu F,Mu R,Zhu J,Shi L,Li Y,Liu X,Shao W,Li G,Li M,Su Y,Cohen PL,Qiu X,Li Z

更新日期：2014-05-01 00:00:00

abstract：:A careful selection of 19 patients fitting the classical description of polymyalgia rheumatica have been examined by arthroscopy and thoroughly screened and followed up to exclude rheumatoid arthritis and other disease processes. Synovitis of the shoulder joint has been observed through the arthroscope in 17 and synov...

journal_title：Annals of the rheumatic diseases

authors： Douglas WA,Martin BA,Morris JH

更新日期：1983-06-01 00:00:00

abstract：OBJECTIVES:To compare the effect of a single infusion of zoledronic acid (ZA) with placebo on knee pain and bone marrow lesions (BMLs). METHODS:Adults aged 50-80 years (n=59) with clinical knee osteoarthritis and knee BMLs were randomised to receive either ZA (5 mg/100 ml) or placebo. BMLs were determined using proton...

journal_title：Annals of the rheumatic diseases

authors： Laslett LL,Doré DA,Quinn SJ,Boon P,Ryan E,Winzenberg TM,Jones G

更新日期：2012-08-01 00:00:00

abstract：OBJECTIVES:To analyse the similarities and discrepancies between the official rheumatology specialty training programmes across Europe. METHODS:A steering committee defined the main aspects of training to be assessed. In 2013, the rheumatology official training programmes were reviewed for each of the European League ...

journal_title：Annals of the rheumatic diseases

authors： Sivera F,Ramiro S,Cikes N,Dougados M,Gossec L,Kvien TK,Lundberg IE,Mandl P,Moorthy A,Panchal S,da Silva JA,Bijlsma JW,Working Group on Training in Rheumatology across Europe.

更新日期：2015-06-01 00:00:00

abstract：OBJECTIVE:The RCA alpha block (Regulators of Complement Activation, 1q32) contains critical complement regulatory genes such as CR1 and MCP. This study examined RCA alpha block haplotype associations with both disease susceptibility and diversification of the anti-Ro/La autoantibody response in primary Sjögren syndrome...

journal_title：Annals of the rheumatic diseases

authors： Lester S,McLure C,Williamson J,Bardy P,Rischmueller M,Dawkins RL

更新日期：2008-06-01 00:00:00

abstract：:The possible contribution of immunological mechanisms in the development of Libman-Sacks endocarditis was studied in 2 patients with systemic lupus erythematosus who underwent aortic valve replacement. Sections of verrucous lesions, stained with haematoxylin and eosin, showed three apparently distinct zones: an outer ...

journal_title：Annals of the rheumatic diseases

authors： Shapiro RF,Gamble CN,Wiesner KB,Castles JJ,Wolf AW,Hurley EJ,Salel AF

更新日期：1977-12-01 00:00:00