Arthritis associated with hidradenitis suppurativa.

abstract：:On exposure to sucrose or neutral polysaccharides, cell cultures from human synovium showed cytoplasmic vacuolation, increased numbers of lysosomes, and ultrastructural changes simulating those described in rheumatoid synovial intima and similarly treated embryonic caritlage and bone. These changes were accompanied by...

journal_title：Annals of the rheumatic diseases

authors： Marshall JL,Fraser JR,Muirden KD

更新日期：1977-04-01 00:00:00

abstract：:Thermography before and after joint irrigation at arthroscopy showed no significant improvement of inflammation in 14 patients. Subjectively, those with chondrocalcinosis did best. ...

journal_title：Annals of the rheumatic diseases

authors： Bird HA,Ring EF

更新日期：1978-02-01 00:00:00

abstract：:Two animal models were used to investigate the mode of action of levamisole and thymopoietin. Neither compound influenced the subcutaneous carrageenan air pouch. While thymopoietin inhibited the formation of cotton pellet granulomas, levamisole enhanced it. This supports the conclusions of clinical studies reported el...

journal_title：Annals of the rheumatic diseases

authors： Thrower PA,Sedgwick AD,Smith ER,Willoughby DA,Huskisson EC

更新日期：1983-02-01 00:00:00

abstract：BACKGROUND:Previous data have shown that etanercept levels are associated with clinical response in rheumatoid arthritis. However, for ankylosing spondylitis (AS), data regarding this topic are inconclusive. OBJECTIVES:To investigate the relationship between etanercept levels and clinical response in patients with AS....

journal_title：Annals of the rheumatic diseases

authors： Kneepkens EL,Krieckaert CL,van der Kleij D,Nurmohamed MT,van der Horst-Bruinsma IE,Rispens T,Wolbink GJ

更新日期：2015-10-01 00:00:00

abstract：OBJECTIVE:The zinc-ZIP8-MTF1 axis induces metallothionein (MT) expression and is a catabolic regulator of experimental osteoarthritis (OA) in mice. The main aim of the current study was to explore the roles and underlying molecular mechanisms of MTs in OA pathogenesis. METHODS:Experimental OA in mice was induced by de...

journal_title：Annals of the rheumatic diseases

authors： Won Y,Shin Y,Chun CH,Cho Y,Ha CW,Kim JH,Chun JS

更新日期：2016-11-01 00:00:00

abstract：:Of 29 524 hospitalised medical patients monitored in a drug surveillance programme 1835 (6.2%) received the xanthine oxidase inhibitor allopurinol. After the exclusion of skin reactions adverse effects were attributed to this drug in 33 (1.8%) patients, the most frequent being haematological abnormalities (11 patients...

journal_title：Annals of the rheumatic diseases

authors： McInnes GT,Lawson DH,Jick H

更新日期：1981-06-01 00:00:00

abstract：OBJECTIVES:The aorta inhibits paravertebral ossification in diffuse idiopathic skeletal hyperostosis. We investigated if syndesmophytes in ankylosing spondylitis (AS) occurred less often at the vertebral rim near the aorta. METHODS:We performed thoracolumbar CT scans in 60 subjects in this cross-sectional study. The m...

journal_title：Annals of the rheumatic diseases

authors： Tan S,Dasgupta A,Flynn JA,Ward MM

更新日期：2019-07-01 00:00:00

abstract：BACKGROUND:High rheumatoid arthritis (RA) disease activity during pregnancy is associated with a lower birth weight. Active RA is characterised by high circulating levels of cytokines, which can mediate placental growth and remodelling. OBJECTIVES:To assess the influence of maternal serum cytokine levels on birth weig...

journal_title：Annals of the rheumatic diseases

authors： de Steenwinkel FD,Hokken-Koelega AC,de Man YA,de Rijke YB,de Ridder MA,Hazes JM,Dolhain RJ

更新日期：2013-12-01 00:00:00

abstract：OBJECTIVES:Different prevalences of generalised osteoarthritis (GOA) in patients with knee and hip OA have been reported. The aim of this investigation was to evaluate radiographic and clinical patterns of disease in a hospital based population of patient subgroups with advanced hip and knee OA and to compare the preva...

journal_title：Annals of the rheumatic diseases

authors： Günther KP,Stürmer T,Sauerland S,Zeissig I,Sun Y,Kessler S,Scharf HP,Brenner H,Puhl W

更新日期：1998-12-01 00:00:00

abstract：OBJECTIVES:Systemic immunological processes are profoundly shaped by the micro-environments where antigen recognition occurs. Identifying molecular signatures distinctive of such processes is pivotal to understand pathogenic immune responses and manipulate them for therapeutic purposes. Unfortunately, direct investigat...

journal_title：Annals of the rheumatic diseases

authors： Spreafico R,Rossetti M,van Loosdregt J,Wallace CA,Massa M,Magni-Manzoni S,Gattorno M,Martini A,Lovell DJ,Albani S

更新日期：2016-02-01 00:00:00

abstract：:A method is described for evaluating the progress of patients with back pain. Various symptoms were scored on analogue scales and spinal motion was measured by various techniques. These data were integrated to make subjective and objective indices respectively. Reasonable reproducibility of the measurements was obtain...

journal_title：Annals of the rheumatic diseases

authors： Million R,Nilsen KH,Jayson MI,Baker RD

更新日期：1981-10-01 00:00:00

abstract：OBJECTIVES:The differential diagnosis of seronegative rheumatoid arthritis (negRA) and psoriasis arthritis (PsA) is often difficult due to the similarity of symptoms and the unavailability of reliable clinical markers. Since chronic inflammation induces major changes in the serum metabolome and lipidome, we tested whet...

journal_title：Annals of the rheumatic diseases

authors： Souto-Carneiro M,Tóth L,Behnisch R,Urbach K,Klika KD,Carvalho RA,Lorenz HM

更新日期：2020-04-01 00:00:00

abstract：:This paper presents the second update of the Assessment in SpondyloArthritis international Society (ASAS) consensus statement on the use of anti-tumour necrosis factor (anti-TNF) agents in patients with axial spondyloarthritis (SpA). A major change from the previous recommendations is that patients fulfilling the ASAS...

journal_title：Annals of the rheumatic diseases

authors： van der Heijde D,Sieper J,Maksymowych WP,Dougados M,Burgos-Vargas R,Landewé R,Rudwaleit M,Braun J,Assessment of SpondyloArthritis international Society.

更新日期：2011-06-01 00:00:00

abstract：OBJECTIVE:To determine the significance of quantitative levels of antibodies to cyclic citrullinated peptides (anti-CCP) in a population of patients with rheumatoid arthritis (RA). METHODS:A total of 241 consecutive sera from patients with RA sent from a large rheumatology clinic for laboratory testing were selected f...

journal_title：Annals of the rheumatic diseases

authors： Lee DM,Phillips R,Hagan EM,Chibnik LB,Costenbader KH,Schur PH

更新日期：2009-02-01 00:00:00

abstract：BACKGROUND:Medical management of adults with osteoarthritis (OA) who require non-steroidal anti-inflammatory drugs (NSAIDs) must be decided after assessing prevalent gastrointestinal (GI) and cardiovascular (CV) risks in the individual patient. OBJECTIVE:To evaluate the GI and CV risk profile of patients with OA who r...

journal_title：Annals of the rheumatic diseases

authors： Lanas A,Tornero J,Zamorano JL

更新日期：2010-08-01 00:00:00

abstract：OBJECTIVE:Systemic lupus erythematosus (SLE) is a systemic autoimmune disease with unknown aetiology. Epstein-Barr virus (EBV) is an environmental factor associated with SLE. EBV maintains latency in B cells with frequent reactivation measured by antibodies against viral capsid antigen (VCA) and early antigen (EA). In ...

journal_title：Annals of the rheumatic diseases

authors： Jog NR,Young KA,Munroe ME,Harmon MT,Guthridge JM,Kelly JA,Kamen DL,Gilkeson GS,Weisman MH,Karp DR,Gaffney PM,Harley JB,Wallace DJ,Norris JM,James JA

更新日期：2019-09-01 00:00:00

abstract：:It is postulated that the mobile inflamed joint may be subject to cyclical ischaemic reperfusion injury. Xanthine oxidoreductase is an enzyme thought to contribute to oxidative reperfusion injury, and the detection of this activity in human synovium is described. Three normal and five rheumatoid tissues were assayed w...

journal_title：Annals of the rheumatic diseases

authors： Allen RE,Outhwaite JM,Morris CJ,Blake DR

更新日期：1987-11-01 00:00:00

abstract：:Results are reported from the first prospective study of gout in New Zealand Maoris based on a sample of 388 males and 378 females. At baseline, high mean levels of serum uric acid (SUA) were found, 0.422 +/- 0.092 mmol/1 (7.05 +/- 1.54 mg/100 ml) in males and 0.350 +/- 0.091 mmol/1 (5.85 +/- 1.52 mg/100 ml) in female...

journal_title：Annals of the rheumatic diseases

authors： Brauer GW,Prior IA

更新日期：1978-10-01 00:00:00

abstract：OBJECTIVE:To compare the efficacy and safety between tocilizumab added to methotrexate and tocilizumab switched from methotrexate in patients with active rheumatoid arthritis (RA). METHODS:This is a 2-year randomised, controlled study. RA patients with moderate or high disease activity despite methotrexate were random...

journal_title：Annals of the rheumatic diseases

authors： Kaneko Y,Atsumi T,Tanaka Y,Inoo M,Kobayashi-Haraoka H,Amano K,Miyata M,Murakawa Y,Yasuoka H,Hirata S,Nagasawa H,Tanaka E,Miyasaka N,Yamanaka H,Yamamoto K,Takeuchi T

更新日期：2016-11-01 00:00:00

abstract：OBJECTIVE:To determine whether 17beta-oestradiol (E2) modulates interleukin (IL) 1beta-induced proteoglycan degradation in chondrocytes, and to analyse the part played by metalloproteinases (MMPs) in this process. METHODS:Primary cultured rabbit articular chondrocytes were prepared and treated with 10 ng/ml IL1beta co...

journal_title：Annals of the rheumatic diseases

authors： Richette P,Dumontier MF,François M,Tsagris L,Korwin-Zmijowska C,Rannou F,Corvol MT

更新日期：2004-02-01 00:00:00

abstract：OBJECTIVE:To evaluate the nature of positional changes of humeroulnar (HU) and humeroradial (HR) joints in a cohort of 74 patients with seropositive and erosive rheumatoid arthritis (RA) followed up prospectively. METHODS:At the 15 year follow up standard anteroposterior and lateral radiographs of 148 elbow joints wer...

journal_title：Annals of the rheumatic diseases

authors： Lehtinen JT,Kaarela K,Kauppi MJ,Belt EA,Mäenpää H,Kuusela P,Lehto MU

更新日期：2001-08-01 00:00:00

abstract：OBJECTIVES:To study the ability of technetium-99m hexamethyl propylene amineoxime (HMPAO) labelled lymphocyte scintigraphy to quantify synovial inflammation, and to analyse the kinetics of lymphocyte retention in the joints of patients with rheumatoid arthritis (RA). METHODS:After isolation of the lymphocytes, the cel...

journal_title：Annals of the rheumatic diseases

authors： Jorgensen C,Couret I,Bologna C,Rossi M,Sany J

更新日期：1995-01-01 00:00:00

abstract：OBJECTIVE:To define the mechanisms whereby methotrexate (MTX) manifests its effects in patients with rheumatoid arthritis. METHODS:T and B cells from peripheral blood and rheumatoid synovial tissues, synovial adherent cells, and the human fibrosarcoma cell line HT1080 and its mutant (defective in an enzyme in the nucl...

journal_title：Annals of the rheumatic diseases

authors： Nakajima A,Hakoda M,Yamanaka H,Kamatani N,Kashiwazaki S

更新日期：1996-04-01 00:00:00

abstract：:In a comparative study of antinuclear antibodies (ANA) and immune complexes in the serum of 43 patients with systemic sclerosis (SS) ANA were detected by indirect immunofluorescence on Hep 2 cells and/or double immunodiffusion in 90% of patients, while immune complex assays were positive in 32% of patients. The immune...

journal_title：Annals of the rheumatic diseases

authors： French MA,Harrison G,Penning CA,Cunningham J,Hughes P,Rowell NR

更新日期：1985-02-01 00:00:00

abstract：BACKGROUND:The MEFV gene is responsible for familial Mediterranean fever (FMF). Several disease associated mutations have been identified. The range of genetic variation in MEFV in Greek patients has not been determined. OBJECTIVE:To describe a method that facilitates the routine screening of the entire coding sequenc...

journal_title：Annals of the rheumatic diseases

authors： Ritis K,Giaglis S,Spathari N,Micheli A,Zonios D,Tzoanopoulos D,Deltas CC,Rafail S,Mean R,Papadopoulos V,Tzioufas AG,Moutsopoulos HM,Kartalis G

更新日期：2004-04-01 00:00:00

abstract：OBJECTIVE:To determine the serum levels of nucleosome in patients with systemic sclerosis (SSc) and relate the results to the clinical features of SSc. METHODS:Serum nucleosome levels in 91 patients with SSc were examined by ELISA. The expression of Toll-like receptor (TLR) 9 in T and B cells was quantified by flow cy...

journal_title：Annals of the rheumatic diseases

authors： Yoshizaki A,Taniguchi T,Saigusa R,Fukasawa T,Ebata S,Numajiri H,Nakamura K,Yamashita T,Takahashi T,Toyama T,Asano Y,Tedder TF,Sato S

更新日期：2016-10-01 00:00:00

abstract：OBJECTIVE:To evaluate concentrations of the platelet activation markers beta thromboglobulin (BTG) and platelet factor 4 (PF4) in bronchoalveolar lavage fluid (BALF) from patients with systemic sclerosis with and without scleroderma interstitial lung disease (SLD). METHODS:BTG and PF-4 were measured by enzyme immunoas...

journal_title：Annals of the rheumatic diseases

authors： Kowal-Bielecka O,Kowal K,Lewszuk A,Bodzenta-Lukaszyk A,Walecki J,Sierakowski S

更新日期：2005-03-01 00:00:00

abstract：OBJECTIVE:To determine the relationship of disease activity to infections in patients with rheumatoid arthritis (RA). METHODS:From the CORRONA database, the incidence of physician-reported infections in RA patients on stable disease-modifying antirheumatic drug, biological, and corticosteroid therapy for at least 6 mo...

journal_title：Annals of the rheumatic diseases

authors： Au K,Reed G,Curtis JR,Kremer JM,Greenberg JD,Strand V,Furst DE,CORRONA Investigators.

更新日期：2011-05-01 00:00:00

abstract：BACKGROUND:Immunogenicity of aTNFs is one of the mechanisms behind treatment failure. OBJECTIVE:To assess the effect of anti-drug antibodies (ADA) on drug response to infliximab, adalimumab and etanercept, and the effect of immunosuppression on ADA detection, in patients with Rheumatoid Arthritis, Spondyloarthritis, P...

journal_title：Annals of the rheumatic diseases

authors： Garcês S,Demengeot J,Benito-Garcia E

更新日期：2013-12-01 00:00:00

abstract：:Treatment of rheumatoid arthritis (RA) may differ among rheumatologists and currently, clear and consensual international recommendations on RA treatment are not available. In this paper recommendations for the treatment of RA with synthetic and biological disease-modifying antirheumatic drugs (DMARDs) and glucocortic...

journal_title：Annals of the rheumatic diseases

authors： Smolen JS,Landewé R,Breedveld FC,Dougados M,Emery P,Gaujoux-Viala C,Gorter S,Knevel R,Nam J,Schoels M,Aletaha D,Buch M,Gossec L,Huizinga T,Bijlsma JW,Burmester G,Combe B,Cutolo M,Gabay C,Gomez-Reino J,Kouloumas M

更新日期：2010-06-01 00:00:00