Enhanced membrane expression of the 52 kDa Ro(SS-A) and La(SS-B) antigens by human keratinocytes induced by TNF alpha.

abstract：:Three patients presented with septal fasciitis and panniculitis, associated with clinical and laboratory features which precluded straight-forward classification into eosinophilic fasciitis, localised scleroderma, or lupus erythematosus profundus. Treatment with cimetidine caused the remission of cutaneous manifestati...

journal_title：Annals of the rheumatic diseases

authors： Naschitz JE,Yeshurun D,Rosner I,Abrahamson JE,Misselevitch I,Boss JH

更新日期：1990-10-01 00:00:00

abstract：OBJECTIVE:To confirm and extend the immunopathological evidence of effects of infliximab on the synovium in active spondyloarthropathy. METHODS:Synovial biopsies obtained in patients with spondyloarthropathy at baseline and week 12 were stained and scored by two independent observers. Two study populations were evalua...

journal_title：Annals of the rheumatic diseases

authors： Kruithof E,Baeten D,Van den Bosch F,Mielants H,Veys EM,De Keyser F

更新日期：2005-04-01 00:00:00

abstract：:The response of synovial lymphocytes from a 65-year-old lady with persistent polyarthritis, to rubella antigen and a number of other microbial agents was studied over a period of 11 months by [3H]thymidine incorporation. The results were correlated with the ability to isolate rubella virus from both peripheral blood a...

journal_title：Annals of the rheumatic diseases

authors： Chantler JK,da Roza DM,Bonnie ME,Reid GD,Ford DK

更新日期：1985-08-01 00:00:00

abstract：BACKGROUND:Diagnosis of active pulmonary and paranasal involvement in patients with Wegener's granulomatosis (WG) can be difficult. The diagnostic value of gallium-67 scintigraphy in WG is unclear. OBJECTIVE:To evaluate the added diagnostic value of gallium-67 scintigraphy in patients with WG with suspected granulomat...

journal_title：Annals of the rheumatic diseases

authors： Slart RH,Jager PL,Poot L,Piers DA,Tervaert JW,Stegeman CA

更新日期：2003-07-01 00:00:00

abstract：OBJECTIVE:High serum interferon α (IFNα) activity is a heritable risk factor for systemic lupus erythematosus (SLE). Auto-antibodies found in SLE form immune complexes which can stimulate IFNα production by activating endosomal Toll-like receptors and interferon regulatory factors (IRFs), including IRF5. Genetic variat...

journal_title：Annals of the rheumatic diseases

authors： Niewold TB,Kelly JA,Kariuki SN,Franek BS,Kumar AA,Kaufman KM,Thomas K,Walker D,Kamp S,Frost JM,Wong AK,Merrill JT,Alarcón-Riquelme ME,Tikly M,Ramsey-Goldman R,Reveille JD,Petri MA,Edberg JC,Kimberly RP,Alarcón GS,

更新日期：2012-03-01 00:00:00

abstract：:Human extensor tendons of the hand were pulled to rupture, and the torn ends, when observed in the scanning electron microscope, appeared to be knotted, possibly owing to the denaturation of the collagen. This confirmed by fluorimetry assays of both the ruptured ends and the middle unbroken sections of the same tendon...

journal_title：Annals of the rheumatic diseases

authors： Minns RJ,Steven FS

更新日期：1980-04-01 00:00:00

abstract：:A family with features of the mucocutaneous ocular syndrome is described. A 4-generation study reveals that the condition has been inherited as an autosomal dominant trait with variable expressivity. Psychiatric symptoms and myalgia have been prominent features peculiar to our patients. ...

journal_title：Annals of the rheumatic diseases

authors： Berman L,Trappler B,Jenkins T

更新日期：1979-04-01 00:00:00

abstract：OBJECTIVES:The Psoriatic Arthritis Impact of Disease (PsAID) Questionnaire is a recently developed patient-reported outcome measure (PROM) of disease impact in psoriatic arthritis (PsA). We set out to assess the validity in an independent cohort of patients, estimate the minimally important difference for improvement a...

journal_title：Annals of the rheumatic diseases

authors： Holland R,Tillett W,Korendowych E,Cavill C,Waldron N,Brooke M,McHugh NJ

更新日期：2018-03-01 00:00:00

abstract：OBJECTIVE:To compare responsiveness of the Harris Hip Score with generic measures (that is, the Short Form-36 (SF-36), and a test of walking speed and pain during walking) in patients with osteoarthritis (OA) of the hip. METHOD:The first 75 cases within the population of a randomised clinical trial on manual therapy a...

journal_title：Annals of the rheumatic diseases

authors： Hoeksma HL,Van Den Ende CH,Ronday HK,Heering A,Breedveld FC

更新日期：2003-10-01 00:00:00

abstract：OBJECTIVE:To identify predictors of radiographic progression in a 2-year randomised, double-blind, clinical study (CIMESTRA) of patients with early rheumatoid arthritis (RA). METHODS:Patients with early RA (n = 130) were treated with methotrexate, intra-articular betamethasone and ciclosporin/placebo-ciclosporin. Base...

journal_title：Annals of the rheumatic diseases

authors： Hetland ML,Ejbjerg B,Hørslev-Petersen K,Jacobsen S,Vestergaard A,Jurik AG,Stengaard-Pedersen K,Junker P,Lottenburger T,Hansen I,Andersen LS,Tarp U,Skjødt H,Pedersen JK,Majgaard O,Svendsen AJ,Ellingsen T,Lindegaard H,C

更新日期：2009-03-01 00:00:00

abstract：OBJECTIVE:The technique and results of a special oblique radiograph of the hip called the "faux profil" (FP) of the hip are described. The FP was evaluated for the detection of joint space narrowing in incipient osteoarthritis of the hip (OAH) as compared with the anteroposterior (AP) radiograph. METHODS:58 hips with ...

journal_title：Annals of the rheumatic diseases

authors： Lequesne MG,Laredo JD

更新日期：1998-11-01 00:00:00

abstract：OBJECTIVE:To assess the value of advanced imaging techniques in the detection of hand osteoarthritis (OA) and hand OA progression. METHODS:PubMed/Medline and Embase were searched until April 2012 for studies on imaging of hand OA that presented quantitative data on validity, reliability or responsiveness. Articles pre...

journal_title：Annals of the rheumatic diseases

authors： Saltzherr MS,Selles RW,Bierma-Zeinstra SM,Muradin GS,Coert JH,van Neck JW,Luime JJ

更新日期：2014-02-01 00:00:00

abstract：OBJECTIVES:To develop and validate candidate sets of joints and tendons for assessment of ultrasound (US) joint inflammation in rheumatoid arthritis (RA). METHODS:Patients were included in one of two cohorts from 2010 to June 2013: disease-modifying antirheumatic drug naïve early RA or established RA starting/switchin...

journal_title：Annals of the rheumatic diseases

authors： Aga AB,Hammer HB,Olsen IC,Uhlig T,Kvien TK,van der Heijde D,Fremstad H,Madland TM,Lexberg ÅS,Haukeland H,Rødevand E,Høili C,Stray H,Bendvold AN,Soldal DM,Bakland G,Lie E,Haavardsholm EA

更新日期：2016-08-01 00:00:00

abstract：OBJECTIVE:To investigate the incidence of new cancer diagnoses in a community sample of patients with polymyalgia rheumatica (PMR). METHODS:All incident cases of PMR in the UK General Practice Research Database (GPRD) (1987-99), without pre-existing cancer or vascular disease and treated with corticosteroids (n=2877) ...

journal_title：Annals of the rheumatic diseases

authors： Muller S,Hider SL,Belcher J,Helliwell T,Mallen CD

更新日期：2014-10-01 00:00:00

abstract：:The effects of fasting for 7 days were investigated in 13 patients with rheumatoid arthritis (RA) in comparison with a control regimen in a cross-over trial. The effects of fasting on clinical performance and blood neutrophil functions were studied. During fasting, with a mean weight loss of 5.1 kg, clinical inflammat...

journal_title：Annals of the rheumatic diseases

authors： Udén AM,Trang L,Venizelos N,Palmblad J

更新日期：1983-02-01 00:00:00

abstract：OBJECTIVE:To evaluate salivary hyaluronic acid (HA) concentration in patients with primary Sjögren's syndrome (SS). METHODS:Salivary and serum HA concentrations were evaluated using a radiometric assay. Thirty nine patients with SS served as the study group and their results were compared with 19 patients having clini...

journal_title：Annals of the rheumatic diseases

authors： Tishler M,Yaron I,Shirazi I,Yaron M

更新日期：1998-08-01 00:00:00

abstract：BACKGROUND:In the synovial membrane of patients with rheumatoid arthritis (RA), a strong expression of laminins and matrix degrading proteases was reported. AIM:To investigate the regulation of matrix metalloproteinases (MMPs) in synovial fibroblasts (SFs) of patients with osteoarthritis (OA) and RA by attachment to l...

journal_title：Annals of the rheumatic diseases

authors： Hoberg M,Rudert M,Pap T,Klein G,Gay S,Aicher WK

更新日期：2007-04-01 00:00:00

abstract：:Reproducibility along a vertical 10 cm visual analogue scale (VAS) was investigated. Eight normal volunteers attempted to duplicate a set of marked VAS. There was a tendency to estimate too high on the scale, and reproducibility was found to be variable along its length. This indicates that the error involved in the u...

journal_title：Annals of the rheumatic diseases

authors： Dixon JS,Bird HA

更新日期：1981-02-01 00:00:00

abstract：:The complement system plays a major role in the autoimmune disease, systemic lupus erythematosus (SLE). However, the role of complement in SLE is complex since it may both prevent and exacerbate the disease. In this review, we explore the latest findings in complement-focused research in SLE. C1q deficiency is the str...

journal_title：Annals of the rheumatic diseases

authors： Leffler J,Bengtsson AA,Blom AM

更新日期：2014-09-01 00:00:00

abstract：:The radiographic changes of ankylosing spondylitis were studied in 50 females and 82 males. There was a tendency for the males to have more severe arthritic changes in the sacroiliac joints than the females, but the difference did not reach statistical significance. Males significantly more often had radiological invo...

journal_title：Annals of the rheumatic diseases

authors： Gran JT,Husby G,Hordvik M,Størmer J,Romberg-Andersen O

更新日期：1984-08-01 00:00:00

abstract：:Serum C2 activity was measured in 135 individuals drawn from a panel of 418 tissue-typed blood donors. The study group included all donors with HLA antigens A10 and B18. Heterozygote C2 deficiency (C2Dhet) was defined by reference to the range of C2 activity in previously studied obligate heterozygotes. Five donors we...

journal_title：Annals of the rheumatic diseases

authors： Rynes RI,Britten AF,Pickering RJ

更新日期：1982-02-01 00:00:00

abstract：:Purified peripheral blood polymorphonuclear leucocytes (PMNs) from patients with rheumatoid arthritis (RA) have been found to differ from purified PMNs from normal subjects in ways that are consistent with their prior activation. However, it is currently contentious whether activated PMNs really circulate in patients ...

journal_title：Annals of the rheumatic diseases

authors： McCarthy DA,Bernhagen J,Taylor MJ,Hamblin AS,James I,Thompson PW,Perry JD

更新日期：1992-01-01 00:00:00

abstract：OBJECTIVES:Classification criteria are biased towards classifying long-standing disease. We compared the European League Against Rheumatism (EULAR)/American College of Rheumatology (ACR)-2019, Systemic Lupus International Collaborating Clinics (SLICC)-2012 and ACR-1997 criteria in an early (median 48 months) systemic l...

journal_title：Annals of the rheumatic diseases

authors： Adamichou C,Nikolopoulos D,Genitsaridi I,Bortoluzzi A,Fanouriakis A,Papastefanakis E,Kalogiannaki E,Gergianaki I,Sidiropoulos P,Boumpas DT,Bertsias GK

更新日期：2020-02-01 00:00:00

abstract：OBJECTIVES:In salivary glands from patients with Sjögren syndrome, overexpression of laminins 1 and 5 and disorganisation of the acinar basal lamina have been reported. Laminin 5 mediates association of the basal lamina with epithelial cells by forming adhesion complexes upon interaction with alpha6beta4 integrin. In t...

journal_title：Annals of the rheumatic diseases

authors： Velozo J,Aguilera S,Alliende C,Ewert P,Molina C,Pérez P,Leyton L,Quest A,Brito M,González S,Leyton C,Hermoso M,Romo R,González MJ

更新日期：2009-06-01 00:00:00

abstract：:A 46 year old man presented with a growing mass over his wrist. Erosions of the triquetrum and hamate were present radiographically. Magnetic resonance imaging (MRI) showed a solid mass arising from the extensor carpi ulnaris tendon, which was T(1) hypointense and isointense, T(2) hypointense, and bloomed on gradient ...

journal_title：Annals of the rheumatic diseases

authors： Peh WC,Shek TW,Ip WY

更新日期：2001-06-01 00:00:00

abstract：OBJECTIVE:To assess the diagnostic value of ultrasonography (US) in the evaluation of arthritic shoulder joints. METHODS:Twenty shoulders of 20 inpatients with arthritis were evaluated by US one day before the shoulder operation. Changes in the subacromial-subdeltoid bursa, biceps tendon and tendon sheath, rotatof cuf...

journal_title：Annals of the rheumatic diseases

authors： Alasaarela E,Leppilahti J,Hakala M

更新日期：1998-06-01 00:00:00

abstract：:In osteoarthritis (OA), adult articular chondrocytes undergo phenotypic modulation in response to alterations in the environment owing to mechanical injury and inflammation. These processes not only stimulate the production of enzymes that degrade the cartilage matrix but also inhibit repair. With the use of in vitro ...

journal_title：Annals of the rheumatic diseases

authors： Goldring MB,Otero M,Tsuchimochi K,Ijiri K,Li Y

更新日期：2008-12-01 00:00:00

abstract：:Biological therapies directed at proinflammatory cytokines have irrevocably changed the landscape of treatment of rheumatoid arthritis (RA) and other autoimmune diseases. With the advances in our knowledge in cytokine signalling, the question emerges whether targeting intracellular signalling might also be a safe and ...

journal_title：Annals of the rheumatic diseases

authors： O'Shea JJ,Kontzias A,Yamaoka K,Tanaka Y,Laurence A

更新日期：2013-04-01 00:00:00

abstract：OBJECTIVE:To assess and characterise the risk of bladder cancer, and its relation to cyclophosphamide, in patients with Wegener's granulomatosis. METHODS:In the population based, nationwide Swedish Inpatient Register a cohort of 1065 patients with Wegener's granulomatosis, 1969-95, was identified. Through linkage with...

journal_title：Annals of the rheumatic diseases

authors： Knight A,Askling J,Granath F,Sparen P,Ekbom A

更新日期：2004-10-01 00:00:00

abstract：:Antibodies to cytomegalovirus (CMV) and Epstein-Barr virus capsid antigen (EBVCA) were examined in 41 patients with rheumatoid arthritis (RA), 26 patients with primary sicca syndrome, and 26 healthy subjects of similar age and sex. IgG antibody titres to EBVCA and CMV were similar in all three groups, apart from a tri...

journal_title：Annals of the rheumatic diseases

authors： Venables PJ,Ross MG,Charles PJ,Melsom RD,Griffiths PD,Maini RN

更新日期：1985-11-01 00:00:00