Behçet's syndrome: a family study and the elucidation of a genetic role.

Abstract:

:A family with features of the mucocutaneous ocular syndrome is described. A 4-generation study reveals that the condition has been inherited as an autosomal dominant trait with variable expressivity. Psychiatric symptoms and myalgia have been prominent features peculiar to our patients.

journal_name

Ann Rheum Dis

authors

Berman L,Trappler B,Jenkins T

doi

10.1136/ard.38.2.118

subject

Has Abstract

pub_date

1979-04-01 00:00:00

pages

118-21

issue

2

eissn

0003-4967

issn

1468-2060

journal_volume

38

pub_type

杂志文章
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    abstract:OBJECTIVES:To compare the efficacy and safety of lumiracoxib with placebo and celecoxib for osteoarthritis OA in a 13 week, multicentre, randomised, double blind study. METHODS:After a 37 day washout period for nonsteroidal antiinflammatory drugs, 1702 patients with knee OA were randomised to lumiracoxib 200 or 400 mg...

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    doi:10.1136/ard.2003.015974

    authors: Tannenbaum H,Berenbaum F,Reginster JY,Zacher J,Robinson J,Poor G,Bliddal H,Uebelhart D,Adami S,Navarro F,Lee A,Moore A,Gimona A

    更新日期:2004-11-01 00:00:00

  • A new era in the management of pulmonary arterial hypertension related to scleroderma: endothelin receptor antagonism.

    abstract::Evidence suggests that endothelin may have a fundamental role in scleroderma pathogenesis, including pulmonary arterial hypertension (PAH)--a leading cause of death in patients with scleroderma. Development of a new class of drug, endothelin receptor antagonists, heralds an improved outlook for patients with scleroder...

    journal_title:Annals of the rheumatic diseases

    pub_type: 杂志文章,评审

    doi:10.1136/ard.2003.017673

    authors: Hachulla E,Coghlan JG

    更新日期:2004-09-01 00:00:00

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    abstract:OBJECTIVE:To investigate the membrane expression of the 52 kDa Ro(SS-A) and La(SS-B) antigens in human keratinocytes under the influence of an important mediator of inflammation, TNF alpha. METHODS:Keratinocytes, isolated from human skins obtained at circumcision and identified using monoclonal antibodies, were treate...

    journal_title:Annals of the rheumatic diseases

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    doi:10.1136/ard.54.11.904

    authors: Dörner T,Hucko M,Mayet WJ,Trefzer U,Burmester GR,Hiepe F

    更新日期:1995-11-01 00:00:00

  • Bacterial and viral superantigens: roles in autoimmunity?

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    journal_title:Annals of the rheumatic diseases

    pub_type: 杂志文章,评审

    doi:10.1136/ard.52.suppl_1.s6

    authors: Acha-Orbea H

    更新日期:1993-03-01 00:00:00

  • Prospective two year follow up study comparing novel and conventional imaging procedures in patients with arthritic finger joints.

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    journal_title:Annals of the rheumatic diseases

    pub_type: 杂志文章

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    authors: Backhaus M,Burmester GR,Sandrock D,Loreck D,Hess D,Scholz A,Blind S,Hamm B,Bollow M

    更新日期:2002-10-01 00:00:00

  • Type II collagen is a target antigen of clonally expanded T cells in the synovium of patients with rheumatoid arthritis.

    abstract:OBJECTIVE:To investigate whether type II collagen (CII) is recognised by oligoclonally expanded synovial T cells of patients with rheumatoid arthritis (RA). METHODS:Peripheral blood mononuclear cells (PBMC) from 15 RA patients were stimulated with CII in vitro. T cell clones expanded by such stimulation were compared ...

    journal_title:Annals of the rheumatic diseases

    pub_type: 杂志文章

    doi:10.1136/ard.58.7.446

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  • Phenotypic and genotypic analysis of mononuclear cells from patients with Felty's syndrome.

    abstract::Phenotypic and genotypic characteristics of the peripheral blood mononuclear cells in nine patients with Felty's syndrome have been examined. One patient had an increased number and percentage of peripheral blood mononuclear cells with the phenotype CD3+ Leu-7+ CD16+ and showed a clonal rearrangement of the T cell rec...

    journal_title:Annals of the rheumatic diseases

    pub_type: 杂志文章

    doi:10.1136/ard.49.2.103

    authors: Ahern MJ,Roberts-Thomson PJ,Bradley J,Story C,Seshadri P

    更新日期:1990-02-01 00:00:00

  • Mild acetabular dysplasia and risk of osteoarthritis of the hip: a case-control study.

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    journal_title:Annals of the rheumatic diseases

    pub_type: 杂志文章

    doi:10.1136/ard.2009.127076

    authors: McWilliams DF,Doherty SA,Jenkins WD,Maciewicz RA,Muir KR,Zhang W,Doherty M

    更新日期:2010-10-01 00:00:00

  • Circulating maternal cytokines influence fetal growth in pregnant women with rheumatoid arthritis.

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    journal_title:Annals of the rheumatic diseases

    pub_type: 杂志文章,多中心研究

    doi:10.1136/annrheumdis-2012-202539

    authors: de Steenwinkel FD,Hokken-Koelega AC,de Man YA,de Rijke YB,de Ridder MA,Hazes JM,Dolhain RJ

    更新日期:2013-12-01 00:00:00

  • Mutual antagonism of rheumatoid arthritis and hay fever; a role for type 1/type 2 T cell balance.

    abstract:OBJECTIVES:The balance between interferon gamma (IFN gamma) and interleukin 4 (IL4) producing T cells (T1 and T2 cells) seems to be of importance in many (auto)immune disorders. In general, T1 cell activity is important in cellular immunity whereas T2 cell activity plays a part in humoral responses. T1 cell activity pr...

    journal_title:Annals of the rheumatic diseases

    pub_type: 杂志文章

    doi:10.1136/ard.57.5.275

    authors: Verhoef CM,van Roon JA,Vianen ME,Bruijnzeel-Koomen CA,Lafeber FP,Bijlsma JW

    更新日期:1998-05-01 00:00:00

  • The relation between progressive osteoarthritis of the knee and long term progression of osteoarthritis of the hand, hip, and lumbar spine.

    abstract:BACKGROUND:The association between progression of knee osteoarthritis and progression of osteoarthritis at sites distant from the knee is unclear because of a lack of multisite longitudinal progression data. OBJECTIVE:To examine the association between radiological progression of knee osteoarthritis and osteoarthritis...

    journal_title:Annals of the rheumatic diseases

    pub_type: 杂志文章

    doi:10.1136/ard.2005.038414

    authors: Hassett G,Hart DJ,Doyle DV,March L,Spector TD

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  • Blood-based test for diagnosis and functional subtyping of familial Mediterranean fever.

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    pub_type: 杂志文章

    doi:10.1136/annrheumdis-2019-216701

    authors: Van Gorp H,Huang L,Saavedra P,Vuylsteke M,Asaoka T,Prencipe G,Insalaco A,Ogunjimi B,Jeyaratnam J,Cataldo I,Jacques P,Vermaelen K,Dullaers M,Joos R,Sabato V,Stella A,Frenkel J,De Benedetti F,Dehoorne J,Haerynck F,C

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    journal_title:Annals of the rheumatic diseases

    pub_type: 杂志文章

    doi:10.1136/ard.50.12.917

    authors: Merry P,Williams R,Cox N,King JB,Blake DR

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  • Sex differences in the association between body mass index and total hip or knee joint replacement resulting from osteoarthritis.

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    journal_title:Annals of the rheumatic diseases

    pub_type: 杂志文章

    doi:10.1136/ard.2007.086868

    authors: Franklin J,Ingvarsson T,Englund M,Lohmander LS

    更新日期:2009-04-01 00:00:00

  • High level of functional dickkopf-1 predicts protection from syndesmophyte formation in patients with ankylosing spondylitis.

    abstract:INTRODUCTION:The molecular mechanisms of syndesmophyte formation in ankylosing spondylitis (AS) are yet to be characterised. Molecules involved in bone formation such as Wnt proteins and their antagonists probably drive syndesmophyte formation in AS. METHODS:This study investigated sequential serum levels of functiona...

    journal_title:Annals of the rheumatic diseases

    pub_type: 杂志文章

    doi:10.1136/annrheumdis-2011-200216

    authors: Heiland GR,Appel H,Poddubnyy D,Zwerina J,Hueber A,Haibel H,Baraliakos X,Listing J,Rudwaleit M,Schett G,Sieper J

    更新日期:2012-04-01 00:00:00

  • Symptomatic salicylate ototoxicity: a useful indicator of serum salicylate concentration?

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    journal_title:Annals of the rheumatic diseases

    pub_type: 杂志文章

    doi:10.1136/ard.50.10.682

    authors: Halla JT,Atchison SL,Hardin JG

    更新日期:1991-10-01 00:00:00

  • Research in hand osteoarthritis: time for reappraisal and demand for new strategies. An opinion paper.

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    journal_title:Annals of the rheumatic diseases

    pub_type: 杂志文章,meta分析

    doi:10.1136/ard.2007.070813

    authors: Kloppenburg M,Stamm T,Watt I,Kainberger F,Cawston TE,Birrell FN,Petersson IF,Saxne T,Kvien TK,Slatkowsky-Christensen B,Dougados M,Gossec L,Breedveld FC,Smolen JS

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  • A comparison of four shoulder-specific questionnaires in primary care.

    abstract:OBJECTIVES:To compare the validity, responsiveness to change, and user friendliness of four self completed, shoulder-specific questionnaires in primary care. METHODS:A cross sectional assessment of validity and a longitudinal assessment of responsiveness to change of four shoulder questionnaires was carried out: the D...

    journal_title:Annals of the rheumatic diseases

    pub_type: 杂志文章

    doi:10.1136/ard.2003.012088

    authors: Paul A,Lewis M,Shadforth MF,Croft PR,Van Der Windt DA,Hay EM

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  • Association of Epstein-Barr virus serological reactivation with transitioning to systemic lupus erythematosus in at-risk individuals.

    abstract:OBJECTIVE:Systemic lupus erythematosus (SLE) is a systemic autoimmune disease with unknown aetiology. Epstein-Barr virus (EBV) is an environmental factor associated with SLE. EBV maintains latency in B cells with frequent reactivation measured by antibodies against viral capsid antigen (VCA) and early antigen (EA). In ...

    journal_title:Annals of the rheumatic diseases

    pub_type: 杂志文章

    doi:10.1136/annrheumdis-2019-215361

    authors: Jog NR,Young KA,Munroe ME,Harmon MT,Guthridge JM,Kelly JA,Kamen DL,Gilkeson GS,Weisman MH,Karp DR,Gaffney PM,Harley JB,Wallace DJ,Norris JM,James JA

    更新日期:2019-09-01 00:00:00

  • Co-localisation of non-cartilaginous articular pathology increases risk of cartilage loss in the tibiofemoral joint--the MOST study.

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    journal_title:Annals of the rheumatic diseases

    pub_type: 杂志文章,多中心研究

    doi:10.1136/annrheumdis-2012-201810

    authors: Roemer FW,Felson DT,Wang K,Crema MD,Neogi T,Zhang Y,Nevitt MC,Marra MD,Lewis CE,Torner J,Guermazi A,MOST study investigators.

    更新日期:2013-06-01 00:00:00

  • The relationship between longitudinal serum leptin measures and measures of magnetic resonance imaging-assessed knee joint damage in a population of mid-life women.

    abstract:BACKGROUND AND OBJECTIVE:Serum leptin measures are associated with radiographic knee osteoarthritis, but no studies have examined leptin levels with respect to different measures of knee joint damage from MRI. METHODS:Participants in the Michigan Study of Women's Health Across the Nation underwent bilateral knee MRIs ...

    journal_title:Annals of the rheumatic diseases

    pub_type: 杂志文章

    doi:10.1136/annrheumdis-2012-202685

    authors: Karvonen-Gutierrez CA,Harlow SD,Jacobson J,Mancuso P,Jiang Y

    更新日期:2014-05-01 00:00:00

  • Isolation and growth characteristics of adult human tendon fibroblasts.

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    journal_title:Annals of the rheumatic diseases

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    doi:10.1136/ard.46.5.385

    authors: Chard MD,Wright JK,Hazleman BL

    更新日期:1987-05-01 00:00:00

  • Pyogenic osteomyelitis presenting as an acute sterile arthropathy.

    abstract::We report two cases of osteomyelitis secondary to staphylococcal septicaemia, presenting with large sterile effusions in adjacent joints. In both cases the clinical features were suggestive of septic arthritis. Multiple joints were involved in each patient. Initial radiographs showed no abnormalities. ...

    journal_title:Annals of the rheumatic diseases

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    doi:10.1136/ard.43.4.607

    authors: Platt PN,Griffiths ID

    更新日期:1984-08-01 00:00:00

  • Development of comprehensive disease assessment in systemic vasculitis.

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    journal_title:Annals of the rheumatic diseases

    pub_type: 杂志文章,评审

    doi:10.1136/ard.2005.051078

    authors: Flossmann O,Bacon P,de Groot K,Jayne D,Rasmussen N,Seo P,Westman K,Luqmani R

    更新日期:2007-03-01 00:00:00

  • Hydrostatic pressure induces expression of interleukin 6 and tumour necrosis factor alpha mRNAs in a chondrocyte-like cell line.

    abstract:OBJECTIVES:To clarify the effect of pressure on the expressions of proteoglycan core protein and metabolism related cytokines in a chondrocyte-like cell line, HCS-2/8. METHODS:HCS-2/8 cells were exposed to 1, 5, 10, or 50 MPa of hydrostatic pressure (HP) for two hours, and mRNA expressions of interleukin 6 (IL6) and t...

    journal_title:Annals of the rheumatic diseases

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    doi:10.1136/ard.57.4.231

    authors: Takahashi K,Kubo T,Arai Y,Kitajima I,Takigawa M,Imanishi J,Hirasawa Y

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    doi:10.1136/ard.2003.008516

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    doi:10.1136/ard.2006.059550

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    pub_type: 杂志文章,多中心研究,随机对照试验

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    authors: Glinatsi D,Baker JF,Hetland ML,Hørslev-Petersen K,Ejbjerg BJ,Stengaard-Pedersen K,Junker P,Ellingsen T,Lindegaard HM,Hansen I,Lottenburger T,Møller JM,Ørnbjerg L,Vestergaard A,Jurik AG,Thomsen HS,Torfing T,Møller-Bisgaa

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    journal_title:Annals of the rheumatic diseases

    pub_type: 临床试验,杂志文章,多中心研究,随机对照试验

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    authors: Sharp JT,Wolfe F,Corbett M,Isomaki H,Mitchell DM,Furst DE,Sibley J,Shipley M

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  • Responder analysis for pain relief and numbers needed to treat in a meta-analysis of etoricoxib osteoarthritis trials: bridging a gap between clinical trials and clinical practice.

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    pub_type: 杂志文章,meta分析

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