Clinical value of gallium-67 scintigraphy in assessment of disease activity in Wegener's granulomatosis.

abstract：OBJECTIVE:The expression of antinuclear antibodies (ANA) is considered almost constant in systemic lupus erythematosus (SLE), although recent experience has suggested that many subjects with SLE considered for clinical trials are ANA negative at screening. The objective of this study is to determine whether assay varia...

journal_title：Annals of the rheumatic diseases

authors： Pisetsky DS,Spencer DM,Lipsky PE,Rovin BH

更新日期：2018-06-01 00:00:00

abstract：BACKGROUND:The study aimed to evaluate the use of positron emission tomography/computed tomography (PET/CT) with (68)Ga-PRGD2 as the tracer for imaging of synovial angiogenesis in patients with rheumatoid arthritis (RA). METHODS:Twenty untreated active patients with RA underwent (68)Ga-PRGD2 PET/CT and (18)F-FDG PET/C...

journal_title：Annals of the rheumatic diseases

authors： Zhu Z,Yin Y,Zheng K,Li F,Chen X,Zhang F,Zhang X

更新日期：2014-06-01 00:00:00

abstract：OBJECTIVE:To compare three questions on knee pain with respect to determined prevalence and associations with disability and structural change. METHODS:Postal survey to 4057 men and women aged 40-79 years. Knee pain was defined by three questions: (A) "Have you ever had pain in or around the knee on most days for at l...

journal_title：Annals of the rheumatic diseases

authors： O'Reilly SC,Muir KR,Doherty M

更新日期：1996-12-01 00:00:00

abstract：OBJECTIVE:In the present work, the frequency of inherited polymorphisms of the beta2 adrenergic receptor (beta2AR) gene and their association with rheumatoid arthritis (RA) as well as human leukocyte antigen (HLA)-DRB1 alleles was examined. METHODS:An allele-specific polymerase chain reaction was used to determine the...

journal_title：Annals of the rheumatic diseases

authors： Malysheva O,Pierer M,Wagner U,Wahle M,Wagner U,Baerwald CG

更新日期：2008-12-01 00:00:00

abstract：:Neutrophil chemiluminescence was determined in patients with active rheumatoid arthritis. Twelve patients were randomly assigned either to a diet high in polyunsaturated fatty acids supplemented with eicosapentaenoic and docosahexaenoic acids or to a diet high in saturated fatty acids. A correlation with clinical and ...

journal_title：Annals of the rheumatic diseases

authors： Magaro M,Altomonte L,Zoli A,Mirone L,De Sole P,Di Mario G,Lippa S,Oradei A

更新日期：1988-10-01 00:00:00

abstract：OBJECTIVES:To evaluate the effect of infliximab on health related quality of life (HRQoL) and physical function in patients with active psoriatic arthritis (PsA) in the IMPACT 2 trial. METHODS:200 patients with PsA unresponsive to conventional treatment were randomised to intravenous infusions of infliximab 5 mg/kg or...

journal_title：Annals of the rheumatic diseases

authors： Kavanaugh A,Antoni C,Krueger GG,Yan S,Bala M,Dooley LT,Beutler A,Guzzo C,Gladman D

更新日期：2006-04-01 00:00:00

abstract：:Sheep red cells coated with rabbit IgG antibody may be used to detect IgM rheumatoid factors either by agglutination or microscopically by the fluorescence of antihuman IgM antibody conjugate bound to rheumatoid factors on the cell surface. By substituting for red cells the plastic surface of a filter disc coated with...

journal_title：Annals of the rheumatic diseases

authors： Lea DJ,Ward DJ

更新日期：1978-06-01 00:00:00

abstract：:Thirty-three patients with early peripheral synovitis were followed up for two to four years in order to study the relationship between fluctuations in rheumatoid factor (RF) levels and indices of clinical activity. Twenty-eight of these patients developed classical/definite rheumatoid arthritis (RA). Seventeen patien...

journal_title：Annals of the rheumatic diseases

authors： Withrington RH,Teitsson I,Valdimarsson H,Seifert MH

更新日期：1984-10-01 00:00:00

abstract：:A 15 year old girl who had pain, oedema of her left hand, and fever of four months' duration is described. Marked demineralisation of her hand was shown by radiography, and increased articular uptake by technetium-99m bone scan. All these changes were indistinguishable from reflex sympathetic dystrophy. After two admi...

journal_title：Annals of the rheumatic diseases

authors： Rodriguez-Moreno J,Ruiz-Martin JM,Mateo-Soria L,Rozadilla A,Roig-Escofet D

更新日期：1990-12-01 00:00:00

abstract：:The cellular events underlying the pathogenesis of psoriatic arthritis (PsA) and psoriasis have not yet been fully elucidated. Nevertheless, some clues to these conditions are beginning to emerge. In particular, a growing body of data supports the role of proinflammatory cytokines, such as tumour necrosis factor (TNF)...

journal_title：Annals of the rheumatic diseases

authors： Mease PJ

更新日期：2001-11-01 00:00:00

abstract：:Four hundred and forty unrelated British Caucasoid patients with rheumatoid arthritis (RA) have been HLA typed for class I and class II antigens. Analyses of HLA antigen associations were performed on the overall group and in patient subsets selected according to particular disease parameters or sex, or both. The resu...

journal_title：Annals of the rheumatic diseases

authors： Jaraquemada D,Ollier W,Awad J,Young A,Silman A,Roitt IM,Corbett M,Hay F,Cosh JA,Maini RN

更新日期：1986-08-01 00:00:00

abstract：OBJECTIVES:Smoking increases the risk of developing rheumatoid arthritis (RA) and worsens the course of the disease. In the current study we analysed whether smoking can affect gene expression directly in the joints. METHODS:Synovial fibroblasts were incubated with 5% cigarette smoke extract and changes in gene expres...

journal_title：Annals of the rheumatic diseases

authors： Ospelt C,Camici GG,Engler A,Kolling C,Vogetseder A,Gay RE,Michel BA,Gay S

更新日期：2014-07-01 00:00:00

abstract：:This review assesses the risk assessment of cardiovascular disease (CVD) in rheumatoid arthritis (RA) and how non-invasive imaging modalities may improve risk stratification in future. RA is common and patients are at greater risk of CVD than the general population. Cardiovascular (CV) risk stratification is recommend...

journal_title：Annals of the rheumatic diseases

authors： Fent GJ,Greenwood JP,Plein S,Buch MH

更新日期：2017-07-01 00:00:00

abstract：:Human extensor tendons of the hand were pulled to rupture, and the torn ends, when observed in the scanning electron microscope, appeared to be knotted, possibly owing to the denaturation of the collagen. This confirmed by fluorimetry assays of both the ruptured ends and the middle unbroken sections of the same tendon...

journal_title：Annals of the rheumatic diseases

authors： Minns RJ,Steven FS

更新日期：1980-04-01 00:00:00

abstract：OBJECTIVES:Antiphospholipid antibodies (aPLA) have been shown to enhance thrombus formation by increasing the expression of adhesive receptors such as P-selectin on endothelial cells. The P-selectin counter-receptor on leucocytes is P-selectin glycoprotein ligand-1 (PSGL-1). We have previously described a variable numb...

journal_title：Annals of the rheumatic diseases

authors： Diz-Kucukkaya R,Inanc M,Afshar-Kharghan V,Zhang QE,López JA,Pekcelen Y

更新日期：2007-10-01 00:00:00

abstract：:Naproxen at 10 mg per kg body weight was compared with aspirin at 80 mg per kg body weight in children suffering from juvenile chronic polyarthritis. It was found to be as effective as aspirin, with certainly no more and possibly fewer gastrointestinal side effects. A long-term tolerance study up to 12 months confirme...

journal_title：Annals of the rheumatic diseases

authors： Moran H,Hanna DB,Ansell BM,Hall M,Engler C

更新日期：1979-04-01 00:00:00

abstract：OBJECTIVE:Calprotectin is a major leucocyte protein, shown to correlate well with laboratory and clinical assessments in several inflammatory rheumatic diseases, and large concentrations of calprotectin have been found in synovial fluid from patients with rheumatoid arthritis (RA). The objective of the present study wa...

journal_title：Annals of the rheumatic diseases

authors： Hammer HB,Odegard S,Fagerhol MK,Landewé R,van der Heijde D,Uhlig T,Mowinckel P,Kvien TK

更新日期：2007-08-01 00:00:00

abstract：OBJECTIVE:Knee osteoarthritis commonly requires joint replacement, substantially reduces quality of life and increases healthcare utilisation and costs. This study aimed to identify whether quantitative measures of articular cartilage structure predict knee replacement, and to establish their utility as outcomes in cli...

journal_title：Annals of the rheumatic diseases

authors： Eckstein F,Kwoh CK,Boudreau RM,Wang Z,Hannon MJ,Cotofana S,Hudelmaier MI,Wirth W,Guermazi A,Nevitt MC,John MR,Hunter DJ,OAI investigators.

更新日期：2013-05-01 00:00:00

abstract：OBJECTIVE:In an unselected community sample of adults, to assess the role and importance of exposure to mechanical factors both at work and leisure in the aetiology of hip pain. METHOD:A population based prevalence case-control study. Cases and controls were identified from a population survey of 3847 subjects registe...

journal_title：Annals of the rheumatic diseases

authors： Pope DP,Hunt IM,Birrell FN,Silman AJ,Macfarlane GJ

更新日期：2003-04-01 00:00:00

abstract：:Eye disease, arthritis, folliculitis, and thrombophlebitis were more common among males, and erythema nodosum among females, in 297 patients with Behćet syndrome (BS) at their first visit despite an identical disease duration. Younger males and females (age of onset 24 years or less) had a higher prevalence of eye dis...

journal_title：Annals of the rheumatic diseases

authors： Yazici H,Tüzün Y,Pazarli H,Yurdakul S,Ozyazgan Y,Ozdoğan H,Serdaroğlu S,Ersanli M,Ulkü BY,Müftüoğlu AU

更新日期：1984-12-01 00:00:00

abstract：:Animals were injected intra-articularly with antigen after prior immunization with that antigen in Freund's incomplete adjuvant in order to precipitate immune complexes in the surfaces of menisci, ligaments, and cartilage. On reimmunization with antigen in Freund's complete adjuvant 10 weeks later, generally an arthri...

journal_title：Annals of the rheumatic diseases

authors： Fox A,Glynn LE

更新日期：1977-02-01 00:00:00

abstract：AIMS:The aim of this work was to assess the feasibility of using dynamic contrast enhanced (DCE) MRI of bone marrow oedema, to compare it with conventional marrow oedema scoring systems, and to determine the effects of anti-tumour necrosis factor (TNF)alpha therapy. METHODS:The wrist and metacarpophalangeal (MCP) join...

journal_title：Annals of the rheumatic diseases

authors： Hodgson R,Grainger A,O'Connor P,Barnes T,Connolly S,Moots R

更新日期：2008-02-01 00:00:00

abstract：:Monoclonal antibodies have proved to be extremely valuable additions to conventional treatment for rheumatic diseases. However, despite the general trend towards "humanisation", these drugs remain immunogenic in clinical settings, baffling drug developers. In principle, humanised and fully human monoclonal antibodies ...

journal_title：Annals of the rheumatic diseases

authors： Scott DW,De Groot AS

更新日期：2010-01-01 00:00:00

abstract：BACKGROUND:Analysis of salivary variables has frequently been proposed as a diagnostic tool for Sjögren's syndrome (SS). Because univocal salivary reference values are lacking, it is currently rather difficult to use sialometry and sialochemistry for diagnosing SS unless major changes have occurred in salivary secretio...

journal_title：Annals of the rheumatic diseases

authors： Kalk WW,Vissink A,Stegenga B,Bootsma H,Nieuw Amerongen AV,Kallenberg CG

更新日期：2002-02-01 00:00:00

abstract：BACKGROUND:Increased apoptosis may induce autoimmune conditions. Apoptosis is induced by binding of death receptor ligands, members of the tumour necrosis factor (TNF) superfamily, to their cognate receptors. The Fas-Fas ligand pathway has been studied extensively in relation to systemic lupus erythematosus (SLE). Howe...

journal_title：Annals of the rheumatic diseases

authors： Lub-de Hooge MN,de Vries EG,de Jong S,Bijl M

更新日期：2005-06-01 00:00:00

abstract：OBJECTIVE:To determine, using the method of adjusted indirect comparisons, whether there are differences in efficacy of tumour necrosis factor (TNF alpha) blocking agents, as measured by the rate ratios for American College of Rheumatology (ACR) 20, 50, and 70 responses, in patients with rheumatoid arthritis with an in...

journal_title：Annals of the rheumatic diseases

authors： Hochberg MC,Tracy JK,Hawkins-Holt M,Flores RH

更新日期：2003-11-01 00:00:00

abstract：:Treatment of rheumatoid arthritis (RA) may differ among rheumatologists and currently, clear and consensual international recommendations on RA treatment are not available. In this paper recommendations for the treatment of RA with synthetic and biological disease-modifying antirheumatic drugs (DMARDs) and glucocortic...

journal_title：Annals of the rheumatic diseases

authors： Smolen JS,Landewé R,Breedveld FC,Dougados M,Emery P,Gaujoux-Viala C,Gorter S,Knevel R,Nam J,Schoels M,Aletaha D,Buch M,Gossec L,Huizinga T,Bijlsma JW,Burmester G,Combe B,Cutolo M,Gabay C,Gomez-Reino J,Kouloumas M

更新日期：2010-06-01 00:00:00

abstract：OBJECTIVE:To compare the clinical, radiological, and biological profile of patients presenting late onset spondylarthropathy (LOSPA) with patients with early onset spondylarthropathy (EOSPA). METHODS:During the period April 1987 to April 1995 a retrospective chart review of inpatients and outpatients identified eight ...

journal_title：Annals of the rheumatic diseases

authors： Caplanne D,Tubach F,Le Parc JM

更新日期：1997-03-01 00:00:00

abstract：OBJECTIVES:The aim of this study was to determine if neutrophils isolated from the blood and synovial fluid of patients with rheumatoid arthritis had patterns of receptor expression resembling those of blood neutrophils from controls which had been activated and primed in vitro. METHODS:Fluorescence activated cell sor...

journal_title：Annals of the rheumatic diseases

authors： Watson F,Robinson JJ,Phelan M,Bucknall RC,Edwards SW

更新日期：1993-05-01 00:00:00

abstract：:Four patients with Neisseria meningitidis infection complicated by arthritis are described. Three patients had an acute polyarthritis which responded quickly to antimicrobial therapy. A fourth patient developed a prolonged arthritis which occurred after the initial infection had been successfully treated. Tenosynoviti...

journal_title：Annals of the rheumatic diseases

authors： Kidd BL,Hart HH,Grigor RR

更新日期：1985-11-01 00:00:00