Mutator transposons.

Abstract:

:Mutator (Mu) element insertion has become the main way of mutating and cloning maize genes, but we are only beginning to understand how this transposon system is regulated. Mu elements are under tight developmental control and are subject to a form of epigenetic regulation that shares some features with the regulation of paramutable maize genes. Mu-like elements (MULEs) are widespread among angiosperms, and multiple diverged functional variants appear to have coexisted in genomes for long periods. In addition to its utility, the means by which this widespread and highly mutagenic system is held in check should help us to address fundamental issues concerning the stability of genomes.

journal_name

Trends Plant Sci

journal_title

Trends in plant science

authors

Lisch D

doi

10.1016/s1360-1385(02)02347-6

subject

Has Abstract

pub_date

2002-11-01 00:00:00

pages

498-504

issue

11

eissn

1360-1385

issn

1878-4372

pii

S1360-1385(02)02347-6

journal_volume

7

pub_type

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