Abstract:
:The crop selection process has created a genetic bottleneck ultimately restricting breeding output. Wild relatives of major crops as well as the so-called 'neglected plant' species represent a reservoir of genetic diversity that remains underutilized. These species could be used as a tool to discover new alleles of agronomic interest or could be the target of breeding programs. Targeted induced local lesions in the genome (TILLING) can be used to translate in neglected crops what has been discovered in major crops and reciprocally. However, random mutagenesis, used in TILLING approaches, provides only a limited density of mutational events at a defined target locus. Alternatively, clustered regularly interspaced short palindromic repeats (CRISPR) associated 9 (Cas9) fused to a cytidine deaminase could serve as a localized mutagenic agent to produce high-density mutant populations. Artificial evolution is at hand.
journal_name
Trends Plant Scijournal_title
Trends in plant scienceauthors
Jacob P,Avni A,Bendahmane Adoi
10.1016/j.tplants.2017.10.002subject
Has Abstractpub_date
2018-01-01 00:00:00pages
42-52issue
1eissn
1360-1385issn
1878-4372pii
S1360-1385(17)30232-7journal_volume
23pub_type
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journal_title:Trends in plant science
pub_type: 杂志文章,评审
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journal_title:Trends in plant science
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journal_title:Trends in plant science
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journal_title:Trends in plant science
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journal_title:Trends in plant science
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journal_title:Trends in plant science
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journal_title:Trends in plant science
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journal_title:Trends in plant science
pub_type: 杂志文章,评审
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journal_title:Trends in plant science
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journal_title:Trends in plant science
pub_type: 评论,杂志文章
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journal_title:Trends in plant science
pub_type: 杂志文章,评审
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journal_title:Trends in plant science
pub_type: 杂志文章
doi:10.1016/j.tplants.2012.08.005
更新日期:2013-01-01 00:00:00
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journal_title:Trends in plant science
pub_type: 杂志文章,评审
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更新日期:2015-11-01 00:00:00
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journal_title:Trends in plant science
pub_type: 杂志文章,评审
doi:10.1016/j.tplants.2012.02.010
更新日期:2012-05-01 00:00:00
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journal_title:Trends in plant science
pub_type: 杂志文章,评审
doi:10.1016/j.tplants.2004.12.005
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pub_type: 杂志文章
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journal_title:Trends in plant science
pub_type: 杂志文章,评审
doi:10.1016/j.tplants.2012.04.006
更新日期:2012-08-01 00:00:00
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journal_title:Trends in plant science
pub_type: 杂志文章,评审
doi:10.1016/j.tplants.2003.08.003
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journal_title:Trends in plant science
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journal_title:Trends in plant science
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journal_title:Trends in plant science
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journal_title:Trends in plant science
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