Nonhalogenated anesthetic alkanes and perhalogenated nonimmobilizing alkanes inhibit alpha(4)beta(2) neuronal nicotinic acetylcholine receptors.

abstract：BACKGROUND:Hyperventilation has been an integral, but poorly validated part of neuroanesthetic practice. We conducted a two-period, crossover, randomized trial to evaluate surgeon-assessed brain bulk and measured intracranial pressure (ICP) in patients undergoing craniotomy for removal of supratentorial brain tumors du...

journal_title：Anesthesia and analgesia

authors： Gelb AW,Craen RA,Rao GS,Reddy KR,Megyesi J,Mohanty B,Dash HH,Choi KC,Chan MT

更新日期：2008-02-01 00:00:00

abstract：:Virchow's triad is traditionally invoked to explain pathophysiologic mechanisms leading to thrombosis, alleging concerted roles for abnormalities in blood composition, vessel wall components, and blood flow in the development of arterial and venous thrombosis. Given the tissue-specific bleeding observed in hemophilia ...

journal_title：Anesthesia and analgesia

authors： Wolberg AS,Aleman MM,Leiderman K,Machlus KR

更新日期：2012-02-01 00:00:00

abstract：:Neurotoxicity has been reported with tricyclic antidepressants (TCAs) used as local anesthetics. We examined the hypothesis that TCAs cause tissue injury, particularly myotoxicity, as occurs with many local anesthetics. Animals were given sciatic nerve injections with 0-80 mM doxepin, amitriptyline, or bupivacaine (1....

journal_title：Anesthesia and analgesia

authors： Barnet CS,Louis DN,Kohane DS

更新日期：2005-12-01 00:00:00

abstract：:We have recently reported a chronic allodynialike symptom in rats after ischemic spinal cord injury. This pain-related behavior is resistant to a number of pharmacologic treatments, including morphine, clonidine, carbamazepine, baclofen, and muscimol. In the present report, we present evidence indicating that systemic...

journal_title：Anesthesia and analgesia

authors： Xu XJ,Hao JX,Seiger A,Arnér S,Lindblom U,Wiesenfeld-Hallin Z

更新日期：1992-05-01 00:00:00

abstract：BACKGROUND:Unicondylar knee arthroplasty (UKA) is a commonly performed procedure with significant expected postoperative pain. Peripheral nerve blocks are 1 analgesic option, but some approaches may decrease quadriceps motor strength and interfere with early ambulation. In this study, we compared the analgesia provided...

journal_title：Anesthesia and analgesia

authors： Henshaw DS,Jaffe JD,Reynolds JW,Dobson S,Russell GB,Weller RS

更新日期：2016-04-01 00:00:00

abstract：:Our goal in this study was to develop a robotic intubation system and to conduct a feasibility pilot study on the use of a robotic intubation system for endotracheal intubations. The Kepler Intubation System was developed, consisting of a remote control center (joystick and intubation cockpit) linked to a standard vid...

journal_title：Anesthesia and analgesia

authors： Hemmerling TM,Wehbe M,Zaouter C,Taddei R,Morse J

更新日期：2012-03-01 00:00:00

abstract：:The antifibrinolytic drug, tranexamic acid, decreases blood loss in adult patients undergoing cardiac surgery. However, its efficacy has not been extensively studied in children. Using a prospective, randomized, double-blind study design, we examined 41 children undergoing repeat sternotomy for repair of congenital he...

journal_title：Anesthesia and analgesia

authors： Reid RW,Zimmerman AA,Laussen PC,Mayer JE,Gorlin JB,Burrows FA

更新日期：1997-05-01 00:00:00

abstract：UNLABELLED:We describe the development and evaluation of a simple slide rule that enables the bedside determination of the infusion rate for a particular target plasma concentration of propofol. The infusion rate to reach this target concentration at time (t) is the product of the target concentration, body weight, and...

journal_title：Anesthesia and analgesia

authors： Bruhn J,Bouillon TW,Röpcke H,Hoeft A

更新日期：2003-01-01 00:00:00

abstract：BACKGROUND:The proportion of live births by cesarean delivery (CD) in China is significant, with some, particularly rural, provinces reporting up to 62.5%. The No Pain Labor & Delivery-Global Health Initiative (NPLD-GHI) was established to improve obstetric and neonatal outcomes in China, including through a reduction ...

journal_title：Anesthesia and analgesia

authors： Drzymalski DM,Guo JC,Qi XQ,Tsen LC,Sun Y,Ouanes JP,Xia Y,Gao WD,Ruthazer R,Hu F,Hu LQ

更新日期：2020-04-22 00:00:00

abstract：BACKGROUND:Endoscopic retrograde cholangiopancreatography (ERCP) patients typically receive either tubeless anesthesia or general endotracheal anesthesia (GETA). Patients receiving propofol-based total intravenous anesthesia (TIVA) are at higher risk of sedation-related adverse events (SRAEs) than patients receiving GE...

journal_title：Anesthesia and analgesia

authors： Hagan KB,Carlson R,Arnold B,Nguyen L,Lee J,Weston B,Hernandez M,Feng L,Syed T,Hagberg CA

更新日期：2020-11-01 00:00:00

abstract：UNLABELLED:Hypothermia after induction of general anesthesia results largely from core-to-peripheral redistribution of body heat. Both central inhibition of tonic thermoregulatory vasoconstriction in arteriovenous shunts and anesthetic-induced arteriolar and venous dilation contribute to this redistribution. Ketamine, ...

journal_title：Anesthesia and analgesia

authors： Ikeda T,Kazama T,Sessler DI,Toriyama S,Niwa K,Shimada C,Sato S

更新日期：2001-10-01 00:00:00

abstract：:Lidocaine and MgSO4 are often coadministered to patients with pregnancy-induced hypertension. This study examined whether MgSO4 alters the lidocaine-seizure threshold in the rat and, if so, whether systemic MgSO4 administration is as effective as intracerebroventricular MgSO4 infusion. In Experiment 1, rats were admin...

journal_title：Anesthesia and analgesia

authors： Kim YJ,McFarlane C,Warner DS,Baker MT,Choi WW,Dexter F

更新日期：1996-12-01 00:00:00

abstract：UNLABELLED:In this study, we tested the validity of the bispectral index (BIS) monitor during conscious and deep sedation of children by comparing it with the University of Michigan Sedation Scale (UMSS), a validated observational pediatric sedation scale. Eighty-six children <12 yr of age were enrolled in this observa...

journal_title：Anesthesia and analgesia

authors： McDermott NB,VanSickle T,Motas D,Friesen RH

更新日期：2003-07-01 00:00:00

abstract：UNLABELLED:Obese surgical patients are typically considered to be more likely than lean patients to possess high-volume and low-pH (HVLP) gastric contents after a standard preoperative fast, based on a study of a population predominately consisting of patients receiving intramuscular preoperative sedation. We revisited...

journal_title：Anesthesia and analgesia

authors： Harter RL,Kelly WB,Kramer MG,Perez CE,Dzwonczyk RR

更新日期：1998-01-01 00:00:00

abstract：:Delirium is an acute change in cognition and attention, which may include alterations in consciousness and disorganized thinking. Although delirium may affect any age group, it is most common in older patients, especially those with preexisting cognitive impairment. Patients with delirium after surgery recover more sl...

journal_title：Anesthesia and analgesia

authors： Rudolph JL,Marcantonio ER

更新日期：2011-05-01 00:00:00

abstract：:We tested whether anesthesia that includes nitrous oxide (N2O) results in the development of intraoperative and postoperative pulmonary complications, including hypoxemia. We also tested whether aging contributes to the development of such complications, particularly when anesthesia includes N2O. We randomly allocated...

journal_title：Anesthesia and analgesia

authors： Lampe GH,Wauk LZ,Whitendale P,Way WL,Kozmary SV,Donegan JH,Eger EI 2nd

更新日期：1990-12-01 00:00:00

abstract：BACKGROUND:Women laboring with epidural analgesia experience fever much more frequently than do women who chose other forms of analgesia, and maternal intrapartum fever is associated with numerous adverse consequences, including brain injury in the fetus. We developed a model of noninfectious inflammatory fever in the ...

journal_title：Anesthesia and analgesia

authors： Segal S,Pancaro C,Bonney I,Marchand JE

更新日期：2017-12-01 00:00:00

abstract：:This retrospective case series of patients with refractory sacroiliac joint (SIJ) pain presents our first 77 SIJ radiofrequency ablation (RFA) procedures performed with a multilesion probe. Of these, 16 (20.8%) provided no relief; 55 (71.4%) provided >50% pain relief at 6 weeks; 42 (54.5%, 95% confidence interval, 42....

journal_title：Anesthesia and analgesia

authors： Schmidt PC,Pino CA,Vorenkamp KE

更新日期：2014-08-01 00:00:00

abstract：UNLABELLED:We investigated the impact of cardiopulmonary bypass pump (CPB), hematocrit, gender, age, and body weight on blood use in patients undergoing coronary artery bypass graft surgery at a major university hospital. Participants were 1235 consecutive patients undergoing primary coronary artery surgery over a peri...

journal_title：Anesthesia and analgesia

authors： Scott BH,Seifert FC,Glass PS,Grimson R

更新日期：2003-10-01 00:00:00

abstract：:Epidural catheter placement offers flexibility in block management. However, during epidural catheter insertion, complications such as paresthesia and venous and subarachnoid cannulation may occur, and suboptimal catheter placement can affect the quality of anesthesia. We performed this prospective, randomized, double...

journal_title：Anesthesia and analgesia

authors： Cesur M,Alici HA,Erdem AF,Silbir F,Yuksek MS

更新日期：2005-11-01 00:00:00

abstract：UNLABELLED:Propofol and thiopental have been used clinically in combination for induction of anesthesia. Studies suggest that this mixture has synergistic activity, recovery characteristics similar to propofol alone, and bactericidal effects on multiple organisms. It may therefore be both clinically useful and cost-eff...

journal_title：Anesthesia and analgesia

authors： Lazar ER,Jolly DT,Tam YK,Hrazdil J,Tawfik SR,Clanachan AS

更新日期：1998-02-01 00:00:00

abstract：BACKGROUND:Continuous femoral analgesia provides extended pain relief and improved functional recovery for total knee arthroplasty (TKA). Stimulating catheters may allow more accurate placement of catheters. METHODS:We performed a randomized prospective study to investigate the use of stimulating catheters versus nons...

journal_title：Anesthesia and analgesia

authors： Hayek SM,Ritchey RM,Sessler D,Helfand R,Samuel S,Xu M,Beven M,Bourdakos D,Barsoum W,Brooks P

更新日期：2006-12-01 00:00:00

abstract：UNLABELLED:Shoulder surgery is often performed with patients in the sitting position under interscalene block anesthesia. Vasovagal episodes, characterized by a sudden decrease in heart rate and/or blood pressure, have a reported incidence of 17%-24% in this setting. We performed a retrospective study to determine whet...

journal_title：Anesthesia and analgesia

authors： Kahn RL,Hargett MJ

更新日期：1999-02-01 00:00:00

abstract：:Although amrinone produces thrombocytopenia, no information is available regarding the acute effects of milrinone on platelets. Therefore, we evaluated the effects of milrinone on platelet number and function in cardiac surgical patients. Twenty-seven patients were studied during cardiac surgery requiring cardiopulmon...

journal_title：Anesthesia and analgesia

authors： Kikura M,Lee MK,Safon RA,Bailey JM,Levy JH

更新日期：1995-07-01 00:00:00

abstract：:Alfentanil causes cardiac stimulation or depression in intact animals and in clinical practice; there is no information concerning its direct effects on the heart. Therefore, we studied the effects of alfentanil on isolated cardiac tissues from young adult rabbits. The right atrium with sinoatrial node (SA node) was b...

journal_title：Anesthesia and analgesia

authors： Zhang CC,Su JY,Calkins D

更新日期：1990-09-01 00:00:00

abstract：:The extent and magnitude of sympathetic blockade during epidural anesthesia have previously been assessed only by indirect methods. In this study, direct intraneural recordings of muscle sympathetic activity (MSA) in the peroneal nerve was performed to determine the profundity of blockade of sympathetic fibers to the ...

journal_title：Anesthesia and analgesia

authors： Lundin S,Wallin BG,Elam M

更新日期：1989-12-01 00:00:00

abstract：UNLABELLED:Fentanyl reduces the amount of propofol necessary to prevent responses to surgical stimuli. However, opioids have relatively little effect on consciousness. We, therefore, tested the hypothesis that fentanyl minimally alters the effect-site concentration of propofol associated with awakening. Fifty women hav...

journal_title：Anesthesia and analgesia

authors： Iwakiri H,Nagata O,Matsukawa T,Ozaki M,Sessler DI

更新日期：2003-06-01 00:00:00

abstract：IMPLICATIONS:Because of case reports of severe bronchospasm after the use of mivacurium, we used the Food and Drug Administration MedWatch database to determine the frequency of bronchospasm as an adverse event after the use of nondepolarizing muscle relaxants. ...

journal_title：Anesthesia and analgesia

authors： Bishop MJ,O'Donnell JT,Salemi JR

更新日期：2003-08-01 00:00:00

abstract：:The present investigation explored the possibility that the commonly observed hypotension that occurs during induction of anesthesia with propofol might be related to its ability to produce venodilation. Thirty-six ASA I and II patients who received no premedication were studied. The first 20 patients were divided int...

journal_title：Anesthesia and analgesia

authors： Muzi M,Berens RA,Kampine JP,Ebert TJ

更新日期：1992-06-01 00:00:00

abstract：BACKGROUND:We have developed a proportional-integral-derivative controller allowing the closed-loop coadministration of propofol and remifentanil, guided by a Bispectral Index (BIS) monitor, during induction and maintenance of general anesthesia. The controller was compared with manual target-controlled infusion. METH...

journal_title：Anesthesia and analgesia

authors： Liu N,Chazot T,Hamada S,Landais A,Boichut N,Dussaussoy C,Trillat B,Beydon L,Samain E,Sessler DI,Fischler M

更新日期：2011-03-01 00:00:00