Infectious risks and outcomes after stem cell transplantation: are nonmyeloablative transplants changing the picture?

abstract：PURPOSE OF REVIEW:To consider new treatment options for cytomegalovirus (CMV) infection, review recent trials, and anticipate their use in clinical practice, focussing on bone marrow transplantation, congenital infection, and intervention during pregnancy. RECENT FINDINGS:Three double-blind randomized placebo-controll...

journal_title：Current opinion in infectious diseases

authors： Griffiths P,Lumley S

更新日期：2014-12-01 00:00:00

abstract：PURPOSE OF REVIEW:Associations between processes of care for hospitalized community-acquired pneumonia patients and clinical outcomes are important because of the high incidence of such admissions and substantial related mortality. Several studies have examined these associations. RECENT FINDINGS:Large retrospective s...

journal_title：Current opinion in infectious diseases

authors： Houck PM,Bratzler DW

更新日期：2005-04-01 00:00:00

abstract：PURPOSE OF REVIEW:Ventilator-associated pneumonia (VAP) is the most frequent cause of death among the nosocomial infections acquired in the ICU. Routine surveillance endotracheal aspirate (ETA) cultures in patients on mechanical ventilation have been proposed to predict the cause of VAP. Our aim is to review the availa...

journal_title：Current opinion in infectious diseases

authors： Luna CM,Bledel I,Raimondi A

更新日期：2014-04-01 00:00:00

abstract：PURPOSE OF REVIEW:Skin and soft tissue infections (SSTIs) in patients with hematological malignancies are frequent, but dedicated epidemiological studies are limited. The aim of this review is to provide updated description of the main etiological agents, differential diagnosis, and treatment. RECENT FINDINGS:In addit...

journal_title：Current opinion in infectious diseases

authors： Ungaro R,Mikulska M

更新日期：2020-04-01 00:00:00

abstract：PURPOSE OF REVIEW:Antibiotic resistance continues to rise, whereas development of new agents to counter it has slowed. A heightened need exists to maintain the effectiveness of currently available agents. This review focuses on the need for better antimicrobial stewardship, expected benefits of well designed antimicrob...

journal_title：Current opinion in infectious diseases

authors： Goff DA

更新日期：2011-02-01 00:00:00

abstract：PURPOSE OF REVIEW:This review focuses on recent developments on evaluation of 8-aminoquinoline analogs with broader efficacy and reduced toxicity, which would provide better drugs for treatment of protozoal infections. RECENT FINDINGS:The earlier efforts towards development of 8-aminoquinoline analogs have been direct...

journal_title：Current opinion in infectious diseases

authors： Tekwani BL,Walker LA

更新日期：2006-12-01 00:00:00

abstract：PURPOSE OF REVIEW:Early treatment of invasive mold infections improves the outcome. Therapy is often delayed, however, because available diagnostic tools such as culture, microscopy and conventional radiology lack sensitivity; consequently, empirical initiation of antifungal therapy has been advocated, particularly for...

journal_title：Current opinion in infectious diseases

authors： Maertens J,Deeren D,Dierickx D,Theunissen K

更新日期：2006-12-01 00:00:00

abstract：PURPOSE OF REVIEW:The aim is to describe and quantify the association between genitourinary tract infections and preterm birth. RECENT FINDINGS:Recent studies confirm the importance of identifying and treating both asymptomatic and symptomatic bacteriuria in pregnancy, which is reflected in current antenatal screening...

journal_title：Current opinion in infectious diseases

authors： Cunnington M,Kortsalioudaki C,Heath P

更新日期：2013-06-01 00:00:00

abstract：PURPOSE OF REVIEW:HIV postexposure prophylaxis is often recommended following potential sexual exposure to HIV. Recent data address the effectiveness of postexposure prophylaxis and prevention counseling, cost-effectiveness, antiretroviral options, challenges with nonoccupational postexposure prophylaxis among adolesce...

journal_title：Current opinion in infectious diseases

authors： Roland ME

更新日期：2007-02-01 00:00:00

abstract：PURPOSE OF REVIEW:This review addresses recent developments that relate to the pathogenesis of severe malaria and its treatment, and also highlights the increase in the global burden of malaria and provides a summary of clinical trials of malaria vaccines. RECENT FINDINGS:Malaria, one of the world's most important par...

journal_title：Current opinion in infectious diseases

authors： Maitland K,Bejon P,Newton CR

更新日期：2003-10-01 00:00:00

abstract：PURPOSE OF REVIEW:Hidradenitis suppurativa is a chronic or relapsing inflammatory cutaneous disorder manifested by recurrent formation of abscesses, fistulating sinus and scarring in the apocrine-gland-bearing skin. This review discusses the different aetiological theories and management opportunities. RECENT FINDINGS...

journal_title：Current opinion in infectious diseases

authors： Yazdanyar S,Jemec GB

更新日期：2011-04-01 00:00:00

abstract：PURPOSE OF REVIEW:The aim is to evaluate basic mechanisms, prevalence, risk factors, outcomes, and potential treatments of cardiovascular events (CVEs) in patients with community-acquired pneumonia (CAP). RECENT FINDINGS:In this review, we present a new model to evaluate the pathophysiology of cardiac disease in patie...

journal_title：Current opinion in infectious diseases

authors： Aliberti S,Ramirez JA

更新日期：2014-06-01 00:00:00

abstract：PURPOSE OF REVIEW:The majority of hepatitis C virus (HCV) infections in the United Kingdom and many developing countries were acquired through injecting. New clinical guidance suggests that HCV treatment should be offered to people with a transmission risk - such as people who inject drugs (PWID) - irrespective of seve...

journal_title：Current opinion in infectious diseases

authors： Hickman M,De Angelis D,Vickerman P,Hutchinson S,Martin NK

更新日期：2015-12-01 00:00:00

abstract：PURPOSE OF REVIEW:Bronchiectasis is an under-appreciated cause of chronic lung disease in the USA. We highlight developments in diagnosis and treatment of this debilitating disease. RECENT FINDINGS:A possible link between gastroesophageal reflux and development of nontuberculous mycobacterial lung disease was highligh...

journal_title：Current opinion in infectious diseases

authors： Ilowite J,Spiegler P,Chawla S

更新日期：2008-04-01 00:00:00

abstract：:The subject of bacterial skin infection in the tropics has shown some significant advances in the past few years, although it is still relatively understudied. Of special interest is the emerging concern about the public health aspects of pyoderma, either primary or secondary to scabies, in developing countries. In ad...

journal_title：Current opinion in infectious diseases

authors： Mahé A

更新日期：2001-04-01 00:00:00

abstract：PURPOSE OF REVIEW:Several studies show that the number of FcgammaRI (CD64) on the surface of neutrophils increases in infections. However, in spite of increased research interest in recent years, there is no clear general view on the usability of neutrophil FcgammaRI in clinical infection diagnostics. This review tries...

journal_title：Current opinion in infectious diseases

authors： Nuutila J

更新日期：2010-06-01 00:00:00

abstract：:Cystic fibrosis is the most common lethal inherited disorder with autosomal recessive inheritance. Major progress has been made in understanding the molecular mechanisms leading to increased susceptibility to Pseudomonas aeruginosa colonization. Persistent respiratory infection with P. aeruginosa leads to progressive ...

journal_title：Current opinion in infectious diseases

authors： Brennan AL,Geddes DM

更新日期：2002-04-01 00:00:00

abstract：PURPOSE OF REVIEW:Chronic pulmonary aspergillosis (CPA) is a relatively rare, slowly progressive pulmonary syndrome due to Aspergillus spp. that requires specific knowledge in terms of disease entity, diagnosis, management and azole resistance. This review focuses on the recent understanding of CPA entity and the emerg...

journal_title：Current opinion in infectious diseases

authors： Izumikawa K,Takazono T,Kohno S

更新日期：2010-12-01 00:00:00

abstract：PURPOSE OF REVIEW:West Nile virus emerged recently in North America as a serious human and animal pathogen. This review summarizes the use of experimental infections with West Nile virus in diverse vertebrate species that have been used to answer fundamental questions about the host response, pathogenesis of West Nile ...

journal_title：Current opinion in infectious diseases

authors： Bowen RA,Nemeth NM

更新日期：2007-06-01 00:00:00

abstract：PURPOSE OF REVIEW:In hematopoietic cell transplant (HCT) recipients, paramyxovirus infections are major viral respiratory tract infections that, if they progress to lower respiratory tract infections, are associated with reduced survival rates in this population. There are important knowledge gaps regarding treatment d...

journal_title：Current opinion in infectious diseases

authors： Batista MV,El Haddad L,Chemaly RF

更新日期：2018-12-01 00:00:00

abstract：:Although the association remains controversial, enteroviruses have been implicated in the aetiology of several chronic diseases in humans. Investigations in vitro lead to better understanding of virus-cell interactions, and improve our knowledge of the molecular factors that are involved in the establishment and maint...

journal_title：Current opinion in infectious diseases

authors： Frisk G

更新日期：2001-06-01 00:00:00

abstract：PURPOSE OF REVIEW:New respiratory viruses have been discovered in recent years and new molecular diagnostic assays have been developed that improve our understanding of respiratory virus infections. This article will review the changing epidemiology of these viruses after hematopoietic stem cell and solid organ transpl...

journal_title：Current opinion in infectious diseases

authors： Renaud C,Campbell AP

更新日期：2011-08-01 00:00:00

abstract：PURPOSE OF REVIEW:Streptococcus pneumoniae is a major cause of morbidity and mortality in the pediatric population. The development of increasing resistance to multiple classes of antibiotics is making treatment of infections due to this organism much more difficult. The ultimate impact of high-level antibiotic resista...

journal_title：Current opinion in infectious diseases

authors： Tan TQ

更新日期：2003-06-01 00:00:00

abstract：PURPOSE OF REVIEW:There is a global need for well tolerated, effective, and affordable vaccines to prevent group A streptococcal infections and their most serious complications. The aim of this review is to highlight the recent progress in the identification of promising vaccine antigens and new approaches to vaccine d...

journal_title：Current opinion in infectious diseases

authors： Dale JB,Walker MJ

更新日期：2020-06-01 00:00:00

abstract：PURPOSE OF REVIEW:Bacterial zoonoses are increasingly described in association with travel. Some bacterial zoonoses constitute important causes of post-travel illness. We focus on leptospirosis and rickettsiosis - the most common travel-associated bacterial zoonoses. RECENT FINDINGS:Leptospirosis is regarded to be the...

journal_title：Current opinion in infectious diseases

authors： Leshem E,Meltzer E,Schwartz E

更新日期：2011-10-01 00:00:00

abstract：PURPOSE OF REVIEW:Migrants living in high-income countries are disproportionately affected by HIV infection and frequently have characteristics associated with poor HIV clinical outcomes. HIV epidemiology among migrants is influenced by changes in migration patterns and variations in transmission risk behaviors. Here w...

journal_title：Current opinion in infectious diseases

authors： Ross J,Cunningham CO,Hanna DB

更新日期：2018-02-01 00:00:00

abstract：PURPOSE OF REVIEW:The purpose of this review is to assess the recent studies of therapy of pregnant women and neonates, aimed at preventing the consequences of congenital cytomegalovirus (CMV) infection. RECENT FINDINGS:A recent randomized controlled trial of treatment of CMV during pregnancy with hyperimmune globulin...

journal_title：Current opinion in infectious diseases

authors： Rawlinson WD,Hamilton ST,van Zuylen WJ

更新日期：2016-12-01 00:00:00

abstract：PURPOSE OF REVIEW:Human brucellosis is a neglected, underrecognized infection of widespread geographic distribution. It causes acute febrile illness and a potentially debilitating chronic infection in humans, and livestock infection has substantial socioeconomic impact. This review describes new information regarding t...

journal_title：Current opinion in infectious diseases

authors： Rubach MP,Halliday JE,Cleaveland S,Crump JA

更新日期：2013-10-01 00:00:00

abstract：:Development of vaccines against viral haemorrhagic fevers is a public health priority. Recent advances in our knowledge of pathogenesis and of the immune responses elicited by these viruses emphasize the crucial role of the immune system in the control of infection, but also its probable involvement in pathogenesis. S...

journal_title：Current opinion in infectious diseases

authors： Baize S,Marianneau P,Georges-Courbot MC,Deubel V

更新日期：2001-10-01 00:00:00

abstract：:Therapeutic approaches in the practice of haematology/oncology are increasing in complexity. Agents such as the purine analogues and monoclonal antibodies may introduce a new spectrum of infection as a consequence of prolonged/profound lymphoid suppression. The use of high dose therapy with stem cells support is incre...

journal_title：Current opinion in infectious diseases

authors： Potter M

更新日期：1999-08-01 00:00:00