A six year prospective study of a cohort of patients with fibromyalgia.

abstract：:Of 60 patients with rheumatoid arthritis treated with levamisole 35% showed a persistent decrease in neutrophil counts from pre-treatment levels and 6 (10%) develped severe neutropenia of less than 1.0 X 10(9)/1. One of these neutropenic patients recoverd without stopping therapy and the other 5 patients recovered rap...

journal_title：Annals of the rheumatic diseases

authors： Williams GT,Johnson SA,Dieppe PA,Huskisson EC

更新日期：1978-08-01 00:00:00

abstract：OBJECTIVE:A systematic literature review (SLR; 2009-2014) to compare a target-oriented approach with routine management in the treatment of rheumatoid arthritis (RA) to allow an update of the treat-to-target recommendations. METHODS:Two SLRs focused on clinical trials employing a treatment approach targeting a specifi...

journal_title：Annals of the rheumatic diseases

authors： Stoffer MA,Schoels MM,Smolen JS,Aletaha D,Breedveld FC,Burmester G,Bykerk V,Dougados M,Emery P,Haraoui B,Gomez-Reino J,Kvien TK,Nash P,Navarro-Compán V,Scholte-Voshaar M,van Vollenhoven R,van der Heijde D,Stamm TA

更新日期：2016-01-01 00:00:00

abstract：:Naproxen at 10 mg per kg body weight was compared with aspirin at 80 mg per kg body weight in children suffering from juvenile chronic polyarthritis. It was found to be as effective as aspirin, with certainly no more and possibly fewer gastrointestinal side effects. A long-term tolerance study up to 12 months confirme...

journal_title：Annals of the rheumatic diseases

authors： Moran H,Hanna DB,Ansell BM,Hall M,Engler C

更新日期：1979-04-01 00:00:00

abstract：OBJECTIVE:To determine whether the number of patients required in a therapeutic trial that uses progression of radiological abnormalities as the outcome measure would be similar for multiple centres. METHODS:The progression of radiological damage to the fingers and wrists of patients with rheumatoid arthritis in five ...

journal_title：Annals of the rheumatic diseases

authors： Sharp JT,Wolfe F,Corbett M,Isomaki H,Mitchell DM,Furst DE,Sibley J,Shipley M

更新日期：1993-05-01 00:00:00

abstract：OBJECTIVE:To examine the association between body mass index (BMI) and osteoarthritis (OA) leading to total hip (THR) or knee (TKR) joint replacement. METHODS:Case-control study design. All patients still living in Iceland who had had a THR or TKR resulting from OA before the end of 2002 were invited to participate. F...

journal_title：Annals of the rheumatic diseases

authors： Franklin J,Ingvarsson T,Englund M,Lohmander LS

更新日期：2009-04-01 00:00:00

abstract：OBJECTIVE:To assess the effects of acute stress on inflammatory, haemostatic, rheological, and haemodynamic activity in patients with rheumatoid arthritis (RA) in comparison with patients with osteoarthritis (OA). METHODS:21 patients with RA and 10 with OA underwent a brief mental stress task while standing. Inflammat...

journal_title：Annals of the rheumatic diseases

authors： Veldhuijzen van Zanten JJ,Ring C,Carroll D,Kitas GD

更新日期：2005-09-01 00:00:00

abstract：OBJECTIVE:To determine whether 17beta-oestradiol (E2) modulates interleukin (IL) 1beta-induced proteoglycan degradation in chondrocytes, and to analyse the part played by metalloproteinases (MMPs) in this process. METHODS:Primary cultured rabbit articular chondrocytes were prepared and treated with 10 ng/ml IL1beta co...

journal_title：Annals of the rheumatic diseases

authors： Richette P,Dumontier MF,François M,Tsagris L,Korwin-Zmijowska C,Rannou F,Corvol MT

更新日期：2004-02-01 00:00:00

abstract：:Fourteen patients with cystic fibrosis arthritis and eight patients with cystic fibrosis and hypertrophic osteoarthropathy were typed for HLA-A, B, C, DR, and DQ antigens and were compared with age and sex matched controls with cystic fibrosis. The diagnosis of cystic fibrosis arthritis and hypertrophic osteoarthropat...

journal_title：Annals of the rheumatic diseases

authors： Rush PJ,Gladman DD,Shore A,Anhorn KA

更新日期：1991-11-01 00:00:00

abstract：BACKGROUND:Antenatal and postnatal treatment with dexamethasone (DEX) may negatively affect the neuropsychological development in children. Maternal anti-Ro/Sjögren's syndrome A (SSA) antibodies may also be associated with learning disabilities in offspring. OBJECTIVE:To assess neuropsychological development in babies...

journal_title：Annals of the rheumatic diseases

authors： Brucato A,Astori MG,Cimaz R,Villa P,Li Destri M,Chimini L,Vaccari R,Muscarà M,Motta M,Tincani A,Neri F,Martinelli S

更新日期：2006-11-01 00:00:00

abstract：:IgM rheumatoid factor (RF) was measured in the sera of 48 rheumatoid patients and of 48 age and sex-matched normal controls by the Rose-Waaler and latex agglutination tests, a rate nephelometer, and an enzyme-linked immunosorbent assay (ELISA). Good correlation was obtained between all assays. The rate nephelometer as...

journal_title：Annals of the rheumatic diseases

authors： Bampton JL,Cawston TE,Kyle MV,Hazleman BL

更新日期：1985-01-01 00:00:00

abstract：BACKGROUND:Although natural regulatory T cells (nTregs) can suppress osteoclastogenesis, the role of TGF-β-induced CD4+Foxp3+ Tregs (iTregs) in osteoclastogenesis remains unknown. OBJECTIVE:To determine the effects of iTregs on osteoclastogenesis in vitro and on bone erosion in vivo in collagen-induced arthritis (CIA)...

journal_title：Annals of the rheumatic diseases

authors： Kong N,Lan Q,Su W,Chen M,Wang J,Yang Z,Park R,Dagliyan G,Conti PS,Brand D,Liu Z,Stohl W,Zou H,Zheng SG

更新日期：2012-09-01 00:00:00

abstract：OBJECTIVES:Increased numbers of neutrophils expressing proteinase 3 on their membrane (mPR3) have been reported in anti-neutrophil cytoplasm antibody (ANCA)-associated vasculitis (AAV) and are suggested to be involved in AAV immunopathogenesis. In most studies, neutrophils were analysed for mPR3 expression without prim...

journal_title：Annals of the rheumatic diseases

authors： van Rossum AP,Huitema MG,Stegeman CA,Bijl M,de Leeuw K,Van Leeuwen MA,Limburg PC,Kallenberg CG

更新日期：2007-10-01 00:00:00

abstract：:Hereditary deficiencies of early complement components have usually been associated with the development of rheumatic diseases like systemic lupus erythematosus (SLE), while terminal component deficiency is well known to predispose to recurrent neisserial infection. In contrast, only recently have patients been report...

journal_title：Annals of the rheumatic diseases

authors： Wisnieski JJ,Naff GB,Pensky J,Sorin SB

更新日期：1985-10-01 00:00:00

abstract：BACKGROUND:Preliminary clinical criteria based on age, inflammation, and immobility have been proposed to identify which patients with rheumatoid arthritis (RA) should be examined by dual energy x ray absorptiometry (DXA) to diagnose osteoporosis. The three item criteria have not been evaluated in male patients with RA...

journal_title：Annals of the rheumatic diseases

authors： Haugeberg G,Ørstavik RE,Uhlig T,Falch JA,Halse JI,Kvien TK

更新日期：2002-12-01 00:00:00

abstract：OBJECTIVE:To compare the performance of the American-European Consensus Group (AECG) and the newly proposed American College of Rheumatology (ACR) classification criteria for Sjögren's Syndrome (SS) in a well-characterised sicca cohort, given ongoing efforts to resolve discrepancies and weaknesses in the systems. METH...

journal_title：Annals of the rheumatic diseases

authors： Rasmussen A,Ice JA,Li H,Grundahl K,Kelly JA,Radfar L,Stone DU,Hefner KS,Anaya JM,Rohrer M,Gopalakrishnan R,Houston GD,Lewis DM,Chodosh J,Harley JB,Hughes P,Maier-Moore JS,Montgomery CG,Rhodus NL,Farris AD,Segal BM

更新日期：2014-01-01 00:00:00

abstract：OBJECTIVES:Systemic sclerosis (SSc) is a rare disease requiring multicentre collaboration to reveal comprehensive details of disease-related causes for morbidity and mortality. METHODS:The European League Against Rheumatism (EULAR) Scleroderma Trials and Research (EUSTAR) group initiated a database to prospectively ga...

journal_title：Annals of the rheumatic diseases

authors： Meier FM,Frommer KW,Dinser R,Walker UA,Czirjak L,Denton CP,Allanore Y,Distler O,Riemekasten G,Valentini G,Müller-Ladner U,EUSTAR Co-authors.

更新日期：2012-08-01 00:00:00

abstract：OBJECTIVE:To elucidate the clinical importance of the anti-signal recognition particle (SRP) autoantibody in patients with myositis. METHODS:Retrospective systematic assessment of the clinical, laboratory and histological characteristics of 23 anti-SRP-positive patients from six European centres. Data were compared wi...

journal_title：Annals of the rheumatic diseases

authors： Hengstman GJ,ter Laak HJ,Vree Egberts WT,Lundberg IE,Moutsopoulos HM,Vencovsky J,Doria A,Mosca M,van Venrooij WJ,van Engelen BG

更新日期：2006-12-01 00:00:00

abstract：OBJECTIVE:To elaborate a clinical practice decision tree for the choice of the first disease modifying antirheumatic drug (DMARD) for untreated rheumatoid arthritis of less than six months' duration. METHODS:Four steps were employed: (1) review of published reports on DMARD efficacy against rheumatoid arthritis; (2) i...

journal_title：Annals of the rheumatic diseases

authors： Le Loët X,Berthelot JM,Cantagrel A,Combe B,De Bandt M,Fautrel B,Flipo RM,Lioté F,Maillefert JF,Meyer O,Saraux A,Wendling D,Guillemin F

更新日期：2006-01-01 00:00:00

abstract：OBJECTIVE:To evaluate the gastrointestinal safety and efficacy of the COX inhibiting nitric oxide donator AZD3582 in patients with hip or knee osteoarthritis. METHODS:970 patients were randomised (7:7:2) to AZD3582 750 mg twice daily, naproxen 500 mg twice daily, or placebo twice daily in a double blind study. The pri...

journal_title：Annals of the rheumatic diseases

authors： Lohmander LS,McKeith D,Svensson O,Malmenäs M,Bolin L,Kalla A,Genti G,Szechinski J,Ramos-Remus C,STAR Multinational Study Group.

更新日期：2005-03-01 00:00:00

abstract：BACKGROUND:Osteoarthritis of the hands is a prevalent musculoskeletal disease with a considerable effect on patients' lives, but knowledge and research results in the field of hand osteoarthritis are limited. Therefore, the Disease Characteristics in Hand OA (DICHOA) initiative was founded in early 2005 with the aim of...

journal_title：Annals of the rheumatic diseases

authors： Kloppenburg M,Stamm T,Watt I,Kainberger F,Cawston TE,Birrell FN,Petersson IF,Saxne T,Kvien TK,Slatkowsky-Christensen B,Dougados M,Gossec L,Breedveld FC,Smolen JS

更新日期：2007-09-01 00:00:00

abstract：:Adenosine deaminase activity was determined in paired samples of serum and synovial fluid taken from patients with rheumatoid arthritis (n = 12), reactive arthritis (n = 13), and osteoarthritis (n = 7), and the value of this investigation in the diagnosis of synovial swellings was assessed. Increased activity was foun...

journal_title：Annals of the rheumatic diseases

authors： Yuksel H,Akoğlu TF

更新日期：1988-06-01 00:00:00

abstract：:The anti-inflammatory effect of single doses and combinations of aspirin and commonly used nonsteroidal anti-inflammatory drugs was investigated by the polyurethane sponge implantation model of acute inflammation. Dose response curves were performed to delineate a suppressive (high) and nonsuppressive (low) dose of ea...

journal_title：Annals of the rheumatic diseases

authors： Garrett R,Manthey B,Vernon-Roberts B,Brooks PM

更新日期：1983-08-01 00:00:00

abstract：BACKGROUND:An imbalance in cytokine homoeostasis is thought to have a key role in the neuropsychiatric syndromes of systemic lupus erythematosus (NPSLE), and recently, a role for chemokines has been noted. OBJECTIVE:To compare concentrations of monocyte chemotactic protein-1 (MCP-1)/CCL2 in cerebral spinal fluid (CSF)...

journal_title：Annals of the rheumatic diseases

authors： Iikuni N,Okamoto H,Yoshio T,Sato E,Kamitsuji S,Iwamoto T,Momohara S,Taniguchi A,Yamanaka H,Minota S,Kamatani N

更新日期：2006-02-01 00:00:00

abstract：OBJECTIVES:To study long term utility of early, continual, and serial use of disease modifying antirheumatic drugs (DMARDs) in early rheumatoid arthritis (RA) in clinical setting. METHODS:A total of 135 patients with early RA were treated according to the "sawtooth" strategy and prospectively followed up to 15 years. ...

journal_title：Annals of the rheumatic diseases

authors： Sokka T,Hannonen P

更新日期：1999-10-01 00:00:00

abstract：:Ten patients (8 female, 2 male) with systemic lupus erythematosus (SLE) were entered into an open trial with the anabolic steroid 19-nortestosterone (19-nor). Their clinical condition did not improve, nor were significant changes observed in the majority of laboratory data. However, overall the platelet count rose, an...

journal_title：Annals of the rheumatic diseases

authors： Hazelton RA,McCruden AB,Sturrock RD,Stimson WH

更新日期：1983-04-01 00:00:00

abstract：OBJECTIVE:Technetium-99m ethyl cysteinate dimer (99mTc ECD) single photon emission computed tomography (SPECT) of the brain was used to detect abnormal regional cerebral blood flow (rCBF) in patients with primary Sjögren's syndrome (pSS) and normal findings on brain magnetic resonance imaging (MRI). METHODS:(99m)Tc EC...

journal_title：Annals of the rheumatic diseases

authors： Chang CP,Shiau YC,Wang JJ,Ho ST,Kao A

更新日期：2002-09-01 00:00:00

abstract：OBJECTIVES:Factors contributing to the development of systemic lupus erythematosus (SLE) remain largely unknown although are likely to include both environmental and genetic components. Studies on murine lupus have indicated a role for an antibody that blocks binding of cytotoxic T lymphocyte associated-4 (CTLA-4) to B...

journal_title：Annals of the rheumatic diseases

authors： Heward J,Gordon C,Allahabadia A,Barnett AH,Franklyn JA,Gough SC

更新日期：1999-03-01 00:00:00

abstract：:Plasma DNA has been measured by a new physiochemical approach based on fluorimetric analysis of phenol extracted nucleic acids electrophoresed on polyacrylamide gels. This method is specific for native double-stranded DNA of molecular weight greater than 5 x 10(6). The use of plasma rigorously freed of leucocytes is e...

journal_title：Annals of the rheumatic diseases

authors： Klemp P,Meyers OL,Harley EH

更新日期：1981-12-01 00:00:00

abstract：OBJECTIVES:To evaluate the risk of septic arthritis (SA) in patients with rheumatoid arthritis (RA) treated with anti-tumour necrosis factor (TNF) therapy. METHODS:Using data from the British Society for Rheumatology Biologics Register, a prospective observational study, the authors compared the risk of SA between 11 ...

journal_title：Annals of the rheumatic diseases

authors： Galloway JB,Hyrich KL,Mercer LK,Dixon WG,Ustianowski AP,Helbert M,Watson KD,Lunt M,Symmons DP,BSR Biologics Register.

更新日期：2011-10-01 00:00:00

abstract：:The case is reported of a 27 year old woman who had mixed connective tissue disease (MCTD) associated with chronic active hepatitis and thyroiditis. Although hepatomegaly is sometimes observed in MCTD, only four cases of MCTD and chronic active hepatitis have been described. It is thought that this is the first report...

journal_title：Annals of the rheumatic diseases

authors： Tomsic M,Ferlan-Marolt V,Kveder T,Hojker S,Rozman B

更新日期：1992-04-01 00:00:00