Serum and synovial fluid adenosine deaminase activity in patients with rheumatoid arthritis, osteoarthritis, and reactive arthritis.

abstract：:Septic arthritis is associated with a definite morbidity which may be related to a delay in diagnosis and hence treatment. The cases of three patients with rheumatoid arthritis and chronic chest disease where the joint sepsis was not the predominant feature are presented. The responsible organism was Streptococcus pne...

journal_title：Annals of the rheumatic diseases

authors： Morley PK,Hull RG,Hall MA

更新日期：1987-06-01 00:00:00

abstract：OBJECTIVES:With the tools available currently, confirming the diagnosis of inclusion body myositis (IBM) can be difficult. Many patients are initially misdiagnosed with polymyositis (PM). In this observational study at a UK adult neuromuscular centre, we investigated whether amyloid positron emission tomography could d...

journal_title：Annals of the rheumatic diseases

authors： Lilleker JB,Hodgson R,Roberts M,Herholz K,Howard J,Hinz R,Chinoy H

更新日期：2019-05-01 00:00:00

abstract：:The relation of habitual knuckle cracking to osteoarthrosis with functional impairment of the hand has long been considered an old wives' tale without experimental support. The mechanical sequelae of knuckle cracking have been shown to produce the rapid release of energy in the form of sudden vibratory energy, much li...

journal_title：Annals of the rheumatic diseases

authors： Castellanos J,Axelrod D

更新日期：1990-05-01 00:00:00

abstract：BACKGROUND:Psoriatic arthritis (PsA) is a chronic inflammatory disease, characterised by synovitis and destruction of articular cartilage/bone. Janus-kinase and signal transducer and activator of transcription (JAK-STAT) signalling pathway is implicated in the pathogenesis of PsA. OBJECTIVES:To examine the effect of t...

journal_title：Annals of the rheumatic diseases

authors： Gao W,McGarry T,Orr C,McCormick J,Veale DJ,Fearon U

更新日期：2016-01-01 00:00:00

abstract：OBJECTIVE:To investigate the possibility of drug-free remission in patients with psoriatic arthritis (PsA) in continuous remission. METHODS:Prospective observational study in disease-modifying antirheumatic drug (DMARD)-treated PsA patients in continuous disease remission (no musculoskeletal symptoms, no or minimal sk...

journal_title：Annals of the rheumatic diseases

authors： Araujo EG,Finzel S,Englbrecht M,Schreiber DA,Faustini F,Hueber A,Nas K,Rech J,Schett G

更新日期：2015-04-01 00:00:00

abstract：BACKGROUND:Systemic sclerosis (SSc) is an autoimmune disease characterised by fibrosis of the skin and the internal organs. Except for anticentromere, antitopoisomerase I and antipolymerase III antibodies, there are no reliable circulating markers predicting susceptibility and internal organ complications. This study h...

journal_title：Annals of the rheumatic diseases

authors： van Bon L,Cossu M,Loof A,Gohar F,Wittkowski H,Vonk M,Roth J,van den Berg W,van Heerde W,Broen JC,Radstake TR

更新日期：2014-08-01 00:00:00

abstract：OBJECTIVES:The aim of this study was to evaluate serum interleukin (IL) 12 concentration in patients with juvenile chronic arthritis (JCA), according to disease subtype, activity, and duration. IL12 has been demonstrated to prime the selective expansion of T helper (Th) cells with a Th1-type pattern of cytokine product...

journal_title：Annals of the rheumatic diseases

authors： Gattorno M,Picco P,Vignola S,Stalla F,Buoncompagni A,Pistoia V

更新日期：1998-07-01 00:00:00

abstract：BACKGROUND:Mast cells have been implicated in the pathogenesis of arthritis, but elucidation of their precise role has been hampered by a lack of efficient and selective inhibitors of their function. OBJECTIVE:To elucidate the role of mast cells in the pathogenesis of rheumatoid arthritis (RA) and to assess whether ap...

journal_title：Annals of the rheumatic diseases

authors： Juurikivi A,Sandler C,Lindstedt KA,Kovanen PT,Juutilainen T,Leskinen MJ,Mäki T,Eklund KK

更新日期：2005-08-01 00:00:00

abstract：OBJECTIVE:To elucidate the differential role of peptidyl arginine deiminase 4 (PADI4) polymorphism in rheumatoid arthritis (RA) between Asian and European populations, possible gene-environmental interactions among the PADI4 polymorphism, sex and smoking status were analysed. METHODS:Three independent sets of case-con...

journal_title：Annals of the rheumatic diseases

authors： Kochi Y,Thabet MM,Suzuki A,Okada Y,Daha NA,Toes RE,Huizinga TW,Myouzen K,Kubo M,Yamada R,Nakamura Y,Yamamoto K

更新日期：2011-03-01 00:00:00

abstract：OBJECTIVE:To clarify the deleterious effects of Mayer's haematoxylin staining procedure which result in a decrease in, or complete loss of, the number of calcium pyrophosphate dihydrate (CPPD) crystals, and to determine the proper staining period for preserving the crystals in a histological paraffin section of articul...

journal_title：Annals of the rheumatic diseases

authors： Ohira T,Ishikawa K

更新日期：2001-01-01 00:00:00

abstract：OBJECTIVES:To assess the prevalence and patterns of cardiac abnormalities as detected by cardiac magnetic resonance imaging (MRI) in systemic sclerosis (SSc). METHODS:Fifty-two consecutive patients with SSc underwent cardiac MRI to determine morphological, functional, perfusion at rest and delayed enhancement abnormal...

journal_title：Annals of the rheumatic diseases

authors： Hachulla AL,Launay D,Gaxotte V,de Groote P,Lamblin N,Devos P,Hatron PY,Beregi JP,Hachulla E

更新日期：2009-12-01 00:00:00

abstract：OBJECTIVE:To define the mechanisms whereby methotrexate (MTX) manifests its effects in patients with rheumatoid arthritis. METHODS:T and B cells from peripheral blood and rheumatoid synovial tissues, synovial adherent cells, and the human fibrosarcoma cell line HT1080 and its mutant (defective in an enzyme in the nucl...

journal_title：Annals of the rheumatic diseases

authors： Nakajima A,Hakoda M,Yamanaka H,Kamatani N,Kashiwazaki S

更新日期：1996-04-01 00:00:00

abstract：BACKGROUND:A recent study from our laboratory showed that induction of the multidrug resistance related drug efflux pump ABCG2 contributed to acquired resistance of human T cells to the disease modifying antirheumatic drug (DMARD) sulfasalazine (SSZ). OBJECTIVES:To investigate the duration of SSZ resistance and ABCG2 ...

journal_title：Annals of the rheumatic diseases

authors： van der Heijden J,de Jong MC,Dijkmans BA,Lems WF,Oerlemans R,Kathmann I,Scheffer GL,Scheper RJ,Assaraf YG,Jansen G

更新日期：2004-02-01 00:00:00

abstract：OBJECTIVES:Recent animal studies have revealed critical roles of interleukin (IL)17, which is produced by a newly identified subset of helper T cells, Th17 cells, in the development of autoimmune diseases including arthritis. However, in human rheumatoid arthritis (RA), detailed characteristics and the prevalence of Th...

journal_title：Annals of the rheumatic diseases

authors： Yamada H,Nakashima Y,Okazaki K,Mawatari T,Fukushi JI,Kaibara N,Hori A,Iwamoto Y,Yoshikai Y

更新日期：2008-09-01 00:00:00

abstract：OBJECTIVES:To investigate the association of lifestyle factors with risk of inflammatory polyarthritis (IP) and rheumatoid arthritis (RA). METHODS:The European Prospective Investigation of Cancer, Norfolk, UK (EPIC-Norfolk) gathered lifestyle data from participants aged 40-79 years from 1993 to 1997. Individuals who s...

journal_title：Annals of the rheumatic diseases

authors： Lahiri M,Luben RN,Morgan C,Bunn DK,Marshall T,Lunt M,Verstappen SM,Symmons DP,Khaw KT,Wareham N,Bruce IN

更新日期：2014-01-01 00:00:00

abstract：OBJECTIVES:This integrated analysis presents the safety profile of upadacitinib, a Janus kinase inhibitor, at 15 mg and 30 mg once daily in patients with moderately to severely active rheumatoid arthritis (RA). METHODS:Treatment-emergent adverse events (TEAEs) and laboratory data from five randomised, placebo- or acti...

journal_title：Annals of the rheumatic diseases

authors： Cohen SB,van Vollenhoven RF,Winthrop KL,Zerbini CAF,Tanaka Y,Bessette L,Zhang Y,Khan N,Hendrickson B,Enejosa JV,Burmester GR

更新日期：2020-10-28 00:00:00

abstract：:The prostaglandin E (PGE) level in the knee joint fluid was determined by radioimmunoassay before and after anti-inflammatory therapy with flurbiprofen in 8 patients with rheumatoid arthritis (RA) and 4 patients with osteoarthritis (OA). The level of PGE in RA joint fluids before the anti-inflammatory treatment was 9....

journal_title：Annals of the rheumatic diseases

authors： Tokunaga M,Ohuchi K,Yoshizawa S,Tsurufuji S,Rikimaru A,Wakamatsu E

更新日期：1981-10-01 00:00:00

abstract：OBJECTIVES:The aim of this report is to demonstrate pharmacokinetic (PK) and pharmacodynamic (PD) equivalence as well as similar efficacy, safety and immunogenicity between GP2013, a biosimilar rituximab, and innovator rituximab (RTX) in patients with rheumatoid arthritis (RA) with inadequate response or intolerance to...

journal_title：Annals of the rheumatic diseases

authors： Smolen JS,Cohen SB,Tony HP,Scheinberg M,Kivitz A,Balanescu A,Gomez-Reino J,Cen L,Zhu P,Shisha T

更新日期：2017-09-01 00:00:00

abstract：OBJECTIVES:Rheumatoid factor (RF) and anti-cyclic citrullinated protein/peptide antibodies (ACPA) are integrated in the 2010 American College of Rheumatology/European League Against Rheumatism (ACR/EULAR) classification criteria for rheumatoid arthritis (RA). The objectives of this study were to evaluate the technical ...

journal_title：Annals of the rheumatic diseases

authors： Van Hoovels L,Jacobs J,Vander Cruyssen B,Van den Bremt S,Verschueren P,Bossuyt X

更新日期：2018-05-01 00:00:00

abstract：:The response of synovial lymphocytes from a 65-year-old lady with persistent polyarthritis, to rubella antigen and a number of other microbial agents was studied over a period of 11 months by [3H]thymidine incorporation. The results were correlated with the ability to isolate rubella virus from both peripheral blood a...

journal_title：Annals of the rheumatic diseases

authors： Chantler JK,da Roza DM,Bonnie ME,Reid GD,Ford DK

更新日期：1985-08-01 00:00:00

abstract：OBJECTIVE:To investigate quantitatively the mRNA expression levels of YKL-40, an established marker of rheumatoid and osteoarthritic cartilage degeneration in synovial fluid and serum, and a closely related molecule YKL-39, in articular chondrocytes. METHODS:cDNA array and online quantitative polymerase chain reaction...

journal_title：Annals of the rheumatic diseases

authors： Knorr T,Obermayr F,Bartnik E,Zien A,Aigner T

更新日期：2003-10-01 00:00:00

abstract：OBJECTIVES:To determine the diagnostic value of beta 2 microglobulin in parotid saliva, its concentration in relation to salivary flow was determined in 29 patients with primary Sjögren's syndrome and in 30 normal controls. The specific secretion rate of beta 2 microglobulin was calculated. METHODS:Parotid saliva samp...

journal_title：Annals of the rheumatic diseases

authors： van der Geest SA,Markusse HM,Swaak AJ

更新日期：1993-06-01 00:00:00

abstract：:The case is described of a patient with scleromyxoedema with features typical of systemic sclerosis. The features were so characteristic that the disease was misdiagnosed as systemic sclerosis. A brief review of the association of the two diseases is given. ...

journal_title：Annals of the rheumatic diseases

authors： Verma UN,Singh RR,Misra R,Naik S,Agarwal SS

更新日期：1992-10-01 00:00:00

abstract：OBJECTIVES:To elucidate the contribution of HLA-DR-DQ haplotypes and their genotypic combinations to susceptibility to rheumatoid arthritis, and to evaluate the various models for HLA associated risk for the disease in a series of Finnish patients. METHODS:322 Finnish patients with rheumatoid arthritis were typed for ...

journal_title：Annals of the rheumatic diseases

authors： Laivoranta-Nyman S,Möttönen T,Hermann R,Tuokko J,Luukkainen R,Hakala M,Hannonen P,Korpela M,Yli-Kerttula U,Toivanen A,Ilonen J,FIN-RACo Trial Group.

更新日期：2004-11-01 00:00:00

abstract：OBJECTIVES:To assess the reliability of the OMERACT ultrasound (US) definitions for the identification of calcium pyrophosphate deposition disease (CPPD) at the metacarpal-phalangeal, triangular fibrocartilage of the wrist (TFC), acromioclavicular (AC) and hip joints. METHODS:A web-based exercise and subsequent patien...

journal_title：Annals of the rheumatic diseases

authors： Filippou G,Scirè CA,Adinolfi A,Damjanov NS,Carrara G,Bruyn GAW,Cazenave T,D'Agostino MA,Delle Sedie A,Di Sabatino V,Diaz Cortes ME,Filippucci E,Gandjbakhch F,Gutierrez M,Maccarter DK,Micu M,Möller Parera I,Mouterde G,

更新日期：2018-08-01 00:00:00

abstract：:Two animal models were used to investigate the mode of action of levamisole and thymopoietin. Neither compound influenced the subcutaneous carrageenan air pouch. While thymopoietin inhibited the formation of cotton pellet granulomas, levamisole enhanced it. This supports the conclusions of clinical studies reported el...

journal_title：Annals of the rheumatic diseases

authors： Thrower PA,Sedgwick AD,Smith ER,Willoughby DA,Huskisson EC

更新日期：1983-02-01 00:00:00

abstract：BACKGROUND:Prevalence estimates of rheumatoid arthritis (RA) vary across Europe. Recent estimates in southern European countries showed a lower prevalence than in northern countries. OBJECTIVES:To estimate the prevalence of RA in France in a multiregional representative sample in the year 2001. METHODS:A two stage ra...

journal_title：Annals of the rheumatic diseases

authors： Guillemin F,Saraux A,Guggenbuhl P,Roux CH,Fardellone P,Le Bihan E,Cantagrel A,Chary-Valckenaere I,Euller-Ziegler L,Flipo RM,Juvin R,Behier JM,Fautrel B,Masson C,Coste J

更新日期：2005-10-01 00:00:00

abstract：:Antibiotic treatment of all disease manifestations after infection with Borrelia sensu lato spp aims at resolving the presenting disease manifestation and preventing late stage disease. The goals are resolution of the preventing manifestation and prevention of the spread of bacteria to prevent late disease like arthri...

journal_title：Annals of the rheumatic diseases

authors： Dinser R,Jendro MC,Schnarr S,Zeidler H

更新日期：2005-04-01 00:00:00

abstract：OBJECTIVE:To elaborate a clinical practice decision tree for the choice of the first disease modifying antirheumatic drug (DMARD) for untreated rheumatoid arthritis of less than six months' duration. METHODS:Four steps were employed: (1) review of published reports on DMARD efficacy against rheumatoid arthritis; (2) i...

journal_title：Annals of the rheumatic diseases

authors： Le Loët X,Berthelot JM,Cantagrel A,Combe B,De Bandt M,Fautrel B,Flipo RM,Lioté F,Maillefert JF,Meyer O,Saraux A,Wendling D,Guillemin F

更新日期：2006-01-01 00:00:00

abstract：BACKGROUND:The study aimed to evaluate the use of positron emission tomography/computed tomography (PET/CT) with (68)Ga-PRGD2 as the tracer for imaging of synovial angiogenesis in patients with rheumatoid arthritis (RA). METHODS:Twenty untreated active patients with RA underwent (68)Ga-PRGD2 PET/CT and (18)F-FDG PET/C...

journal_title：Annals of the rheumatic diseases

authors： Zhu Z,Yin Y,Zheng K,Li F,Chen X,Zhang F,Zhang X

更新日期：2014-06-01 00:00:00