Preservation of calcium pyrophosphate dihydrate crystals: effect of Mayer's haematoxylin staining period.

abstract：OBJECTIVE:To investigate polymorphisms of both codon 54 allele and promoter variants of the mannose binding lectin (MBL) gene in patients with primary Sjögren's syndrome (SS). METHODS:Polymorphisms of codon 54 allele and promoter variants of the MBL gene in 104 patients with SS and 143 healthy controls were determined...

journal_title：Annals of the rheumatic diseases

authors： Wang ZY,Morinobu A,Kanagawa S,Kumagai S

更新日期：2001-05-01 00:00:00

abstract：OBJECTIVES:To analyse the similarities and discrepancies between the official rheumatology specialty training programmes across Europe. METHODS:A steering committee defined the main aspects of training to be assessed. In 2013, the rheumatology official training programmes were reviewed for each of the European League ...

journal_title：Annals of the rheumatic diseases

authors： Sivera F,Ramiro S,Cikes N,Dougados M,Gossec L,Kvien TK,Lundberg IE,Mandl P,Moorthy A,Panchal S,da Silva JA,Bijlsma JW,Working Group on Training in Rheumatology across Europe.

更新日期：2015-06-01 00:00:00

abstract：:Spontaneous production of the interferon induced enzyme 2',5'-oligoadenylate synthetase (2',5'-A synthetase) was significantly greater in blood lymphocytes of patients with systemic lupus erythematosus (SLE), Behçet's syndrome, and rheumatoid arthritis than in control lymphocytes. Alpha interferon (IFN-alpha) induced ...

journal_title：Annals of the rheumatic diseases

authors： Hylton W,Cayley J,Dore C,Denman AM

更新日期：1986-03-01 00:00:00

abstract：OBJECTIVE:To determine the relative contribution of work-related mechanical (injury) factors and psychosocial factors to the onset of a new episode of knee pain, in a cohort of newly employed workers. METHODS:A prospective cohort study of newly employed workers from 12 diverse occupational settings in England (The New...

journal_title：Annals of the rheumatic diseases

authors： Jones GT,Harkness EF,Nahit ES,McBeth J,Silman AJ,Macfarlane GJ

更新日期：2007-03-01 00:00:00

abstract：OBJECTIVE:Anticitrullinated protein antibodies (ACPA) are the most predictive factor for the development of rheumatoid arthritis (RA). Epitope spreading towards more citrullinated epitopes occurs before the onset of RA. Here, the authors investigated whether specific epitope recognition allows the identification of spe...

journal_title：Annals of the rheumatic diseases

authors： Willemze A,Böhringer S,Knevel R,Levarht EW,Stoeken-Rijsbergen G,Houwing-Duistermaat JJ,van der Helm-van Mil AH,Huizinga TW,Toes RE,Trouw LA

更新日期：2012-02-01 00:00:00

abstract：BACKGROUND:The heteropolymer technology was developed to remove pathogens from the circulation. OBJECTIVES:To evaluate the safety and tolerability of a single administration and to establish proof of principle for ETI-104 in normal healthy volunteers (NHV) and patients with systemic lupus erythematosus (SLE) METHODS: ...

journal_title：Annals of the rheumatic diseases

authors： Iking-Konert C,Stocks S,Weinsberg F,Engelbrecht R,Bleck E,Perniok A,Fischer-Betz R,Pincus S,Nardone L,Schneider M

更新日期：2004-09-01 00:00:00

abstract：OBJECTIVE:To assess survival and identify predictors of survival in patients with systemic sclerosis-interstitial lung disease (SSc-ILD) who participated in the Scleroderma Lung Studies (SLS) I and II. METHODS:SLS I randomised 158 patients with SSc-ILD to 1  year of oral cyclophosphamide (CYC) vs placebo. SLS II rando...

journal_title：Annals of the rheumatic diseases

authors： Volkmann ER,Tashkin DP,Sim M,Li N,Goldmuntz E,Keyes-Elstein L,Pinckney A,Furst DE,Clements PJ,Khanna D,Steen V,Schraufnagel DE,Arami S,Hsu V,Roth MD,Elashoff RM,Sullivan KM,SLS I and SLS II study groups.

更新日期：2019-01-01 00:00:00

abstract：OBJECTIVE:The effect of adalimumab on hand osteoporosis was examined and related to radiographic joint damage in the three treatment arms of the PREMIER study: adalimumab plus methotrexate, adalimumab and methotrexate monotherapy. Predictors of hand bone loss were also searched for. METHODS:768 patients (537 fulfilled...

journal_title：Annals of the rheumatic diseases

authors： Hoff M,Kvien TK,Kälvesten J,Elden A,Haugeberg G

更新日期：2009-07-01 00:00:00

abstract：:Serum samples were obtained from patients with polymyalgia rheumatica (PMR: n = 10) or giant cell arteritis (GCA; n = 7), or both. Samples were taken either before treatment or within one week of starting prednisolone. Immune complexes (IC) were concentrated by polyethylene glycol (PEG) precipitation then purified wit...

journal_title：Annals of the rheumatic diseases

authors： Smith AJ,Kyle V,Cawston TE,Hazleman BL

更新日期：1987-06-01 00:00:00

abstract：:Gout and classical rheumatoid arthritis rarely coexist. We report a patient with strong evidence for both these diseases. Possible reasons for the negative correlation between these diseases are summarised. One hypothesis suggests inhibition of surface activity of monosodium urate crystals (MSU) by binding of rheumato...

journal_title：Annals of the rheumatic diseases

authors： Gordon TP,Ahern MJ,Reid C,Roberts-Thomson PJ

更新日期：1985-06-01 00:00:00

abstract：OBJECTIVES:To present and analyse the literature sources regarding the management of Behçet disease (BD) identified during the systematic literature research, which formed the basis for the European League Against Rheumatism (EULAR) evidence-based recommendations for the management of BD. METHODS:Problem areas and rel...

journal_title：Annals of the rheumatic diseases

authors： Hatemi G,Silman A,Bang D,Bodaghi B,Chamberlain AM,Gul A,Houman MH,Kötter I,Olivieri I,Salvarani C,Sfikakis PP,Siva A,Stanford MR,Stübiger N,Yurdakul S,Yazici H

更新日期：2009-10-01 00:00:00

abstract：OBJECTIVES:Interleukin (IL) 34 is a new cytokine implicated in macrophage differentiation and osteoclastogenesis. This study assessed IL-34 expression in the tissue of patients with rheumatoid arthritis (RA). METHODS:Immunohistochemistry was performed in synovial biopsies from patients with RA (n=20), osteoarthritis (...

journal_title：Annals of the rheumatic diseases

authors： Chemel M,Le Goff B,Brion R,Cozic C,Berreur M,Amiaud J,Bougras G,Touchais S,Blanchard F,Heymann MF,Berthelot JM,Verrecchia F,Heymann D

更新日期：2012-01-01 00:00:00

abstract：:The question 'Does the use of second-line therapy confer long-term benefit on outcome measures in rheumatoid arthritis?' remains unanswered. The major obstacle which prevents collection of the necessary data is the lack of a suitable control group. In this report experience with three 'second-line placebo groups' is d...

journal_title：Annals of the rheumatic diseases

authors： Pullar T,Capell HA

更新日期：1985-02-01 00:00:00

abstract：BACKGROUND:The study aimed to evaluate the use of positron emission tomography/computed tomography (PET/CT) with (68)Ga-PRGD2 as the tracer for imaging of synovial angiogenesis in patients with rheumatoid arthritis (RA). METHODS:Twenty untreated active patients with RA underwent (68)Ga-PRGD2 PET/CT and (18)F-FDG PET/C...

journal_title：Annals of the rheumatic diseases

authors： Zhu Z,Yin Y,Zheng K,Li F,Chen X,Zhang F,Zhang X

更新日期：2014-06-01 00:00:00

abstract：BACKGROUND:Aiming at therapeutic targets has reduced the risk of organ failure in many diseases such as diabetes or hypertension. Such targets have not been defined for rheumatoid arthritis (RA). OBJECTIVE:/st> To develop recommendations for achieving optimal therapeutic outcomes in RA. METHODS:A task force of rheuma...

journal_title：Annals of the rheumatic diseases

authors： Smolen JS,Aletaha D,Bijlsma JW,Breedveld FC,Boumpas D,Burmester G,Combe B,Cutolo M,de Wit M,Dougados M,Emery P,Gibofsky A,Gomez-Reino JJ,Haraoui B,Kalden J,Keystone EC,Kvien TK,McInnes I,Martin-Mola E,Montecucco C,

更新日期：2010-04-01 00:00:00

abstract：OBJECTIVE:To determine the circulating serum concentrations of nerve growth factor (NGF) and compare them with indices of disease activity in juvenile chronic arthritis. METHODS:NGF concentrations were evaluated with a two site immunoenzymatic assay (ELISA), in 17 children with systemic, 39 with polyarticular, and 24 ...

journal_title：Annals of the rheumatic diseases

authors： Falcini F,Matucci Cerinic M,Lombardi A,Generini S,Pignone A,Tirassa P,Ermini M,Lepore L,Partsch G,Aloe L

更新日期：1996-10-01 00:00:00

abstract：:The 13 questions to which 173 rheumatic outpatients most frequently wished to know the answer were made the basis of a structured interview. Two lengths of interview were conducted in a controlled trial (short being of 2 minutes' duration, long ranging from 4 to 11 minutes). Sixty patients referred directly from their...

journal_title：Annals of the rheumatic diseases

authors： Wright V,Hopkins R,Burton K

更新日期：1982-06-01 00:00:00

abstract：BACKGROUND:Several studies suggest a role of the growth hormone (GH)/insulin-like growth factor-1 (IGF-1) axis in the pathophysiology of primary osteoarthritis (OA). A common polymorphism of the GH receptor (exon 3 deletion, d3-GHR) is associated with increased GH/IGF-1 activity. OBJECTIVE:To study associations betwee...

journal_title：Annals of the rheumatic diseases

authors： Claessen KM,Kloppenburg M,Kroon HM,Bijsterbosch J,Pereira AM,Romijn JA,van der Straaten T,Nelissen RG,Hofman A,Uitterlinden AG,Duijnisveld BJ,Lakenberg N,Beekman M,van Meurs JB,Slagboom PE,Biermasz NR,Meulenbelt I

更新日期：2014-02-01 00:00:00

abstract：:A three phase study was designed to define further the sensitivity and specificity of symptomatic salicylate ototoxicity (primarily tinnitus) for serum salicylate concentrations. In phase one 260 patients with osteoarthritis and 112 with rheumatoid arthritis, none taking salicylates, were interviewed about their ear s...

journal_title：Annals of the rheumatic diseases

authors： Halla JT,Atchison SL,Hardin JG

更新日期：1991-10-01 00:00:00

abstract：:A novel explanation for the natural history of joint destruction in the early phase of ankylosing spondylitis is proposed on the basis of the clinical history, x-ray appearance, operative findings, and histopathology of a young patient believed to be suffering from the peripheral form of this disease. ...

journal_title：Annals of the rheumatic diseases

authors： Pasion EG,Goodfellow JW

更新日期：1975-02-01 00:00:00

abstract：OBJECTIVES:Different prevalences of generalised osteoarthritis (GOA) in patients with knee and hip OA have been reported. The aim of this investigation was to evaluate radiographic and clinical patterns of disease in a hospital based population of patient subgroups with advanced hip and knee OA and to compare the preva...

journal_title：Annals of the rheumatic diseases

authors： Günther KP,Stürmer T,Sauerland S,Zeissig I,Sun Y,Kessler S,Scharf HP,Brenner H,Puhl W

更新日期：1998-12-01 00:00:00

abstract：:We have identified regular thermal patterns over normal knee, ankle, and elbow joints and demonstrate how synovitis affecting these joints may be identified by alteration or loss of the thermal pattern. Sixty healthy volunteers were thermographed on a total of 190 occasions, and 614 out of 618 joints conformed to the ...

journal_title：Annals of the rheumatic diseases

authors： Salisbury RS,Parr G,De Silva M,Hazleman BL,Page-Thomas DP

更新日期：1983-10-01 00:00:00

abstract：:A nutritional assessment of 50 patients with rheumatoid arthritis (RA) showed evidence of malnutrition in 13 (26%), while all 50 control subjects had normal nutritional status. Of the anthropometric measurements the body-mass index and triceps skinfold thickness values in men and women were significantly reduced in RA...

journal_title：Annals of the rheumatic diseases

authors： Helliwell M,Coombes EJ,Moody BJ,Batstone GF,Robertson JC

更新日期：1984-06-01 00:00:00

abstract：:Expression of major histocompatibility complex (MHC) class II and other lymphocyte activation markers on peripheral blood and synovial fluid T lymphocytes from patients with rheumatoid arthritis (RA), psoriatic arthritis, and Reiter's syndrome were measured and the mean fluorescence intensities of these antigens were ...

journal_title：Annals of the rheumatic diseases

authors： Smith MD,Roberts-Thomson PJ

更新日期：1990-02-01 00:00:00

abstract：:The pattern of joint involvement on conventional radiographs and the four hour gammacamera image of 99Tc HMDP bone scans were studied in 33 patients with generalised nodal osteoarthritis. Both techniques showed the predominant involvement of the distal interphalangeal, scaphotrapezial, and first carpometacarpal joints...

journal_title：Annals of the rheumatic diseases

authors： Hutton CW,Higgs ER,Jackson PC,Watt I,Dieppe PA

更新日期：1986-08-01 00:00:00

abstract：:Today, patients' functioning is a central issue in medicine. Concepts, classifications, and measurements of functioning and health, such as the International Classification of Functioning, Disability and Health (ICF) are of prime importance in clinical practice, teaching, and research. This report compares the content...

journal_title：Annals of the rheumatic diseases

authors： Stucki G,Cieza A

更新日期：2004-11-01 00:00:00

abstract：BACKGROUND:Psoriatic arthritis (PsA) is a chronic inflammatory disease, characterised by synovitis and destruction of articular cartilage/bone. Janus-kinase and signal transducer and activator of transcription (JAK-STAT) signalling pathway is implicated in the pathogenesis of PsA. OBJECTIVES:To examine the effect of t...

journal_title：Annals of the rheumatic diseases

authors： Gao W,McGarry T,Orr C,McCormick J,Veale DJ,Fearon U

更新日期：2016-01-01 00:00:00

abstract：:In the use of anti-inflammatory compounds, sustained serum levels are thought to be related to drug efficacy. This study shows that frequent clinical administration of indomethacin can result in sustained serum levels of the drug and that food and antacid may have important modifying effects on serum indomethacin conc...

journal_title：Annals of the rheumatic diseases

authors： Emori HW,Paulus H,Bluestone R,Champion GD,Pearson C

更新日期：1976-08-01 00:00:00

abstract：:In order to evaluate the incidence and aetiology of hypergastrinaemia 53 patients with seropositive rheumatoid arthritis were examined for gastric acid secretion, fasting serum gastrin concentration, circulating parietal cell antibodies, and some parameters of the activity of inflammation of rheumatoid arthritis. The ...

journal_title：Annals of the rheumatic diseases

authors： de Witte TJ,Geerdink PJ,Lamers CB,Boerbooms AM,van der Korst JK

更新日期：1979-02-01 00:00:00

abstract：OBJECTIVES:Hospitalisation is a risk factor for flares in people with gout. However, the predictors of inpatient gout flare are not well understood. The aim of this study was to develop a prediction model for inpatient gout flare among people with comorbid gout. METHODS:We used data from a retrospective cohort of hosp...

journal_title：Annals of the rheumatic diseases

authors： Jatuworapruk K,Grainger R,Dalbeth N,Taylor WJ

更新日期：2020-03-01 00:00:00