Heat distribution over normal and abnormal joints: thermal pattern and quantification.

abstract：OBJECTIVES:While new treatments for rheumatoid arthritis (RA) have markedly improved disease control by targeting immune/inflammatory pathways, current treatments rarely induce remission, underscoring the need for therapies that target other aspects of the disease. Little is known about the regulation of disease severi...

journal_title：Annals of the rheumatic diseases

authors： Laragione T,Brenner M,Lahiri A,Gao E,Harris C,Gulko PS

更新日期：2018-11-01 00:00:00

abstract：BACKGROUND:Although there has been major progress in gout imaging, no gout classification criteria currently include advanced imaging techniques. OBJECTIVE:To examine the usefulness of imaging modalities in the classification of gout when compared to monosodium urate (MSU) crystal confirmation as the gold standard, in...

journal_title：Annals of the rheumatic diseases

authors： Ogdie A,Taylor WJ,Weatherall M,Fransen J,Jansen TL,Neogi T,Schumacher HR,Dalbeth N

更新日期：2015-10-01 00:00:00

abstract：OBJECTIVE:To assess how socioeconomic deprivation influences the presentation, treatment, and outcome of patients with rheumatoid arthritis (RA). METHODS:Three year follow up of 869 consecutive patients with RA from nine hospital rheumatology clinics, with patients categorised by the Carstairs deprivation score of the...

journal_title：Annals of the rheumatic diseases

authors：

更新日期：2000-10-01 00:00:00

abstract：BACKGROUND:Primary Sjögren's syndrome (pSS) is a systemic autoimmune disease characterised by aberrant B cell hyperactivation, whose mechanism is partially understood. METHODS:We performed whole transcriptome sequencing of B cells from three pSS patients and three matched healthy controls (HC). Differentially expressi...

journal_title：Annals of the rheumatic diseases

authors： Sun JL,Zhang HZ,Liu SY,Lian CF,Chen ZL,Shao TH,Zhang S,Zhao LL,He CM,Wang M,Zhang W,Chen H,Zhang FC

更新日期：2020-04-01 00:00:00

abstract：BACKGROUND:We report on a workshop on ethical and legal constraints on data sharing between countries in multinational epidemiologic research in Europe that was held in January 2007 in Potsdam, Germany. The participants were experienced epidemiologic and clinical researchers from eight European countries. The aim of th...

journal_title：Annals of the rheumatic diseases

authors： Zink A,Silman AJ

更新日期：2008-07-01 00:00:00

abstract：:A putative retravirus was isolated from a cell culture derived by fusion of mink and dog cell lines with cultured placental cells from a patient with systemic lupus erythematosus. The virus was detected by reverse transcriptase assay of supernatant medium after prolonged subculturing. Its characterisation, including s...

journal_title：Annals of the rheumatic diseases

authors： Phillips PE,Sellers SA,Cotronei SL

更新日期：1978-06-01 00:00:00

abstract：BACKGROUND:Comprehensive multisystem clinical assessment using the Birmingham Vasculitis Activity score (BVAS) is widely used in therapeutic studies of systemic vasculitis. Extensive use suggested a need to revise the instrument. The previous version of BVAS has been revised, according to usage and reviewed by an exper...

journal_title：Annals of the rheumatic diseases

authors： Mukhtyar C,Lee R,Brown D,Carruthers D,Dasgupta B,Dubey S,Flossmann O,Hall C,Hollywood J,Jayne D,Jones R,Lanyon P,Muir A,Scott D,Young L,Luqmani RA

更新日期：2009-12-01 00:00:00

abstract：OBJECTIVE:To evaluate changes in health-related quality of life (HRQoL) in patients with refractory juvenile idiopathic arthritis (JIA) who are being treated with etanercept. METHODS:53 patients with JIA from seven Dutch centres were included. HRQoL was measured by the Childhood Health Assessment Questionnaire (CHAQ),...

journal_title：Annals of the rheumatic diseases

authors： Prince FH,Geerdink LM,Borsboom GJ,Twilt M,van Rossum MA,Hoppenreijs EP,Cate RT,Koopman-Keemink Y,van Santen-Hoeufft M,Raat H,van Suijlekom-Smit LW

更新日期：2010-01-01 00:00:00

abstract：OBJECTIVE:To investigate the incidence of new cancer diagnoses in a community sample of patients with polymyalgia rheumatica (PMR). METHODS:All incident cases of PMR in the UK General Practice Research Database (GPRD) (1987-99), without pre-existing cancer or vascular disease and treated with corticosteroids (n=2877) ...

journal_title：Annals of the rheumatic diseases

authors： Muller S,Hider SL,Belcher J,Helliwell T,Mallen CD

更新日期：2014-10-01 00:00:00

abstract：OBJECTIVE:To investigate the prediction of the postpartum onset of rheumatoid arthritis (RA). METHODS:Two thousand five hundred and forty seven healthy pregnant subjects were examined prospectively and the relation between serum rheumatoid factors (RF) and postpartum onset of RA was observed. Rheumatoid factors were m...

journal_title：Annals of the rheumatic diseases

authors： Iijima T,Tada H,Hidaka Y,Yagoro A,Mitsuda N,Kanzaki T,Murata Y,Amino N

更新日期：1998-08-01 00:00:00

abstract：:This paper reports the spontaneous development of synovitis in 'Old English' rabbits concurrent with serum IgM rheumatoid factor. Female rabbits developed lesions at a higher incidence than males (42% compared with 17%) and the pathology was of a more severe nature. In the female rabbits synovitis was associated with ...

journal_title：Annals of the rheumatic diseases

authors： Hanglow AC,Welsh CJ,Conn P,Thomas DS,Coombs RR

更新日期：1986-04-01 00:00:00

abstract：BACKGROUND:An imbalance in cytokine homoeostasis is thought to have a key role in the neuropsychiatric syndromes of systemic lupus erythematosus (NPSLE), and recently, a role for chemokines has been noted. OBJECTIVE:To compare concentrations of monocyte chemotactic protein-1 (MCP-1)/CCL2 in cerebral spinal fluid (CSF)...

journal_title：Annals of the rheumatic diseases

authors： Iikuni N,Okamoto H,Yoshio T,Sato E,Kamitsuji S,Iwamoto T,Momohara S,Taniguchi A,Yamanaka H,Minota S,Kamatani N

更新日期：2006-02-01 00:00:00

abstract：OBJECTIVE:To compare responsiveness of the Harris Hip Score with generic measures (that is, the Short Form-36 (SF-36), and a test of walking speed and pain during walking) in patients with osteoarthritis (OA) of the hip. METHOD:The first 75 cases within the population of a randomised clinical trial on manual therapy a...

journal_title：Annals of the rheumatic diseases

authors： Hoeksma HL,Van Den Ende CH,Ronday HK,Heering A,Breedveld FC

更新日期：2003-10-01 00:00:00

abstract：:We report two patients with systemic lupus erythematosus who subsequently developed thrombotic thrombocytopenic purpura. In each case the coexistence of these two conditions was confirmed by pathological findings. Both patients responded to treatment, but one eventually died. A review of the literature suggests a poss...

journal_title：Annals of the rheumatic diseases

authors： Fox DA,Faix JD,Coblyn J,Fraser P,Smith B,Weinblatt ME

更新日期：1986-04-01 00:00:00

abstract：OBJECTIVE:Although genome-wide association studies (GWAS) have identified approximately 100 loci for rheumatoid arthritis (RA), the disease mechanisms are not completely understood. We evaluated the pathogenesis of RA by focusing on rare coding variants. METHODS:The coding regions of 98 candidate genes identified by G...

journal_title：Annals of the rheumatic diseases

authors： Motegi T,Kochi Y,Matsuda K,Kubo M,Yamamoto K,Momozawa Y

更新日期：2019-08-01 00:00:00

abstract：:To transcribe the treat-to-target (T2T) recommendations into a version that can be easily understood by patients. A core group of physicians and patients involved in the elaboration of the T2T recommendations produced a draft version of the T2T recommendations in lay language. This version was discussed, changed and r...

journal_title：Annals of the rheumatic diseases

authors： de Wit MP,Smolen JS,Gossec L,van der Heijde DM

更新日期：2011-06-01 00:00:00

abstract：OBJECTIVE:The expression of antinuclear antibodies (ANA) is considered almost constant in systemic lupus erythematosus (SLE), although recent experience has suggested that many subjects with SLE considered for clinical trials are ANA negative at screening. The objective of this study is to determine whether assay varia...

journal_title：Annals of the rheumatic diseases

authors： Pisetsky DS,Spencer DM,Lipsky PE,Rovin BH

更新日期：2018-06-01 00:00:00

abstract：OBJECTIVES:To review systematically the available literature on the optimal dosage and route of administration of methotrexate in patients with rheumatoid arthritis (RA), as an evidence base for generating clinical practice recommendations. METHODS:A systematic literature search was carried out in MEDLINE, EMBASE, Coc...

journal_title：Annals of the rheumatic diseases

authors： Visser K,van der Heijde D

更新日期：2009-07-01 00:00:00

abstract：:In order to evaluate the incidence and aetiology of hypergastrinaemia 53 patients with seropositive rheumatoid arthritis were examined for gastric acid secretion, fasting serum gastrin concentration, circulating parietal cell antibodies, and some parameters of the activity of inflammation of rheumatoid arthritis. The ...

journal_title：Annals of the rheumatic diseases

authors： de Witte TJ,Geerdink PJ,Lamers CB,Boerbooms AM,van der Korst JK

更新日期：1979-02-01 00:00:00

abstract：BACKGROUND:Whether preradiographic lesions in knees at risk for osteoarthritis are incidental versus disease is unclear. We hypothesised, in persons without but at higher risk for knee osteoarthritis, that: 12-48 month MRI lesion status worsening is associated with 12-48 month incident radiographic osteoarthritis (obje...

journal_title：Annals of the rheumatic diseases

authors： Sharma L,Nevitt M,Hochberg M,Guermazi A,Roemer FW,Crema M,Eaton C,Jackson R,Kwoh K,Cauley J,Almagor O,Chmiel JS

更新日期：2016-09-01 00:00:00

abstract：:Monoclonal antibodies have proved to be extremely valuable additions to conventional treatment for rheumatic diseases. However, despite the general trend towards "humanisation", these drugs remain immunogenic in clinical settings, baffling drug developers. In principle, humanised and fully human monoclonal antibodies ...

journal_title：Annals of the rheumatic diseases

authors： Scott DW,De Groot AS

更新日期：2010-01-01 00:00:00

abstract：OBJECTIVE:To study the association between silica exposure, separately as well as combined with smoking, and the risk of developing rheumatoid arthritis (RA) with or without the presence of antibodies against citrullinated peptide antigens (ACPA). METHODS:This Swedish population based case-control study analysed 577 i...

journal_title：Annals of the rheumatic diseases

authors： Stolt P,Yahya A,Bengtsson C,Källberg H,Rönnelid J,Lundberg I,Klareskog L,Alfredsson L,EIRA Study Group.

更新日期：2010-06-01 00:00:00

abstract：:An explant method for the isolation of fibroblasts from adult human tendon is described. Cells were successfully isolated from 22 out of 27 common biceps tendons obtained from cadaveric donors (age range 11-83 years). The fibroblasts could be maintained in culture using standard methods and morphologically resembled t...

journal_title：Annals of the rheumatic diseases

authors： Chard MD,Wright JK,Hazleman BL

更新日期：1987-05-01 00:00:00

abstract：OBJECTIVES:The prevalence and clinical outcomes of COVID-19 in patients with autoimmune diseases who are frequently treated with disease modifying therapies remains poorly understood. This meta-analysis aims to assess the prevalence and clinical outcomes of COVID-19 in autoimmune diseases. METHODS:Electronic databases...

journal_title：Annals of the rheumatic diseases

authors： Akiyama S,Hamdeh S,Micic D,Sakuraba A

更新日期：2020-10-13 00:00:00

abstract：OBJECTIVES:Interferon regulatory factor 5 (IRF5) is a member of the IRF family of transcription factors, which regulate the production of proinflammatory cytokines. Polymorphisms in the IRF5 gene have been associated with susceptibility to systemic lupus erythaematosus (SLE) in Caucasian and Asian populations, but thei...

journal_title：Annals of the rheumatic diseases

authors： Shimane K,Kochi Y,Yamada R,Okada Y,Suzuki A,Miyatake A,Kubo M,Nakamura Y,Yamamoto K

更新日期：2009-03-01 00:00:00

abstract：:In osteoarthritis (OA), adult articular chondrocytes undergo phenotypic modulation in response to alterations in the environment owing to mechanical injury and inflammation. These processes not only stimulate the production of enzymes that degrade the cartilage matrix but also inhibit repair. With the use of in vitro ...

journal_title：Annals of the rheumatic diseases

authors： Goldring MB,Otero M,Tsuchimochi K,Ijiri K,Li Y

更新日期：2008-12-01 00:00:00

abstract：OBJECTIVES:To investigate whether methotrexate or tumour necrosis factor inhibitors (TNFi) affect osteophyte formation in patients with psoriatic arthritis (PsA). METHODS:41 patients with PsA were examined for the presence of osteophytes and erosions at the metacarpophalangeal joints by high-resolution micro-CT imagin...

journal_title：Annals of the rheumatic diseases

authors： Finzel S,Kraus S,Schmidt S,Hueber A,Rech J,Engelke K,Englbrecht M,Schett G

更新日期：2013-07-01 00:00:00

abstract：:A 62 year old woman taking L-tryptophan developed eosinophilic fasciitis shortly after starting an exercise class. She received prednisone without benefit but improved after azathioprine treatment was started and L-tryptophan was discontinued. As products containing L-tryptophan have recently been implicated in develo...

journal_title：Annals of the rheumatic diseases

authors： Hamilton ME

更新日期：1991-01-01 00:00:00

abstract：OBJECTIVE:To investigate the effects of a switch from oral methotrexate (MTX) to subcutaneous MTX (scMTX) or adding ciclosporin to oral MTX with a simultaneous reduction of the MTX dose, in case of adverse events (AE) or insufficient effect (IE) in rheumatoid arthritis (RA). METHODS:The tight control treatment arm of ...

journal_title：Annals of the rheumatic diseases

authors： Bakker MF,Jacobs JW,Welsing PM,van der Werf JH,Linn-Rasker SP,van der Veen MJ,Lafeber FP,Bijlsma JW,Utrecht Arthritis Cohort Study Group.

更新日期：2010-10-01 00:00:00

abstract：:Gout and classical rheumatoid arthritis rarely coexist. We report a patient with strong evidence for both these diseases. Possible reasons for the negative correlation between these diseases are summarised. One hypothesis suggests inhibition of surface activity of monosodium urate crystals (MSU) by binding of rheumato...

journal_title：Annals of the rheumatic diseases

authors： Gordon TP,Ahern MJ,Reid C,Roberts-Thomson PJ

更新日期：1985-06-01 00:00:00