Thrombotic thrombocytopenic purpura and systemic lupus erythematosus.

abstract：OBJECTIVES:Increased numbers of neutrophils expressing proteinase 3 on their membrane (mPR3) have been reported in anti-neutrophil cytoplasm antibody (ANCA)-associated vasculitis (AAV) and are suggested to be involved in AAV immunopathogenesis. In most studies, neutrophils were analysed for mPR3 expression without prim...

journal_title：Annals of the rheumatic diseases

authors： van Rossum AP,Huitema MG,Stegeman CA,Bijl M,de Leeuw K,Van Leeuwen MA,Limburg PC,Kallenberg CG

更新日期：2007-10-01 00:00:00

abstract：:Previous work has suggested that prior poor reproductive outcome may be a risk factor in rheumatoid arthritis (RA). A case-control study of 195 women with RA and 462 control women from two different sources is presented here. No increase in rates of spontaneous abortion was seen in the women with RA; indeed a protecti...

journal_title：Annals of the rheumatic diseases

authors： Spector TD,Silman AJ

更新日期：1990-01-01 00:00:00

abstract：OBJECTIVE:To evaluate the efficacy and safety of combining monthly intravenous methotrexate (IV MTX) with monthly IV cyclophosphamide (CYTX; given on the same day) for the treatment of children who develop recurrent diffuse proliferative glomerulonephritis secondary to systemic lupus erythematosus during or after the s...

journal_title：Annals of the rheumatic diseases

authors： Lehman TJ,Edelheit BS,Onel KB

更新日期：2004-03-01 00:00:00

abstract：:Circulating immune complexes (CIC) were measured in 4 normal controls and 8 patients with systemic lupus erythematosus (SLE) by a polyethylene glycol precipitation (PEG) method during a 24-hour period. In all the normal controls levels fell during sleep and after drinking 1 pint (568 ml) of milk and rose before gettin...

journal_title：Annals of the rheumatic diseases

authors： Isenberg DA,Crisp AJ,Morrow WJ,Newham D,Snaith ML

更新日期：1981-10-01 00:00:00

abstract：OBJECTIVES:To see if a group course delivered by rheumatology teams using cognitive-behavioural approaches, plus usual care, reduced RA fatigue impact more than usual care alone. METHODS:Multicentre, 2-year randomised controlled trial in RA adults (fatigue severity>6/10, no recent major medication changes). RAFT (Redu...

journal_title：Annals of the rheumatic diseases

authors： Hewlett S,Almeida C,Ambler N,Blair PS,Choy EH,Dures E,Hammond A,Hollingworth W,Kadir B,Kirwan JR,Plummer Z,Rooke C,Thorn J,Turner N,Pollock J,RAFT Study Group.

更新日期：2019-04-01 00:00:00

abstract：:HLA types, especially HLA-DR3, are associated with the development of toxic reactions in patients with rheumatoid arthritis after treatment with gold or D-penicillamine. In this study, after treatment with sulphasalazine, leucopenia was observed in three patients, who all had a history of leucopenia after previous gol...

journal_title：Annals of the rheumatic diseases

authors： Bliddal H,Eiberg B,Helin P,Svejgaard A

更新日期：1989-07-01 00:00:00

abstract：BACKGROUND:Dendritic cells orchestrate pivotal immunological processes mediated by the production of cytokines and chemokines. OBJECTIVE:To assess whether neutralisation of tumour necrosis factor alpha (TNF alpha) during maturation of dendritic cells affects their phenotype and behaviour, which might explain the benef...

journal_title：Annals of the rheumatic diseases

authors： van Lieshout AW,Barrera P,Smeets RL,Pesman GJ,van Riel PL,van den Berg WB,Radstake TR

更新日期：2005-03-01 00:00:00

abstract：OBJECTIVE:To determine whether occurrence, characteristics, and progression of systemic lupus erythematosus (SLE) are associated with polymorphism of the mannose binding lectin (MBL) gene and with serum MBL concentration. METHODS:Codon 54 MBL gene polymorphism of 147 patients with SLE and 160 healthy controls was dete...

journal_title：Annals of the rheumatic diseases

authors： Takahashi R,Tsutsumi A,Ohtani K,Muraki Y,Goto D,Matsumoto I,Wakamiya N,Sumida T

更新日期：2005-02-01 00:00:00

abstract：OBJECTIVES:The balance between interferon gamma (IFN gamma) and interleukin 4 (IL4) producing T cells (T1 and T2 cells) seems to be of importance in many (auto)immune disorders. In general, T1 cell activity is important in cellular immunity whereas T2 cell activity plays a part in humoral responses. T1 cell activity pr...

journal_title：Annals of the rheumatic diseases

authors： Verhoef CM,van Roon JA,Vianen ME,Bruijnzeel-Koomen CA,Lafeber FP,Bijlsma JW

更新日期：1998-05-01 00:00:00

abstract：OBJECTIVES:To estimate the prevalence and incidence of systemic sclerosis (SSc) in southern Sweden. METHODS:In Skåne, the southernmost region of Sweden (total population 1.2 million), healthcare provided is registered in the Skåne Healthcare Register. We identified all Skåne residents who had received an International...

journal_title：Annals of the rheumatic diseases

authors： Andréasson K,Saxne T,Bergknut C,Hesselstrand R,Englund M

更新日期：2014-10-01 00:00:00

abstract：:The viscosity of plasma (PV) was investigated in 27 outpatients with classical or definite rheumatoid arthritis (RA) according to the American Rheumatism Association (ARA) criteria. The measurements showed a significantly raised PV in patients with RA (p less than 10(-5)) compared with a control group. There was a pos...

journal_title：Annals of the rheumatic diseases

authors： Harreby M,Danneskiold-Samsøe B,Kjer J,Lauritzen M

更新日期：1987-08-01 00:00:00

abstract：BACKGROUND:Many patients with rheumatoid arthritis are currently successfully treated with infliximab (anti-tumour necrosis factor); however, about 30% of the patients do not respond to infliximab. One of the postulated hypotheses of not responding is the fast clearance of infliximab due to the development of inflixima...

journal_title：Annals of the rheumatic diseases

authors： van der Laken CJ,Voskuyl AE,Roos JC,Stigter van Walsum M,de Groot ER,Wolbink G,Dijkmans BA,Aarden LA

更新日期：2007-02-01 00:00:00

abstract：:One hundred and two rural patients and 100 urban patients with rheumatoid arthritis and osteoarthrosis and 203 age and sex matched controls were visited in their homes to evaluate their problems, needs, and expectations. Although one would expect disability to affect the mobility of a person, it was found that rural p...

journal_title：Annals of the rheumatic diseases

authors： Cornelissen PG,Rasker JJ,Valkenburg HA

更新日期：1988-02-01 00:00:00

abstract：OBJECTIVE:To evaluate concentrations of the platelet activation markers beta thromboglobulin (BTG) and platelet factor 4 (PF4) in bronchoalveolar lavage fluid (BALF) from patients with systemic sclerosis with and without scleroderma interstitial lung disease (SLD). METHODS:BTG and PF-4 were measured by enzyme immunoas...

journal_title：Annals of the rheumatic diseases

authors： Kowal-Bielecka O,Kowal K,Lewszuk A,Bodzenta-Lukaszyk A,Walecki J,Sierakowski S

更新日期：2005-03-01 00:00:00

abstract：OBJECTIVE:In the present work, the frequency of inherited polymorphisms of the beta2 adrenergic receptor (beta2AR) gene and their association with rheumatoid arthritis (RA) as well as human leukocyte antigen (HLA)-DRB1 alleles was examined. METHODS:An allele-specific polymerase chain reaction was used to determine the...

journal_title：Annals of the rheumatic diseases

authors： Malysheva O,Pierer M,Wagner U,Wahle M,Wagner U,Baerwald CG

更新日期：2008-12-01 00:00:00

abstract：PURPOSE:To assess risk of cartilage loss in the tibiofemoral joint in relation to baseline damage severity, and to analyse the association of nearby pathologic findings on the risk of subsequent cartilage loss. METHODS:The Multicenter Osteoarthritis Study is a longitudinal study of individuals with or at high risk for...

journal_title：Annals of the rheumatic diseases

authors： Roemer FW,Felson DT,Wang K,Crema MD,Neogi T,Zhang Y,Nevitt MC,Marra MD,Lewis CE,Torner J,Guermazi A,MOST study investigators.

更新日期：2013-06-01 00:00:00

abstract：BACKGROUND:Although there has been major progress in gout imaging, no gout classification criteria currently include advanced imaging techniques. OBJECTIVE:To examine the usefulness of imaging modalities in the classification of gout when compared to monosodium urate (MSU) crystal confirmation as the gold standard, in...

journal_title：Annals of the rheumatic diseases

authors： Ogdie A,Taylor WJ,Weatherall M,Fransen J,Jansen TL,Neogi T,Schumacher HR,Dalbeth N

更新日期：2015-10-01 00:00:00

abstract：:HLA A, B, and C antigens were studied in 25 patients with ankylosing hyperostosis. There was no evidence of an increased frequency of any antigen in association with the condition itself. However, a high frequency of several antigens was found, reflecting the predominance of Jewish patients in the series. ...

journal_title：Annals of the rheumatic diseases

authors： Perry JD,Wolf H,Festenstein H,Storey GO

更新日期：1979-02-01 00:00:00

abstract：OBJECTIVES:To determine clinical and ultrasonographic predictors of joint replacement surgery across Europe in primary osteoarthritis (OA) of the knee. METHODS:This was a 3-year prospective study of a painful OA knee cohort (from a EULAR-sponsored, multicentre study). All subjects had clinical evaluation, radiographs ...

journal_title：Annals of the rheumatic diseases

authors： Conaghan PG,D'Agostino MA,Le Bars M,Baron G,Schmidely N,Wakefield R,Ravaud P,Grassi W,Martin-Mola E,So A,Backhaus M,Malaise M,Emery P,Dougados M

更新日期：2010-04-01 00:00:00

abstract：OBJECTIVE:A systematic literature review (SLR; 2009-2014) to compare a target-oriented approach with routine management in the treatment of rheumatoid arthritis (RA) to allow an update of the treat-to-target recommendations. METHODS:Two SLRs focused on clinical trials employing a treatment approach targeting a specifi...

journal_title：Annals of the rheumatic diseases

authors： Stoffer MA,Schoels MM,Smolen JS,Aletaha D,Breedveld FC,Burmester G,Bykerk V,Dougados M,Emery P,Haraoui B,Gomez-Reino J,Kvien TK,Nash P,Navarro-Compán V,Scholte-Voshaar M,van Vollenhoven R,van der Heijde D,Stamm TA

更新日期：2016-01-01 00:00:00

abstract：OBJECTIVE:To propose e-learning methods that address the fundamental problems related to sonographic training in rheumatology. METHODS:The project was designed for rheumatologists with strong motivation to learn ultrasound. A modular approach was constructed, consisting of a basic 3-day residential course, followed by...

journal_title：Annals of the rheumatic diseases

authors： Filippucci E,Meenagh G,Ciapetti A,Iagnocco A,Taggart A,Grassi W

更新日期：2007-07-01 00:00:00

abstract：OBJECTIVES:To investigate the hypothesis that synovial fluid (SF) from patients with osteoarthritis (OA) may contain calcium phosphate crystals that are either too small, or too few in number to be identified by conventional light microscopy techniques. METHODS:Twelve SF from 11 patients with established knee OA, five...

journal_title：Annals of the rheumatic diseases

authors： Swan A,Chapman B,Heap P,Seward H,Dieppe P

更新日期：1994-07-01 00:00:00

abstract：:The immune response against two herpesviruses has been determined in sera and matched synovial fluids of patients with rheumatoid arthritis (RA) and compared with that of a healthy control population. The increased level of antibody to Epstein-Barr virus (EBV) induced antigens in patients with RA resembles the antibod...

journal_title：Annals of the rheumatic diseases

authors： Musiani M,Zerbini M,Ferri S,Plazzi M,Gentilomi G,La Placa M

更新日期：1987-11-01 00:00:00

abstract：OBJECTIVES:To evaluate changes in bone mineral density (BMD) in the hands, hip and spine after 1 and 2 years of follow-up, in relation to antirheumatic and antiresorptive therapies and disease and demographic variables in patients with recent-onset rheumatoid arthritis (RA). METHODS:Changes in BMD measured in metacarp...

journal_title：Annals of the rheumatic diseases

authors： Güler-Yüksel M,Allaart CF,Goekoop-Ruiterman YP,de Vries-Bouwstra JK,van Groenendael JH,Mallée C,de Bois MH,Breedveld FC,Dijkmans BA,Lems WF

更新日期：2009-03-01 00:00:00

abstract：OBJECTIVES:The exact regulation of the synthesis of cartilage specific molecules, such as collagen type II and aggrecan, by articular chondrocytes is unknown, but growth factors and hormones probably play an important part. The effects of glucocorticosteroids (prednisolone and triamcinolone), in combination with insuli...

journal_title：Annals of the rheumatic diseases

authors： van der Kraan PM,Vitters EL,Postma NS,Verbunt J,van den Berg WB

更新日期：1993-10-01 00:00:00

abstract：BACKGROUND:The heteropolymer technology was developed to remove pathogens from the circulation. OBJECTIVES:To evaluate the safety and tolerability of a single administration and to establish proof of principle for ETI-104 in normal healthy volunteers (NHV) and patients with systemic lupus erythematosus (SLE) METHODS: ...

journal_title：Annals of the rheumatic diseases

authors： Iking-Konert C,Stocks S,Weinsberg F,Engelbrecht R,Bleck E,Perniok A,Fischer-Betz R,Pincus S,Nardone L,Schneider M

更新日期：2004-09-01 00:00:00

abstract：OBJECTIVES:Recent observational studies have highlighted the beneficial role of dairy ingestion in gout prevention. The aims of this study were to determine the acute effects of milk ingestion on serum urate concentrations and examine the mechanisms of these effects. METHODS:This was a short-term randomised controlled...

journal_title：Annals of the rheumatic diseases

authors： Dalbeth N,Wong S,Gamble GD,Horne A,Mason B,Pool B,Fairbanks L,McQueen FM,Cornish J,Reid IR,Palmano K

更新日期：2010-09-01 00:00:00

abstract：:Sixteen patients with classic rheumatoid arthritis (RA) complicated by severe vasculitis were studied and compared with a matched control group of 16 RA patients without vasculitis. Seven of the patients with vasculitis died within 4 to 120 months (median 32 months) after developing vasculitic symptoms. Gangrene of di...

journal_title：Annals of the rheumatic diseases

authors： Geirsson AJ,Sturfelt G,Truedsson L

更新日期：1987-10-01 00:00:00

abstract：OBJECTIVE:Pregnant women with systemic sclerosis (SSc; scleroderma) have an increased risk of premature delivery and small full-term infants. During placental development, angiogenesis and vascular remodelling are essential for a successful pregnancy outcome. An analysis was made of the pathological changes and express...

journal_title：Annals of the rheumatic diseases

authors： Ibba-Manneschi L,Manetti M,Milia AF,Miniati I,Benelli G,Guiducci S,Mecacci F,Mello G,Di Lollo S,Matucci-Cerinic M

更新日期：2010-02-01 00:00:00

abstract：OBJECTIVE:To study the association between silica exposure, separately as well as combined with smoking, and the risk of developing rheumatoid arthritis (RA) with or without the presence of antibodies against citrullinated peptide antigens (ACPA). METHODS:This Swedish population based case-control study analysed 577 i...

journal_title：Annals of the rheumatic diseases

authors： Stolt P,Yahya A,Bengtsson C,Källberg H,Rönnelid J,Lundberg I,Klareskog L,Alfredsson L,EIRA Study Group.

更新日期：2010-06-01 00:00:00