Ankylosing hyperostosis: a study of HLA A, B, and C antigens.

abstract：OBJECTIVES:The use of silicone implants in cosmetic and reconstructive surgery has been implicated in the development of autoimmune connective tissue diseases. Previous investigation of the influence of short-term silicone implantation using an experimental model of rheumatoid arthritis revealed no adverse influence up...

journal_title：Annals of the rheumatic diseases

authors： Schaefer CJ,Lawrence WD,Wooley PH

更新日期：1999-08-01 00:00:00

abstract：OBJECTIVE:Anticitrullinated protein antibodies (ACPA) are the most predictive factor for the development of rheumatoid arthritis (RA). Epitope spreading towards more citrullinated epitopes occurs before the onset of RA. Here, the authors investigated whether specific epitope recognition allows the identification of spe...

journal_title：Annals of the rheumatic diseases

authors： Willemze A,Böhringer S,Knevel R,Levarht EW,Stoeken-Rijsbergen G,Houwing-Duistermaat JJ,van der Helm-van Mil AH,Huizinga TW,Toes RE,Trouw LA

更新日期：2012-02-01 00:00:00

abstract：OBJECTIVES:Infectious agents like parvovirus have been implicated as exogenous factors that could trigger onset of systemic lupus erythematosus (SLE). A number of case reports describing a SLE-like presentation of acute human parvovirus B19 infection have been published, but no systematic investigation of the actual se...

journal_title：Annals of the rheumatic diseases

authors： Bengtsson A,Widell A,Elmstâhl S,Sturfelt G

更新日期：2000-01-01 00:00:00

abstract：:Human extensor tendons of the hand were pulled to rupture, and the torn ends, when observed in the scanning electron microscope, appeared to be knotted, possibly owing to the denaturation of the collagen. This confirmed by fluorimetry assays of both the ruptured ends and the middle unbroken sections of the same tendon...

journal_title：Annals of the rheumatic diseases

authors： Minns RJ,Steven FS

更新日期：1980-04-01 00:00:00

abstract：BACKGROUND:Increasing age at onset has been associated with worse outcome in rheumatoid arthritis, although there are few data from unselected inception cohorts. HYPOTHESIS:Increasing age is associated with a higher risk of erosions at presentation, and this increase is not explained by age-related disease confounders...

journal_title：Annals of the rheumatic diseases

authors： Bukhari M,Lunt M,Barton A,Bunn D,Silman A,Symmons D

更新日期：2007-03-01 00:00:00

abstract：:An investigation of cell-mediated cytotoxicity in 22 patients with systemic lupus erythematosus (SLE), using both whole blood and purified peripheral blood mononuclear cells (PBM) to measure antibody-dependent (ADCC) and phytohaemagglutinin (PHA)-induced lymphocyte cytotoxicity for Chang liver cells, has revealed 2 di...

journal_title：Annals of the rheumatic diseases

authors： Wright JK,Hughes P,Gelsthorpe K,Ward AM,Rowell NR

更新日期：1981-02-01 00:00:00

abstract：OBJECTIVES:Reverse cholesterol transport (RCT) is a major antiatherogenic function of high density lipoprotein (HDL). In the current work, the authors evaluated whether the RCT capacity of HDL from rheumatoid arthritis (RA) patients is impaired when compared to healthy controls. METHODS:HDL was isolated from 40 patien...

journal_title：Annals of the rheumatic diseases

authors： Charles-Schoeman C,Lee YY,Grijalva V,Amjadi S,FitzGerald J,Ranganath VK,Taylor M,McMahon M,Paulus HE,Reddy ST

更新日期：2012-07-01 00:00:00

abstract：:The relation between common rheumatic diseases such as osteoarthrosis, arthralgia without definite signs of osteoarthrosis, subacromial shoulder pain, different forms of tendinitis, low back pain and neck pain, and the level of formal education, occupational workload and some lifestyle factors were examined in 502 of ...

journal_title：Annals of the rheumatic diseases

authors： Jacobsson L,Lindgärde F,Manthorpe R,Ohlsson K

更新日期：1992-07-01 00:00:00

abstract：OBJECTIVE:To study the associations between structural abnormalities on ultrasound (US) or conventional x-rays (CR) and pain in hand osteoarthritis (HOA). METHODS:In 55 consecutive patients with HOA (mean age 61 years, 86% women) fulfilling the American College of Rheumatology criteria, pain in 30 separate hand joints...

journal_title：Annals of the rheumatic diseases

authors： Kortekaas MC,Kwok WY,Reijnierse M,Huizinga TW,Kloppenburg M

更新日期：2011-10-01 00:00:00

abstract：:Heart disease is a rare but important complication of polymyositis. Diagnosis of myocardial disease is usually based on non-specific clinical, electrocardiographic, and echocardiographic data. This paper reports a case of polymyositis with myocardial disease diagnosed by myocardial imaging with radiolabelled antibody ...

journal_title：Annals of the rheumatic diseases

authors： Le Guludec D,Lhote F,Weinmann P,Royer I,Jarrousse B,Caillat-Vigneron N,Guillevin L,Moretti JL

更新日期：1993-03-01 00:00:00

abstract：:The anti-inflammatory effect of single doses and combinations of aspirin and commonly used nonsteroidal anti-inflammatory drugs was investigated by the polyurethane sponge implantation model of acute inflammation. Dose response curves were performed to delineate a suppressive (high) and nonsuppressive (low) dose of ea...

journal_title：Annals of the rheumatic diseases

authors： Garrett R,Manthey B,Vernon-Roberts B,Brooks PM

更新日期：1983-08-01 00:00:00

abstract：OBJECTIVE:Rheumatoid arthritis (RA) accompanies infiltration and activation of monocytes in inflamed joints. We investigated dominant alterations of RA monocytes in bone marrow (BM), blood and inflamed joints. METHODS:CD14+ cells from BM and peripheral blood (PB) of patients with RA and osteoarthritis (OA) were profil...

journal_title：Annals of the rheumatic diseases

authors： Smiljanovic B,Radzikowska A,Kuca-Warnawin E,Kurowska W,Grün JR,Stuhlmüller B,Bonin M,Schulte-Wrede U,Sörensen T,Kyogoku C,Bruns A,Hermann S,Ohrndorf S,Aupperle K,Backhaus M,Burmester GR,Radbruch A,Grützkau A,Maslinski

更新日期：2018-02-01 00:00:00

abstract：:An 85 year old man with a longstanding history of non-tophaceous gout developed a single large tophus, unassociated with inflammation, on his paretic leg over a six week period following an acute hemiplegia. The rapidity of tophus formation, its localisation to the paretic limb, and the apparent blunting of the acute ...

journal_title：Annals of the rheumatic diseases

authors： Donegan CF,Berman P,Doherty M

更新日期：1993-04-01 00:00:00

abstract：:An explant method for the isolation of fibroblasts from adult human tendon is described. Cells were successfully isolated from 22 out of 27 common biceps tendons obtained from cadaveric donors (age range 11-83 years). The fibroblasts could be maintained in culture using standard methods and morphologically resembled t...

journal_title：Annals of the rheumatic diseases

authors： Chard MD,Wright JK,Hazleman BL

更新日期：1987-05-01 00:00:00

abstract：OBJECTIVE:The expression of antinuclear antibodies (ANA) is considered almost constant in systemic lupus erythematosus (SLE), although recent experience has suggested that many subjects with SLE considered for clinical trials are ANA negative at screening. The objective of this study is to determine whether assay varia...

journal_title：Annals of the rheumatic diseases

authors： Pisetsky DS,Spencer DM,Lipsky PE,Rovin BH

更新日期：2018-06-01 00:00:00

abstract：OBJECTIVE:To evaluate concentrations of the platelet activation markers beta thromboglobulin (BTG) and platelet factor 4 (PF4) in bronchoalveolar lavage fluid (BALF) from patients with systemic sclerosis with and without scleroderma interstitial lung disease (SLD). METHODS:BTG and PF-4 were measured by enzyme immunoas...

journal_title：Annals of the rheumatic diseases

authors： Kowal-Bielecka O,Kowal K,Lewszuk A,Bodzenta-Lukaszyk A,Walecki J,Sierakowski S

更新日期：2005-03-01 00:00:00

abstract：BACKGROUND:Low serum vitamin D concentrations have been reported in several autoimmune disorders. OBJECTIVE:To assess whether low serum vitamin D concentrations are related to disease activity of patients with systemic lupus erythematosus (SLE). METHODS:378 patients from several European and Israeli cohorts were pool...

journal_title：Annals of the rheumatic diseases

authors： Amital H,Szekanecz Z,Szücs G,Dankó K,Nagy E,Csépány T,Kiss E,Rovensky J,Tuchynova A,Kozakova D,Doria A,Corocher N,Agmon-Levin N,Barak V,Orbach H,Zandman-Goddard G,Shoenfeld Y

更新日期：2010-06-01 00:00:00

abstract：:An attempt was made to ascertain whether intra-articular corticosteroids exert a harmful effect on primate cartilage. The knee joints of 10 Macaca irus monkeys were subjected to either one, two, or six injections of 20 mg methyl prednisolone or an equal number of control injections over a 12-week period. Minor degener...

journal_title：Annals of the rheumatic diseases

authors： Gibson T,Burry HC,Poswillo D,Glass J

更新日期：1977-02-01 00:00:00

abstract：OBJECTIVE:To perform a prospective long term follow up study comparing conventional radiography (CR), ultrasonography (US), and magnetic resonance imaging (MRI) in the detection of bone erosions and synovitis in rheumatoid arthritis (RA) finger joints. METHODS:The metacarpophalangeal and proximal interphalangeal joint...

journal_title：Annals of the rheumatic diseases

authors： Scheel AK,Hermann KG,Ohrndorf S,Werner C,Schirmer C,Detert J,Bollow M,Hamm B,Müller GA,Burmester GR,Backhaus M

更新日期：2006-05-01 00:00:00

abstract：OBJECTIVE:To examine the association between body mass index (BMI) and osteoarthritis (OA) leading to total hip (THR) or knee (TKR) joint replacement. METHODS:Case-control study design. All patients still living in Iceland who had had a THR or TKR resulting from OA before the end of 2002 were invited to participate. F...

journal_title：Annals of the rheumatic diseases

authors： Franklin J,Ingvarsson T,Englund M,Lohmander LS

更新日期：2009-04-01 00:00:00

abstract：OBJECTIVE:Sacroiliitis is a hallmark of the spondyloarthropathies (SpA). The degree of inflammation can be quantified by magnetic resonance imaging (MRI). The aim of this study was to further elucidate the pathogenesis of SpA by quantitative cellular analysis of immunostained sacroiliac biopsy specimens and to compare ...

journal_title：Annals of the rheumatic diseases

authors： Bollow M,Fischer T,Reisshauer H,Backhaus M,Sieper J,Hamm B,Braun J

更新日期：2000-02-01 00:00:00

abstract：OBJECTIVE:FoxO3a is a transcriptional factor implicated in cell cycle regulation and apoptosis. Since rheumatoid arthritis (RA) is associated with apoptosis defects, the expression level, regulation and phosphorylation status of FoxO3a was investigated in blood and synovium from patients with RA. METHODS:In microarray...

journal_title：Annals of the rheumatic diseases

authors： Turrel-Davin F,Tournadre A,Pachot A,Arnaud B,Cazalis MA,Mougin B,Miossec P

更新日期：2010-04-01 00:00:00

abstract：OBJECTIVES:The aim of this study was to evaluate serum interleukin (IL) 12 concentration in patients with juvenile chronic arthritis (JCA), according to disease subtype, activity, and duration. IL12 has been demonstrated to prime the selective expansion of T helper (Th) cells with a Th1-type pattern of cytokine product...

journal_title：Annals of the rheumatic diseases

authors： Gattorno M,Picco P,Vignola S,Stalla F,Buoncompagni A,Pistoia V

更新日期：1998-07-01 00:00:00

abstract：OBJECTIVES:People with spondyloarthritis (SpA), ankylosing spondylitis (AS) and psoriatic arthritis (PsA) have identified the importance of understanding how their disease and its treatment impacts on their social roles. This requires a reliable and valid standardised measure, and this study evaluates these measurement...

journal_title：Annals of the rheumatic diseases

authors： Davis AM,Palaganas MP,Badley EM,Gladman DD,Inman RD,Gignac MA

更新日期：2011-10-01 00:00:00

abstract：BACKGROUND:Rheumatoid arthritis (RA), psoriatic arthritis (PsA) and other spondylarthritides impose a great impact on the individual in addition to the costs on society, which may be reduced by effective pharmacological treatment. Industry-independent health economic studies should complement studies sponsored by indus...

journal_title：Annals of the rheumatic diseases

authors： Gülfe A,Kristensen LE,Saxne T,Jacobsson LT,Petersson IF,Geborek P

更新日期：2010-02-01 00:00:00

abstract：OBJECTIVES:To study the reliability and construct validity of ultrasound in interphalangeal finger joints affected by erosive osteoarthritis (EOA) and non-EOA with MRI as the reference method. METHODS:252 joints were examined by ultrasound, conventional radiography and clinical examination. Ultrasound was performed us...

journal_title：Annals of the rheumatic diseases

authors： Wittoek R,Jans L,Lambrecht V,Carron P,Verstraete K,Verbruggen G

更新日期：2011-02-01 00:00:00

abstract：OBJECTIVE:Human bone marrow mesenchymal stromal cells (hBM-MSC) are being applied in tissue regeneration and treatment of autoimmune diseases (AD). Their cellular and immunophenotype depend on isolation and culture conditions which may influence their therapeutic application and reflect their in vivo biological functio...

journal_title：Annals of the rheumatic diseases

authors： Bocelli-Tyndall C,Trella E,Frachet A,Zajac P,Pfaff D,Geurts J,Heiler S,Barbero A,Mumme M,Resink TJ,Schaeren S,Spagnoli GC,Tyndall A

更新日期：2015-01-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:The Fc receptor-like 3 (FCRL3) gene -169T>C single nucleotide polymorphism (SNP) has been reported to be associated with several autoimmune diseases (AIDs) in Japanese populations. However, association results in other populations have been conflicting. Therefore, we investigated this SNP in a...

journal_title：Annals of the rheumatic diseases

authors： Eike MC,Nordang GB,Karlsen TH,Boberg KM,Vatn MH,IBSEN study group.,Dahl-Jørgensen K,Rønningen KS,Joner G,Flatø B,Bergquist A,Thorsby E,Førre O,Kvien TK,Undlien DE,Lie BA

更新日期：2008-09-01 00:00:00

abstract：OBJECTIVES:The objectives of this study were to determine whether late apoptotic cell material directly induces autoantibodies characteristic of systemic lupus erythematosus (SLE) and to investigate the innate recognition pathways involved. METHODS:B6, B6.MyD88(-/-), B6.TLR7(-/-) and B6.TLR9(-/-) mice were subcutaneou...

journal_title：Annals of the rheumatic diseases

authors： Pan ZJ,Maier S,Schwarz K,Azbill J,Akira S,Uematsu S,Farris AD

更新日期：2010-06-01 00:00:00

abstract：:The effects of dietary fatty acid supplementation on various disease parameters in the spontaneously autoimmune MRL-mp-lpr/lpr mouse model of systemic lupus erythematosus before onset of disease were investigated. A fat deficient diet was supplemented with the following oils: olive oil, sunflower oil, evening primrose...

journal_title：Annals of the rheumatic diseases

authors： Godfrey DG,Stimson WH,Watson J,Belch JF,Sturrock RD

更新日期：1986-12-01 00:00:00