Clinical and serological features of severe vasculitis in rheumatoid arthritis: prognostic implications.

abstract：OBJECTIVE:To evaluate the ability of ultrasound (US) to detect the presence and change of Achilles erosions in spondyloarthritis (SpA). METHODS:A blind prospective two-dimensional (2D) and three-dimensional (3D) US study of Achilles enthesis erosions in early SpA was undertaken. US examinations were performed at basel...

journal_title：Annals of the rheumatic diseases

authors： de Miguel E,Falcao S,Castillo C,Plasencia C,García M,Branco JC,Martín-Mola E

更新日期：2011-11-01 00:00:00

abstract：OBJECTIVE:To define the role of ultrasound (US) for the assessment of patients with rheumatoid arthritis (RA) in clinical remission, including joint and tendon evaluation. METHODS:A multicentre longitudinal study has been promoted by the US Study Group of the Italian Society for Rheumatology. 25 Italian centres partic...

journal_title：Annals of the rheumatic diseases

authors： Filippou G,Sakellariou G,Scirè CA,Carrara G,Rumi F,Bellis E,Adinolfi A,Batticciotto A,Bortoluzzi A,Cagnotto G,Caprioli M,Canzoni M,Cavatorta FP,De Lucia O,Di Sabatino V,Draghessi A,Farina I,Focherini MC,Gabba A,Guti

更新日期：2018-09-01 00:00:00

abstract：OBJECTIVE:To investigate whether type II collagen (CII) is recognised by oligoclonally expanded synovial T cells of patients with rheumatoid arthritis (RA). METHODS:Peripheral blood mononuclear cells (PBMC) from 15 RA patients were stimulated with CII in vitro. T cell clones expanded by such stimulation were compared ...

journal_title：Annals of the rheumatic diseases

authors： Sekine T,Kato T,Masuko-Hongo K,Nakamura H,Yoshino S,Nishioka K,Yamamoto K

更新日期：1999-07-01 00:00:00

abstract：OBJECTIVES:The relationship between radiographic evidence of osteoarthritis and knee pain has been weak. This may be because features that best discriminate knees with pain have not been included in analyses. We tested the correlation between knee pain and radiographic features taking into account both image analysis f...

journal_title：Annals of the rheumatic diseases

authors： Minciullo L,Parkes MJ,Felson DT,Cootes TF

更新日期：2018-11-01 00:00:00

abstract：OBJECTIVE:To test the hypothesis that pustulosis palmaris et plantaris and psoriatic arthritis (PsA) are two distinct diseases, and that the associated dermatoses are therefore also distinct diseases. METHODS:We prospectively performed clinical, radiological, biological, and bone scan investigations in 23 outpatients ...

journal_title：Annals of the rheumatic diseases

authors： Mejjad O,Daragon A,Louvel JP,Da Silva LF,Thomine E,Lauret P,Le Loët X

更新日期：1996-03-01 00:00:00

abstract：BACKGROUND:To investigate whether patients with primary Sjögren's syndrome (pSS) have an increased tendency to develop other autoimmune diseases. METHODS:A retrospective case note review was carried out on 114 patients in whom a diagnosis of pSS had been made in a department of rheumatology from 1979 onwards. The year...

journal_title：Annals of the rheumatic diseases

authors： Lazarus MN,Isenberg DA

更新日期：2005-07-01 00:00:00

abstract：OBJECTIVES:Systemic lupus erythematosus (SLE) is a serious multisystem autoimmune disease, mediated by disrupted B cell quiescence and typically treated with glucocorticoids. We studied whether B cells in SLE are regulated by the glucocorticoid-induced leucine zipper (GILZ) protein, an endogenous mediator of anti-infla...

journal_title：Annals of the rheumatic diseases

authors： Jones SA,Toh AE,Odobasic D,Oudin MA,Cheng Q,Lee JP,White SJ,Russ BE,Infantino S,Light A,Tarlinton DM,Harris J,Morand EF

更新日期：2016-04-01 00:00:00

abstract：:A three phase study was designed to define further the sensitivity and specificity of symptomatic salicylate ototoxicity (primarily tinnitus) for serum salicylate concentrations. In phase one 260 patients with osteoarthritis and 112 with rheumatoid arthritis, none taking salicylates, were interviewed about their ear s...

journal_title：Annals of the rheumatic diseases

authors： Halla JT,Atchison SL,Hardin JG

更新日期：1991-10-01 00:00:00

abstract：:Expression of insulin-like growth factor I (IGF-I)mRNA and IGF-I protein was studied in human osteoarthritic and young articular cartilage by in situ hybridisation and immunohistochemistry. In situ hybridisation showed that relatively low amounts of IGF-I mRNA signal were present in anatomically normal regions of oste...

journal_title：Annals of the rheumatic diseases

authors： Middleton JF,Tyler JA

更新日期：1992-04-01 00:00:00

abstract：OBJECTIVE:To evaluate the impact of tumour necrosis factor alpha (TNFalpha) blockers on the presence of liver fibrosis in patients with rheumatoid arthritis (RA) and psoriatic arthritis (PsA) treated with methotrexate (MTX). METHODS:Participants were consecutive patients with RA and PsA who had undergone MTX treatment...

journal_title：Annals of the rheumatic diseases

authors： Seitz M,Reichenbach S,Möller B,Zwahlen M,Villiger PM,Dufour JF

更新日期：2010-06-01 00:00:00

abstract：OBJECTIVES:The aim of this report is to demonstrate pharmacokinetic (PK) and pharmacodynamic (PD) equivalence as well as similar efficacy, safety and immunogenicity between GP2013, a biosimilar rituximab, and innovator rituximab (RTX) in patients with rheumatoid arthritis (RA) with inadequate response or intolerance to...

journal_title：Annals of the rheumatic diseases

authors： Smolen JS,Cohen SB,Tony HP,Scheinberg M,Kivitz A,Balanescu A,Gomez-Reino J,Cen L,Zhu P,Shisha T

更新日期：2017-09-01 00:00:00

abstract：OBJECTIVE:To investigate the contributions towards hyperuricaemia of known risk factors, focusing on fractional (renal) clearance of urate (FCU) and variation in the ATP-binding cassette transporter, sub-family G 2 (ABCG2) gene. METHODS:The contributions of age, sex, ancestry, Q141K genotype for ABCG2, FCU, sugar-swee...

journal_title：Annals of the rheumatic diseases

authors： Kannangara DR,Phipps-Green AJ,Dalbeth N,Stamp LK,Williams KM,Graham GG,Day RO,Merriman TR

更新日期：2016-07-01 00:00:00

abstract：OBJECTIVES:To characterise and quantify the CD4+ CD25+ T cell population in patients with systemic lupus erythematosus (SLE) and to detect the possible influence of treatments and clinical manifestations. METHODS:Characterisation of CD25(low) and CD25(high) CD4+ T cells from healthy controls and from patients with SLE...

journal_title：Annals of the rheumatic diseases

authors： Suárez A,López P,Gómez J,Gutiérrez C

更新日期：2006-11-01 00:00:00

abstract：OBJECTIVES:To compare the efficacy and safety of lumiracoxib with placebo and celecoxib for osteoarthritis OA in a 13 week, multicentre, randomised, double blind study. METHODS:After a 37 day washout period for nonsteroidal antiinflammatory drugs, 1702 patients with knee OA were randomised to lumiracoxib 200 or 400 mg...

journal_title：Annals of the rheumatic diseases

authors： Tannenbaum H,Berenbaum F,Reginster JY,Zacher J,Robinson J,Poor G,Bliddal H,Uebelhart D,Adami S,Navarro F,Lee A,Moore A,Gimona A

更新日期：2004-11-01 00:00:00

abstract：OBJECTIVE:To evaluate the efficacy and safety of combining monthly intravenous methotrexate (IV MTX) with monthly IV cyclophosphamide (CYTX; given on the same day) for the treatment of children who develop recurrent diffuse proliferative glomerulonephritis secondary to systemic lupus erythematosus during or after the s...

journal_title：Annals of the rheumatic diseases

authors： Lehman TJ,Edelheit BS,Onel KB

更新日期：2004-03-01 00:00:00

abstract：OBJECTIVE:To investigate polymorphisms of both codon 54 allele and promoter variants of the mannose binding lectin (MBL) gene in patients with primary Sjögren's syndrome (SS). METHODS:Polymorphisms of codon 54 allele and promoter variants of the MBL gene in 104 patients with SS and 143 healthy controls were determined...

journal_title：Annals of the rheumatic diseases

authors： Wang ZY,Morinobu A,Kanagawa S,Kumagai S

更新日期：2001-05-01 00:00:00

abstract：OBJECTIVE:Compare the radiographic progression of ankylosing spondylitis (AS) patients treated with infliximab (INF) versus historical controls (Herne cohort, HC) never treated with tumour necrosis factor (TNF)-blockers over 8 years. METHODS:Patients were selected based on the availability of lateral cervical and lumb...

journal_title：Annals of the rheumatic diseases

authors： Baraliakos X,Haibel H,Listing J,Sieper J,Braun J

更新日期：2014-04-01 00:00:00

abstract：:A case of septic, histoplasmal monoarthritis of the knee in a leukaemic patient is described. Ketoconazole therapy failed to eliminate the infection, but after histoplasmosis was diagnosed prolonged therapy with amphotericin B was curative. ...

journal_title：Annals of the rheumatic diseases

authors： Jones PG,Rolston K,Hopfer RL

更新日期：1985-02-01 00:00:00

abstract：OBJECTIVE:To investigate the elastic properties of the ascending aorta in untreated patients with giant cell arteritis compared with age and sex matched normal controls. METHODS:Distensibility of the ascending aorta and aortic strain were measured in 22 patients with a recent diagnosis of giant cell arteritis (documen...

journal_title：Annals of the rheumatic diseases

authors： Margos PN,Moyssakis IE,Tzioufas AG,Zintzaras E,Moutsopoulos HM

更新日期：2005-02-01 00:00:00

abstract：OBJECTIVE:The eumusc.net project is an initiative founded by the European Community and the European League Against Rheumatism. One aim of the project was to facilitate equal standards for musculoskeletal health across Europe. The aim of this work-package was to develop patient-centred and consensus based standards of ...

journal_title：Annals of the rheumatic diseases

authors： Stoffer MA,Smolen JS,Woolf A,Ambrozic A,Berghea F,Boonen A,Bosworth A,Carmona L,Dougados M,de Wit M,Erwin J,Fialka-Moser V,Ionescu R,Keenan AM,Loza E,Moe RH,Greiff R,Olejnik P,Petersson IF,Rat AC,Rozman B,Strömb

更新日期：2015-06-01 00:00:00

abstract：OBJECTIVE:To evaluate salivary hyaluronic acid (HA) concentration in patients with primary Sjögren's syndrome (SS). METHODS:Salivary and serum HA concentrations were evaluated using a radiometric assay. Thirty nine patients with SS served as the study group and their results were compared with 19 patients having clini...

journal_title：Annals of the rheumatic diseases

authors： Tishler M,Yaron I,Shirazi I,Yaron M

更新日期：1998-08-01 00:00:00

abstract：:A novel, constitutively expressed and secreted interleukin 18 (IL18) binding protein (IL18BP) neutralises IL18. IL18BP shares many characteristics with soluble cytokine receptors of the IL1 family in that the protein exhibits specificity for IL18, belongs to the immunoglobulin-like class of receptors and has limited a...

journal_title：Annals of the rheumatic diseases

authors： Dinarello CA

更新日期：2000-11-01 00:00:00

abstract：OBJECTIVE:To assess the extent of calcium pyrophosphate dihydrate (CPP) crystal deposition and the distribution of affected sites, using ultrasonography (US), in patients affected by CPP deposition disease (CPPD). PATIENTS AND METHODS:42 consecutive patients affected by definite CPPD according to the McCarty criteria ...

journal_title：Annals of the rheumatic diseases

authors： Filippou G,Filippucci E,Tardella M,Bertoldi I,Di Carlo M,Adinolfi A,Grassi W,Frediani B

更新日期：2013-11-01 00:00:00

abstract：BACKGROUND:Diagnosis of active pulmonary and paranasal involvement in patients with Wegener's granulomatosis (WG) can be difficult. The diagnostic value of gallium-67 scintigraphy in WG is unclear. OBJECTIVE:To evaluate the added diagnostic value of gallium-67 scintigraphy in patients with WG with suspected granulomat...

journal_title：Annals of the rheumatic diseases

authors： Slart RH,Jager PL,Poot L,Piers DA,Tervaert JW,Stegeman CA

更新日期：2003-07-01 00:00:00

abstract：OBJECTIVES:Studies in rheumatoid arthritis (RA), osteoarthritis (OA) and mice with arthritis demonstrated tyrosine hydroxylase-positive (TH(+)) cells in arthritic synovium and parallel loss of sympathetic nerve fibres. The exact function of TH(+) cells and mode of TH induction are not known. METHODS:Synovial cells of ...

journal_title：Annals of the rheumatic diseases

authors： Jenei-Lanzl Z,Capellino S,Kees F,Fleck M,Lowin T,Straub RH

更新日期：2015-02-01 00:00:00

abstract：OBJECTIVES:Different prevalences of generalised osteoarthritis (GOA) in patients with knee and hip OA have been reported. The aim of this investigation was to evaluate radiographic and clinical patterns of disease in a hospital based population of patient subgroups with advanced hip and knee OA and to compare the preva...

journal_title：Annals of the rheumatic diseases

authors： Günther KP,Stürmer T,Sauerland S,Zeissig I,Sun Y,Kessler S,Scharf HP,Brenner H,Puhl W

更新日期：1998-12-01 00:00:00

abstract：:Ten patients (8 female, 2 male) with systemic lupus erythematosus (SLE) were entered into an open trial with the anabolic steroid 19-nortestosterone (19-nor). Their clinical condition did not improve, nor were significant changes observed in the majority of laboratory data. However, overall the platelet count rose, an...

journal_title：Annals of the rheumatic diseases

authors： Hazelton RA,McCruden AB,Sturrock RD,Stimson WH

更新日期：1983-04-01 00:00:00

abstract：BACKGROUND:Suicide and suicide attempts, although well recognised in patients with systemic lupus erythematosus (SLE), have been commented on relatively little. OBJECTIVE:To obtain a better understanding of the reasons for suicidal behaviour in patients with SLE. METHODS:The records of 300 patients with SLE were revi...

journal_title：Annals of the rheumatic diseases

authors： Karassa FB,Magliano M,Isenberg DA

更新日期：2003-01-01 00:00:00

abstract：:We showed previously that the attachment of synovial fibroblasts to laminin (LM)-111 in the presence of transforming growth factor-beta induces significant expression of the matrix metalloproteinase (MMP)-3. Here we go on to investigate the regulation of additional MMPs and their specific tissue inhibitors of matrix p...

journal_title：Annals of the rheumatic diseases

authors： Warstat K,Pap T,Klein G,Gay S,Aicher WK

更新日期：2008-04-01 00:00:00

abstract：BACKGROUND:Previous data have shown that etanercept levels are associated with clinical response in rheumatoid arthritis. However, for ankylosing spondylitis (AS), data regarding this topic are inconclusive. OBJECTIVES:To investigate the relationship between etanercept levels and clinical response in patients with AS....

journal_title：Annals of the rheumatic diseases

authors： Kneepkens EL,Krieckaert CL,van der Kleij D,Nurmohamed MT,van der Horst-Bruinsma IE,Rispens T,Wolbink GJ

更新日期：2015-10-01 00:00:00