Evidence for treating rheumatoid arthritis to target: results of a systematic literature search update.

abstract：OBJECTIVE:Gout, the most common inflammatory arthritis, is associated with premature mortality. Whether this mortality gap has improved over time, as observed in rheumatoid arthritis (RA), is unknown. METHODS:Using an electronic medical record database representative of the UK general population, we identified inciden...

journal_title：Annals of the rheumatic diseases

authors： Fisher MC,Rai SK,Lu N,Zhang Y,Choi HK

更新日期：2017-07-01 00:00:00

abstract：:The effect of intranasal salmon calcitonin on pain, erosion progression, and bone loss in 40 women with rheumatoid arthritis was investigated. The study design was double blind, placebo controlled for the first four months and open for the next 36 months, allowing for cross over to active drug treatment or to the cont...

journal_title：Annals of the rheumatic diseases

authors： Sileghem A,Geusens P,Dequeker J

更新日期：1992-06-01 00:00:00

abstract：OBJECTIVE:Technetium-99m ethyl cysteinate dimer (99mTc ECD) single photon emission computed tomography (SPECT) of the brain was used to detect abnormal regional cerebral blood flow (rCBF) in patients with primary Sjögren's syndrome (pSS) and normal findings on brain magnetic resonance imaging (MRI). METHODS:(99m)Tc EC...

journal_title：Annals of the rheumatic diseases

authors： Chang CP,Shiau YC,Wang JJ,Ho ST,Kao A

更新日期：2002-09-01 00:00:00

abstract：:A 33-year-old male with definite Behçet's disease had rheumatoid-like nodules at his elbows. This finding, we believe, represents another manifestation of vasculitis in Behçet's disease. ...

journal_title：Annals of the rheumatic diseases

authors： Yurdakul S,Yazici H,Tüzüner N,Aytac S,Müftüoğlu AU

更新日期：1981-04-01 00:00:00

abstract：:Of 29 524 hospitalised medical patients monitored in a drug surveillance programme 1835 (6.2%) received the xanthine oxidase inhibitor allopurinol. After the exclusion of skin reactions adverse effects were attributed to this drug in 33 (1.8%) patients, the most frequent being haematological abnormalities (11 patients...

journal_title：Annals of the rheumatic diseases

authors： McInnes GT,Lawson DH,Jick H

更新日期：1981-06-01 00:00:00

abstract：OBJECTIVES:To compare the risk of keratinoctye skin cancer (basal cell carcinoma (BCC) and squamous cell carcinoma (SCC)) in patients treated for rheumatoid arthritis (RA) compared with the general population, and to determine whether anti-tumour necrosis factor (TNF) therapy exacerbates this risk. METHODS:Patients wi...

journal_title：Annals of the rheumatic diseases

authors： Mercer LK,Green AC,Galloway JB,Davies R,Lunt M,Dixon WG,Watson KD,British Society for Rheumatology Biologics Register Control Centre Consortium.,Symmons DP,Hyrich KL,British Society for Rheumatology Biologics Register.

更新日期：2012-06-01 00:00:00

abstract：:The performance of four different assays for circulating immune complexes-the C1q solid phase method, one using protein A and one using anti-IgG, C1q PEG, and the 2% PEG method-were compared in 61 patients with early rheumatoid arthritis followed up for two years. There were weak but statistically significant correlat...

journal_title：Annals of the rheumatic diseases

authors： Reeback JS,Silman AJ,Holborow EJ,Maini RN,Hay FC

更新日期：1985-02-01 00:00:00

abstract：:A patient with systemic lupus erythematosus was first diagnosed after she had developed the Budd-Chiari syndrome. We believe that the Budd-Chiari syndrome was part of her tendency for thrombosis, induced by the presence of a lupus anticoagulant. The association between enhanced thrombosis and the lupus anticoagulant i...

journal_title：Annals of the rheumatic diseases

authors： Averbuch M,Levo Y

更新日期：1986-05-01 00:00:00

abstract：:Antibiotic treatment of all disease manifestations after infection with Borrelia sensu lato spp aims at resolving the presenting disease manifestation and preventing late stage disease. The goals are resolution of the preventing manifestation and prevention of the spread of bacteria to prevent late disease like arthri...

journal_title：Annals of the rheumatic diseases

authors： Dinser R,Jendro MC,Schnarr S,Zeidler H

更新日期：2005-04-01 00:00:00

abstract：OBJECTIVE:To investigate the prediction of the postpartum onset of rheumatoid arthritis (RA). METHODS:Two thousand five hundred and forty seven healthy pregnant subjects were examined prospectively and the relation between serum rheumatoid factors (RF) and postpartum onset of RA was observed. Rheumatoid factors were m...

journal_title：Annals of the rheumatic diseases

authors： Iijima T,Tada H,Hidaka Y,Yagoro A,Mitsuda N,Kanzaki T,Murata Y,Amino N

更新日期：1998-08-01 00:00:00

abstract：OBJECTIVE:Progranulin (PGRN) was previously isolated as an osteoarthritis (OA)-associated growth factor. Additionally, PGRN was found to play a therapeutic role in inflammatory arthritis mice models through antagonising tumour necrosis factor α (TNF-α). This study was aimed at investigating the role of PGRN in degradat...

journal_title：Annals of the rheumatic diseases

authors： Zhao YP,Liu B,Tian QY,Wei JL,Richbourgh B,Liu CJ

更新日期：2015-12-01 00:00:00

abstract：BACKGROUND:Antenatal and postnatal treatment with dexamethasone (DEX) may negatively affect the neuropsychological development in children. Maternal anti-Ro/Sjögren's syndrome A (SSA) antibodies may also be associated with learning disabilities in offspring. OBJECTIVE:To assess neuropsychological development in babies...

journal_title：Annals of the rheumatic diseases

authors： Brucato A,Astori MG,Cimaz R,Villa P,Li Destri M,Chimini L,Vaccari R,Muscarà M,Motta M,Tincani A,Neri F,Martinelli S

更新日期：2006-11-01 00:00:00

abstract：OBJECTIVE:To estimate the incidence and consultation rate of lower extremity complaints in general practice. METHODS:Data were obtained from the Second Dutch National Survey of General Practice, in which 195 general practitioners (GPs) in 104 practices recorded all contacts with patients during 12 consecutive months i...

journal_title：Annals of the rheumatic diseases

authors： van der Waal JM,Bot SD,Terwee CB,van der Windt DA,Schellevis FG,Bouter LM,Dekker J

更新日期：2006-06-01 00:00:00

abstract：BACKGROUND:Interferon (IFN) beta displays anti-inflammatory and immunosuppressive activity and has been considered for the treatment of rheumatoid arthritis (RA). Information about the effects of this molecule on joint cells is scarce, however. OBJECTIVE:To investigate the effects of IFNbeta on the production of inter...

journal_title：Annals of the rheumatic diseases

authors： Palmer G,Mezin F,Juge-Aubry CE,Plater-Zyberk C,Gabay C,Guerne PA

更新日期：2004-01-01 00:00:00

abstract：:Twenty-five patients (22 males and 3 females) are described who had 'unclassifiable' seronegative peripheral arthritis affecting mainly the large joints of the lower limbs with other typical features of spondyloarthropathies such as heel pain, low back pain, and mucosal ulcers. But their disorders could not be diagnos...

journal_title：Annals of the rheumatic diseases

authors： Prakash S,Mehra NK,Bhargava S,Malaviya AN

更新日期：1983-12-01 00:00:00

abstract：:The early changes (five weeks) in the structure of newly synthesised and endogenous articular cartilage sulphated proteoglycans were studied in lapine IgG induced experimental immune synovitis. Rabbits with immune synovitis (IS-IgG) were compared with animals with a developed hypersensitivity to IgG (I-IgG) and with n...

journal_title：Annals of the rheumatic diseases

authors： Malemud CJ,Yoo JU,Goldberg VM,Kresina TF

更新日期：1987-07-01 00:00:00

abstract：:A simple method is described which allows sequential monitoring of the endocytic activity of blood and synovial fluid cells from rheumatoid arthritis patients undergoing therapy with levamisole. Evidence of immediate (24 hours) and long-term (5-7 weeks) cellular phagocytic enhancement is presented. ...

journal_title：Annals of the rheumatic diseases

authors： Wynne KM,Dieppe PA,Scott J,Huskisson EC

更新日期：1981-08-01 00:00:00

abstract：OBJECTIVE:To compare the efficacy and safety between tocilizumab added to methotrexate and tocilizumab switched from methotrexate in patients with active rheumatoid arthritis (RA). METHODS:This is a 2-year randomised, controlled study. RA patients with moderate or high disease activity despite methotrexate were random...

journal_title：Annals of the rheumatic diseases

authors： Kaneko Y,Atsumi T,Tanaka Y,Inoo M,Kobayashi-Haraoka H,Amano K,Miyata M,Murakawa Y,Yasuoka H,Hirata S,Nagasawa H,Tanaka E,Miyasaka N,Yamanaka H,Yamamoto K,Takeuchi T

更新日期：2016-11-01 00:00:00

abstract：:Lornoxicam is a new non-steroidal anti-inflammatory agent (NSAID) with a similar pharmacological profile to other oxicams and a potency 10 times greater than piroxicam. A multicentre, randomised, double blind, parallel group study was undertaken to compare the efficacy and tolerance of four weeks' treatment with lorno...

journal_title：Annals of the rheumatic diseases

authors： Berry H,Bird HA,Black C,Blake DR,Freeman AM,Golding DN,Hamilton EB,Jayson MI,Kidd B,Kohn H

更新日期：1992-02-01 00:00:00

abstract：OBJECTIVE:Notch signalling pathways are critical for angiogenesis and endothelial cell (EC) fate; however the mechanisms regulating these processes in the inflamed joint remain to be elucidated. Here, we examine whether Notch signalling mediates vascular endothelial growth factor (VEGF) and angiopoietin 2 (Ang2)-induce...

journal_title：Annals of the rheumatic diseases

authors： Gao W,Sweeney C,Walsh C,Rooney P,McCormick J,Veale DJ,Fearon U

更新日期：2013-06-01 00:00:00

abstract：:The circulating levels of hyaluronate were determined in 36 patients with scleroderma and in 36 control subjects matched for age and sex. The mean serum hyaluronate concentration in patients with progressive systemic sclerosis (n = 25) was 131 +/- 67 (SD) microgram/l and significantly greater (p less than 0.001) than ...

journal_title：Annals of the rheumatic diseases

authors： Engström-Laurent A,Feltelius N,Hällgren R,Wasteson A

更新日期：1985-09-01 00:00:00

abstract：:In a search for aspects of behaviour related to oral contraceptive use which might explain the favourable effect of oral contraception on the onset of rheumatoid arthritis (RA), cigarette smoking and alcohol consumption were studied as possible risk factors. Information on cigarette smoking and alcohol consumption was...

journal_title：Annals of the rheumatic diseases

authors： Hazes JM,Dijkmans BA,Vandenbroucke JP,de Vries RR,Cats A

更新日期：1990-12-01 00:00:00

abstract：OBJECTIVE:To identify differentially expressed genes in peripheral blood mononuclear cells (PBMCs) from patients with ankylosing spondylitis (AS) compared with healthy individuals. METHODS:RNA was extracted from PBMCs collected from 18 patients with active disease and 18 gender-matched and age-matched controls. Expres...

journal_title：Annals of the rheumatic diseases

authors： Duan R,Leo P,Bradbury L,Brown MA,Thomas G

更新日期：2010-09-01 00:00:00

abstract：OBJECTIVES:The impact of immunosuppression on postoperative outcomes has primarily been studied in patients undergoing joint replacement surgery. We aimed to evaluate the impact of biologics and glucocorticoids on outcomes after other major surgeries. METHODS:This retrospective cohort study used Medicare data 2006-201...

journal_title：Annals of the rheumatic diseases

authors： George MD,Baker JF,Winthrop KL,Goldstein SD,Alemao E,Chen L,Wu Q,Xie F,Curtis JR

更新日期：2020-05-01 00:00:00

abstract：:Expression of insulin-like growth factor I (IGF-I)mRNA and IGF-I protein was studied in human osteoarthritic and young articular cartilage by in situ hybridisation and immunohistochemistry. In situ hybridisation showed that relatively low amounts of IGF-I mRNA signal were present in anatomically normal regions of oste...

journal_title：Annals of the rheumatic diseases

authors： Middleton JF,Tyler JA

更新日期：1992-04-01 00:00:00

abstract：:Thermography before and after joint irrigation at arthroscopy showed no significant improvement of inflammation in 14 patients. Subjectively, those with chondrocalcinosis did best. ...

journal_title：Annals of the rheumatic diseases

authors： Bird HA,Ring EF

更新日期：1978-02-01 00:00:00

abstract：OBJECTIVES:To compare the prevalence of osteoarthritis (OA) of the hip, tibiofemoral and patellofemoral joints in a skeletal population. METHODS:A total of 785 adult English skeletons (695 Saxon or Mediaeval origin) were examined for OA using established criteria. RESULTS:Twenty nine skeletons had hip OA, compared wi...

journal_title：Annals of the rheumatic diseases

authors： Rogers J,Dieppe P

更新日期：1994-09-01 00:00:00

abstract：OBJECTIVE:To evaluate changes in baseline patient characteristics and entry criteria of randomised, controlled studies of tumour necrosis factor alpha (TNFα) inhibitors in rheumatoid arthritis (RA) patients. METHODS:A systematic literature review was performed using predefined inclusion criteria to identify randomised...

journal_title：Annals of the rheumatic diseases

authors： Rahman MU,Buchanan J,Doyle MK,Hsia EC,Gathany T,Parasuraman S,Aletaha D,Matteson EL,Conaghan PG,Keystone E,van der Heijde D,Smolen JS

更新日期：2011-09-01 00:00:00

abstract：OBJECTIVES:To compare levels of disability of people with and without hip and knee arthroplasty in a random national sample. METHODS:In 1999 a screening questionnaire to classify people into groups of increasing probabilities of disability was sent to 417 500 people; response rate 86%. The study population was obtaine...

journal_title：Annals of the rheumatic diseases

authors： Boutron I,Poiraudeau S,Ravaud JF,Baron G,Revel M,Nizard R,Dougados M,Ravaud P

更新日期：2003-08-01 00:00:00

abstract：:A 57 year old white man with aortic insufficiency and previously undiagnosed ankylosing spondylitis, who developed subacute bacterial endocarditis (SBE), is described. Emergency aortic valve replacement was necessary, and the aortic valve pathology showed diffusely fibrosed and thickened valve leaflets with bacterial ...

journal_title：Annals of the rheumatic diseases

authors： Hoppmann RA,Wise CM,Challa VR,Peacock JE

更新日期：1988-05-01 00:00:00