Treating rheumatoid arthritis to target: the patient version of the international recommendations.

abstract：OBJECTIVE:To evaluate the genetic influence of PvuII and XbaI polymorphisms of oestrogen receptor alpha (ORalpha) in patients with systemic lupus erythematosus (SLE) in Korea. METHODS:Genomic DNA from 268 female controls and 137 female SLE patients (41 childhood onset and 96 adult onset) were analysed using PvuII and ...

journal_title：Annals of the rheumatic diseases

authors： Lee YJ,Shin KS,Kang SW,Lee CK,Yoo B,Cha HS,Koh EM,Yoon SJ,Lee J

更新日期：2004-10-01 00:00:00

abstract：OBJECTIVE:To investigate changes in the levels of circulating cytokines with a focus on the Th1/Th2 balance during and after pregnancy in patients with rheumatoid arthritis (RA), juvenile idiopathic arthritis (JIA), and ankylosing spondylitis (AS). METHODS:Plasma and serum samples of 34 pregnant patients, 19 with RA, ...

journal_title：Annals of the rheumatic diseases

authors： Østensen M,Förger F,Nelson JL,Schuhmacher A,Hebisch G,Villiger PM

更新日期：2005-06-01 00:00:00

abstract：:Leucopenia appears to be a more frequent complication of sulphasalazine treatment in rheumatoid arthritis than in inflammatory bowel disease and poses a management problem. In this study leucopenia was found in 20 patients, 14 of whom were participating in prospective studies (252 patients), giving an incidence of 5.6...

journal_title：Annals of the rheumatic diseases

authors： Marabani M,Madhok R,Capell HA,Hunter JA

更新日期：1989-06-01 00:00:00

abstract：:A 33-year-old male with definite Behçet's disease had rheumatoid-like nodules at his elbows. This finding, we believe, represents another manifestation of vasculitis in Behçet's disease. ...

journal_title：Annals of the rheumatic diseases

authors： Yurdakul S,Yazici H,Tüzüner N,Aytac S,Müftüoğlu AU

更新日期：1981-04-01 00:00:00

abstract：:Superantigens are bacterial, viral, or retroviral proteins which can activate specifically a large proportion of T cells. In contrast with classical peptide antigen recognition, superantigens do not require processing to small peptides but act as complete or partially processed proteins. They can bind to major histoco...

journal_title：Annals of the rheumatic diseases

authors： Acha-Orbea H

更新日期：1993-03-01 00:00:00

abstract：OBJECTIVE:To measure Proteus mirabilis and Escherichia coli antibody levels in patients with rheumatoid arthritis (RA) during treatment by vegetarian diet. METHODS:Sera were collected from 53 RA patients who took part in a controlled clinical trial of fasting and a one year vegetarian diet. P mirabilis and E coli anti...

journal_title：Annals of the rheumatic diseases

authors： Kjeldsen-Kragh J,Rashid T,Dybwad A,Sioud M,Haugen M,Førre O,Ebringer A

更新日期：1995-03-01 00:00:00

abstract：:An investigation of cell-mediated cytotoxicity in 22 patients with systemic lupus erythematosus (SLE), using both whole blood and purified peripheral blood mononuclear cells (PBM) to measure antibody-dependent (ADCC) and phytohaemagglutinin (PHA)-induced lymphocyte cytotoxicity for Chang liver cells, has revealed 2 di...

journal_title：Annals of the rheumatic diseases

authors： Wright JK,Hughes P,Gelsthorpe K,Ward AM,Rowell NR

更新日期：1981-02-01 00:00:00

abstract：OBJECTIVE:To assess the impact of certolizumab pegol (CZP) on patient-reported outcomes (PROs) in rheumatoid arthritis (RA), and to interpret these results using number needed to treat (NNT), and associations between PRO responses and longer term outcomes. METHODS:A total of 619 patients with active RA were randomised...

journal_title：Annals of the rheumatic diseases

authors： Strand V,Smolen JS,van Vollenhoven RF,Mease P,Burmester GR,Hiepe F,Khanna D,Nikaï E,Coteur G,Schiff M

更新日期：2011-06-01 00:00:00

abstract：BACKGROUND:In 2001, the European League Against Rheumatism developed and disseminated the first guidelines for musculoskeletal (MS) ultrasound (US) in rheumatology. Fifteen years later, the dramatic expansion of new data on MSUS in the literature coupled with technological developments in US imaging has necessitated an...

journal_title：Annals of the rheumatic diseases

authors： Möller I,Janta I,Backhaus M,Ohrndorf S,Bong DA,Martinoli C,Filippucci E,Sconfienza LM,Terslev L,Damjanov N,Hammer HB,Sudol-Szopinska I,Grassi W,Balint P,Bruyn GAW,D'Agostino MA,Hollander D,Siddle HJ,Supp G,Schmidt W

更新日期：2017-12-01 00:00:00

abstract：OBJECTIVE:To prepare a website for families and health professionals containing up to date information about paediatric rheumatic diseases (PRD). METHODS:Firstly, paediatric rheumatology centres and family self help associations were surveyed to characterise current clinical practice of physicians providing care for c...

journal_title：Annals of the rheumatic diseases

authors： Ruperto N,Garcia-Munitis P,Villa L,Pesce M,Aggarwal A,Fasth A,Avcin T,Bae SC,Balogh Z,Li C,De Inocencio J,Dibra M,Dolezalova P,El Miedany Y,Flato B,Harjacek M,Huppertz HI,Kanakoudi-Tsakalidou F,Wulffraat N,Lahdenne

更新日期：2005-07-01 00:00:00

abstract：OBJECTIVES:The influence of dexamethasone on interleukin 10 (IL10) production and the type 1 (T1)/type 2 (T2) T cell balance found in rheumatoid arthritis (RA) was studied. METHODS:Peripheral blood mononuclear cells (PB MNC) were isolated from 14 RA patients both before and 7 and 42 days after high dose dexamethasone ...

journal_title：Annals of the rheumatic diseases

authors： Verhoef CM,van Roon JA,Vianen ME,Lafeber FP,Bijlsma JW

更新日期：1999-01-01 00:00:00

abstract：OBJECTIVE:To examine the effect of infliximab plus methotrexate (MTX) compared with placebo plus MTX on bone loss in patients with early rheumatoid arthritis (RA) in a double-blind randomised study design. Further, to explore the associations between bone loss and markers of RA disease. METHODS:All 20 patients with RA...

journal_title：Annals of the rheumatic diseases

authors： Haugeberg G,Conaghan PG,Quinn M,Emery P

更新日期：2009-12-01 00:00:00

abstract：OBJECTIVE:To test the hypothesis that pustulosis palmaris et plantaris and psoriatic arthritis (PsA) are two distinct diseases, and that the associated dermatoses are therefore also distinct diseases. METHODS:We prospectively performed clinical, radiological, biological, and bone scan investigations in 23 outpatients ...

journal_title：Annals of the rheumatic diseases

authors： Mejjad O,Daragon A,Louvel JP,Da Silva LF,Thomine E,Lauret P,Le Loët X

更新日期：1996-03-01 00:00:00

abstract：OBJECTIVE:To analyse matrix metalloproteinases (MMPs) and tissue inhibitor-1 of MMPs (TIMP-1) levels in the systemic circulation and synovial fluid (SF) of patients with RA and to compare these levels with inflammatory and collagen degradation markers. METHODS:ProMMP-1, -2, -3, -8, -9, TIMP-1, levels of MMP/alpha(2)-m...

journal_title：Annals of the rheumatic diseases

authors： Tchetverikov I,Ronday HK,Van El B,Kiers GH,Verzijl N,TeKoppele JM,Huizinga TW,DeGroot J,Hanemaaijer R

更新日期：2004-07-01 00:00:00

abstract：BACKGROUND:The Health Assessment Questionnaire Disability Index (HAQ-DI) is the most widely used measure of function in rheumatoid arthritis (RA). OBJECTIVE:To evaluate individualised forms of the HAQ-DI and thus enhance the incorporation of patients' views in outcome assessment. PATIENTS AND METHODS:HAQ-DI data were...

journal_title：Annals of the rheumatic diseases

authors： Seror R,Tubach F,Baron G,Guillemin F,Ravaud P

更新日期：2010-01-01 00:00:00

abstract：:The effect of immune complexes (IC) isolated from systemic lupus erythematosus (SLE) sera with polyethylene glycol and gel filtration on the chemotaxis and Fc receptor function of healthy monocytes was examined. Even at a low protein concentration (1 microgram/ml = 1 mg/l) ICs inhibit monocyte chemotaxis. ICs from pat...

journal_title：Annals of the rheumatic diseases

authors： Lukács K,Kávai M,Bányai A,Sonkoly I,Végh E,Szabó G,Szegedi G

更新日期：1984-10-01 00:00:00

abstract：:An attempt was made to ascertain whether intra-articular corticosteroids exert a harmful effect on primate cartilage. The knee joints of 10 Macaca irus monkeys were subjected to either one, two, or six injections of 20 mg methyl prednisolone or an equal number of control injections over a 12-week period. Minor degener...

journal_title：Annals of the rheumatic diseases

authors： Gibson T,Burry HC,Poswillo D,Glass J

更新日期：1977-02-01 00:00:00

abstract：OBJECTIVE:To explore the safety, efficacy, and lymphocyte activation of a triple therapeutic regimen with infliximab, methotrexate (MTX), and ciclosporin A (CsA) by an open label, pilot study. PATIENTS AND METHODS:19 patients (mean age 52.9 years) with active rheumatoid arthritis (mean DAS28 7.3) after a mean of 16.8 ...

journal_title：Annals of the rheumatic diseases

authors： Sidiropoulos PI,Siakka P,Raptopoulou A,Mamoulaki M,Choulaki C,Koutala H,Kouroumali H,Kritikos H,Boumpas DT

更新日期：2006-04-01 00:00:00

abstract：OBJECTIVES:This prospective study was designed to clarify the frequency, causes, and clinical course of renal disease in patients with early rheumatoid arthritis (RA). METHODS:235 patients (185 women, mean age 49.4 years) with early RA of less than one year's duration were enrolled and assessed monthly. Proteinuria wa...

journal_title：Annals of the rheumatic diseases

authors： Koseki Y,Terai C,Moriguchi M,Uesato M,Kamatani N

更新日期：2001-04-01 00:00:00

abstract：OBJECTIVE:To better understand the characteristics of synoviocytes located in the rheumatoid arthritis (RA) pannus. METHODS:One cell line, termed PSC, was cloned from RA pannus lesions. Phenotypic analysis was done by contrast microscopy, indirect immunostaining, and safranin O staining. Transcription of several proto...

journal_title：Annals of the rheumatic diseases

authors： Xue C,Takahashi M,Hasunuma T,Aono H,Yamamoto K,Yoshino S,Sumida T,Nishioka K

更新日期：1997-04-01 00:00:00

abstract：:Antibodies to histones (AHA) are commonly found in patients with systemic lupus erythematosus (SLE). However, the full profile of AHA and their clinical associations remains unclear. A total of 111 patients with SLE were studied, including 13 patients in whom multiple serum samples were available over several years. I...

journal_title：Annals of the rheumatic diseases

authors： Cohen MG,Pollard KM,Webb J

更新日期：1992-01-01 00:00:00

abstract：BACKGROUND:Rheumatoid arthritis (RA), psoriatic arthritis (PsA) and other spondylarthritides impose a great impact on the individual in addition to the costs on society, which may be reduced by effective pharmacological treatment. Industry-independent health economic studies should complement studies sponsored by indus...

journal_title：Annals of the rheumatic diseases

authors： Gülfe A,Kristensen LE,Saxne T,Jacobsson LT,Petersson IF,Geborek P

更新日期：2010-02-01 00:00:00

abstract：OBJECTIVE:To compare individually tailored, based on trimestrial biological parameter monitoring, to fixed-schedule rituximab reinfusion for remission maintenance of antineutrophil cytoplasm antibody (ANCA)-associated vasculitides (AAVs). METHODS:Patients with newly diagnosed or relapsing granulomatosis with polyangii...

journal_title：Annals of the rheumatic diseases

authors： Charles P,Terrier B,Perrodeau É,Cohen P,Faguer S,Huart A,Hamidou M,Agard C,Bonnotte B,Samson M,Karras A,Jourde-Chiche N,Lifermann F,Gobert P,Hanrotel-Saliou C,Godmer P,Martin-Silva N,Pugnet G,Matignon M,Aumaitre O,

更新日期：2018-08-01 00:00:00

abstract：:A 21-year-old woman developed persistent polyarthritis indistinguishable from rheumatoid arthritis after rubella. The arthritis persisted for approximately 30 months and was associated with high levels of antibody to rubella virus and with rheumatoid factor. The antibody titres declined pari passu with clinical improv...

journal_title：Annals of the rheumatic diseases

authors： McCormick JN,Duthie JJ,Gerber H,Hart H,Baker S,Marmion BP

更新日期：1978-06-01 00:00:00

abstract：:Decreased immunoglobulin production in pokeweed mitogen driven lymphocyte cultures has been reported in rheumatoid arthritis (RA). Here various activators and experimental designs have been used to determine the contribution of B cells, T cells, or monocytes to this low response. Sixty patients with RA and paired cont...

journal_title：Annals of the rheumatic diseases

authors： Jokinen I,Poikonen K,Möttönen T,Hannonen P,Oka M,Ilonen J,Surcel HM,Karttunen R,Arvilommi H

更新日期：1990-07-01 00:00:00

abstract：OBJECTIVE:Gout, the most common inflammatory arthritis, is associated with premature mortality. Whether this mortality gap has improved over time, as observed in rheumatoid arthritis (RA), is unknown. METHODS:Using an electronic medical record database representative of the UK general population, we identified inciden...

journal_title：Annals of the rheumatic diseases

authors： Fisher MC,Rai SK,Lu N,Zhang Y,Choi HK

更新日期：2017-07-01 00:00:00

abstract：OBJECTIVES:Annual echocardiography screening is widely used in scleroderma, but the utility of longitudinal assessment is unknown. We evaluated whether change in right ventricular systolic pressure (RVSP) was a risk factor for mortality and development of pulmonary arterial hypertension (PAH) in a cohort of scleroderma...

journal_title：Annals of the rheumatic diseases

authors： Shah AA,Chung SE,Wigley FM,Wise RA,Hummers LK

更新日期：2013-07-01 00:00:00

abstract：:There is no agreement as to which variable best mirrors disease activity in rheumatoid arthritis (RA) and no studies have been performed on the validity of disease activity variables. In this study the validity of 10 commonly used single variables and three composite indices was tested. All patients participated in a ...

journal_title：Annals of the rheumatic diseases

authors： van der Heijde DM,van't Hof MA,van Riel PL,van Leeuwen MA,van Rijswijk MH,van de Putte LB

更新日期：1992-02-01 00:00:00

abstract：:Sera from patients with rheumatoid arthritis (RA), patients with infectious mononucleosis (IM), and blood donors were tested by indirect immunofluorescence for the presence of antikeratin antibody (AKA), antibody to cytoskeletal intermediate filaments of prekeratin or vimentin type (AIFA) and antiperinuclear factor (A...

journal_title：Annals of the rheumatic diseases

authors： Kataaha PK,Mortazavi-Milani SM,Russell G,Holborow EJ

更新日期：1985-07-01 00:00:00

abstract：:Leishmaniasis is an intracellular protozoan infection that can lead to cutaneous, mucocutaneous, visceral or systemic manifestations depending on the parasite species and virulence and on the host immune response. It is endemic in countries of Europe (Mediterranean basin), Asia, Africa, Central and South America, but ...

journal_title：Annals of the rheumatic diseases

authors： Bogdan C

更新日期：2012-04-01 00:00:00