A study of the mechanisms involved in relaxation induced by 17-beta-estradiol in the isolated rabbit aorta.

Abstract:

:We used the isolated rabbit aorta to examine the mechanisms that mediate the known vasodilatation induced by 17-beta-estradiol. Our results suggest that nitric oxide (NO), the inhibition of Ca2+ release from intracellular stores through the IP3 pathway and Ca2+ influx through potential-dependent calcium channels (PDCs) seem to be involved. Prostaglandins and adrenergic beta receptors do not influx, intracellular Ca2+ release, NO, cyclic guanine monophosphate (cGMP), prostaglandins and adrenergic beta receptors.

journal_name

Arch Gynecol Obstet

authors

Li HF,Li W,Zheng TZ,Qu SY,Zhang CL

doi

10.1007/s004040100238

subject

Has Abstract

pub_date

2002-04-01 00:00:00

pages

101-4

issue

2

eissn

0932-0067

issn

1432-0711

journal_volume

266

pub_type

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