Abstract：
:Pregnancy-associated plasma protein A (PAPP-A) is a large glycoprotein produced mainly by the trophoblast during pregnancy and released into the maternal circulation. Its biological function is unknown. In the second trimester i.e. when Down syndrome (DS) screening is routinely performed, the level of maternal serum PAPP-A was found to be within the normal range in pregnancies affected by fetal trisomy 21. However, PAPP-A was shown to be a potent marker for DS before 14 weeks of gestation. Only radioimmunoassays (RIAs) based on labelled antigen competition reached the required sensitivity for early pregnancy PAPP-A determinations; but they have a very short shelf life due to inherent tracer half-life and, in the case of PAPP-A, instability of the labelled antigen after three weeks. We describe a convenient and novel enzyme immunoassay (ELISA) with high sensitivity and a long shelf life.
journal_name
Arch Gynecol Obstetjournal_title
Archives of gynecology and obstetricsauthors
Bersinger NA,Zakher A,Huber U,Pescia G,Schneider Hdoi
10.1007/BF00634490subject
Has Abstractpub_date
1995-01-01 00:00:00pages
185-92issue
4eissn
0932-0067issn
1432-0711journal_volume
256pub_type
杂志文章abstract：PURPOSE:To establish a reference range for the intracranial translucency (IT). METHODS:In this prospective study, we examined 596 singleton fetuses at 11-14 weeks of gestation using transabdominal ultrasonography. The distribution curves of the anterior-posterior diameter of the IT were established according to the ge...
journal_title：Archives of gynecology and obstetrics
pub_type： 杂志文章
doi：10.1007/s00404-014-3410-6
更新日期：2015-03-01 00:00:00
abstract：BACKGROUND:Recent studies show that contrast-enhanced ultrasonography (CEUS) using SonoVue has the potential to improve the performance of sentinel lymph node biopsy (SLNB) in patients with early breast cancer. However, the evidence of SLNB using CEUS in patients converting from cN1 to cN0 after neoadjuvant chemotherap...
journal_title：Archives of gynecology and obstetrics
pub_type： 杂志文章
doi：10.1007/s00404-020-05646-8
更新日期：2020-09-01 00:00:00
abstract：BACKGROUND:Zollinger Ellison syndrome (ZES), an ulcerative disease of the upper gastrointestinal tract that involves the production of high levels of gastrin and gastric acid, is a rare, symptomatic, endocrine neoplastic disease. CASE:We report a rare case of gastrinoma that was first diagnosed during pregnancy in whi...
journal_title：Archives of gynecology and obstetrics
pub_type： 杂志文章
doi：10.1007/s00404-007-0319-3
更新日期：2007-08-01 00:00:00
abstract：:Primary malignant tumors of the breast are the most frequently occurring neoplasms in women whereas breast metastases are rare. We report the first case, in literature, of metastasis within the breast resulting from a previous cecum carcinoma. We discuss the case and review the literature. ...
journal_title：Archives of gynecology and obstetrics
pub_type： 杂志文章,评审
doi：10.1007/s004040000158
更新日期：2001-11-01 00:00:00
abstract：OBJECTIVE:The objective of this research was to identify the rate of unexpected malignancies after laparoscopic-assisted supracervical hysterectomies (LASH) and describe the therapy regime. METHODS:The research is based on a retrospective chart analysis of patients undergoing a simple hysterectomy in the gynecological...
journal_title：Archives of gynecology and obstetrics
pub_type： 杂志文章
doi：10.1007/s00404-012-2559-0
更新日期：2013-03-01 00:00:00
abstract：PURPOSE:Giant oocytes are potential sources of chromosomal abnormalities and should thus never be used in in vitro fertilization and embryo transfer (IVF-ET) procedures. The presence of giant oocytes may indicate the efficiency of the ovarian stimulation and can refer to the quality of sibling oocytes. METHODS:IVF cyc...
journal_title：Archives of gynecology and obstetrics
pub_type： 杂志文章
doi：10.1007/s00404-015-3679-0
更新日期：2015-09-01 00:00:00
abstract：OBJECTIVE:This study aimed to determine the relationship between spousal deployment and postpartum depression diagnosis among U.S. military wives, accounting for the timing of deployment with respect to pregnancy and delivery. METHODS:A retrospective cohort study was conducted to evaluate the association between spous...
journal_title：Archives of gynecology and obstetrics
pub_type： 杂志文章
doi：10.1007/s00404-015-3672-7
更新日期：2015-09-01 00:00:00
abstract：PURPOSE:To identify key genes related to the effect of estrogen on ovarian cancer. METHODS:Microarray data (GSE22600) were downloaded from Gene Expression Omnibus. Eight estrogen and seven placebo treatment samples were obtained using a 2 × 2 factorial designs, which contained 2 cell lines (PEO4 and 2008) and 2 treatm...
journal_title：Archives of gynecology and obstetrics
pub_type： 杂志文章
doi：10.1007/s00404-015-3833-8
更新日期：2016-02-01 00:00:00
abstract：INTRODUCTION:Breast reconstruction with salpingo-oophorectomy can easily be performed in patients with genetic mutations increasing the risk for mammary and ovarian carcinoma. However, many patients are skeptical about having several surgeries, as they may result in additional anesthesiological risks as well as multipl...
journal_title：Archives of gynecology and obstetrics
pub_type： 杂志文章
doi：10.1007/s00404-013-3133-0
更新日期：2014-06-01 00:00:00
abstract：:The great 11th-12th century Persian physician Seyed Esmail Jorjani (known as Hakim Jorjani) is known for his 750,000 word encyclopedia of medicine, the Treasure of King Khwarazm, which has been ranked along with Avicenna's Canon and the works of Haly Abbas. Translations of this work provide modern readers with a detai...
journal_title：Archives of gynecology and obstetrics
pub_type： 传,历史文章,杂志文章
doi：10.1007/s00404-010-1707-7
更新日期：2011-09-01 00:00:00
abstract：PURPOSE:To investigate the accuracy of the soluble fms-like tyrosine kinase-1(sFlt-1)/placental growth factor (PlGF) ratio to predict preeclampsia (PE). METHODS:A search in the PubMed, Embase, and Cochrane Library was conducted for human studies without language restriction. We included the studies reported sufficient...
journal_title：Archives of gynecology and obstetrics
pub_type： 杂志文章,meta分析,评审
doi：10.1007/s00404-015-3671-8
更新日期：2015-09-01 00:00:00
abstract：PURPOSE:We sought to investigate the serum levels of asymmetric dimethylarginine in pregnant women with hyperemesis gravidarum. METHODS:Thirty-seven patients with hyperemesis gravidarum and 33 healthy controls were included in the study. Participants in the control group had no symptoms, or suffered only mild nausea w...
journal_title：Archives of gynecology and obstetrics
pub_type： 杂志文章
doi：10.1007/s00404-011-1982-y
更新日期：2012-02-01 00:00:00
abstract：:In the 72 h after a single oral dose of 400 mg of the antiprogesterone mifepristone, 12 out of 14 first and one second trimester fetuses had a slight increase in heart rate; 2 fetuses died and one aborted. During the same 72 h, uterine activity increased moderately, and was physiological with no increase in resting pr...
journal_title：Archives of gynecology and obstetrics
pub_type： 杂志文章
doi：10.1007/BF00931376
更新日期：1989-01-01 00:00:00
abstract：PURPOSE:To study the anti-oxidant properties of neem (Azadirachta indica) in inducing apoptosis of cervical cancer cells and estimation of caspase activity and TNF-α and IFN-γ levels in monocytes of cervical cancer patients and controls. METHODS:Monocytes were cultured from blood samples of 65 study cases and 30 contr...
journal_title：Archives of gynecology and obstetrics
pub_type： 杂志文章
doi：10.1007/s00404-012-2428-x
更新日期：2012-11-01 00:00:00
abstract：PURPOSE:To revisit risk factors of major obstetric hemorrhage in a large obstetric center. STUDY DESIGN:A retrospective case control study was conducted based on institutional electronic database and blood bank registry of a single center, 2005-2014. The major obstetric hemorrhage event was defined as transfusion of ≥...
journal_title：Archives of gynecology and obstetrics
pub_type： 杂志文章
doi：10.1007/s00404-015-3725-y
更新日期：2015-10-01 00:00:00
abstract：PURPOSE:Silencing of HPV oncogenes or their human host client proteins using topically applied small interfering RNA (siRNA) may be an attractive nonsurgical strategy for CIN treatment. An exploratory clinical investigation was designed to evaluate E6-AP mRNA expression levels in different stages of cervical intraepith...
journal_title：Archives of gynecology and obstetrics
pub_type： 杂志文章
doi：10.1007/s00404-013-3120-5
更新日期：2014-06-01 00:00:00
abstract：PURPOSE:To investigate whether complement and other immune-related proteins in cervicovaginal fluid (CVF) can predict intra-amniotic infection and/or inflammation (IAI) and spontaneous preterm delivery (SPTD, < 34.0 weeks) in women with preterm labor (PTL) and to compare the predictive abilities of these biomarkers wit...
journal_title：Archives of gynecology and obstetrics
pub_type： 杂志文章
doi：10.1007/s00404-020-05560-z
更新日期：2020-06-01 00:00:00
abstract：BACKGROUND:Despite the well-known second trimester ultrasound signs, current possibilities of in utero surgical repair of open spina bifida require a timely detection of the spine defect. OBJECTIVE:To evaluate the diagnostic accuracy of the ratio between brain stem (BS) diameter and its distance to the occipital bone ...
journal_title：Archives of gynecology and obstetrics
pub_type： 杂志文章,meta分析
doi：10.1007/s00404-019-05422-3
更新日期：2020-02-01 00:00:00
abstract：PURPOSE:Adenomyosis is a benign uterine disease resulting from the myometrial invasion of the endometrial gland and stroma. In the current study, angiogenesis, apoptosis and energy metabolism were investigated in adenomyosis. METHODS:A retrospective study was performed using paraffin archival tissues. Three groups wer...
journal_title：Archives of gynecology and obstetrics
pub_type： 杂志文章
doi：10.1007/s00404-020-05742-9
更新日期：2020-11-01 00:00:00
abstract：:In erythrocytes, the extrusion of a cellular sodium level load is accomplished by the Ouabain--sensitive Na+/K+ pump and by the furosemide-sensitive Na+/K(+)--cotransport, which operates against the passive sodium permeability. An abnormal low rate of net sodium extrusion by the Na+/K+ cotransport was observed in pre-...
journal_title：Archives of gynecology and obstetrics
pub_type： 杂志文章
doi：10.1007/BF02766642
更新日期：1993-01-01 00:00:00
abstract：BACKGROUND:Several attempts have been made to find tools for the prediction of successful induction of labor. Sonographic myometrial thickness has not yet been investigated regarding its use as a clinical tool for the course of labor induction. OBJECTIVE:To evaluate the role of sonographic measurement of myometrial th...
journal_title：Archives of gynecology and obstetrics
pub_type： 杂志文章
doi：10.1007/s00404-020-05811-z
更新日期：2020-09-29 00:00:00
abstract：:In spite of menstrual bleedings during premenopause FSH-concentration in blood increases significantly, however, without reaching post-menopausal amounts. Sometimes it is correlated with climacteric symptoms. FSH increases already 10 years before menopause, whereas LH does not change. Responsible for that is the parti...
journal_title：Archives of gynecology and obstetrics
pub_type： 杂志文章,评审
doi：10.1007/BF02417644
更新日期：1989-01-01 00:00:00
abstract：PURPOSE:In case of non-gynecological solid tumors and hematological malignancies diagnosed during pregnancy, individual diagnostic and treatment options must be established by an interdisciplinary team. METHODS:In part II of the present review we report on diagnostic and therapeutic principles in distinct entities of ...
journal_title：Archives of gynecology and obstetrics
pub_type： 杂志文章,评审
doi：10.1007/s00404-011-2059-7
更新日期：2011-12-01 00:00:00
abstract：:We studied the prognostic value of anaemia in the evolution of patients with early stages of uterine cervix cancer and treated with radical surgery. An observational study of 114 patients treated for cervical cancer at the "La Fe" Maternity Hospital in Valencia (Spain) during the period 1971 to 1989. Survival analyses...
journal_title：Archives of gynecology and obstetrics
pub_type： 杂志文章
doi：10.1007/s00404-002-0296-5
更新日期：2003-01-01 00:00:00
abstract：PURPOSE:To investigate the effect of vitamin D in ovarian hyperstimulation syndrome (OHSS). METHODS:In this animal study, 28 immature female Wistar rats were divided into four groups: group 1 (control); group 2 (ovarian stimulation); group 3 (OHSS group); group 4 (OHSS + vitamin D group). All groups were killed 48 h a...
journal_title：Archives of gynecology and obstetrics
pub_type： 杂志文章
doi：10.1007/s00404-015-3625-1
更新日期：2015-08-01 00:00:00
abstract：OBJECTIVE:To assess women's knowledge about female reproductive system and the demographic factors that may influence their perceptions. STUDY DESIGN:In this cross-sectional study, all qualifying adult women at our academic practice were asked to complete a self-administered anonymous questionnaire about the effects o...
journal_title：Archives of gynecology and obstetrics
pub_type： 杂志文章
doi：10.1007/s00404-013-3116-1
更新日期：2014-06-01 00:00:00
abstract：BACKGROUND:To validate the prediction equation of the volume of fetal cerebellum by three-dimensional ultrasonography determined for Taiwan's population in Brazilian population. METHODS:A longitudinal prospective study was performed with 52 normal pregnant women between 20 and 32 weeks. The measurement of fetal cerebe...
journal_title：Archives of gynecology and obstetrics
pub_type： 杂志文章
doi：10.1007/s00404-006-0192-5
更新日期：2007-01-01 00:00:00
abstract：PURPOSE:Color Doppler ultrasound (CDU) accuracy of kidneys and bladder in the diagnosis and treatment of hydronephrosis and/or renal colic in pregnancies was evaluated. METHODS:Between January 2010 and September 2012, 234 pregnant women asymptomatic in 204 cases and with unilateral renal colic in 30 (median 26 years) ...
journal_title：Archives of gynecology and obstetrics
pub_type： 杂志文章
doi：10.1007/s00404-013-2768-1
更新日期：2013-09-01 00:00:00
abstract：:Vaginoplasty using pelvic peritoneum (Rothman's method) was used in 24 patients with congenital absence of the vagina. The results are presented. Rothman (1972) described vaginoplasty using pelvic peritoneum. We have operated on 24 patients with the anomaly. In this report, the better technique for this operation and ...
journal_title：Archives of gynecology and obstetrics
pub_type： 杂志文章
doi：10.1007/BF02390702
更新日期：1991-01-01 00:00:00
abstract：PURPOSE:In spite of several policies aiming to decrease cesarean rates and related complications such as uterine rupture, data show that uterine rupture and associated morbidity are increasing along the years. Whether previously unidentified risk factors are currently playing an important role on these trends is unknow...
journal_title：Archives of gynecology and obstetrics
pub_type： 杂志文章
doi：10.1007/s00404-017-4508-4
更新日期：2017-11-01 00:00:00
