Giant oocytes in human in vitro fertilization treatments.

Abstract:

PURPOSE:Giant oocytes are potential sources of chromosomal abnormalities and should thus never be used in in vitro fertilization and embryo transfer (IVF-ET) procedures. The presence of giant oocytes may indicate the efficiency of the ovarian stimulation and can refer to the quality of sibling oocytes. METHODS:IVF cycles performed between January 2008 and November 2013 (n = 1521) were divided into two groups: Giant Oocyte Group (GO Group) contained cycles with at least one giant oocyte in the cohort of the retrieved oocytes (n = 37), Normal Group contained cycles with no giant oocytes (n = 1484). In the second part of the study, cycles from GO Group and Normal Group were matched according to patient age, number of retrieved oocytes and stimulation protocol, and thus 30 pairs were formed. Clinical and embryological data were analyzed. RESULTS:The incidence of giant oocytes was 0.3 %. The average patient age was lower (33.5 ± 3.9 vs. 35.3 ± 4.9, p = 0.02); estradiol (E2) levels (1954 ± 903 vs. 1488 ± 909 pg/l, p < 0.01) and number of retrieved oocytes (12.7 ± vs 8.1 ± 5.1, p < 0.01) were significantly higher in the GO Group. There was no difference in clinical pregnancy rates (37.8 vs. 37.4 %, p = 1.00) between the two groups. No major differences in the embryo qualities were found. In the second part of the study, fertilization rate in the matched GO Group was lower (50.6 ± 21.9 vs. 61.9 ± 22.4 %, p = 0.04). Clinical pregnancy rates (36.7 vs. 36.7 %, p = 1.00) did not differ between the matched cycles. CONCLUSIONS:Our data suggest that the stimulation protocol does not affect the incidence of giant oocytes. Giant oocytes present in cycles with higher number of retrieved oocytes in younger women. The presence of these gametes does not refer to the quality of sibling oocytes and embryos, or the outcome of the treatment.

journal_name

Arch Gynecol Obstet

authors

Lehner A,Kaszas Z,Murber A,Rigo J Jr,Urbancsek J,Fancsovits P

doi

10.1007/s00404-015-3679-0

subject

Has Abstract

pub_date

2015-09-01 00:00:00

pages

697-703

issue

3

eissn

0932-0067

issn

1432-0711

journal_volume

292

pub_type

杂志文章
  • Women's perceptions about female reproductive system: a survey from an academic obstetrics and gynecology practice.

    abstract:OBJECTIVE:To assess women's knowledge about female reproductive system and the demographic factors that may influence their perceptions. STUDY DESIGN:In this cross-sectional study, all qualifying adult women at our academic practice were asked to complete a self-administered anonymous questionnaire about the effects o...

    journal_title:Archives of gynecology and obstetrics

    pub_type: 杂志文章

    doi:10.1007/s00404-013-3116-1

    authors: Harmanli O,Ilarslan I,Kirupananthan S,Knee A,Harmanli A

    更新日期:2014-06-01 00:00:00

  • Prenatal diagnosis of the 13q-syndrome through three-dimensional ultrasonography: a case report.

    abstract:CONTEXT:The deletion of the short arm of the chromosome 13, also known as 13q syndrome, is an extremely rare chromosomal disorder. Clinical manifestations include retinoblastoma, brain anomalies, mental and growth retardation, as well as renal, cardiac, gastrointestinal, facial, lip and digital defects. Antenatal diagn...

    journal_title:Archives of gynecology and obstetrics

    pub_type: 杂志文章

    doi:10.1007/s00404-006-0128-0

    authors: Araujo Júnior E,Filho HA,Pires CR,Filho SM

    更新日期:2006-07-01 00:00:00

  • Ascites in the puerperium: a missed diagnosis of acute postpartum pancreatitis.

    abstract:INTRODUCTION:Acute pancreatitis in pregnancy is often associated with severe morbidity. It is usually an antepartum problem occurring in late pregnancy. It rarely occurs in the postpartum period and when it does diagnosis can be difficult. CASE REPORT:We report a case of 'unexplained' ascites following ventouse delive...

    journal_title:Archives of gynecology and obstetrics

    pub_type: 杂志文章

    doi:10.1007/s00404-004-0717-8

    authors: Gyang A,Kalu E,Fakokunde A,Whitlow B

    更新日期:2005-09-01 00:00:00

  • Is induced labour in the nullipara associated with more maternal and perinatal morbidity?

    abstract:PURPOSE:To ascertain any differences in foetomaternal outcomes in induced and spontaneous labour among nulliparous women delivering at term. METHODS:A retrospective matched cohort study consisting of 403 nulliparous women induced at ≥ 292 days and 806 nulliparous women with spontaneous labour at 285-291 days. RESULTS...

    journal_title:Archives of gynecology and obstetrics

    pub_type: 杂志文章

    doi:10.1007/s00404-010-1671-2

    authors: Selo-Ojeme D,Rogers C,Mohanty A,Zaidi N,Villar R,Shangaris P

    更新日期:2011-08-01 00:00:00

  • Late preterm versus term external cephalic version: an audit of a single obstetrician experience.

    abstract:PURPOSE:Recent literature evaluating the optimal timing for external cephalic version (ECV) in non-cephalic presentation is limited and hampered by methodological issues. We aimed to compare late preterm ECV [term (36-37 weeks of gestation] to term ECV ( > 37 weeks). METHODS:We conducted a retrospective cohort study o...

    journal_title:Archives of gynecology and obstetrics

    pub_type: 杂志文章

    doi:10.1007/s00404-019-05244-3

    authors: Levin G,Rottenstreich A,Weill Y,Pollack RN

    更新日期:2019-10-01 00:00:00

  • -Neonatal asphyxia as the cause of brain damage in children?-.

    abstract::The prevalence of cerebral palsy (CP) has increased over the last 15 years in most countries. This is explained by an improved survival of very low birth weight prematures. In term infants birth asphyxia is of minor significance as a cause for CP. In only 10% of all CP cases following delivery at term, birth asphyxia ...

    journal_title:Archives of gynecology and obstetrics

    pub_type: 杂志文章,评审

    doi:

    authors: Schneider H

    更新日期:1995-01-01 00:00:00

  • The propolis and boric acid can be highly suitable, alone/or as a combinatory approach on ovary ischemia-reperfusion injury.

    abstract:PURPOSE:Ovarian ischemia-reperfusion (IR) damage continues to be a serious infertility problem. The oxidative stress plays central role in the development of IR injuries. Activation of antioxidants decreases IR injuries; however, the efficacy of antioxidant agents remains controversial. Unfortunately, there has been no...

    journal_title:Archives of gynecology and obstetrics

    pub_type: 杂志文章

    doi:10.1007/s00404-019-05303-9

    authors: Geyikoglu F,Koc K,Erol HS,Colak S,Ayer H,Jama S,Eser G,Dortbudak MB,Saglam YS

    更新日期:2019-11-01 00:00:00

  • Retrospective study of outcome on vaginal and abdominal delivery in twin pregnancy in which twin 1 is presenting by the breech.

    abstract::We retrospectively reviewed the perinatal outcome of twin pregnancies cohere the first baby was presenting by the breech. 21 were delivered vaginally and 37 abdominally. Differences in perinatal outcome, as measured by Apgar score and mortality, were not apparently different. ...

    journal_title:Archives of gynecology and obstetrics

    pub_type: 杂志文章

    doi:10.1007/s004040050201

    authors: Abu-Heija AT,Ziadeh S,Abukteish F,Obeidat A

    更新日期:1998-01-01 00:00:00

  • Effect of myocardial infarction on female sexual function in women.

    abstract:PURPOSE:The aim of this study was to assess sexual function in female patients with myocardial infarction (MI). METHODS:As research instruments, an interview form of 20 questions that questioned personal characteristics was developed by researchers, Female Sexual Function Index (FSFI) that evaluated sexual dysfunction...

    journal_title:Archives of gynecology and obstetrics

    pub_type: 杂志文章

    doi:10.1007/s00404-014-3537-5

    authors: Oskay U,Can G,Camcı G

    更新日期:2015-05-01 00:00:00

  • Admission test as precursor of perinatal outcome: a prospective study.

    abstract:PURPOSE:To test the reliability of the admission test to identify the compromised fetus and thus reduce the neonatal morbidity and mortality by early intervention. METHODS:A prospective analysis over a period of 1 year from December 2007 to December 2008 included 100 antepartum patients and were evaluated for perinata...

    journal_title:Archives of gynecology and obstetrics

    pub_type: 杂志文章

    doi:10.1007/s00404-010-1406-4

    authors: Khandelwal S,Dhanaraj M,Khandelwal A

    更新日期:2010-10-01 00:00:00

  • CA 125 in the serum and tissue of patients with gynecological disease.

    abstract::Serum levels of CA 125 were determined in 239 patients suffering from gynecological malignancies. The upper limit for normal was 35 U/ml. Raised levels were found in 82% of patients with primary ovarian carcinoma, and in 29% of those with benign ovarian tumors. The values from patients with ovarian carcinomas in parti...

    journal_title:Archives of gynecology and obstetrics

    pub_type: 杂志文章

    doi:10.1007/BF00931312

    authors: Fuith LC,Daxenbichler G,Dapunt O

    更新日期:1987-01-01 00:00:00

  • The Na+/K+ co-transport system in erythrocytes from pregnant patients.

    abstract::In erythrocytes, the extrusion of a cellular sodium level load is accomplished by the Ouabain--sensitive Na+/K+ pump and by the furosemide-sensitive Na+/K(+)--cotransport, which operates against the passive sodium permeability. An abnormal low rate of net sodium extrusion by the Na+/K+ cotransport was observed in pre-...

    journal_title:Archives of gynecology and obstetrics

    pub_type: 杂志文章

    doi:10.1007/BF02766642

    authors: Heilmann L,von Tempelhoff GF,Ulrich S

    更新日期:1993-01-01 00:00:00

  • Assessment of reliability endometrial brush cytology in detection etiology of late postmenopausal bleedings.

    abstract::We evaluated the possibility of discovering bleeding causes in late postmenopausal period with cytological examination of material received by endometrial brush in comparison with Pap test and fractionated curettage. Sixty-two women in late postmenopausal period with cervical canal bleeding, treated in gynecological d...

    journal_title:Archives of gynecology and obstetrics

    pub_type: 杂志文章

    doi:10.1007/s00404-002-0414-4

    authors: Milojkovic M,Hrgovic Z,Maass N,Jonat W,Hrgovic I,Buković D,Sijanovic S

    更新日期:2004-05-01 00:00:00

  • Laparoscopic procedures during pregnancy and the risks of anesthesia: what does an obstetrician need to know?

    abstract:BACKGROUND:Nonobstetric surgery may be necessary during any stage of gestation. METHODS:The purpose of this article is to review the current recommendations (using Medline search for the relevant publications) for the perioperative anesthetic management of pregnant women undergoing laparoscopy for indications unrelate...

    journal_title:Archives of gynecology and obstetrics

    pub_type: 杂志文章,评审

    doi:10.1007/s00404-007-0338-0

    authors: Kuczkowski KM

    更新日期:2007-09-01 00:00:00

  • Modified cesarean hysterectomy technique for management of cases of placenta increta and percreta at a tertiary referral hospital in Egypt.

    abstract:PURPOSE:To evaluate the effect of a modified type II radical hysterectomy on maternal morbidities and mortality in cases with abnormally invasive placenta (AIP). METHODS:63 cases with AIP were managed at one of the largest referral centers in Egypt in a prospective study design. This technique entails devascularizatio...

    journal_title:Archives of gynecology and obstetrics

    pub_type: 杂志文章

    doi:10.1007/s00404-018-5027-7

    authors: Hussein AM,Kamel A,Raslan A,Dakhly DMR,Abdelhafeez A,Nabil M,Momtaz M

    更新日期:2019-03-01 00:00:00

  • Comparing the efficacy of intrauterine lidocaine and paracervical block in decreasing the pain associated with endometrial biopsy: a randomised trial.

    abstract:PURPOSE:Almost 50% of the patients experience moderate-to-severe pain during endometrial biopsy. The study aimed to examine the effectiveness of intrauterine lidocaine for relieving pain during endometrial biopsy. METHODS:A randomised trial was conducted in 120 patients undergoing endometrial biopsy. Sixty-seven women...

    journal_title:Archives of gynecology and obstetrics

    pub_type: 杂志文章,随机对照试验

    doi:10.1007/s00404-013-3036-0

    authors: Cengiz H,Dağdeviren H,Kaya C,Yeşil A,Çaypınar SS

    更新日期:2014-03-01 00:00:00

  • Neonatal outcome in preterm deliveries between 23 and 27 weeks' gestation with and without preterm premature rupture of membranes.

    abstract:OBJECTIVES:To characterize neonatal morbidity and mortality rates in extreme preterm deliveries (between 23 and 27 weeks' gestation) with and without PPROM, and to evaluate the association between PPROM and chorioamnionitis. METHODS:A retrospective population-based study was conducted on preterm singleton pregnancies ...

    journal_title:Archives of gynecology and obstetrics

    pub_type: 杂志文章

    doi:10.1007/s00404-008-0836-8

    authors: Newman DE,Paamoni-Keren O,Press F,Wiznitzer A,Mazor M,Sheiner E

    更新日期:2009-07-01 00:00:00

  • Inter-rater reliability and double reading analysis of an automated three-dimensional breast ultrasound system: comparison of two independent examiners.

    abstract:PURPOSE:Breast ultrasound could be a valuable tool complementary to mammography in breast cancer screening. Automated 3D breast ultrasound (ABUS) addresses challenges of hand-held ultrasound and could allow double reading analysis of ultrasound images. This trial assesses the inter-rater reliability and double reading ...

    journal_title:Archives of gynecology and obstetrics

    pub_type: 杂志文章

    doi:10.1007/s00404-017-4473-y

    authors: Maier A,Heil J,Lauer A,Harcos A,Schaefgen B,von Au A,Spratte J,Riedel F,Rauch G,Hennigs A,Domschke C,Schott S,Rom J,Schuetz F,Sohn C,Golatta M

    更新日期:2017-09-01 00:00:00

  • Periodic urinary protein creatinine ratio for predicting significant proteinuria in preeclampsia in different alternatives: time effectiveness analysis.

    abstract::Preeclampsia is a big problem in obstetrics. The diagnosis relies mainly on the detection of both hypertension and proteinuria. The gold standard for the determination of proteinuria is 24 h urinary protein creatinine ratio; however, this approach is inconvenient and it is a considerable time consuming process that mi...

    journal_title:Archives of gynecology and obstetrics

    pub_type: 信件,meta分析

    doi:10.1007/s00404-009-1167-0

    authors: Wiwanitkit V

    更新日期:2010-03-01 00:00:00

  • Serum zonulin level is not elevated in patients with polycystic ovary syndrome without metabolic syndrome.

    abstract:AIM:Polycystic ovary syndrome (PCOS) is a complex disorder with gynecological, metabolic and carcinogenic effects. Increased intestinal permeability is related with obesity, insulin resistance, type 1 and 2 diabetes mellitus. The existence of such a relationship between PCOS and intestinal permeability has come to an e...

    journal_title:Archives of gynecology and obstetrics

    pub_type: 杂志文章

    doi:10.1007/s00404-019-05345-z

    authors: Cetin Z,Kosem A,Can B,Baser O,Catak M,Turhan T,Berker D

    更新日期:2019-12-01 00:00:00

  • The use of intravenous magnesium in non-preeclamptic pregnant women: fetal/neonatal neuroprotection.

    abstract:PURPOSE:To review the effect of intravenous magnesium in obstetrics on fetal/neonatal neuroprotection. METHODS:A systematic review of published studies. RESULTS:Five randomized trials and 4 meta-analyses have shown a significant 32% reduction of cerebral palsy when administering magnesium sulfate in case of preterm d...

    journal_title:Archives of gynecology and obstetrics

    pub_type: 杂志文章,评审

    doi:10.1007/s00404-014-3581-1

    authors: Jacquemyn Y,Zecic A,Van Laere D,Roelens K

    更新日期:2015-05-01 00:00:00

  • Influence of recurrent vulvovaginal candidiasis on quality of life issues.

    abstract:PURPOSE:More than 370 million women will experience recurrent vulvovaginal candidiasis (RVVC) during their lifetime. However, RVVC is often trivialized as clinically insignificant and not worthy of research funding. We evaluated the influence of RVVC on the quality of life in affected women. METHODS:The validated Worl...

    journal_title:Archives of gynecology and obstetrics

    pub_type: 杂志文章

    doi:10.1007/s00404-019-05228-3

    authors: Fukazawa EI,Witkin SS,Robial R,Vinagre JG,Baracat EC,Linhares IM

    更新日期:2019-09-01 00:00:00

  • Uterine artery Doppler velocimetry with leiomyomas.

    abstract::The study was conducted to establish a correlation between Doppler velocimetry in relation to uterine weight in any phase of the menstrual cycle and symptoms in women who have leiomyomas. Doppler velocimetry was carried out on both uterine arteries in 18 pre-menopausal women and one post-menopausal woman prior to unde...

    journal_title:Archives of gynecology and obstetrics

    pub_type: 杂志文章

    doi:10.1007/s004040050227

    authors: Farmakides G,Stefanidis K,Paschopoulos M,Mamopoulos M,Lolis D

    更新日期:1998-01-01 00:00:00

  • Three- and four-dimensional HDlive rendering images of normal and abnormal fetuses: pictorial essay.

    abstract:BACKGROUND:Our objective is to present our experience of normal embryonic development and fetal anatomy and fetal anomalies reconstructed employing the three-dimensional (3D) and four-dimensional (4D) HDlive rendering mode. METHODS:A total of 18 normal embryos and fetuses and 21 abnormal fetuses (one case each of thor...

    journal_title:Archives of gynecology and obstetrics

    pub_type: 杂志文章

    doi:10.1007/s00404-012-2505-1

    authors: Hata T,Hanaoka U,Tenkumo C,Sato M,Tanaka H,Ishimura M

    更新日期:2012-12-01 00:00:00

  • Gynecologic oncologists' attitudes and practices relating to integrative medicine: results of a nationwide AGO survey.

    abstract:PURPOSE:The growing popularity and acceptance of integrative medicine is evident both among patients and among the oncologists treating them. As little data are available regarding health-care professionals' knowledge, attitudes, and practices relating to the topic, a nationwide online survey was designed. METHODS:Ove...

    journal_title:Archives of gynecology and obstetrics

    pub_type: 杂志文章

    doi:10.1007/s00404-017-4420-y

    authors: Klein E,Beckmann MW,Bader W,Brucker C,Dobos G,Fischer D,Hanf V,Hasenburg A,Jud SM,Kalder M,Kiechle M,Kümmel S,Müller A,Müller MT,Paepke D,Rotmann AR,Schütz F,Scharl A,Voiss P,Wallwiener M,Witt C,Hack CC

    更新日期:2017-08-01 00:00:00

  • Colon penetration by a copper intrauterine device: a case report with literature review.

    abstract:AIM:The present case report describes colon injury subsequent to uterine penetration which is associated with the use of an intrauterine device (IUD). CASE:A 29-year-old multiparous woman, who presented with vague abdominal pain, had a TCu 380A inserted at her postpartum third month visit. The T-shaped segment of the ...

    journal_title:Archives of gynecology and obstetrics

    pub_type: 杂志文章

    doi:10.1007/s00404-008-0716-2

    authors: Arslan A,Kanat-Pektas M,Yesilyurt H,Bilge U

    更新日期:2009-03-01 00:00:00

  • A population-based study of selected demographic characteristics of Israeli-Jewish women with cervical squamous cell carcinoma.

    abstract:PURPOSE:The age-standardized incidence rate (ASR) of invasive cervical cancer in Israeli-Jewish women is persistently low compared to many other countries. The aim of the present study was to assess selected demographic characteristics of Israeli-Jewish women with cervical squamous cell carcinoma (SCC) in an attempt to...

    journal_title:Archives of gynecology and obstetrics

    pub_type: 杂志文章

    doi:10.1007/s00404-010-1582-2

    authors: Menczer J,Kogan L,Schejter E,Liphshiz I,Barchana M

    更新日期:2011-03-01 00:00:00

  • Factors predicting nodal metastasis in endometrial cancer.

    abstract:PURPOSE:Evaluation of lymph node (LN) metastases in endometrial carcinoma (EC) is an important prognostic factor and a required element of cancer staging. The purpose of this study is to analyze what factors might predict the likelihood of nodal involvement in EC. METHODS:A retrospective search of our institutional da...

    journal_title:Archives of gynecology and obstetrics

    pub_type: 杂志文章

    doi:10.1007/s00404-014-3330-5

    authors: Gilani S,Anderson I,Fathallah L,Mazzara P

    更新日期:2014-12-01 00:00:00

  • Effectiveness of short-term maintenance treatment with cabergoline in microadenoma-related and idiopathic hyperprolactinemia.

    abstract:OBJECTIVE:This study aimed to determine the effectiveness of short-term maintenance treatment with cabergoline and to find out minimum effective dosage of cabergoline during maintenance treatment for patients with microadenoma-related and idiopathic hyperprolactinemia. STUDY DESIGN:Cabergoline was administered orally ...

    journal_title:Archives of gynecology and obstetrics

    pub_type: 杂志文章,随机对照试验

    doi:10.1007/s00404-010-1562-6

    authors: Buyukbayrak EE,Karageyim Karsidag AY,Kars B,Balcik O,Pirimoglu M,Unal O,Turan C

    更新日期:2010-11-01 00:00:00

  • A new look at tamoxifen: co-administration with letrozole in intrauterine insemination cycles.

    abstract:OBJECTIVE:To assess the effectiveness of tamoxifen administration with letrozole in the context of intrauterine insemination (IUI) cycles. MATERIALS AND METHODS:This prospective double-blinded study included 130 patients. After randomization, 65 patients in group A received letrozole + tamoxifen and human menopausal g...

    journal_title:Archives of gynecology and obstetrics

    pub_type: 杂志文章,随机对照试验

    doi:10.1007/s00404-012-2556-3

    authors: Pourmatroud E,Zargar M,Nikbakht R,Moramazi F

    更新日期:2013-02-01 00:00:00