Abstract:
PURPOSE:Giant oocytes are potential sources of chromosomal abnormalities and should thus never be used in in vitro fertilization and embryo transfer (IVF-ET) procedures. The presence of giant oocytes may indicate the efficiency of the ovarian stimulation and can refer to the quality of sibling oocytes. METHODS:IVF cycles performed between January 2008 and November 2013 (n = 1521) were divided into two groups: Giant Oocyte Group (GO Group) contained cycles with at least one giant oocyte in the cohort of the retrieved oocytes (n = 37), Normal Group contained cycles with no giant oocytes (n = 1484). In the second part of the study, cycles from GO Group and Normal Group were matched according to patient age, number of retrieved oocytes and stimulation protocol, and thus 30 pairs were formed. Clinical and embryological data were analyzed. RESULTS:The incidence of giant oocytes was 0.3 %. The average patient age was lower (33.5 ± 3.9 vs. 35.3 ± 4.9, p = 0.02); estradiol (E2) levels (1954 ± 903 vs. 1488 ± 909 pg/l, p < 0.01) and number of retrieved oocytes (12.7 ± vs 8.1 ± 5.1, p < 0.01) were significantly higher in the GO Group. There was no difference in clinical pregnancy rates (37.8 vs. 37.4 %, p = 1.00) between the two groups. No major differences in the embryo qualities were found. In the second part of the study, fertilization rate in the matched GO Group was lower (50.6 ± 21.9 vs. 61.9 ± 22.4 %, p = 0.04). Clinical pregnancy rates (36.7 vs. 36.7 %, p = 1.00) did not differ between the matched cycles. CONCLUSIONS:Our data suggest that the stimulation protocol does not affect the incidence of giant oocytes. Giant oocytes present in cycles with higher number of retrieved oocytes in younger women. The presence of these gametes does not refer to the quality of sibling oocytes and embryos, or the outcome of the treatment.
journal_name
Arch Gynecol Obstetjournal_title
Archives of gynecology and obstetricsauthors
Lehner A,Kaszas Z,Murber A,Rigo J Jr,Urbancsek J,Fancsovits Pdoi
10.1007/s00404-015-3679-0subject
Has Abstractpub_date
2015-09-01 00:00:00pages
697-703issue
3eissn
0932-0067issn
1432-0711journal_volume
292pub_type
杂志文章abstract:PURPOSE:To determine the presence of OC-125 staining in endometriotic lesions and to verify whether there is an association with endometriosis stage. METHODS:Thirteen patients from the Family Planning programs (group I) and 53 patients from the Chronic Pelvic Pain outpatient clinic (group II) were studied. Endometriot...
journal_title:Archives of gynecology and obstetrics
pub_type: 杂志文章
doi:10.1007/s00404-009-1055-7
更新日期:2010-01-01 00:00:00
abstract:INTRODUCTION:Polycystic ovary syndrome (PCOS) is a disorder associated with insulin resistance and obesity. Aim of our study is to clarify the prevalence of underweight in PCOS patients and whether metabolic and androgen profiles of PCOS differ depending on normal or low body weight. METHODS:Out of 1269 consecutive pa...
journal_title:Archives of gynecology and obstetrics
pub_type: 杂志文章
doi:10.1007/s00404-017-4422-9
更新日期:2017-08-01 00:00:00
abstract:PURPOSE:Color Doppler ultrasound (CDU) accuracy of kidneys and bladder in the diagnosis and treatment of hydronephrosis and/or renal colic in pregnancies was evaluated. METHODS:Between January 2010 and September 2012, 234 pregnant women asymptomatic in 204 cases and with unilateral renal colic in 30 (median 26 years) ...
journal_title:Archives of gynecology and obstetrics
pub_type: 杂志文章
doi:10.1007/s00404-013-2768-1
更新日期:2013-09-01 00:00:00
abstract::A 34 year-old female presented with blood-stained pleural effusion and ascites. Investigation revealed a pelvic mass. She underwent exploratory laparotomy, and was found to have endometriosis. Total abdominal hysterectomy and right salpingo-oophorectomy was performed. ...
journal_title:Archives of gynecology and obstetrics
pub_type: 杂志文章,评审
doi:10.1007/pl00007484
更新日期:2000-07-01 00:00:00
abstract::Interleukin-6 (IL-6) is a pleiotropic cytokine that is not only a mediator in major immunologic reactions but also a growth factor of keratinocytes. We studied the IL-6 secretion in vitro of 15 human cell lines derived from both squamous cell carcinoma (SCC) and adenocarcinoma of the uterine cervix. Four of the eight ...
journal_title:Archives of gynecology and obstetrics
pub_type: 杂志文章
doi:10.1007/BF01370929
更新日期:1996-01-01 00:00:00
abstract:OBJECTIVE:To investigate the level of cytokines and immune cells in the peripheral blood (PB) and peritoneal fluid (PF) of different stages of endometriosis. METHODS:A prospective study was conducted to include 97 women with (n 60) and without (n 37) histopathologically confirmed endometriosis. Based on rASRM classifi...
journal_title:Archives of gynecology and obstetrics
pub_type: 杂志文章
doi:10.1007/s00404-008-0844-8
更新日期:2009-06-01 00:00:00
abstract::Primary malignant tumors of the breast are the most frequently occurring neoplasms in women whereas breast metastases are rare. We report the first case, in literature, of metastasis within the breast resulting from a previous cecum carcinoma. We discuss the case and review the literature. ...
journal_title:Archives of gynecology and obstetrics
pub_type: 杂志文章,评审
doi:10.1007/s004040000158
更新日期:2001-11-01 00:00:00
abstract:OBJECTIVE:Water birth became popular in the last years, despite the fact that many questions like the risk of infection for the newborn remain unanswered. Group B streptococcal (GBS) infections in the newborn remain a challenge in obstetrics and neonatology. METHOD:We conducted a prospective trial to study the impact ...
journal_title:Archives of gynecology and obstetrics
pub_type: 杂志文章
doi:10.1007/s00404-005-0067-1
更新日期:2006-01-01 00:00:00
abstract:PURPOSE:To answer the question: are there differences in cesarean section rates among childbearing women in Canada according to selected migration indicators? METHODS:Secondary analyses of 3,500 low-risk women who had given birth between January 2003 and April 2004 in one of ten hospitals in the major Canadian migrant...
journal_title:Archives of gynecology and obstetrics
pub_type: 杂志文章
doi:10.1007/s00404-012-2609-7
更新日期:2013-04-01 00:00:00
abstract:OBJECTIVE:To evaluate the efficacy and safety of a symbol "&" compression suture technique in controlling severe atonic postpartum hemorrhage with placenta previa accreta during cesarean delivery. METHODS:Nine women with heavy postpartum bleeding from uterine inertia and placenta previa percret, which did not react to...
journal_title:Archives of gynecology and obstetrics
pub_type: 杂志文章
doi:10.1007/s00404-014-3502-3
更新日期:2015-02-01 00:00:00
abstract:PURPOSE:To evaluate intracytoplasmic sperm injection (ICSI) outcome of women over age 39 and to determine when to discourage such couples to undergo IVF using their own oocytes. METHODS:Four hundred ninety-five consecutive women (n=668 cycles) over age 39 were evaluated by year-by-year age increments to discriminate t...
journal_title:Archives of gynecology and obstetrics
pub_type: 杂志文章
doi:10.1007/s00404-009-1116-y
更新日期:2010-02-01 00:00:00
abstract:PURPOSE:Congenital HCMV infection affects about 0.5-0.9 % of newborns in Europe. Primary prevention could effectively be implemented in screening programmes for couples treated for infertility. By supplying epidemiological data, the proportion of women susceptible to primary HCMV infection is estimated. METHODS:Retros...
journal_title:Archives of gynecology and obstetrics
pub_type: 杂志文章
doi:10.1007/s00404-015-3640-2
更新日期:2015-08-01 00:00:00
abstract:PURPOSE:Low levels of plasmatic pregnancy-associated plasma protein-A (PAPP-A) and high levels of free-beta human chorionic gonadotropin (beta-hCG) could influence the outcome of pregnancy. The objective of this study is to assess the correlation between PAPP-A and free beta-hCG and birth weight. MATERIALS AND METHODS...
journal_title:Archives of gynecology and obstetrics
pub_type: 杂志文章
doi:10.1007/s00404-015-3947-z
更新日期:2016-06-01 00:00:00
abstract:PURPOSE:To compare peri-operative outcomes between laparoscopic myomectomy (LM) and laparoscopic hysterectomy (LH) for the treatment of uterine fibroids. METHODS:Retrospective cohort study including 400 women who underwent LH or LM for the management of uterine fibroids. RESULTS:LH patients were older, with higher BM...
journal_title:Archives of gynecology and obstetrics
pub_type: 杂志文章
doi:10.1007/s00404-014-3434-y
更新日期:2015-03-01 00:00:00
abstract:PURPOSE:Sonographic fetal weight (FW) estimation to detect macrosomic fetuses is an essential part of everyday routine work in obstetrics departments. Most of the commonly used weight estimation formulas underestimate FW when the actual birth weight (BW) exceeds 4000 g. One of the best-established weight estimation for...
journal_title:Archives of gynecology and obstetrics
pub_type: 杂志文章
doi:10.1007/s00404-018-4917-z
更新日期:2018-12-01 00:00:00
abstract:BACKGROUND:The Nitric Oxide (NO) system plays an important role in the establishment and maintenance of the feto-placental circulation. Research on the pathogenesis of preeclampsia in several studies has established the involvement of the NO-system in preeclampsia and fetal intrauterine growth restriction (IUGR). In th...
journal_title:Archives of gynecology and obstetrics
pub_type: 杂志文章
doi:10.1007/s00404-006-0149-8
更新日期:2006-06-01 00:00:00
abstract:PURPOSE:To compare the role of an aromatase inhibitor (letrozole) with a GnRH agonist (triptorelin) versus case control on the pregnancy rate and recurrence of symptoms and signs in patients with endometriosis. METHODS:In a prospective randomized clinical trial, after treatment of 144 infertile women in their reproduc...
journal_title:Archives of gynecology and obstetrics
pub_type: 杂志文章,随机对照试验
doi:10.1007/s00404-010-1599-6
更新日期:2011-07-01 00:00:00
abstract:INTRODUCTION:An enlarged uterus of more than 12 cm in cavum length with a distorted cavity is a contra-indication for conventional ablative techniques. It is difficult to perform satisfactory endometrial ablation in a large uterus with submucosal myomas using straight instruments. A new curved microwave applicator 4 mm...
journal_title:Archives of gynecology and obstetrics
pub_type: 杂志文章
doi:10.1007/s00404-003-0480-2
更新日期:2003-11-01 00:00:00
abstract:OBJECTIVES:To evaluate maternal and fetal outcomes among women with hyperemesis gravidarum (HG). METHODS:In a university hospital and a research and training hospital, a retrospective cohort study was conducted among women with singleton deliveries between 2003 and 2011. Maternal outcomes evaluated included gestationa...
journal_title:Archives of gynecology and obstetrics
pub_type: 杂志文章
doi:10.1007/s00404-011-2176-3
更新日期:2012-06-01 00:00:00
abstract:PURPOSE:It is suspected that delayed surgery after neoadjuvant chemotherapy (NACT) leads to a worse outcome in breast cancer patients. We therefore evaluated possible influencing factors of the time interval between the end of NACT and surgery. METHODS:All patients receiving NACT due to newly diagnosed breast cancer f...
journal_title:Archives of gynecology and obstetrics
pub_type: 杂志文章
doi:10.1007/s00404-020-05494-6
更新日期:2020-04-01 00:00:00
abstract:INTRODUCTION:A 28-year old female presented with a non-radiating persistent left upper quadrant pain and tenderness for 5 weeks. METHODS:A preliminary CT scan displayed bony structures in the spleen. A delayed scanning subsequently showed the bones to have changed position, consistent with a life fetus. RESULTS:Ultra...
journal_title:Archives of gynecology and obstetrics
pub_type: 杂志文章
doi:10.1007/s00404-007-0356-y
更新日期:2007-10-01 00:00:00
abstract:OBJECTIVE:The purpose of this study was to examine the effects of of bromocriptin combined with clomiphene citrate in clomiphene-resistant patients with polycystic ovary syndrome and normal prolactin level. DESIGN:Prospective, double-blind, controlled study. SETTING:University teaching hospital. PATIENTS:One hundred...
journal_title:Archives of gynecology and obstetrics
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1007/s00404-002-0437-x
更新日期:2004-01-01 00:00:00
abstract:AIM:Polycystic ovary syndrome (PCOS) is a complex disorder with gynecological, metabolic and carcinogenic effects. Increased intestinal permeability is related with obesity, insulin resistance, type 1 and 2 diabetes mellitus. The existence of such a relationship between PCOS and intestinal permeability has come to an e...
journal_title:Archives of gynecology and obstetrics
pub_type: 杂志文章
doi:10.1007/s00404-019-05345-z
更新日期:2019-12-01 00:00:00
abstract:BACKGROUND:Sumatriptan is an acute treatment for migraine which is often used by women in their child-bearing years, and who become unexpectedly pregnant. Within the context of the post-marketing use of sumatriptan injection for the acute treatment of migraine, and in compliance with approved labeling, we wished to com...
journal_title:Archives of gynecology and obstetrics
pub_type: 杂志文章
doi:10.1007/s004040050252
更新日期:1999-11-01 00:00:00
abstract:PURPOSE:The aim of this study was to investigate the impact of bacterial vaginal flora on life-birth rate during ICSI and influence of metronidazole as antibiotic treatment course before ICSI. METHOD:We enrolled 71 women who were undergoing ICSI. At embryo transfer (ET), all of the women had quantitative vaginal cultu...
journal_title:Archives of gynecology and obstetrics
pub_type: 杂志文章
doi:10.1007/s00404-011-1857-2
更新日期:2011-12-01 00:00:00
abstract:AIM:The aim of this study was to compare the efficacy and safety of two combination regimens in the syndromic management of lower genital infection. Seventy-two non-pregnant women presenting with symptoms of lower genital infection diagnosed as vaginitis on clinical examination and lacking obvious upper genital infecti...
journal_title:Archives of gynecology and obstetrics
pub_type: 临床试验,杂志文章
doi:10.1007/s00404-005-0071-5
更新日期:2006-01-01 00:00:00
abstract::It is rare to find osteoclastic giant cells (OGCs) as a stromal reaction in uterine adenocarcinoma of endometrium. Here, we report a case of a 60-year-old female diagnosed with adenocarcinoma of endometrium. Total hysterectomy with bilateral salpingo-oopherectomy and removal of pelvic lymphnodes was performed. Histolo...
journal_title:Archives of gynecology and obstetrics
pub_type: 杂志文章
doi:10.1007/s00404-011-2089-1
更新日期:2012-04-01 00:00:00
abstract:OBJECTIVE:To determine the association between unexplained increased nuchal translucency (INT) and adverse pregnancy outcomes. PATIENTS AND METHODS:The prospective database of our fetal down screening project was accessed to retrieve the records with NT measurement and complete follow-up. Pregnancies with pre-existing...
journal_title:Archives of gynecology and obstetrics
pub_type: 杂志文章
doi:10.1007/s00404-018-4790-9
更新日期:2018-07-01 00:00:00
abstract:PURPOSE:Stress urinary incontinence (SUI) is a major health problem that has substantial and important effects on health-related quality of life. In recent years, extracorporeal magnetic innervation (ExMI) has become a preferred method of treatment in urinary incontinence. This study presents the effects of ExMI treatm...
journal_title:Archives of gynecology and obstetrics
pub_type: 临床试验,杂志文章
doi:10.1007/s00404-010-1814-5
更新日期:2011-11-01 00:00:00
abstract:UNLABELLED:Does local injection with lidocaine plus epinephrine prior to vaginal reconstructive surgery with synthetic mesh affect exposure rates? A retrospective comparison. PURPOSE:To determine if local injection, prior to incision with lidocaine plus epinephrine (L + E) influences the rate of mesh exposure in the e...
journal_title:Archives of gynecology and obstetrics
pub_type: 杂志文章
doi:10.1007/s00404-010-1715-7
更新日期:2011-09-01 00:00:00