Hyaluronan binding assay does not predict pregnancy rates in IUI cycles in couples with unexplained infertility.

Abstract:

PURPOSE:To investigate the relationship between hyaluronan binding (HB) assay and pregnancy rates in intrauterine insemination (IUI) cycles. METHODS:This prospective cohort study was done in Hacettepe University, a tertiary care center for reproductive medicine. Seventy-one consecutive couples who suffered from unexplained infertility and underwent controlled ovarian hyperstimulation (COH) and IUI were enrolled into the study. RESULTS:From the 71 IUI patients, the clinical pregnancy rate was 14.1% (10 of 71). HB ratio from the overall patient number was 48.6±25.9. The mean HB ratio in pregnant and non-pregnant groups was comparable (50.2±25.2 vs. 48.3±26.2, respectively, p>0.05). CONCLUSIONS:Hyaluronan binding assay does not predict pregnancy rates in IUI cycles in couples with unexplained infertility.

journal_name

Arch Gynecol Obstet

authors

Boynukalin FK,Esinler I,Guven S,Gunalp S

doi

10.1007/s00404-012-2476-2

subject

Has Abstract

pub_date

2012-12-01 00:00:00

pages

1577-80

issue

6

eissn

0932-0067

issn

1432-0711

journal_volume

286

pub_type

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