Abstract：
PURPOSE:To assess the efficacy and safety of an intravenous formulation of tranexamic acid to reduce intrapartum and postpartum bleeding in patients giving birth by cesarean section. METHODS:Healthy women with normal pregnancies, at any gestational age, that we performed ceaserean section. Two hundred and twenty-three patients with cesarean section, were enrolled in a double-blind, placebo-controlled study. Tranexamic acid of 20 cc and a 20 cc 5 % dextrose solution was intravenously injected to the patients; both the study group (n = 101) and the control group (n = 122) 10 min before the start of cesarean section. We measured volume of blood loss in postoperative periods, decrease in hemoglobin and hematocrit levels after cesarean section. The mean follow up was 2 weeks after the operation. RESULTS:Tranexamic acid reduced intraoperative and postoperative blood loss. We did not observe any complications caused by TA such as venous thromboembolism, gastrointestinal problems and hypersensitivity. CONCLUSIONS:This study confirms that tranexamic acid is effective in reducing intrapartum and postpartum bleeding in patients giving birth by cesarean section. Although some obstetricians are still worried about its thrombosis risk, our study shows that it can be used safely in aforementioned patients.
journal_name
Arch Gynecol Obstetjournal_title
Archives of gynecology and obstetricsauthors
Sentürk MB,Cakmak Y,Yildiz G,Yildiz Pdoi
10.1007/s00404-012-2624-8subject
Has Abstractpub_date
2013-04-01 00:00:00pages
641-5issue
4eissn
0932-0067issn
1432-0711journal_volume
287pub_type
杂志文章,随机对照试验abstract：OBJECTIVE:To compare the efficacy and safety of fentanyl iontophoretic transdermal system (ITS) with morphine intravenous patient-controlled analgesia (IV PCA) for pain management following gynecologic surgery. METHOD:A subgroup (n = 275) of gynecologic surgery patients from a randomized study (N = 636) of patients tr...
journal_title：Archives of gynecology and obstetrics
pub_type： 杂志文章,多中心研究,随机对照试验
doi：10.1007/s00404-007-0339-z
更新日期：2007-09-01 00:00:00
abstract：PURPOSE:To ascertain any differences in foetomaternal outcomes in induced and spontaneous labour among nulliparous women delivering at term. METHODS:A retrospective matched cohort study consisting of 403 nulliparous women induced at ≥ 292 days and 806 nulliparous women with spontaneous labour at 285-291 days. RESULTS...
journal_title：Archives of gynecology and obstetrics
pub_type： 杂志文章
doi：10.1007/s00404-010-1671-2
更新日期：2011-08-01 00:00:00
abstract：PURPOSE:To study the relation of pelvic pain symptoms and pelvic adhesions to Doppler ultrasound findings in patients with ovarian endometriomas. METHODS:62 patients who underwent laparoscopic surgery for endometrioma were divided into two groups according to their pelvic pain symptoms. Group 1 (n = 27) included patie...
journal_title：Archives of gynecology and obstetrics
pub_type： 杂志文章
doi：10.1007/s00404-012-2630-x
更新日期：2013-04-01 00:00:00
abstract：:Interleukin-6 (IL-6) is a pleiotropic cytokine that is not only a mediator in major immunologic reactions but also a growth factor of keratinocytes. We studied the IL-6 secretion in vitro of 15 human cell lines derived from both squamous cell carcinoma (SCC) and adenocarcinoma of the uterine cervix. Four of the eight ...
journal_title：Archives of gynecology and obstetrics
pub_type： 杂志文章
doi：10.1007/BF01370929
更新日期：1996-01-01 00:00:00
abstract：INTRODUCTION:Morbid obesity is perhaps the most common nutritional disorder seen in pregnancy, and morbidly obese parturients have more pregnancy complication than normal body mass index (BMI) pregnant patients. Combined spinal epidural anesthesia (CSEA) has become a well-established alternative to epidural analgesia f...
journal_title：Archives of gynecology and obstetrics
pub_type： 杂志文章
doi：10.1007/s00404-004-0634-x
更新日期：2005-04-01 00:00:00
abstract：PURPOSE:Prematurity is the most common cause of infant mortality and morbidity. To prevent this, the timing of parturition and its mechanisms should be understood. It is likely that inhibitor CD94/NKG2A positive decidual natural killer cells (uNK) provide for the continuation of pregnancy. Here, we aimed to evaluate wh...
journal_title：Archives of gynecology and obstetrics
pub_type： 杂志文章
doi：10.1007/s00404-015-3978-5
更新日期：2016-08-01 00:00:00
abstract：BACKGROUND:The management of ovarian cancer during pregnancy represents a major challenge and requires close multidisciplinary team approach. CASE:A 35-year-old pregnant woman with a yolk sac tumor underwent left salpingo-oophorectomy at 25 weeks of gestation. Chemotherapy was deferred to the end of the pregnancy owin...
journal_title：Archives of gynecology and obstetrics
pub_type： 杂志文章
doi：10.1007/s00404-009-0977-4
更新日期：2009-11-01 00:00:00
abstract：OBJECTIVE:Polycystic ovary syndrome (PCOS) is the most common endocrine disorder in reproductive age women. The clinical symptoms of PCOS vary with female age, as older women tend to have lower hyperandrogenic symptoms and many regain regular cycles. In this study, we aimed to estimate the prevalence of PCOS among olde...
journal_title：Archives of gynecology and obstetrics
pub_type： 杂志文章
doi：10.1007/s00404-017-4642-z
更新日期：2018-04-01 00:00:00
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journal_title：Archives of gynecology and obstetrics
pub_type： 杂志文章
doi：10.1007/s00404-013-2958-x
更新日期：2014-02-01 00:00:00
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journal_title：Archives of gynecology and obstetrics
pub_type： 杂志文章
doi：10.1007/s00404-002-0453-x
更新日期：2004-09-01 00:00:00
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journal_title：Archives of gynecology and obstetrics
pub_type： 杂志文章
doi：10.1007/s00404-014-3508-x
更新日期：2015-05-01 00:00:00
abstract：PURPOSE:In spite of several policies aiming to decrease cesarean rates and related complications such as uterine rupture, data show that uterine rupture and associated morbidity are increasing along the years. Whether previously unidentified risk factors are currently playing an important role on these trends is unknow...
journal_title：Archives of gynecology and obstetrics
pub_type： 杂志文章
doi：10.1007/s00404-017-4508-4
更新日期：2017-11-01 00:00:00
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journal_title：Archives of gynecology and obstetrics
pub_type： 杂志文章
doi：10.1007/s00404-008-0746-9
更新日期：2009-04-01 00:00:00
abstract：PURPOSE:The aim of this study was to evaluate the relationship between serum beta-human chorionic gonadotropin (β-hCG) and preeclampsia (PE) and the effects of βhCG on maternal and perinatal outcomes. METHODS:This case-control study included 125 pregnant women who were admitted to the labor ward of the Maternity Teach...
journal_title：Archives of gynecology and obstetrics
pub_type： 杂志文章
doi：10.1007/s00404-019-05041-y
更新日期：2019-03-01 00:00:00
abstract：OBJECTIVE:To identify differentially expressed genes (DEGs) in endometriosis and further analyze molecular mechanisms implicated in disease pathogenesis. MATERIALS AND METHODS:Gene expression data (ID: GSE7846) of human endometrial endothelial cells (HEECs) collected from eutopic endometria tissue of patients with and...
journal_title：Archives of gynecology and obstetrics
pub_type： 杂志文章
doi：10.1007/s00404-015-3875-y
更新日期：2016-04-01 00:00:00
abstract：:A thirty four year old woman with recurrent catamenial pneumothorax is described. Pleural endometriosis was suspected and cytologic examination of fluid drained from the right pleural cavity showed glandular cell clusters of probable endometrial origin. The patient received a long-acting GnRH agonist (Triptorelin-Arve...
journal_title：Archives of gynecology and obstetrics
pub_type： 杂志文章
doi：10.1007/BF01314646
更新日期：1995-01-01 00:00:00
abstract：PURPOSE:To assess changing trends, role of the triad patient-pregnancy-health professionals and health care cost in emergency peripartum hysterectomy (EPH). METHODS:Demographics, indications, perinatal outcomes, perioperative complications in EPH cases performed in a 10-year period were extracted from the local birth ...
journal_title：Archives of gynecology and obstetrics
pub_type： 杂志文章
doi：10.1007/s00404-020-05504-7
更新日期：2020-05-01 00:00:00
abstract：PURPOSE:To compare the effectiveness of intravenous carbetocin to that of intravenous oxytocin for prevention of atonic postpartum hemorrhage (PPH) after vaginal delivery in high-risk singleton pregnancies. METHODS:This triple-blind randomized controlled trial included singleton pregnant women who delivered at Siriraj...
journal_title：Archives of gynecology and obstetrics
pub_type： 杂志文章,随机对照试验
doi：10.1007/s00404-018-4806-5
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journal_title：Archives of gynecology and obstetrics
pub_type： 杂志文章
doi：10.1007/s00404-013-2746-7
更新日期：2013-08-01 00:00:00
abstract：:For clinical purposes, diagnostic added value of HE4 is important. Diagnostic knowledge is not provided by answering the question, "How accurate is this test?" (test accuracy research). Diagnostic knowledge is the information needed to answer the question, "What is the probability of the presence or absence of a speci...
journal_title：Archives of gynecology and obstetrics
pub_type： 评论,信件
doi：10.1007/s00404-020-05681-5
更新日期：2020-10-01 00:00:00
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journal_title：Archives of gynecology and obstetrics
pub_type： 杂志文章,meta分析
doi：10.1007/s00404-015-3721-2
更新日期：2015-10-01 00:00:00
abstract：PURPOSE:Adenomyosis has been studied throughout the years, however, its aetiology and physiopathology are still unknown. The aim of this study was to identify the presence of PIWI proteins in women with adenomyosis. METHODS:We included 72 participants to be part of this study and were divided into two groups based on ...
journal_title：Archives of gynecology and obstetrics
pub_type： 杂志文章
doi：10.1007/s00404-020-05660-w
更新日期：2020-10-01 00:00:00
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journal_title：Archives of gynecology and obstetrics
pub_type： 临床试验,杂志文章,随机对照试验
doi：10.1007/s00404-003-0513-x
更新日期：2004-09-01 00:00:00
abstract：OBJECTIVE:To evaluate the accuracy of integrated FDG-PET/CT and tumor markers for the depiction of recurrent ovarian carcinoma. METHODS:Patients with pathologically proven ovarian cancer, who underwent cytoreductive surgery and 3-6 cycles of adjuvant chemotherapy, were included in this study. They all underwent a thor...
journal_title：Archives of gynecology and obstetrics
pub_type： 杂志文章
doi：10.1007/s00404-010-1404-6
更新日期：2011-02-01 00:00:00
abstract：OBJECTIVES:Cervical cancer is the most common malignant tumor in female reproductive tract and primarily metastasizes through the lymphatic system that will affect prognosis of patients. Maspin, a member of the serine protease inhibitors (serpins) super family, has recently been indicated as a tumor suppressor in many ...
journal_title：Archives of gynecology and obstetrics
pub_type： 杂志文章
doi：10.1007/s00404-013-2988-4
更新日期：2014-02-01 00:00:00
abstract：BACKGROUND:Desmoid tumors are benign neoplasms that most often arise from muscle aponeurosis and have been associated with both trauma and pregnancy. The etiology of desmoids has not been determined. CLINICAL CHARACTERISTICS:We present here four almost identical cases with desmoids occurring in the same location, the ...
journal_title：Archives of gynecology and obstetrics
pub_type： 杂志文章
doi：10.1007/s00404-008-0830-1
更新日期：2009-06-01 00:00:00
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journal_title：Archives of gynecology and obstetrics
pub_type： 杂志文章,评审
doi：10.1007/s00404-007-0338-0
更新日期：2007-09-01 00:00:00
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journal_title：Archives of gynecology and obstetrics
pub_type： 杂志文章,meta分析
doi：10.1007/s00404-017-4643-y
更新日期：2018-03-01 00:00:00
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journal_title：Archives of gynecology and obstetrics
pub_type： 杂志文章
doi：10.1007/s00404-014-3254-0
更新日期：2014-10-01 00:00:00
abstract：PURPOSE:The incidence of ectopic pregnancy (EP) in the general population is 2%, whereas the EP rate following assisted reproductive technologies (ART) is between 2.1 and 11%. EP is also an adverse effect of tubal surgery with incidences up to 40% depending on the type, location, and severity of tubal disease and the s...
journal_title：Archives of gynecology and obstetrics
pub_type： 杂志文章
doi：10.1007/s00404-011-2092-6
更新日期：2012-03-01 00:00:00
