Abstract:
:For clinical purposes, diagnostic added value of HE4 is important. Diagnostic knowledge is not provided by answering the question, "How accurate is this test?" (test accuracy research). Diagnostic knowledge is the information needed to answer the question, "What is the probability of the presence or absence of a specific disease given these test results?" (diagnostic accuracy research). Therefore, diagnostic added value of HE4 expression (differences of ROC curves for two diagnostic models with and without HE4) is important in clinical practice. Without assessing reliability, we cannot judge about diagnostic value. The diagnostic value is estimated by two parameters: reliability and accuracy.
journal_name
Arch Gynecol Obstetjournal_title
Archives of gynecology and obstetricsauthors
Sabour Sdoi
10.1007/s00404-020-05681-5subject
Has Abstractpub_date
2020-10-01 00:00:00pages
1041-1042issue
4eissn
0932-0067issn
1432-0711pii
10.1007/s00404-020-05681-5journal_volume
302pub_type
评论,信件abstract::The aim of the present study was to evaluate the effect of age and human papillomavirus (HPV) infection associated cellular changes on the predictive value of cervical cytology. In a group of 671 women with Papanicolaou smears suggesting low grade squamous intraepithelial lesion (LSIL), a high grade squamous intraepit...
journal_title:Archives of gynecology and obstetrics
pub_type: 杂志文章
doi:10.1007/BF00634344
更新日期:1995-01-01 00:00:00
abstract:PURPOSE:Features of polycystic ovarian syndrome (PCOS) including sonographic aspects, androgens, LH and LH/FSH ratio as well as Anti-Mullerian Hormone (AMH) were evaluated according to their diagnostic potency in detecting different degrees of PCOS severity. METHODS:80 women with PCOS diagnosed according to the Rotter...
journal_title:Archives of gynecology and obstetrics
pub_type: 杂志文章
doi:10.1007/s00404-014-3317-2
更新日期:2014-11-01 00:00:00
abstract::Three new progestins with a high gestagenic potency have been developed as derivatives of the levonorgestrel (in brackets: biological active substance in the human): desogestrel (3-keto-desogestrel), norgestimate (norgestimate), gestodene (gestodene). In combination with low dosages of ethinylestradiol (30-35 microgra...
journal_title:Archives of gynecology and obstetrics
pub_type: 杂志文章,评审
doi:10.1007/BF02417654
更新日期:1989-01-01 00:00:00
abstract:PURPOSE:To correlate preoperative ultrasound examination with intraoperative and anatomo-pathological findings, including estimation of number, localization and size of uterine myomas, uterine diameters and volume. METHODS:A prospective study on 126 women undergoing surgery for uterine myomatosis at Campus Bio-medico ...
journal_title:Archives of gynecology and obstetrics
pub_type: 杂志文章
doi:10.1007/s00404-015-3937-1
更新日期:2016-06-01 00:00:00
abstract::Premature ovarian insufficiency (POI) is defined as the cessation of ovarian function under the age of 40 years and is characterized by amenorrhea, hypoestrogenism, and elevated serum gonadotrophin concentration (FSH). It is a heterogeneous disorder with a multicausal pathogenesis; however, majority of cases are idiop...
journal_title:Archives of gynecology and obstetrics
pub_type: 杂志文章
doi:10.1007/s00404-010-1623-x
更新日期:2010-12-01 00:00:00
abstract::Vitamin E, a potent antioxidant, may play a role in preventing preeclampsia. Maternal blood samples were collected between 28 and 40 weeks' gestation from women with mild preeclampsia (n=17), women with severe preeclampsia (n=16) and the control group (n=15). This control group was consisted of 15 pregnant women witho...
journal_title:Archives of gynecology and obstetrics
pub_type: 杂志文章
doi:10.1007/s004040050271
更新日期:2000-04-01 00:00:00
abstract::Breast cancer is the most common malignancy in women with increasing incidence. The occurrence of metastatic disease to the breast in both females and males is relatively rare, constituting 0.5-6% of all breast malignancies. The therapy of secondary breast cancer is usually completely different from that of primary ma...
journal_title:Archives of gynecology and obstetrics
pub_type: 杂志文章,评审
doi:10.1007/s00404-011-1904-z
更新日期:2011-09-01 00:00:00
abstract:BACKGROUND:Type-II endometrial cancer is an estrogen independent and one of the most lethal types of cancer having poor prognosis. Adipokines play a crucial role in the triggering Type-II EMC. In addition, adipokines modulators, therefore, may have beneficial effects in the treatment of Type-II endometrial cancer, whic...
journal_title:Archives of gynecology and obstetrics
pub_type: 杂志文章,评审
doi:10.1007/s00404-019-05181-1
更新日期:2019-08-01 00:00:00
abstract:BACKGROUND:Membranous dysmenorrhea is a rare entity involving expulsion of fragments of endometrium retaining the shape of the uterus. The condition is often linked to high progesterone levels. An association with a chronic fatigue syndrome was never described. CASE:A 44-year-old woman with a chronic fatigue syndrome ...
journal_title:Archives of gynecology and obstetrics
pub_type: 杂志文章,评审
doi:10.1007/s00404-008-0795-0
更新日期:2009-05-01 00:00:00
abstract:PURPOSE:Complementary medicine services are nowadays usually quite heterogeneous, and little information is available on standards for running an integrative medicine consultancy service. This study aimed to assess patients' satisfaction with a standardized treatment service on integrative medicine. METHODS:Using a cr...
journal_title:Archives of gynecology and obstetrics
pub_type: 杂志文章
doi:10.1007/s00404-018-4779-4
更新日期:2018-07-01 00:00:00
abstract::We report a case of repeated fetal death at 31 gestational weeks associated with mild non-proteinuric pre-eclampsia and intrauterine growth retardation. After double intradermal immunisation with paternal leukocytes, a third pregnancy proceeded uneventfully until it ended at 38 weeks. Maternal anti-paternal blocking a...
journal_title:Archives of gynecology and obstetrics
pub_type: 杂志文章
doi:10.1007/BF02389636
更新日期:1992-01-01 00:00:00
abstract:BACKGROUND:Internal herniation of small intestine in the lesser pelvis alongside iliac vasculature is a rare occurrence. Skeletonization of iliac vessels during pelvic lymph node dissection (LND), as part of surgical staging or treatment of patients with uterine, ovarian or urogenital cancer, is a strict prerequisite f...
journal_title:Archives of gynecology and obstetrics
pub_type: 杂志文章,评审
doi:10.1007/s00404-020-05724-x
更新日期:2020-11-01 00:00:00
abstract:PURPOSE:To investigate the efficacy of wide local excision as a surgical treatment for early-stage vulvar melanomas. METHODS:Wide local excision with or without lymph node dissection was performed in three patients with stage I vulvar melanoma (American Joint Committee on Cancer classification, 1992). RESULTS:All thr...
journal_title:Archives of gynecology and obstetrics
pub_type: 杂志文章
doi:10.1007/s00404-009-1134-9
更新日期:2010-02-01 00:00:00
abstract::Ultrasonic findings in 1317 operatively confirmed gynecological tumors were classified according to five degrees of homogeneity: I, clearly outlined solitary cysts; II, clearly outlined homogeneous tumors; III, poorly defined or slightly heterogeneous tumors; IV, marked heterogeneous tumors; V, completely heterogeneou...
journal_title:Archives of gynecology and obstetrics
pub_type: 杂志文章
doi:10.1007/BF02417449
更新日期:1989-01-01 00:00:00
abstract:OBJECTIVE:Effective cytotoxic treatment options for advanced cervical cancer are exceedingly limited. Therefore, interest has increased in targeted therapeutics for the treatment of cervical cancer. Cetuximab, a monoclonal antibody, binds specifically to the epidermal growth factor receptor (EGFR) and competitively inh...
journal_title:Archives of gynecology and obstetrics
pub_type: 杂志文章
doi:10.1007/s00404-010-1389-1
更新日期:2011-01-01 00:00:00
abstract::We retrospectively reviewed the perinatal outcome of twin pregnancies cohere the first baby was presenting by the breech. 21 were delivered vaginally and 37 abdominally. Differences in perinatal outcome, as measured by Apgar score and mortality, were not apparently different. ...
journal_title:Archives of gynecology and obstetrics
pub_type: 杂志文章
doi:10.1007/s004040050201
更新日期:1998-01-01 00:00:00
abstract:BACKGROUND:Transversus abdominis plane (TAP) block has been shown to provide pain relief after abdominal procedures. However, TAP block combined with multimodal analgesia technique have not been assessed in a randomized controlled trial. This randomized, controlled, observer-blinded study was designed to evaluate the a...
journal_title:Archives of gynecology and obstetrics
pub_type: 杂志文章,随机对照试验
doi:10.1007/s00404-012-2698-3
更新日期:2013-07-01 00:00:00
abstract::Diet may act as a cofactor in the development of cancer of the cervix. A consistent correlation exists between low tissue concentrations, low serum level, and low intake of vitamin A, beta-carotene, vitamin C, or folic acid and an increased prevalence of cervical neoplasia. A moderate effect is seen in clinical trials...
journal_title:Archives of gynecology and obstetrics
pub_type: 杂志文章,评审
doi:10.1007/BF00933072
更新日期:1989-01-01 00:00:00
abstract:PURPOSE:To determine the presence of OC-125 staining in endometriotic lesions and to verify whether there is an association with endometriosis stage. METHODS:Thirteen patients from the Family Planning programs (group I) and 53 patients from the Chronic Pelvic Pain outpatient clinic (group II) were studied. Endometriot...
journal_title:Archives of gynecology and obstetrics
pub_type: 杂志文章
doi:10.1007/s00404-009-1055-7
更新日期:2010-01-01 00:00:00
abstract:AIM:To evaluate postoperative sexual functioning and the influence of patients' expectations on the change in sexuality following laparoscopic total (TLH) versus subtotal hysterectomy (LASH). METHODS:A total of 120 women undergoing laparoscopic hysterectomy were preoperatively enrolled in this bicentric prospective st...
journal_title:Archives of gynecology and obstetrics
pub_type: 杂志文章
doi:10.1007/s00404-018-4812-7
更新日期:2018-08-01 00:00:00
abstract:PURPOSE:The occurrence of diminished ovarian reserve (DOR) in women was growing in recent years. Although in vitro fertilization and embryo transfer (IVF-ET) became an effective treatment for DOR, the live-birth (LB) rate remains unsatisfactory. This study aimed to investigate the impact factors of LB rate in women wit...
journal_title:Archives of gynecology and obstetrics
pub_type: 杂志文章
doi:10.1007/s00404-018-4884-4
更新日期:2018-11-01 00:00:00
abstract::It is hoped that if cases of vulvar pilonidal sinus (PS) are known to readers of this article, they will be called to the writer's attention and that further studies of the origin and cause of these anterior pathologic developments will result. A delay in diagnosis and treatment of this relatively harmless condition c...
journal_title:Archives of gynecology and obstetrics
pub_type: 杂志文章
doi:10.1007/s00404-008-0612-9
更新日期:2008-11-01 00:00:00
abstract:PURPOSE:Decreased oocyte maturation rate (OMR) is associated with worse clinical outcomes in IVF/ICSI cycles. The clinical features inducing decreased OMR remain unknown. The study is designed to explore the factors influencing the incidence of decreased OMR and its effects on clinical outcomes. METHODS:This is a retr...
journal_title:Archives of gynecology and obstetrics
pub_type: 杂志文章
doi:10.1007/s00404-018-4958-3
更新日期:2019-02-01 00:00:00
abstract::In erythrocytes, the extrusion of a cellular sodium level load is accomplished by the Ouabain--sensitive Na+/K+ pump and by the furosemide-sensitive Na+/K(+)--cotransport, which operates against the passive sodium permeability. An abnormal low rate of net sodium extrusion by the Na+/K+ cotransport was observed in pre-...
journal_title:Archives of gynecology and obstetrics
pub_type: 杂志文章
doi:10.1007/BF02766642
更新日期:1993-01-01 00:00:00
abstract:PURPOSE:Congenital HCMV infection affects about 0.5-0.9 % of newborns in Europe. Primary prevention could effectively be implemented in screening programmes for couples treated for infertility. By supplying epidemiological data, the proportion of women susceptible to primary HCMV infection is estimated. METHODS:Retros...
journal_title:Archives of gynecology and obstetrics
pub_type: 杂志文章
doi:10.1007/s00404-015-3640-2
更新日期:2015-08-01 00:00:00
abstract:PURPOSE:Inflammatory mediators, including chemokines, may play crucial roles in the development of endometriosis. Therefore, we investigated the expression and localization of CXCL16 and its receptor, CXCR6, in ovarian endometriotic tissues. We also examined whether CXCL16 induces IL-8 production in endometriotic strom...
journal_title:Archives of gynecology and obstetrics
pub_type: 杂志文章
doi:10.1007/s00404-011-2002-y
更新日期:2011-12-01 00:00:00
abstract:PURPOSE:To determine whether quadrivalent HPV vaccination is effective in reducing recurrent disease in women with a previous history of HPV disease. METHODS:All women under 45 years of age treated for HPV-linked disease and with negative HPV test, cytology and colposcopy 3 months after treatment were enrolled. Women ...
journal_title:Archives of gynecology and obstetrics
pub_type: 杂志文章,随机对照试验
doi:10.1007/s00404-018-4926-y
更新日期:2018-12-01 00:00:00
abstract:PURPOSE:To identify whether CGRP and PTHrP serve as screening biomarkers for early detection of preeclampsia or even before the development of preeclampsia in early pregnancy. METHODS:It was a nested case-control study. The subjects were divided into normotensive (controls) and preeclamptic (cases) groups. Serum sampl...
journal_title:Archives of gynecology and obstetrics
pub_type: 杂志文章
doi:10.1007/s00404-014-3303-8
更新日期:2014-11-01 00:00:00
abstract:BACKGROUND:Meig's and Pseudo-Meig's syndromes have been reported in association with several malignancies but the concomitant existence of multiple synchronous benign and malignant tumors in association with Pseudo-Meigs' syndrome has not been reported in the published literature. CASE:A 55-year old African American w...
journal_title:Archives of gynecology and obstetrics
pub_type: 杂志文章
doi:10.1007/s00404-005-0052-8
更新日期:2006-02-01 00:00:00
abstract:PURPOSE:To identify risk factors for the development of severe perineal lacerations and to give recommendations for their prevention in nulliparous women. METHODS:A retrospective case-control analysis of deliveries at our University Hospital was performed. Multiparae, Caesarean sections, twin pregnancies, fetal breech...
journal_title:Archives of gynecology and obstetrics
pub_type: 杂志文章
doi:10.1007/s00404-009-1063-7
更新日期:2010-01-01 00:00:00