Abstract:
PURPOSE:Surgical management of posterior vaginal wall prolapse has variable functional outcomes. Synthetic and biological grafts are used to improve outcomes and reduce failures. The objective of this study was to determine the functional outcomes and its implications on patient-reported quality of life of a technique of posterior vaginal wall repair and prespinous colpopexy with biological small intestinal submucosal (SIS) graft in the management of posterior vaginal wall prolapse. METHODS:This prospective cohort study was conducted in a urogynaecology subspecialty center in the UK. Women with moderate degree rectocele or more, with or without other compartmental prolapse underwent posterior vaginal wall repair and prespinous colpopexy with SIS graft over a 3-year period. ICIQ vaginal symptoms questionnaires were used pre-operatively and at 6 months post-operatively to assess functional outcomes. The Wilcoxon signed R test was used to analyze the results. RESULTS:50 women underwent posterior repair with SIS graft (27 with concomitant procedures). There was a statistically significant improvement (p < 0.0001) in the vaginal symptoms and sexual matters scores at 6-month follow-up in all the women. The quality of life scores also improved significantly (p < 0.0001) in all the women. Concomitant pelvic surgery did not affect the outcomes (p < 0.0001). There were no significant intra- or post-operative complications. CONCLUSION:Posterior vaginal wall repair and prespinous colpopexy with biological SIS graft is an effective surgical option for managing women with posterior vaginal wall prolapse with or without other concomitant compartmental defects.
journal_name
Arch Gynecol Obstetjournal_title
Archives of gynecology and obstetricsauthors
Madhu C,Cooke J,Harber P,Holmes Ddoi
10.1007/s00404-014-3254-0subject
Has Abstractpub_date
2014-10-01 00:00:00pages
711-6issue
4eissn
0932-0067issn
1432-0711journal_volume
290pub_type
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journal_title:Archives of gynecology and obstetrics
pub_type: 杂志文章,多中心研究
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abstract::When counselling an HIV-seropositive pregnant woman, one must consider both the fate of the mother in relation to pregnancy-induced effects on the HIV infection and the development rate of the transplacental infection to the child. The difficulties in correctly diagnosing HIV infection in the newborn are discussed; it...
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pub_type: 杂志文章,随机对照试验
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更新日期:2019-12-01 00:00:00