Abstract：
PURPOSE:Τo estimate the discrepancy rate between colposcopy, punch biopsy histology and surgical specimen histology as well as the positive (PPV) and negative predictive value (NPV) of colposcopic diagnosis for high-grade squamous intraepithelial lesions (HGSIL). METHODS:A prospective study was conducted during the period of 2012-2016. Αll cases in which surgical treatment had been applied and histopathological diagnosis of those surgical specimens was available were included. Cases in which ablation was performed and cases with incomplete data or conservative approach were excluded. Primary outcome was the agreement rate between histologic diagnosis of surgical specimen, histologic diagnosis of punch biopsy and colposcopic diagnosis according to REID Colposcopic Index. PPV and NPV of colposcopy and biopsy to diagnose HGSIL were also assessed. RESULTS:Τhere were 120 cases meeting our inclusion criteria, while biopsy was obtained in 104 cases. Mean age of women was 32.7 ± 9.0. Colposcopic diagnosis was CIN2 in 65 cases, CIN3 in 11 cases, CIN1 or less in 44 cases. Τhe level of agreement was fair between colposcopy-surgical specimen histology (κ value 0.443), fair between colposcopy-punch biopsy (κ value 0.34) and moderate between punch biopsy-cone specimen histology (κ value 0.443). PPV of colposcopy to detect HGSIL was 72.3%, while NPV was only 47.7%. CONCLUSION:Punch biopsy and surgical specimen histology present the highest agreement between the different diagnostic procedures. Colposcopy presented satisfying PPV for HGSIL cases, but its NPV was poor. In contrary, punch biopsy was characterized by both satisfying PPV and NPV for HGSIL cases.
journal_name
Arch Gynecol Obstetjournal_title
Archives of gynecology and obstetricsauthors
Petousis S,Christidis P,Margioula-Siarkou C,Sparangis N,Athanasiadis A,Kalogiannidis Idoi
10.1007/s00404-018-4714-8subject
Has Abstractpub_date
2018-05-01 00:00:00pages
1271-1275issue
5eissn
0932-0067issn
1432-0711pii
10.1007/s00404-018-4714-8journal_volume
297pub_type
杂志文章abstract：INTRODUCTION:The high incidence of multiple pregnancies is a major concern in the treatment of infertility by in vitro fertilization (IVF). Risks and costs are associated with multiple pregnancies and it is important to find a way to decrease multiple pregnancies. The standard protocol for IVF includes the transfer of ...
journal_title：Archives of gynecology and obstetrics
pub_type： 临床试验,杂志文章,随机对照试验
doi：10.1007/s00404-003-0513-x
更新日期：2004-09-01 00:00:00
abstract：PURPOSE:There is literature suggesting an intergenerational relationship between maternal and infant size for gestational age status and preterm birth, but much less is known about the contribution of paternal birth outcome to infant birth outcome. This study seeks to determine the association between paternal and infa...
journal_title：Archives of gynecology and obstetrics
pub_type： 杂志文章
doi：10.1007/s00404-020-05712-1
更新日期：2020-11-01 00:00:00
abstract：:For the elucidation of hypothalamic factors, which predominantly cause exercise-amenorrhea 10 untrained and 6 trained volunteers were experimentally tested during 6 hours of rest (R) and 2 hours long distance run (E). The exercise exerted several physical and metabolic demands, leading to increment of LH pulse frequen...
journal_title：Archives of gynecology and obstetrics
pub_type： 杂志文章
doi：10.1007/BF02417672
更新日期：1989-01-01 00:00:00
abstract：PURPOSE:In our study, we try to investigate whether magnesium sulphate (MgSO4) could provide protection against oxidative damage and inflammatory response in rat placenta of intrahepatic cholestasis of pregnancy (ICP) model. METHODS:The rat model of ICP was established by injecting s.c. 17α-ethinyl estradiol (EE) dail...
journal_title：Archives of gynecology and obstetrics
pub_type： 杂志文章
doi：10.1007/s00404-018-4850-1
更新日期：2018-09-01 00:00:00
abstract：PURPOSE:Preeclampsia is one of the leading causes of maternal and perinatal morbidity and mortality. Till date despite years of research into the condition, predicting the onset of preeclampsia remains a problem. Placental growth factor is one of the many angiogenic factors, which shows significant altered levels in pr...
journal_title：Archives of gynecology and obstetrics
pub_type： 杂志文章
doi：10.1007/s00404-011-1960-4
更新日期：2012-02-01 00:00:00
abstract：:We evaluated the possibility of discovering bleeding causes in late postmenopausal period with cytological examination of material received by endometrial brush in comparison with Pap test and fractionated curettage. Sixty-two women in late postmenopausal period with cervical canal bleeding, treated in gynecological d...
journal_title：Archives of gynecology and obstetrics
pub_type： 杂志文章
doi：10.1007/s00404-002-0414-4
更新日期：2004-05-01 00:00:00
abstract：PURPOSE:The objective of this study was to evaluate the levels of total microparticles (MPs) and microparticles-expressing tissue factor (TFMPs) in women with polycystic ovarian syndrome (PCOS) who use metformin comparing to those who do not take metformin. METHODS:We quantified total MPs and TFMPs in the plasma of 50...
journal_title：Archives of gynecology and obstetrics
pub_type： 杂志文章
doi：10.1007/s00404-017-4471-0
更新日期：2017-10-01 00:00:00
abstract：PURPOSE:To develop an index to predict fetal overgrowth in pregnancies complicated by diabetes. METHODS:Data were derived from a cohort of 275 women with singleton gestations in a collaborative diabetes in pregnancy program. Regression analysis incorporated clinical factors available in the first 20-30 weeks of pregna...
journal_title：Archives of gynecology and obstetrics
pub_type： 杂志文章
doi：10.1007/s00404-018-4758-9
更新日期：2018-07-01 00:00:00
abstract：OBJECTIVE:To evaluate women with delayed childbearing after 35 years and the perinatal profile of their surviving offspring in a low-income country. METHOD:A matched case-control study of advanced maternal age (AMA) parturients above 35 years was compared to younger mothers (20-35 years) in an inner-city maternity hos...
journal_title：Archives of gynecology and obstetrics
pub_type： 杂志文章
doi：10.1007/s00404-011-2105-5
更新日期：2012-04-01 00:00:00
abstract：PURPOSE:The incidence of ectopic pregnancy (EP) in the general population is 2%, whereas the EP rate following assisted reproductive technologies (ART) is between 2.1 and 11%. EP is also an adverse effect of tubal surgery with incidences up to 40% depending on the type, location, and severity of tubal disease and the s...
journal_title：Archives of gynecology and obstetrics
pub_type： 杂志文章
doi：10.1007/s00404-011-2092-6
更新日期：2012-03-01 00:00:00
abstract：OBJECTIVE:This study aimed to determine the relationship between spousal deployment and postpartum depression diagnosis among U.S. military wives, accounting for the timing of deployment with respect to pregnancy and delivery. METHODS:A retrospective cohort study was conducted to evaluate the association between spous...
journal_title：Archives of gynecology and obstetrics
pub_type： 杂志文章
doi：10.1007/s00404-015-3672-7
更新日期：2015-09-01 00:00:00
abstract：AIMS AND OBJECTIVES:To compare the three techniques of hysterectomy-total laparoscopic hysterectomy (TLH), laparoscopic assisted vaginal hysterectomy (LAVH) and non-descent vaginal hysterectomy (NDVH). MATERIALS AND METHODS:Ninety women with benign disease of uterus with failed medical management or not amenable to me...
journal_title：Archives of gynecology and obstetrics
pub_type： 杂志文章,随机对照试验
doi：10.1007/s00404-010-1778-5
更新日期：2011-10-01 00:00:00
abstract：PURPOSE:Preterm birth (PTB) can be categorised according to aetiology into: spontaneous preterm labour (SPL), preterm prelabour rupture of membranes (PPROM), and iatrogenic (iatro) PTB. Outcomes could differ between these groups, which could be of interest in counselling. We aimed to explore differences between aetiolo...
journal_title：Archives of gynecology and obstetrics
pub_type： 杂志文章
doi：10.1007/s00404-020-05673-5
更新日期：2020-10-01 00:00:00
abstract：PURPOSE:The age-standardized incidence rate (ASR) of invasive cervical cancer in Israeli-Jewish women is persistently low compared to many other countries. The aim of the present study was to assess selected demographic characteristics of Israeli-Jewish women with cervical squamous cell carcinoma (SCC) in an attempt to...
journal_title：Archives of gynecology and obstetrics
pub_type： 杂志文章
doi：10.1007/s00404-010-1582-2
更新日期：2011-03-01 00:00:00
abstract：BACKGROUND:Cervical cancer is the second most common cancer of the genital tract. Wide use of screening programs can help in prevention of cervical cancer. OBJECTIVE:To screen and evaluate the prevalence of cervical intraepithelial neoplasia (CIN) by visualization of the cervix after application of 5 % acetic acid (VI...
journal_title：Archives of gynecology and obstetrics
pub_type： 杂志文章
doi：10.1007/s00404-013-3109-0
更新日期：2014-06-01 00:00:00
abstract：BACKGROUND:While there is an increasing interest in incorporating ultrasound in undergraduate medical education and the use of student tutors in conveying this medical skill to assist faculty members, little is known about undergraduate ultrasound teaching in obstetrics and gynecology. METHODS:After a 3 week training ...
journal_title：Archives of gynecology and obstetrics
pub_type： 杂志文章
doi：10.1007/s00404-019-05161-5
更新日期：2019-07-01 00:00:00
abstract：PURPOSE:To estimate the impact of increasing pre-pregnancy Body Mass Index (BMI) on the risk of adverse maternal and perinatal outcomes, in patients who delivered in an Italian tertiary care Obstetric department. METHODS:Data, related to women who delivered at Sant'Anna Hospital, Turin, between 2011 and 2015, were col...
journal_title：Archives of gynecology and obstetrics
pub_type： 杂志文章
doi：10.1007/s00404-019-05093-0
更新日期：2019-04-01 00:00:00
abstract：PURPOSE:To compare the pregnancy and perinatal outcomes of unplanned home or car births vs. in-hospital deliveries. METHODS:A retrospective, case-control study of women who underwent unplanned out-of-hospital deliveries vs. in-hospital deliveries from 2004 through 2014. Matching was based on gestational age and parity...
journal_title：Archives of gynecology and obstetrics
pub_type： 杂志文章
doi：10.1007/s00404-017-4634-z
更新日期：2018-04-01 00:00:00
abstract：PURPOSE:Ovarian ischemia-reperfusion (IR) damage continues to be a serious infertility problem. The oxidative stress plays central role in the development of IR injuries. Activation of antioxidants decreases IR injuries; however, the efficacy of antioxidant agents remains controversial. Unfortunately, there has been no...
journal_title：Archives of gynecology and obstetrics
pub_type： 杂志文章
doi：10.1007/s00404-019-05303-9
更新日期：2019-11-01 00:00:00
abstract：:Primary malignant melanoma (MM) of the uterine cervix is a rare neoplasm. Historically all MMs of the cervix were thought to be metastatic. But after the discovery of melanocytes in the cervix in 1959, it was recognized that primary MM of the cervix exists as a separate entity. The treatment of this condition is not y...
journal_title：Archives of gynecology and obstetrics
pub_type： 杂志文章,评审
doi：10.1007/s00404-008-0912-0
更新日期：2009-09-01 00:00:00
abstract：PURPOSE:Breast ultrasound could be a valuable tool complementary to mammography in breast cancer screening. Automated 3D breast ultrasound (ABUS) addresses challenges of hand-held ultrasound and could allow double reading analysis of ultrasound images. This trial assesses the inter-rater reliability and double reading ...
journal_title：Archives of gynecology and obstetrics
pub_type： 杂志文章
doi：10.1007/s00404-017-4473-y
更新日期：2017-09-01 00:00:00
abstract：BACKGROUND:Type-II endometrial cancer is an estrogen independent and one of the most lethal types of cancer having poor prognosis. Adipokines play a crucial role in the triggering Type-II EMC. In addition, adipokines modulators, therefore, may have beneficial effects in the treatment of Type-II endometrial cancer, whic...
journal_title：Archives of gynecology and obstetrics
pub_type： 杂志文章,评审
doi：10.1007/s00404-019-05181-1
更新日期：2019-08-01 00:00:00
abstract：OBJECTIVE:Case report of a rare combination of a trisomy 18 and 21 in a dizygotic twin pregnancy in a woman with a history of recurrent miscarriage, a neonatal death, no living offspring and Graves disease. METHODS:Case report and literature search. RESULTS:Only one other report in the literature of a combined trisom...
journal_title：Archives of gynecology and obstetrics
pub_type： 杂志文章
doi：10.1007/s00404-007-0378-5
更新日期：2007-11-01 00:00:00
abstract：BACKGROUND AND PURPOSE:Ovarian cancer (OC) is one of the most fatal malignancies in women. High mortality rate may be due to problems with diagnosis in the early stages. The use of new biomarkers for faster diagnosis and selection of more efficient therapies is one of the main concerns in this area. miRNAs are non-codi...
journal_title：Archives of gynecology and obstetrics
pub_type： 杂志文章
doi：10.1007/s00404-019-05107-x
更新日期：2019-05-01 00:00:00
abstract：BACKGROUND:Data on comparative outcomes of abdominal myomectomy for varying uterine sizes that could guide informed decision by women and clinicians in resource-constrained settings are scarce. OBJECTIVE:To evaluate safety of abdominal myomectomy and compare perioperative morbidities for women with very large uterine ...
journal_title：Archives of gynecology and obstetrics
pub_type： 杂志文章
doi：10.1007/s00404-010-1460-y
更新日期：2011-04-01 00:00:00
abstract：OBJECTIVE:The purpose of the present study was to investigate the predictive power of sexual hormones and tumor markers in endometrial cancer. METHODS:A total of 135 healthy women were prospectively compared with 135 women who had histopathologically confirmed endometrial cancer. Both the groups of women were matched ...
journal_title：Archives of gynecology and obstetrics
pub_type： 杂志文章
doi：10.1007/s00404-009-1228-4
更新日期：2010-04-01 00:00:00
abstract：PURPOSE:The aim of this study is to assess the effects of maternal nifedipine administration on placental and fetal blood flow. METHODS:A total of 29 patients with preterm labor diagnosis admitted to the tertiary care center, Zeynep Kamil Hospital, were evaluated. Before and 24-48 h after administration of oral nifedi...
journal_title：Archives of gynecology and obstetrics
pub_type： 杂志文章
doi：10.1007/s00404-018-4839-9
更新日期：2018-10-01 00:00:00
abstract：PURPOSE:WHO sets 24 months as the ideal minimum interpregnancy interval (IPI) to minimize maternal and perinatal adverse outcomes. Some studies suggest that an interval longer than 59 months may affect these outcomes, but little is known about its influence on labor. The primary objective of this study was to compare t...
journal_title：Archives of gynecology and obstetrics
pub_type： 杂志文章
doi：10.1007/s00404-019-05347-x
更新日期：2019-12-01 00:00:00
abstract：BACKGROUND:Splenic cysts or masses in pregnancy are extremely rare and only five cases were described in the literature. We present the first case of splenic cyst in pregnancy treated laparoscopically with fenestration and preservation of the spleen. CASE:A 23-year-old primigravida at 9 weeks of gestation presented fo...
journal_title：Archives of gynecology and obstetrics
pub_type： 杂志文章
doi：10.1007/s00404-006-0229-9
更新日期：2007-04-01 00:00:00
abstract：OBJECTIVE:The objective was to review all obstetric admissions to the intensive care unit (ICU) at the Royal Free Hospital, London, UK, and to identify the risk factors for obstetric admissions to the ICU. METHOD:We carried out a retrospective case-control study. The cases consisted of women admitted to the ICU during...
journal_title：Archives of gynecology and obstetrics
pub_type： 杂志文章
doi：10.1007/s00404-004-0695-x
更新日期：2005-09-01 00:00:00
