Abstract：
PURPOSE:Preeclampsia is one of the leading causes of maternal and perinatal morbidity and mortality. Till date despite years of research into the condition, predicting the onset of preeclampsia remains a problem. Placental growth factor is one of the many angiogenic factors, which shows significant altered levels in preeclampsia compared to normal pregnancy. The present study aims to analyze whether estimation of serum PLGF levels in late second trimester can act as a predictor of preeclampsia. METHODS:A total of 150 nulliparous pregnant women admitted in antenatal wards or attending antenatal clinic were included in the study. They were divided into three groups: 30 women being normotensive and 60 each with diagnosed mild and severe preeclampsia, respectively. Serum samples collected from the study groups were subjected to ELISA, and serum PLGF level was calculated in all the samples. RESULTS:Mean serum PLGF levels were found to be significantly low in mild and severe preeclampsia as compared to normal pregnancy. Serum PLGF levels were highest at 26-28 weeks and were lowered at 28-30 and 30-32 weeks of gestation within each of the three study groups. Cutoff value of serum PLGF levels for predicting mild and severe preeclampsia was calculated statistically from the analyzed data. CONCLUSION:Estimation of serum PLGF levels at 26 weeks of gestation in nulliparous pregnant women can be used as a screening test to identify women at risk for the development of preeclampsia with very high sensitivity.
journal_name
Arch Gynecol Obstetjournal_title
Archives of gynecology and obstetricsauthors
Ghosh SK,Raheja S,Tuli A,Raghunandan C,Agarwal Sdoi
10.1007/s00404-011-1960-4subject
Has Abstractpub_date
2012-02-01 00:00:00pages
417-22issue
2eissn
0932-0067issn
1432-0711journal_volume
285pub_type
杂志文章abstract：BACKGROUND:Our goal is to identify subgroups of women undergoing breast-conserving therapy (BCT) who are at increased risk for requiring a secondary surgical procedure, and to identify tumor and patient profiles that will allow surgeons to anticipate the need for taking larger margins when removing the tumor. METHODS:...
journal_title：Archives of gynecology and obstetrics
pub_type： 杂志文章
doi：10.1007/s00404-012-2401-8
更新日期：2012-10-01 00:00:00
abstract：:Cervical endometriosis is usually a retrospective finding on histology. We describe the diverse symptomatology of the disease, wherein a suspicion of diagnosis may be raised. A series of five patients with cervical endometriosis confirmed on histology was identified. One patient was asymptomatic but examination reveal...
journal_title：Archives of gynecology and obstetrics
pub_type： 杂志文章
doi：10.1007/s00404-005-0006-1
更新日期：2005-10-01 00:00:00
abstract：OBJECTIVE:Aim of the study was to evaluate Evra use in adolescents and compare the outcome with adult users. METHODS:A total of 80 adolescents and 178 adults were followed-up at 1-, 3-, and 6-month interval with their compliance, satisfaction, cycle control, and adverse events being assessed. RESULTS:Compliance rate ...
journal_title：Archives of gynecology and obstetrics
pub_type： 杂志文章
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journal_title：Archives of gynecology and obstetrics
pub_type： 杂志文章
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journal_title：Archives of gynecology and obstetrics
pub_type： 杂志文章
doi：10.1007/s00404-015-3856-1
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journal_title：Archives of gynecology and obstetrics
pub_type： 杂志文章
doi：10.1007/s00404-011-2105-5
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journal_title：Archives of gynecology and obstetrics
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journal_title：Archives of gynecology and obstetrics
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doi：10.1007/s00404-020-05718-9
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journal_title：Archives of gynecology and obstetrics
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journal_title：Archives of gynecology and obstetrics
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journal_title：Archives of gynecology and obstetrics
pub_type： 杂志文章
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journal_title：Archives of gynecology and obstetrics
pub_type： 杂志文章
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更新日期：2003-10-01 00:00:00
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journal_title：Archives of gynecology and obstetrics
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更新日期：2011-02-01 00:00:00
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journal_title：Archives of gynecology and obstetrics
pub_type： 杂志文章
doi：10.1007/s00404-010-1832-3
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journal_title：Archives of gynecology and obstetrics
pub_type： 杂志文章,随机对照试验
doi：10.1007/s00404-005-0014-1
更新日期：2005-12-01 00:00:00
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journal_title：Archives of gynecology and obstetrics
pub_type： 杂志文章,评审
doi：10.1007/BF00934077
更新日期：1989-01-01 00:00:00
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journal_title：Archives of gynecology and obstetrics
pub_type： 杂志文章
doi：10.1007/s00404-001-0255-6
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journal_title：Archives of gynecology and obstetrics
pub_type： 杂志文章
doi：10.1007/s00404-009-1228-4
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abstract：:Tubal sterilization is one of the options chosen by the women who have completed their fertility. Although ectopic pregnancy after tubal sterilization is rare, all women undergoing this procedure should be informed about the risk of it. An ectopic pregnancy in a 36-year-old woman who had undergone tubal sterilization ...
journal_title：Archives of gynecology and obstetrics
pub_type： 杂志文章
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journal_title：Archives of gynecology and obstetrics
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journal_title：Archives of gynecology and obstetrics
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journal_title：Archives of gynecology and obstetrics
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更新日期：2009-06-01 00:00:00
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journal_title：Archives of gynecology and obstetrics
pub_type： 杂志文章
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更新日期：2019-11-01 00:00:00
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journal_title：Archives of gynecology and obstetrics
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更新日期：2020-04-01 00:00:00
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journal_title：Archives of gynecology and obstetrics
pub_type： 临床试验,杂志文章
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更新日期：2011-04-01 00:00:00
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journal_title：Archives of gynecology and obstetrics
pub_type： 杂志文章
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更新日期：2016-05-01 00:00:00
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journal_title：Archives of gynecology and obstetrics
pub_type： 杂志文章
doi：10.1007/s00404-019-05093-0
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journal_title：Archives of gynecology and obstetrics
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doi：10.1007/s00404-020-05536-z
更新日期：2020-05-01 00:00:00
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journal_title：Archives of gynecology and obstetrics
pub_type： 杂志文章
doi：10.1007/s00404-012-2667-x
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journal_title：Archives of gynecology and obstetrics
pub_type： 杂志文章,评审
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