Abstract：
BACKGROUND:Our goal is to identify subgroups of women undergoing breast-conserving therapy (BCT) who are at increased risk for requiring a secondary surgical procedure, and to identify tumor and patient profiles that will allow surgeons to anticipate the need for taking larger margins when removing the tumor. METHODS:One hundred female patients who had palpable, invasive carcinomas of the breast, and had undergone a primary BCT, were included in the study. Of these, all women (n = 25) who had incomplete resections, or questionable margins of resection, had to undergo re-excisions. RESULTS:Patients who had multifocal disease, accompanying ductal carcinoma in situ, involvement of regional lymph nodes, high-grade breast cancer (Grade 3 vs. 1/2), lympho-vascular invasion or negative hormone-receptor-status, were significantly more likely to have undergone incomplete removal of tumor tissue-these patients thus required a secondary surgery. CONCLUSION:The clinical and pathological predictors described above indicate that surgery in breast cancer patients meeting these criteria require larger safety margins to minimize the incidence rate of re-excision at a later date.
journal_name
Arch Gynecol Obstetjournal_title
Archives of gynecology and obstetricsauthors
Rath MG,Heil J,Domschke C,Topic Z,Schneider S,Sinn HP,Marme F,Scharf A,Schneeweiss A,Sohn C,Rom Jdoi
10.1007/s00404-012-2401-8subject
Has Abstractpub_date
2012-10-01 00:00:00pages
1023-31issue
4eissn
0932-0067issn
1432-0711journal_volume
286pub_type
杂志文章abstract：PURPOSE:Modest increases of serum progesterone at human chorionic gonadotrophin (hCG) administration in controlled ovarian hyperstimulation (COH) cycles have been shown to have a negative impact on pregnancy outcomes. The aim of this study was to identify early predictors of progesterone elevation at hCG. DESIGN:Pregn...
journal_title：Archives of gynecology and obstetrics
pub_type： 杂志文章
doi：10.1007/s00404-014-3167-y
更新日期：2014-07-01 00:00:00
abstract：PURPOSE:Silencing of HPV oncogenes or their human host client proteins using topically applied small interfering RNA (siRNA) may be an attractive nonsurgical strategy for CIN treatment. An exploratory clinical investigation was designed to evaluate E6-AP mRNA expression levels in different stages of cervical intraepith...
journal_title：Archives of gynecology and obstetrics
pub_type： 杂志文章
doi：10.1007/s00404-013-3120-5
更新日期：2014-06-01 00:00:00
abstract：INTRODUCTION:The aim of the study was to evaluate the factors that may affect experienced pain during office hysteroscopy performed without anesthesia in an outpatient setting. MATERIALS AND METHODS:We enrolled the patients into six groups, differentiated by parity, menopausal status and type of the sheath that was us...
journal_title：Archives of gynecology and obstetrics
pub_type： 杂志文章
doi：10.1007/s00404-012-2667-x
更新日期：2013-05-01 00:00:00
abstract：INTRODUCTION:Inflammatory bowel disease often affects women during their reproductive years, causing management concerns for obstetricians caring for these patients during pregnancy. TREATMENT:Apart from methotrexate, most drugs used regularly to treat ulcerative colitis and Crohn's disease can safely be used by pregn...
journal_title：Archives of gynecology and obstetrics
pub_type： 杂志文章,评审
doi：10.1007/s00404-003-0489-6
更新日期：2004-09-01 00:00:00
abstract：PURPOSE:This prospective study was carried out in order to investigate changes in nutritional intake during pregnancy with regard to caloric intake and macronutrient composition in normal-weight pregnant women. METHODS:Using food scales, 32 healthy pregnant women estimated their food intake over a period of 2 days at ...
journal_title：Archives of gynecology and obstetrics
pub_type： 杂志文章
doi：10.1007/s00404-009-1328-1
更新日期：2011-02-01 00:00:00
abstract：:The aim of the present study was to evaluate the effect of age and human papillomavirus (HPV) infection associated cellular changes on the predictive value of cervical cytology. In a group of 671 women with Papanicolaou smears suggesting low grade squamous intraepithelial lesion (LSIL), a high grade squamous intraepit...
journal_title：Archives of gynecology and obstetrics
pub_type： 杂志文章
doi：10.1007/BF00634344
更新日期：1995-01-01 00:00:00
abstract：PURPOSE:Both cigarette smoking and alcohol consumption are somehow implicated in sperm function, but the impact of these two lifestyle factors on sperm parameters remains controversial. The present study is focused on the impact of cigarette smoking and alcohol consumption separately and combined on sperm parameters an...
journal_title：Archives of gynecology and obstetrics
pub_type： 杂志文章
doi：10.1007/s00404-014-3281-x
更新日期：2014-10-01 00:00:00
abstract：PURPOSE:Postpartum depression (PPD) stands out as an important health issue that affects not only the mother but her partner and the entire family. A few studies from Turkey have found the high prevalence for PPD. In the current study we aimed: (1) to report the prevalence of postpartum depression among Turkish women i...
journal_title：Archives of gynecology and obstetrics
pub_type： 杂志文章
doi：10.1007/s00404-010-1402-8
更新日期：2011-03-01 00:00:00
abstract：PRESENTATION:We detected an unusual placental lake under the membranes between the two lobes of a placenta bilobate with a turbulent blood flow in it. This was an extraordinary maternal lake: simply the accumulation of maternal blood inside the intervillous space in an area where villous structures were absent between ...
journal_title：Archives of gynecology and obstetrics
pub_type： 杂志文章
doi：10.1007/s00404-004-0649-3
更新日期：2005-01-01 00:00:00
abstract：OBJECTIVE:This study aimed to determine the effectiveness of short-term maintenance treatment with cabergoline and to find out minimum effective dosage of cabergoline during maintenance treatment for patients with microadenoma-related and idiopathic hyperprolactinemia. STUDY DESIGN:Cabergoline was administered orally ...
journal_title：Archives of gynecology and obstetrics
pub_type： 杂志文章,随机对照试验
doi：10.1007/s00404-010-1562-6
更新日期：2010-11-01 00:00:00
abstract：INTRODUCTION:A hemangiopericytoma of the breast is uncommon, and a hemangiopericytoma of the breast is even rarer. Only a few cases of hemangiopericytoma of the breast have been reported in literature. CASE REPORT:Here, we report a case of a 66-year-old woman who presented with a mass in her left breast. The patient h...
journal_title：Archives of gynecology and obstetrics
pub_type： 杂志文章
doi：10.1007/s00404-007-0470-x
更新日期：2008-04-01 00:00:00
abstract：OBJECTIVE:To determine the prevalence of anxiety and gestational depression and to determine the risk factors associated to its development. METHOD:Pregnant women during their third quarter of pregnancy were invited to participate to the study, and they signed an informed consent form. After that, they filled in a gen...
journal_title：Archives of gynecology and obstetrics
pub_type： 杂志文章
doi：10.1007/s00404-014-3508-x
更新日期：2015-05-01 00:00:00
abstract：PURPOSE:The purpose of the study was to investigate the association between gene phosphate and tensin homolog (PTEN) single nucleotide polymorphisms (SNPs) and risk of developing polycystic ovary syndrome (PCOS) in South Indian women. PTEN is one of the most important tumor suppressor genes that regulate cell prolifera...
journal_title：Archives of gynecology and obstetrics
pub_type： 杂志文章
doi：10.1007/s00404-020-05658-4
更新日期：2020-10-01 00:00:00
abstract：:For clinical purposes, diagnostic added value of HE4 is important. Diagnostic knowledge is not provided by answering the question, "How accurate is this test?" (test accuracy research). Diagnostic knowledge is the information needed to answer the question, "What is the probability of the presence or absence of a speci...
journal_title：Archives of gynecology and obstetrics
pub_type： 评论,信件
doi：10.1007/s00404-020-05681-5
更新日期：2020-10-01 00:00:00
abstract：AIM:To evaluate the prognostic significance of p53 expression in epithelial ovarian carcinomas (EOC), and to look for correlations between p53 and other disease parameters. MATERIAL AND METHODS:Immunohistochemical techniques were used to evaluate p53 expression in paraffin-embedded tissue specimens of 50 EOC cases. R...
journal_title：Archives of gynecology and obstetrics
pub_type： 杂志文章
doi：10.1007/s004040100235
更新日期：2002-08-01 00:00:00
abstract：PURPOSE:To investigate the influence of different kinds of endometriotic lesions, especially peritoneal endometriotic implants in pain generation and the pain reduction after surgical excision in a prospective study. METHODS:Fifty-one pre-menopausal patients underwent surgical laparoscopy due to chronic pelvic pain, d...
journal_title：Archives of gynecology and obstetrics
pub_type： 临床试验,杂志文章
doi：10.1007/s00404-008-0921-z
更新日期：2009-09-01 00:00:00
abstract：PURPOSE:To evaluate maternal and neonatal outcomes at and beyond term associated with induction of labor compared to spontaneous onset of labor stratified by week of gestational age. METHODS:In this retrospective cohort study, data form 402,960 singleton pregnancies from the Austria Perinatal Registry were used to est...
journal_title：Archives of gynecology and obstetrics
pub_type： 杂志文章
doi：10.1007/s00404-017-4354-4
更新日期：2017-05-01 00:00:00
abstract：PURPOSE:The aim of this study is to assess the effects of maternal nifedipine administration on placental and fetal blood flow. METHODS:A total of 29 patients with preterm labor diagnosis admitted to the tertiary care center, Zeynep Kamil Hospital, were evaluated. Before and 24-48 h after administration of oral nifedi...
journal_title：Archives of gynecology and obstetrics
pub_type： 杂志文章
doi：10.1007/s00404-018-4839-9
更新日期：2018-10-01 00:00:00
abstract：INTRODUCTION:Carcinoid tumors are uncommon neoplasms in the diffuse peripheral endocrine system. Ovarian carcinoids are rare and can be primary or transplanted. Primary ovarian carcinoids make up approximately 0.5-1.7% of all carcinoid tumors. CASE REPORT:We describe the case of a 55-year-old female patient. A tumor i...
journal_title：Archives of gynecology and obstetrics
pub_type： 杂志文章,评审
doi：10.1007/s00404-010-1600-4
更新日期：2010-10-01 00:00:00
abstract：PURPOSE:Complementary medicine services are nowadays usually quite heterogeneous, and little information is available on standards for running an integrative medicine consultancy service. This study aimed to assess patients' satisfaction with a standardized treatment service on integrative medicine. METHODS:Using a cr...
journal_title：Archives of gynecology and obstetrics
pub_type： 杂志文章
doi：10.1007/s00404-018-4779-4
更新日期：2018-07-01 00:00:00
abstract：BACKGROUND:Implantation failure represents a major cause of stress to both clinician and patient undergoing ICSI cycle. Even minor uterine cavity abnormalities, such as endometrial polyps, small submucous myomas, adhesions, and septa are considered to have a negative impact on the chance to conceive through ICSI. AIM:...
journal_title：Archives of gynecology and obstetrics
pub_type： 杂志文章,随机对照试验
doi：10.1007/s00404-014-3397-z
更新日期：2015-01-01 00:00:00
abstract：OBJECTIVES:Cervical cancer is the most common malignant tumor in female reproductive tract and primarily metastasizes through the lymphatic system that will affect prognosis of patients. Maspin, a member of the serine protease inhibitors (serpins) super family, has recently been indicated as a tumor suppressor in many ...
journal_title：Archives of gynecology and obstetrics
pub_type： 杂志文章
doi：10.1007/s00404-013-2988-4
更新日期：2014-02-01 00:00:00
abstract：:Diet may act as a cofactor in the development of cancer of the cervix. A consistent correlation exists between low tissue concentrations, low serum level, and low intake of vitamin A, beta-carotene, vitamin C, or folic acid and an increased prevalence of cervical neoplasia. A moderate effect is seen in clinical trials...
journal_title：Archives of gynecology and obstetrics
pub_type： 杂志文章,评审
doi：10.1007/BF00933072
更新日期：1989-01-01 00:00:00
abstract：PURPOSE:To test the reliability of the admission test to identify the compromised fetus and thus reduce the neonatal morbidity and mortality by early intervention. METHODS:A prospective analysis over a period of 1 year from December 2007 to December 2008 included 100 antepartum patients and were evaluated for perinata...
journal_title：Archives of gynecology and obstetrics
pub_type： 杂志文章
doi：10.1007/s00404-010-1406-4
更新日期：2010-10-01 00:00:00
abstract：INTRODUCTION:A case report is presented of a 23-year-old patient who was diagnosed with Ehlers Danlos syndrome (EDS) Type IV (vascular type) in the 23rd week of her second pregnancy. EDS Type IV has one of the highest mortality rates for pregnant women of any condition with significant morbidity if the mother survives....
journal_title：Archives of gynecology and obstetrics
pub_type： 杂志文章
doi：10.1007/s00404-011-1899-5
更新日期：2012-01-01 00:00:00
abstract：:We obtained blood samples from 52 patients with pre-eclampsia and from 40 pregnant controls for measurement of plasma urate levels, hematocrit, white cell count and various hemorheological parameters. We also used impedance cardiography to measure cardiac output in both groups and from the results derived values for t...
journal_title：Archives of gynecology and obstetrics
pub_type： 杂志文章,评审
doi：10.1007/BF00934077
更新日期：1989-01-01 00:00:00
abstract：:We present a patient with a tubo-ovarian abscess pathologically confirmed to be actinomycosis in a 44-year-old woman with an intrauterine device (IUD). An ultrasound showed that the IUD was imposed on an apparently degenerated myoma. A pelvic MRI was performed to differentiate the uterine findings from a sarcoma. The ...
journal_title：Archives of gynecology and obstetrics
pub_type： 杂志文章
doi：10.1007/s00404-008-0770-9
更新日期：2009-04-01 00:00:00
abstract：AIM:The aim of this study was to compare the efficacy and safety of two combination regimens in the syndromic management of lower genital infection. Seventy-two non-pregnant women presenting with symptoms of lower genital infection diagnosed as vaginitis on clinical examination and lacking obvious upper genital infecti...
journal_title：Archives of gynecology and obstetrics
pub_type： 临床试验,杂志文章
doi：10.1007/s00404-005-0071-5
更新日期：2006-01-01 00:00:00
abstract：PURPOSE:The role of thyroid function in biochemical markers of first trimester screening has not been assessed. The aim of the present study was to investigate if there were any relation between maternal thyroid hormones and free-beta subunit of human chorionic gonadotropin (fβ-hCG) and pregnancy-associated plasma prot...
journal_title：Archives of gynecology and obstetrics
pub_type： 杂志文章
doi：10.1007/s00404-013-2712-4
更新日期：2013-06-01 00:00:00
abstract：PURPOSE:Publications based on data from perinatal health registries reported worse perinatal health outcomes among women of Turkish origin. The aim of this study was to compare the perinatal outcomes of women of German and Turkish origin in Berlin in two time periods and to analyze if the situation among the women of T...
journal_title：Archives of gynecology and obstetrics
pub_type： 杂志文章
doi：10.1007/s00404-013-2986-6
更新日期：2014-03-01 00:00:00
