Abstract:
BACKGROUND:In women presenting with post-menopausal bleeding (PMB), the incidence of endometrial cancer is 1-10 %; Trans-vaginal scan (TVS) is offered as the first line of investigation to triage women further and a thick endometrium (>4 mm) merits endometrial tissue sampling for further evaluation. When it is difficult and not possible to assess the endometrium sonographically, decision to investigate further lies with the clinician. AIM:Study outcomes for women with PMB and endometrium not assessable on TVS. METHODS:We collected data retrospectively between September 2007 and December 2010. We identified our study group from the radiology database. Data collected include ultrasound findings, methods of endometrial sampling, and the result of cytology/histology. RESULTS:In our study period of 40 months, 671 women with post-menopausal bleeding were referred to the ultrasound department for TVS to assess endometrial thickness. 92 % (614/671) women had the assessment. In 57 women (8 %), endometrial thickness was not assessable and this formed our study group. 3/57 records were not retrievable and excluded from our study. 43/54 (79 %) had some form of endometrial sampling done. Among the 81 % adequate samples (35/43), 7 (20 %) had endometrial cancer; 1 (3 %) had CAH, 1 (3 %) was diagnosed with cervical cancer. In women who had thickened endometrium (>4 mm; n = 448), there were 29 cases of endometrial cancers detected giving an incidence of 6.4 %. In women with PMB and non-assessable endometrial thickness, there is increased incidence of endometrial cancer when compared to the group where endometrial thickness could be measured. (Odds ratio = 3.3 [95 % CI = 1.2-9]). This is a statistically (p = 0.017) and clinically significant finding. CONCLUSION:In women with PMB, there will be a subgroup in which ultrasound cannot assess endometrial thickness. When compared to women where endometrial thickness is measurable, this group stands a higher risk of endometrial cancer and hysteroscopy/ hysterosonography with endometrial sampling is recommended in this group.
journal_name
Arch Gynecol Obstetjournal_title
Archives of gynecology and obstetricsauthors
Ragupathy K,Cawley N,Ridout A,Iqbal P,Alloub Mdoi
10.1007/s00404-013-2746-7subject
Has Abstractpub_date
2013-08-01 00:00:00pages
375-8issue
2eissn
0932-0067issn
1432-0711journal_volume
288pub_type
杂志文章abstract::Vaginoplasty using pelvic peritoneum (Rothman's method) was used in 24 patients with congenital absence of the vagina. The results are presented. Rothman (1972) described vaginoplasty using pelvic peritoneum. We have operated on 24 patients with the anomaly. In this report, the better technique for this operation and ...
journal_title:Archives of gynecology and obstetrics
pub_type: 杂志文章
doi:10.1007/BF02390702
更新日期:1991-01-01 00:00:00
abstract:PURPOSE:To determine whether quadrivalent HPV vaccination is effective in reducing recurrent disease in women with a previous history of HPV disease. METHODS:All women under 45 years of age treated for HPV-linked disease and with negative HPV test, cytology and colposcopy 3 months after treatment were enrolled. Women ...
journal_title:Archives of gynecology and obstetrics
pub_type: 杂志文章,随机对照试验
doi:10.1007/s00404-018-4926-y
更新日期:2018-12-01 00:00:00
abstract:PURPOSE:We aimed to evaluate the effect of an absorbable adhesion barrier (oxidized regenerated cellulose) for the prevention of peritoneal adhesions in women undergoing repeat cesarean delivery (CD). METHODS:This is a retrospective, single center study that included all women who underwent two consecutive CDs, 2011-2...
journal_title:Archives of gynecology and obstetrics
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doi:10.1007/s00404-020-05591-6
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abstract::Urodynamic and morphologic findings in 82 patients with stress urinary incontinence were analysed. All patients had undergone vaginal respectively abdominal hysterectomy with anterior colporrhaphy respectively urethrovesicopexy. Whereas in the abdominal group the urodynamic and morphologic findings improved significan...
journal_title:Archives of gynecology and obstetrics
pub_type: 杂志文章
doi:10.1007/BF02417572
更新日期:1989-01-01 00:00:00
abstract::We describe a postmenopausal woman with 45,XO/46,XX/47,XXX mosaicism who presented with a Sertoli-Leydig cell tumour and a past history of habitual abortion. The cytogenetic finding is discussed in relation to the etiology of the tumour and of the recurrent abortions. ...
journal_title:Archives of gynecology and obstetrics
pub_type: 杂志文章
doi:10.1007/BF00932978
更新日期:1988-01-01 00:00:00
abstract:UNLABELLED:Does local injection with lidocaine plus epinephrine prior to vaginal reconstructive surgery with synthetic mesh affect exposure rates? A retrospective comparison. PURPOSE:To determine if local injection, prior to incision with lidocaine plus epinephrine (L + E) influences the rate of mesh exposure in the e...
journal_title:Archives of gynecology and obstetrics
pub_type: 杂志文章
doi:10.1007/s00404-010-1715-7
更新日期:2011-09-01 00:00:00
abstract:BACKGROUND:Reactive oxygen species (ROS) are an array of molecules including oxygen-centered radicals, which are endowed with one or more unpaired electrons and non-radical oxygen derivatives such as hydrogen peroxide, which behave, to a large extent, like a double-edged sword in human sperm biology. This study aimed t...
journal_title:Archives of gynecology and obstetrics
pub_type: 杂志文章,评审
doi:10.1007/s00404-013-2801-4
更新日期:2013-07-01 00:00:00
abstract:PURPOSE:To identify risk factors for the development of severe perineal lacerations and to give recommendations for their prevention in nulliparous women. METHODS:A retrospective case-control analysis of deliveries at our University Hospital was performed. Multiparae, Caesarean sections, twin pregnancies, fetal breech...
journal_title:Archives of gynecology and obstetrics
pub_type: 杂志文章
doi:10.1007/s00404-009-1063-7
更新日期:2010-01-01 00:00:00
abstract:PURPOSE:The purpose of this investigation was to explore changes in patient preference regarding gynecologist's gender. METHODS:Using a standardized questionnaire, distributed in 1997 and 2018, a total of 1000 women were interviewed about preferences in terms of their choice of gynecologist and perceptions regarding g...
journal_title:Archives of gynecology and obstetrics
pub_type: 历史文章,杂志文章
doi:10.1007/s00404-019-05315-5
更新日期:2019-11-01 00:00:00
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journal_title:Archives of gynecology and obstetrics
pub_type: 杂志文章,评审
doi:10.1007/s00404-006-0136-0
更新日期:2006-07-01 00:00:00
abstract:OBJECTIVE:To evaluate the efficacy and safety of hysteroscopic adhesiolysis in patients with intrauterine adhesions (IUAs). SETTING:Minia Maternity University Hospital, Egypt. DESIGN:Prospective cohort study. PATIENTS:This study included 61 patients presented with infertility (primary or secondary) or recurrent preg...
journal_title:Archives of gynecology and obstetrics
pub_type: 杂志文章
doi:10.1007/s00404-016-4107-9
更新日期:2016-08-01 00:00:00
abstract:PURPOSE:To assess the effects of Kampo, a traditional Japanese adaptation of Chinese herbal medicine, on peri- and postmenopausal women with sleep disturbances. METHODS:Among the records of 1,523 peri- and postmenopausal women who are enrolled in the Health and Nutrition Education Program at the Tokyo Medical and Dent...
journal_title:Archives of gynecology and obstetrics
pub_type: 杂志文章
doi:10.1007/s00404-010-1779-4
更新日期:2011-10-01 00:00:00
abstract:PURPOSE:To analyze the maternal and obstetric outcomes of patients with Alport syndrome. METHODS:We describe the pregnancy course of 8 pregnancies of three family members with the autosomal dominant (the rarest) form of Alport syndrome. We also analyzed 10 previously reported pregnancies with other Alport mutations in...
journal_title:Archives of gynecology and obstetrics
pub_type: 杂志文章
doi:10.1007/s00404-015-3893-9
更新日期:2016-04-01 00:00:00
abstract:BACKGROUND:hTFM in primary vulvar cancer is an important prognostic factor. Ideally, a diameter of > 8 mm should be achieved after primary surgery. The role of VIN III persistence after primary surgery in vulvar cancer is still unclear. The main objective of the current study was to study the role of residual VIN III r...
journal_title:Archives of gynecology and obstetrics
pub_type: 杂志文章
doi:10.1007/s00404-018-4887-1
更新日期:2018-11-01 00:00:00
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journal_title:Archives of gynecology and obstetrics
pub_type: 杂志文章
doi:10.1007/s00404-010-1404-6
更新日期:2011-02-01 00:00:00
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journal_title:Archives of gynecology and obstetrics
pub_type: 杂志文章
doi:10.1007/s00404-019-05236-3
更新日期:2019-09-01 00:00:00
abstract:BACKGROUND:Few case reports describing endometriosis in patients with gonadal dysgenesis have been published, but none has reported the presence of adenomyosis in a patient with Turner's syndrome. CASE:A 31-year-old woman with mosaic Turner's Syndrome (45,X/46,XX/47,XXX) was referred to us because of severe iron defic...
journal_title:Archives of gynecology and obstetrics
pub_type: 杂志文章
doi:10.1007/s00404-004-0603-4
更新日期:2005-03-01 00:00:00
abstract:PURPOSE:Laparoscopy and laparotomy are the two most common surgical options used to treat women with early-stage cervical cancer. This study aimed to examine the volume of hidden blood loss (HBL) between laparoscopy and laparotomy for cervical cancer and to identify its risk factors. METHODS:Sixty-one patients treated...
journal_title:Archives of gynecology and obstetrics
pub_type: 杂志文章
doi:10.1007/s00404-019-05162-4
更新日期:2019-07-01 00:00:00
abstract:PURPOSE:Hysterosalpingography (HSG) is an important tool for evaluation of tubal factors in infertility. It does not require anesthesia but can be a painful procedure. Thus, this study was undertaken to establish the role of intracervical block as pain relief modality for HSG. METHODS:This prospective, randomized stud...
journal_title:Archives of gynecology and obstetrics
pub_type: 杂志文章,随机对照试验
doi:10.1007/s00404-012-2515-z
更新日期:2013-01-01 00:00:00
abstract:INTRODUCTION:Acute appendicitis and symptomatic biliary stones are the most common indications for non-obstetrical surgical procedures during pregnancy. However, combination of these two clinical presentations in the same gestational period is anecdotal. CASE REPORT:A 30-year-old twin pregnant patient complicated with...
journal_title:Archives of gynecology and obstetrics
pub_type: 杂志文章
doi:10.1007/s00404-007-0331-7
更新日期:2007-09-01 00:00:00
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journal_title:Archives of gynecology and obstetrics
pub_type: 杂志文章
doi:10.1007/s00404-005-0100-4
更新日期:2006-04-01 00:00:00
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journal_title:Archives of gynecology and obstetrics
pub_type: 杂志文章
doi:10.1007/s00404-007-0373-x
更新日期:2007-11-01 00:00:00
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journal_title:Archives of gynecology and obstetrics
pub_type: 杂志文章,随机对照试验
doi:10.1007/s00404-010-1599-6
更新日期:2011-07-01 00:00:00
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journal_title:Archives of gynecology and obstetrics
pub_type: 杂志文章,评审
doi:10.1007/s00404-020-05502-9
更新日期:2020-04-01 00:00:00
abstract:PURPOSE:Intercourse during menses is a sexual behavior practiced by 3-30 % of sexually active women. Defense responses of mucosal immunity in the female genital tract regulated by sex hormones would be impaired during menses. The present study seeks to clarify whether unprotected sexual activity during menses will incr...
journal_title:Archives of gynecology and obstetrics
pub_type: 杂志文章
doi:10.1007/s00404-013-2883-z
更新日期:2013-11-01 00:00:00
abstract::There is no cure currently available for HPV infections, although ablative and excisional treatments of some dysplasias often result in a clinical and virological cure. Effective control measures of HPV-associated cancers rely on the prevention at four different levels. Apart from sexual abstinence, primary prevention...
journal_title:Archives of gynecology and obstetrics
pub_type: 杂志文章
doi:10.1007/s00404-013-3011-9
更新日期:2013-11-01 00:00:00
abstract:OBJECTIVE:To compare the efficacy and side effects of 0.2 mg methyl-ergometrine IM, 400 microg misoprostol sublingual and 125 microg 15 methyl PGF2alpha IM in active management of third stage of labor. METHOD:Two hundred low risk pregnant women with induced or spontaneous labor were randomized to receive either 400 mi...
journal_title:Archives of gynecology and obstetrics
pub_type: 杂志文章,随机对照试验
doi:10.1007/s00404-009-1019-y
更新日期:2009-12-01 00:00:00
abstract:INTRODUCTION:Conization of the uterine cervix is a common gynecological procedure that sometimes causes cervical stenosis which creates difficulties for future gynecological procedures. MATERIAL:We present a very unusual case where strenuous effort was needed to obtain safe access to the endocervical canal and endomet...
journal_title:Archives of gynecology and obstetrics
pub_type: 杂志文章
doi:10.1007/s00404-010-1832-3
更新日期:2011-03-01 00:00:00
abstract:INTRODUCTION:Most patients with peripheral arterial occlusion have underlying atherosclerosis. Peripheral arterial thrombosis induced by chemotherapy in gynecological malignancies is rare. CASE REPORT:A 60-year-old woman was diagnosed with ovarian carcinoma coexisting with endometrial carcinoma after surgical histopat...
journal_title:Archives of gynecology and obstetrics
pub_type: 杂志文章
doi:10.1007/s00404-006-0193-4
更新日期:2007-01-01 00:00:00
abstract:PURPOSE:In case of non-gynecological solid tumors and hematological malignancies diagnosed during pregnancy, individual diagnostic and treatment options must be established by an interdisciplinary team. METHODS:In part II of the present review we report on diagnostic and therapeutic principles in distinct entities of ...
journal_title:Archives of gynecology and obstetrics
pub_type: 杂志文章,评审
doi:10.1007/s00404-011-2059-7
更新日期:2011-12-01 00:00:00