Abstract:
PURPOSE:To determine whether quadrivalent HPV vaccination is effective in reducing recurrent disease in women with a previous history of HPV disease. METHODS:All women under 45 years of age treated for HPV-linked disease and with negative HPV test, cytology and colposcopy 3 months after treatment were enrolled. Women were randomly assigned into two groups: a group that received HPV vaccine post treatment and a group that was only submitted to follow-up. Follow-up was performed every 6 months for a duration of at least 3 years. Kaplan-Meier curve was used to estimate the overall disease-free survival during the follow-up period. Statistical analysis was performed by Fisher's exact test. RESULTS:From November 2013 to October 2014, we enrolled a total of 178 women at Careggi University Hospital in Florence and at Azienda USL in Massa Carrara. 12 out of 89 patients in the non-vaccination group recurred (13.5%), while 3 out of 89 patients in the vaccination group recurred (3.4%). The Kaplan-Meier curves showed a statistically difference in the log rank test (p = 0.0147) for the overall disease-free survival in the study groups during follow-up. The rate of recurrence was significantly higher in the non-vaccination group, with a p = 0.0279 by Fisher exact test. CONCLUSION:The introduction of anti-HPV vaccination during the follow-up post treatment for HPV-linked disease is recommended to reduce the risk of recurrence. The clinical implication of this could be very important to influence post-treatment management of HPV disease.
journal_name
Arch Gynecol Obstetjournal_title
Archives of gynecology and obstetricsauthors
Pieralli A,Bianchi C,Auzzi N,Fallani MG,Bussani C,Fambrini M,Cariti G,Scarselli G,Petraglia F,Ghelardi Adoi
10.1007/s00404-018-4926-ysubject
Has Abstractpub_date
2018-12-01 00:00:00pages
1205-1210issue
6eissn
0932-0067issn
1432-0711pii
10.1007/s00404-018-4926-yjournal_volume
298pub_type
杂志文章,随机对照试验abstract:OBJECTIVES:The present study was designed to determine (a) the coagulation parameters, WBC and MPV levels; (b) whether there was any association between androgen and mean platelet volume and low-grade systemic coagulation in PCOS patients. METHODS:A total of 48 patients with non-diabetic PCOS were studied in order to ...
journal_title:Archives of gynecology and obstetrics
pub_type: 杂志文章
doi:10.1007/s00404-008-0884-0
更新日期:2009-08-01 00:00:00
abstract::Hypertensive disorders of pregnancy are associated with an increased risk of maternal and fetal morbidity and mortality. The cause and the pathogenesis of the pregnancy-induced syndrome, preeclampsia, is still poorly understood. Published evidence of altered biomarkers for the endothelial dysfunction suggests that the...
journal_title:Archives of gynecology and obstetrics
pub_type: 杂志文章,评审
doi:10.1007/s00404-010-1538-6
更新日期:2010-11-01 00:00:00
abstract::Primary malignant tumors of the breast are the most frequently occurring neoplasms in women whereas breast metastases are rare. We report the first case, in literature, of metastasis within the breast resulting from a previous cecum carcinoma. We discuss the case and review the literature. ...
journal_title:Archives of gynecology and obstetrics
pub_type: 杂志文章,评审
doi:10.1007/s004040000158
更新日期:2001-11-01 00:00:00
abstract::Urodynamic and morphologic findings in 82 patients with stress urinary incontinence were analysed. All patients had undergone vaginal respectively abdominal hysterectomy with anterior colporrhaphy respectively urethrovesicopexy. Whereas in the abdominal group the urodynamic and morphologic findings improved significan...
journal_title:Archives of gynecology and obstetrics
pub_type: 杂志文章
doi:10.1007/BF02417572
更新日期:1989-01-01 00:00:00
abstract:BACKGROUND:Reactive oxygen species (ROS) are an array of molecules including oxygen-centered radicals, which are endowed with one or more unpaired electrons and non-radical oxygen derivatives such as hydrogen peroxide, which behave, to a large extent, like a double-edged sword in human sperm biology. This study aimed t...
journal_title:Archives of gynecology and obstetrics
pub_type: 杂志文章,评审
doi:10.1007/s00404-013-2801-4
更新日期:2013-07-01 00:00:00
abstract:OBJECTIVE:To investigate the frequency of ruptured uterus, possible etiologic factors and fetomaternal outcomes. STUDY DESIGN:A retrospective chart view of all patients with ruptured uterus over a 9-year period from 1995 to 2003 was carried out. Relevant data relating to the clinical features, characteristics of labou...
journal_title:Archives of gynecology and obstetrics
pub_type: 杂志文章
doi:10.1007/s00404-005-0733-3
更新日期:2005-09-01 00:00:00
abstract:PURPOSE:This prospective study investigated associations between prenatal attachment of adult first-time mothers to the unborn child, perinatal factors and levels of depression before and up to 18 months after delivery. METHOD:Primiparas (N = 161) without specific risk factors answered the following questionnaires dur...
journal_title:Archives of gynecology and obstetrics
pub_type: 杂志文章
doi:10.1007/s00404-012-2286-6
更新日期:2012-08-01 00:00:00
abstract:AIM:To report an unusual location of a transmigrated IUD which become embedded in the right ovary causing chronic pelvic pain and dyspareunia. CASE:A 22-year-old woman who had an IUD (Copper T), inserted 7 years ago presented with complaint of lower abdominal pain. Pelvic ultrasonographic examination revealed ovarian ...
journal_title:Archives of gynecology and obstetrics
pub_type: 杂志文章,评审
doi:10.1007/s00404-008-0882-2
更新日期:2009-08-01 00:00:00
abstract:OBJECTIVE:To review the outcomes of pelvic exenterative surgery done with a palliative intent and evaluate its role in relapsed gynaecology malignancies. METHOD:This is a retrospective cohort study between April 2009 and May 2012 in Oxford Gynaecological Cancer Centre. Patients were identified from the oncology surgic...
journal_title:Archives of gynecology and obstetrics
pub_type: 杂志文章
doi:10.1007/s00404-013-3023-5
更新日期:2014-03-01 00:00:00
abstract::Hepatic infarction is rare in hemolysis, elevated liver enzymes, and low platelets syndrome. We described a case of a 24-year-old woman who was admitted at week 17 of pregnancy with an antiphospholipid syndrome. Magnetic resonance imaging was the imaging modality of choice for diagnosing hepatic infarction, guiding tr...
journal_title:Archives of gynecology and obstetrics
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doi:10.1007/s00404-010-1467-4
更新日期:2011-03-01 00:00:00
abstract:BACKGROUND:Recent studies show that contrast-enhanced ultrasonography (CEUS) using SonoVue has the potential to improve the performance of sentinel lymph node biopsy (SLNB) in patients with early breast cancer. However, the evidence of SLNB using CEUS in patients converting from cN1 to cN0 after neoadjuvant chemotherap...
journal_title:Archives of gynecology and obstetrics
pub_type: 杂志文章
doi:10.1007/s00404-020-05646-8
更新日期:2020-09-01 00:00:00
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journal_title:Archives of gynecology and obstetrics
pub_type: 杂志文章
doi:10.1007/s00404-005-0013-2
更新日期:2005-12-01 00:00:00
abstract:PURPOSE:The occurrence of diminished ovarian reserve (DOR) in women was growing in recent years. Although in vitro fertilization and embryo transfer (IVF-ET) became an effective treatment for DOR, the live-birth (LB) rate remains unsatisfactory. This study aimed to investigate the impact factors of LB rate in women wit...
journal_title:Archives of gynecology and obstetrics
pub_type: 杂志文章
doi:10.1007/s00404-018-4884-4
更新日期:2018-11-01 00:00:00
abstract:PURPOSE:To compare peri-operative outcomes between laparoscopic myomectomy (LM) and laparoscopic hysterectomy (LH) for the treatment of uterine fibroids. METHODS:Retrospective cohort study including 400 women who underwent LH or LM for the management of uterine fibroids. RESULTS:LH patients were older, with higher BM...
journal_title:Archives of gynecology and obstetrics
pub_type: 杂志文章
doi:10.1007/s00404-014-3434-y
更新日期:2015-03-01 00:00:00
abstract:OBJECTIVE:The study aimed at determining the prevalence and associated risk factors for gestational diabetes mellitus (GDM) among antenatal women attending the Jos University Teaching Hospital (JUTH), Jos, Nigeria. METHODS:A cross-sectional study was done between February and April 2009 among 265 pregnant women enroll...
journal_title:Archives of gynecology and obstetrics
pub_type: 杂志文章
doi:10.1007/s00404-012-2649-z
更新日期:2013-05-01 00:00:00
abstract:INTRODUCTION:The high incidence of multiple pregnancies is a major concern in the treatment of infertility by in vitro fertilization (IVF). Risks and costs are associated with multiple pregnancies and it is important to find a way to decrease multiple pregnancies. The standard protocol for IVF includes the transfer of ...
journal_title:Archives of gynecology and obstetrics
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1007/s00404-003-0513-x
更新日期:2004-09-01 00:00:00
abstract::We describe a postmenopausal woman with 45,XO/46,XX/47,XXX mosaicism who presented with a Sertoli-Leydig cell tumour and a past history of habitual abortion. The cytogenetic finding is discussed in relation to the etiology of the tumour and of the recurrent abortions. ...
journal_title:Archives of gynecology and obstetrics
pub_type: 杂志文章
doi:10.1007/BF00932978
更新日期:1988-01-01 00:00:00
abstract:PURPOSE:The present meta-analysis aims to assess the efficacy of cervical cerclage retention after the occurrence of preterm premature rupture of the membranes by analyzing the observed maternal and neonatal perinatal outcomes. METHODS:We searched Medline (1966-2014), Scopus (2004-2014), Clinicaltrials.org (1997-2014)...
journal_title:Archives of gynecology and obstetrics
pub_type: 杂志文章,评审
doi:10.1007/s00404-014-3551-7
更新日期:2015-04-01 00:00:00
abstract:INTRODUCTION:Worldwide, 20-30 million people are estimated to be infected with HTLV. HTLV-1 is endemic in Western Africa and Southern Japan, whereas HTLV-2 is considered to be spread among native American people. MATERIALS AND METHODS:The impact of HTLV in gynaecology and obstetrics is being reviewed. Search strategy ...
journal_title:Archives of gynecology and obstetrics
pub_type: 杂志文章,评审
doi:10.1007/s00404-010-1559-1
更新日期:2010-11-01 00:00:00
abstract::A 20-year-old primigravida initially diagnosed at 28 weeks to have superfetation in a case of a bicornuate uterus was subsequently found to have uterus pseudo didelphys during a cesarean section at 35 weeks. This type of uterine anomaly with twin gestation has been previously reported in five case reports, but superfe...
journal_title:Archives of gynecology and obstetrics
pub_type: 杂志文章
doi:10.1007/s00404-002-0349-9
更新日期:2003-08-01 00:00:00
abstract:OBJECTIVES:Total parenteral nutrition (TPN) presumably benefits cancer patients although reports have disputed the significance of this nutritional intervention. We sought to compare the postoperative outcomes of ovarian cancer patients treated with either TPN or conservative management. METHODS:We retrospectively eva...
journal_title:Archives of gynecology and obstetrics
pub_type: 杂志文章
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更新日期:2017-02-01 00:00:00
abstract:INTRODUCTION:The main goal of this retrospective cohort study is the assessment of the effects of administration of recombinant-hCG (r-hCG) versus urinary-hCG (u-hCG) on follicular fluid (FF) composition of women who underwent in vitro fertilization (IVF) treatments. MATERIALS AND METHODS:We selected 70 patients with ...
journal_title:Archives of gynecology and obstetrics
pub_type: 杂志文章
doi:10.1007/s00404-020-05609-z
更新日期:2020-09-01 00:00:00
abstract:OBJECTIVE:The aim of our study was to examine the effect of the levonorgestrel-releasing intrauterine system (LNG-IUS) treatment on depressive symptoms, changes in bleeding patterns, and quality of life (QoL) among premenopausal women in our clinic. MATERIALS AND METHODS:We recruited 120 premenopausal women, aged 18-5...
journal_title:Archives of gynecology and obstetrics
pub_type: 杂志文章
doi:10.1007/s00404-014-3237-1
更新日期:2014-09-01 00:00:00
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journal_title:Archives of gynecology and obstetrics
pub_type: 杂志文章
doi:10.1007/s00404-013-2963-0
更新日期:2014-01-01 00:00:00
abstract:BACKGROUND:Membranous dysmenorrhea is a rare entity involving expulsion of fragments of endometrium retaining the shape of the uterus. The condition is often linked to high progesterone levels. An association with a chronic fatigue syndrome was never described. CASE:A 44-year-old woman with a chronic fatigue syndrome ...
journal_title:Archives of gynecology and obstetrics
pub_type: 杂志文章,评审
doi:10.1007/s00404-008-0795-0
更新日期:2009-05-01 00:00:00
abstract:PURPOSE:The objective of this study was to investigate the effect of decision-to-delivery interval of crash emergency cesarean section on Apgar and umbilical artery pH in a level-3 university hospital. MATERIALS AND METHODS:In a retrospective analysis, all women undergoing "crash" emergency cesarean section were evalu...
journal_title:Archives of gynecology and obstetrics
pub_type: 杂志文章
doi:10.1007/s00404-005-0045-7
更新日期:2005-12-01 00:00:00
abstract::In the original article publication, the authors given name and family name were interchanged. ...
journal_title:Archives of gynecology and obstetrics
pub_type: 已发布勘误
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更新日期:2019-10-01 00:00:00
abstract:INTRODUCTION:There is no established treatment for vaginal cancer at present. Cases of squamous cell carcinoma reported in the literature have been treated primarily by radiotherapy. We report a case of pT4 vaginal adenocarcinoma, in which radical surgery seemed to prolong the disease-free period. ...
journal_title:Archives of gynecology and obstetrics
pub_type: 杂志文章,评审
doi:10.1007/s00404-003-0522-9
更新日期:2003-08-01 00:00:00
abstract:BACKGROUND:While there is an increasing interest in incorporating ultrasound in undergraduate medical education and the use of student tutors in conveying this medical skill to assist faculty members, little is known about undergraduate ultrasound teaching in obstetrics and gynecology. METHODS:After a 3 week training ...
journal_title:Archives of gynecology and obstetrics
pub_type: 杂志文章
doi:10.1007/s00404-019-05161-5
更新日期:2019-07-01 00:00:00
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journal_title:Archives of gynecology and obstetrics
pub_type: 杂志文章
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更新日期:2016-04-01 00:00:00