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Peripheral arterial thrombosis induced by chemotherapy in ovarian carcinoma coexisted with endometrial carcinoma.

Abstract：

INTRODUCTION:Most patients with peripheral arterial occlusion have underlying atherosclerosis. Peripheral arterial thrombosis induced by chemotherapy in gynecological malignancies is rare. CASE REPORT:A 60-year-old woman was diagnosed with ovarian carcinoma coexisting with endometrial carcinoma after surgical histopathological examination. Chemotherapy was started on postoperative day 11. On day 2 of chemotherapy, she developed bilateral lower extremity cyanosis. Thrombocytopenia due to chemotherapy was diagnosed and treated with repeated platelet transfusions. Anticoagulant therapy was also continued. However, the patient worsened steadily and died of liver dysfunction due to multiple liver metastases. CONCLUSION:Although arterial thrombosis induced by chemotherapy is rare, it is important for physicians to consider this possibility in the course of treatment with cytotoxic agents because this complication has serious health implications.

journal_name

Arch Gynecol Obstet

journal_title

Archives of gynecology and obstetrics

authors

Hida K,Ikeda S,Shimizu S,Yoshikata R,Orito S,Tatsuduki A,Ohta H

doi

10.1007/s00404-006-0193-4

subject

Has Abstract

pub_date

2007-01-01 00:00:00

pages

63-5

issue

1

eissn

0932-0067

issn

1432-0711

journal_volume

275

pub_type

杂志文章

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