Abstract:
PURPOSE:Non-gestational ovarian choriocarcinoma (NGOC) is a rare malignant germ cell tumor. Through literature review and cases collection, we aim to analyze prognostic factors for NGOC and summarize its clinicopathological characteristics to guide the individualized treatment. METHODS:We searched PubMed database, Cochrane library, and Google Scholar for cases published between January 1, 1967 and July 31, 2018 using various search terms. We retrieved patients' clinicopathological characteristics, treatment, and prognosis information from included studies. These patients were divided into two groups: died (case group) or alive (control group) group. We summarized and compared their clinical (age, symptoms, R0 resection, serum HCG levels, chemotherapy regimen) and pathological (pure vs non-pure type, tumor size, tumor location, metastasis sites, stage) features by statistical analysis. RESULTS:Only 39 patients were retrieved from 36 studies in total. The median age was 30 years (range 12- to 65-years old). The peak incidence was in the adolescent age 12-25 years. Median follow-up was 20.3 months (range 1-84 months). 9 (23%) patients died; 24 (62%) patients were alive; 6 (15%) were lost to follow-up. Upon univariate analysis, we found age had a poor impact on overall survival (OS) in NGOC, HR - 0.057, 95% CI - 0.111 to - 0.004. Pure type NGOC has a better OS than mixed type, HR - 2.621, 95% CI - 4.577 to - 0.666. R0 resection is a good prognostic factor for OS, HR 2.967, 95% CI 0.709-5.224. CONCLUSION:Clinicians should try to achieve R0 resection to improve the prognosis for NGOC patients even among advanced patients.
journal_name
Arch Gynecol Obstetjournal_title
Archives of gynecology and obstetricsauthors
Liu X,Zhang X,Pang Y,Ma Y,Zhang X,Liu Pdoi
10.1007/s00404-020-05502-9subject
Has Abstractpub_date
2020-04-01 00:00:00pages
901-912issue
4eissn
0932-0067issn
1432-0711pii
10.1007/s00404-020-05502-9journal_volume
301pub_type
杂志文章,评审abstract:PURPOSE:To investigate the influence of different kinds of endometriotic lesions, especially peritoneal endometriotic implants in pain generation and the pain reduction after surgical excision in a prospective study. METHODS:Fifty-one pre-menopausal patients underwent surgical laparoscopy due to chronic pelvic pain, d...
journal_title:Archives of gynecology and obstetrics
pub_type: 临床试验,杂志文章
doi:10.1007/s00404-008-0921-z
更新日期:2009-09-01 00:00:00
abstract::Preeclampsia is a big problem in obstetrics. The diagnosis relies mainly on the detection of both hypertension and proteinuria. The gold standard for the determination of proteinuria is 24 h urinary protein creatinine ratio; however, this approach is inconvenient and it is a considerable time consuming process that mi...
journal_title:Archives of gynecology and obstetrics
pub_type: 信件,meta分析
doi:10.1007/s00404-009-1167-0
更新日期:2010-03-01 00:00:00
abstract:OBJECTIVE:The aim of this study was to evaluate the effect of postpartum counseling on postpartum contraceptive use. METHODS:One hundred and forty-three women who delivered between 1 January 2004 and 31 September 2004 and counseled about postpartum contraception were included in the study. The participants were interv...
journal_title:Archives of gynecology and obstetrics
pub_type: 杂志文章
doi:10.1007/s00404-006-0287-z
更新日期:2007-06-01 00:00:00
abstract:OBJECTIVE:To evaluate the neovascularization in placental polyp tissue by computed tomographic angiography and to determine the need for uterine artery embolization before hysteroscopic resection. STUDY DESIGN:Seventeen consecutive women with suspected placental polyp were enrolled in this retrospective study. Neovasc...
journal_title:Archives of gynecology and obstetrics
pub_type: 杂志文章
doi:10.1007/s00404-009-1161-6
更新日期:2010-05-01 00:00:00
abstract::In the previous decade, the prevalence of HBs-Ag positivity and the anti-HCV positivity declined in Turkey. We aimed to investigate the prevalences of HBs Ag and anti-HCV positivity in pregnant women in Ankara, the capital city of Turkey, while the vertical transmission should be important way of HBV and HCV transmiss...
journal_title:Archives of gynecology and obstetrics
pub_type: 信件
doi:10.1007/s00404-009-1145-6
更新日期:2010-02-01 00:00:00
abstract:PURPOSE:To analyze the effect of Chlamydia trachomatis (C. trachomatis) on adverse pregnancy outcomes based on the currently available evidence. METHODS:Multiple databases were comprehensively searched from the available date of inception through December 9, 2019. The effect of C. trachomatis on adverse pregnancy outc...
journal_title:Archives of gynecology and obstetrics
pub_type: 杂志文章,meta分析,评审
doi:10.1007/s00404-020-05664-6
更新日期:2020-09-01 00:00:00
abstract::A kit using mouse monoclonal antibody against human alpha-fetoprotein (anti-AFP kit) has been developed. Cervical secretion (n = 34) and vaginal fluid (n = 15) was obtained from 30 pregnant volunteers. All 31 specimens obtained from women with intact membranes tested negative while all 18 specimens from women with pre...
journal_title:Archives of gynecology and obstetrics
pub_type: 杂志文章
doi:10.1007/BF00634709
更新日期:1995-01-01 00:00:00
abstract:OBJECTIVE:To investigate the differences in steroid receptor expression patterns between glandular and stromal portions in endometrial polyps among premenopausal and postmenopausal patients and the relationship between the receptor expression in endometrial polyps and clinical parameters. MATERIALS AND METHODS:A total...
journal_title:Archives of gynecology and obstetrics
pub_type: 杂志文章
doi:10.1007/s00404-009-1142-9
更新日期:2010-03-01 00:00:00
abstract:INTRODUCTION:Craniosynostosis is a condition characterized by a premature closure of one or more skull sutures and refers to a wide spectrum of cranial malformation with an estimated birth of 1:2,000-1:4,000 live births. Four receptors (FGFR 1, FGFR 2, FGFR 3, FGFR 4) involving mutation in the fibroblast growth factor ...
journal_title:Archives of gynecology and obstetrics
pub_type: 杂志文章,评审
doi:10.1007/s00404-010-1643-6
更新日期:2011-04-01 00:00:00
abstract:PURPOSE:To compare the subjective and objective cure rates, postoperative pain, postoperative complications, and postoperative quality of life of adjustable single-incision sling (Ajust®) versus tension-free vaginal tape-obturator (TVT-O™) in the treatment of female stress urinary incontinence (SUI). METHODS:Female pa...
journal_title:Archives of gynecology and obstetrics
pub_type: 杂志文章,随机对照试验
doi:10.1007/s00404-015-3949-x
更新日期:2016-02-01 00:00:00
abstract:OBJECTIVE:To investigate whether episiotomy prevents 3rd or 4th degree perineal tears in critical conditions such as shoulder dystocia, instrumental deliveries (vacuum or forceps), persistent occiput-posterior position, fetal macrosomia (>4,000 g), and non-reassuring fetal heart rate (NRFHR) patterns. METHODS:A retros...
journal_title:Archives of gynecology and obstetrics
pub_type: 杂志文章
doi:10.1007/s00404-012-2460-x
更新日期:2012-12-01 00:00:00
abstract::The hematogenous spread from vulvar cancer is extremely rare. We reported an unusual case of ovarian recurrence from vulvar carcinoma. A 78-year-old woman, with a previous (41 months before) diagnosis of vulvar cancer, was admitted to our Institution. Ultrasound revealed a solid mass of the left ovary. Fluorodeoxygluc...
journal_title:Archives of gynecology and obstetrics
pub_type: 杂志文章
doi:10.1007/s00404-008-0585-8
更新日期:2008-10-01 00:00:00
abstract:PURPOSE:The aim of this study was to investigate the impact of bacterial vaginal flora on life-birth rate during ICSI and influence of metronidazole as antibiotic treatment course before ICSI. METHOD:We enrolled 71 women who were undergoing ICSI. At embryo transfer (ET), all of the women had quantitative vaginal cultu...
journal_title:Archives of gynecology and obstetrics
pub_type: 杂志文章
doi:10.1007/s00404-011-1857-2
更新日期:2011-12-01 00:00:00
abstract:BACKGROUND:MicroRNAs (miRNAs) have been increasingly exploited in human malignancies. The regulation of microRNA-455-5p (miR-455-5p) has been shown in several cancers, except for cervical carcinoma. Therefore, the role of miR-455-5p was exploited in cervical carcinoma. METHODS:The qRT-PCR experiment was used to assess...
journal_title:Archives of gynecology and obstetrics
pub_type: 杂志文章
doi:10.1007/s00404-020-05536-z
更新日期:2020-05-01 00:00:00
abstract:PURPOSE:To evaluate at 11-13 weeks' gestation biochemical markers that may predict complications of pregnancy such as pre-eclampsia, proteinuria, and hypertension. METHODS:Analyses were performed on first-morning urine and plasma samples from first trimester pregnant women with increased risk of developing pre-eclamps...
journal_title:Archives of gynecology and obstetrics
pub_type: 杂志文章
doi:10.1007/s00404-016-4111-0
更新日期:2016-11-01 00:00:00
abstract:PURPOSE:The aim of this study was to evaluate the relationship between serum beta-human chorionic gonadotropin (β-hCG) and preeclampsia (PE) and the effects of βhCG on maternal and perinatal outcomes. METHODS:This case-control study included 125 pregnant women who were admitted to the labor ward of the Maternity Teach...
journal_title:Archives of gynecology and obstetrics
pub_type: 杂志文章
doi:10.1007/s00404-019-05041-y
更新日期:2019-03-01 00:00:00
abstract:PURPOSE:To identify whether CGRP and PTHrP serve as screening biomarkers for early detection of preeclampsia or even before the development of preeclampsia in early pregnancy. METHODS:It was a nested case-control study. The subjects were divided into normotensive (controls) and preeclamptic (cases) groups. Serum sampl...
journal_title:Archives of gynecology and obstetrics
pub_type: 杂志文章
doi:10.1007/s00404-014-3303-8
更新日期:2014-11-01 00:00:00
abstract:OBJECTIVE:To compare the IVF/ICSI outcomes of the long GnRH agonist and the fixed GnRH antagonist protocol in women with PCOS. DESIGN:Randomized controlled trial. SETTING:Baskent University Department of Obstetrics and Gynecology. PATIENTS:Three hundred women with PCOS. INTERVENTIONS:IVF/ICSI following the long GnR...
journal_title:Archives of gynecology and obstetrics
pub_type: 杂志文章,随机对照试验
doi:10.1007/s00404-012-2348-9
更新日期:2012-09-01 00:00:00
abstract:INTRODUCTION:With an estimated incidence of one to two per one million women, the endometrial stromal sarcoma (ESS) is a rare disease. It is subclassified into a high-grade and a prognostically better low-grade type. Evidence-based data for a standardized therapy is lacking. CASE REPORT:A 32-year-old obese nulligravid...
journal_title:Archives of gynecology and obstetrics
pub_type: 杂志文章
doi:10.1007/s00404-005-0100-4
更新日期:2006-04-01 00:00:00
abstract:OBJECTIVE:To determine the perinatal outcome associated with cup detachment during vacuum-assisted vaginal delivery (VAVD). METHODS:A retrospective cohort study of all women attempting VAVD in a tertiary hospital (2012-2014). Singleton-term pregnancies were included. Antepartum fetal death and major fetal structural o...
journal_title:Archives of gynecology and obstetrics
pub_type: 杂志文章
doi:10.1007/s00404-017-4507-5
更新日期:2017-11-01 00:00:00
abstract:OBJECTIVE:To determine the prognostic value of the immunohistochemical evaluation of the multidrug resistance-associated protein 2 (MRP2) expression, together with its subcellular localization in primary fallopian tube carcinomas (PFTCs). METHODS:The immunohistochemical analysis was performed using samples originating...
journal_title:Archives of gynecology and obstetrics
pub_type: 杂志文章
doi:10.1007/s00404-012-2589-7
更新日期:2013-03-01 00:00:00
abstract:PURPOSE:Prevention of postpartum haemorrhage (PPH) is essential in the pursuit of improved health care for women. Oxytocin, the most commonly used uterotonic agent to prevent PPH, has no established the route of administration. In this study we aimed to compare whether the mode of oxytocin administration, i.e., intrave...
journal_title:Archives of gynecology and obstetrics
pub_type: 杂志文章,随机对照试验
doi:10.1007/s00404-016-4060-7
更新日期:2016-11-01 00:00:00
abstract::The use of GnRH antagonists has revolutionized ovarian stimulation for assisted reproduction. Two GnRH antagonists are clinically available, namely, cetrorelix and ganirelix. Several studies have directly compared these new stimulation protocols against the long GnRH agonist protocol. To evaluate whether there is a re...
journal_title:Archives of gynecology and obstetrics
pub_type: 杂志文章,meta分析
doi:10.1007/s00404-001-0267-2
更新日期:2001-11-01 00:00:00
abstract:PURPOSE:Pelvic organ prolapse (POP) presents a common benign condition in women associated with reduced quality of life (QoL). The use of pessaries is considered a first-line treatment of POP. However, pessaries can cause perforations into adjacent organs resulting in fistulas. We present a series of three cases of rec...
journal_title:Archives of gynecology and obstetrics
pub_type: 新闻
doi:10.1007/s00404-020-05602-6
更新日期:2020-08-01 00:00:00
abstract::The current management of patients with cervical polyps may include different approaches and protocols, such as a simply removal of the polyp in most cases at an office setting, surgical dilatation and curettage, electrosurgical excision or hysteroscopic polypectomy. Exploration of the cervical canal and uterine cavit...
journal_title:Archives of gynecology and obstetrics
pub_type: 杂志文章,评审
doi:10.1007/s00404-007-0417-2
更新日期:2007-10-01 00:00:00
abstract:AIM:Polycystic ovary syndrome (PCOS) is a complex disorder with gynecological, metabolic and carcinogenic effects. Increased intestinal permeability is related with obesity, insulin resistance, type 1 and 2 diabetes mellitus. The existence of such a relationship between PCOS and intestinal permeability has come to an e...
journal_title:Archives of gynecology and obstetrics
pub_type: 杂志文章
doi:10.1007/s00404-019-05345-z
更新日期:2019-12-01 00:00:00
abstract:PURPOSE:This systematic review and meta-analysis aimed to compare the effectiveness of unilateral vs. bilateral laparoscopic ovarian drilling (ULOD vs. BLOD) for improving fertility outcomes in infertile women with clomiphene-resistant polycystic ovary syndrome (PCOS) as well as its effect on ovarian reserve. METHODS:...
journal_title:Archives of gynecology and obstetrics
pub_type: 杂志文章,meta分析,评审
doi:10.1007/s00404-018-4680-1
更新日期:2018-04-01 00:00:00
abstract:PURPOSE:To assess the effects of Kampo, a traditional Japanese adaptation of Chinese herbal medicine, on peri- and postmenopausal women with sleep disturbances. METHODS:Among the records of 1,523 peri- and postmenopausal women who are enrolled in the Health and Nutrition Education Program at the Tokyo Medical and Dent...
journal_title:Archives of gynecology and obstetrics
pub_type: 杂志文章
doi:10.1007/s00404-010-1779-4
更新日期:2011-10-01 00:00:00
abstract:OBJECTIVE:Effective cytotoxic treatment options for advanced cervical cancer are exceedingly limited. Therefore, interest has increased in targeted therapeutics for the treatment of cervical cancer. Cetuximab, a monoclonal antibody, binds specifically to the epidermal growth factor receptor (EGFR) and competitively inh...
journal_title:Archives of gynecology and obstetrics
pub_type: 杂志文章
doi:10.1007/s00404-010-1389-1
更新日期:2011-01-01 00:00:00
abstract:PURPOSE:To evaluate maternal-fetal outcomes in women of advanced maternal age (AMA; >35 years old) and women of physiological maternal age as controls (C; <35 years old). METHODS:Single-center, retrospective case-control analysis, from January 1 to December 31, 2013. For each group, we evaluated obstetric history, num...
journal_title:Archives of gynecology and obstetrics
pub_type: 杂志文章
doi:10.1007/s00404-014-3367-5
更新日期:2014-12-01 00:00:00