Effective of metronidazole to bacterial flora in vagina and the impact of microbes on live birth rate during intracytoplasmic sperm injection (ICSI).


PURPOSE:The aim of this study was to investigate the impact of bacterial vaginal flora on life-birth rate during ICSI and influence of metronidazole as antibiotic treatment course before ICSI. METHOD:We enrolled 71 women who were undergoing ICSI. At embryo transfer (ET), all of the women had quantitative vaginal culture, ET catheter-tip culture, and vaginal Gram stain scored for bacterial vaginosis. RESULTS:The overall live birth rate (LBR) was 36.6% (26/71), and the rate of early pregnancy loss was 13% (4/30). In women with bacterial vaginosis, intermediate flora and normal flora, the conception rates were 35% (9/26), 42% (14/33) and 58% (7/12), respectively (p = 0.06 for trend). Metronidazole effect to bacterial flora in vaginal. The predominant species isolated from the tip of the embryo transfer catheter in negative pregnancy was Staphylococcus epidermidis (7 vs. 15.2%), and Streptococcus viridians (11 vs. 24%). CONCLUSIONS:Woman with bacterial vaginosis and with a decreased vaginal concentration of hydrogen peroxide-producing lactobacilli may have decreased conception rates and increased rates of failed pregnancy. A larger prospective treatment trial designed to evaluate the impact on ICSI outcomes of optimizing the vaginal flora prior to ICSI may be warranted.


Arch Gynecol Obstet


Selim SA,El Alfy SM,Aziz MH,Mohamed HM,Alasbahi AA




Has Abstract


2011-12-01 00:00:00












  • Amniotic fluid CA-125 as a marker of intra-amniotic inflammation associated with preterm delivery: a preliminary single center study.

    abstract:OBJECTIVE:The purpose of this study was to investigate whether amniotic fluid (AF) CA-125 in patients with preterm labor or preterm premature rupture of membranes can help predict intra-amniotic inflammation (IAI), microbial invasion of the amniotic cavity (MIAC) and imminent delivery. METHODS:We recruited 36 women wh...

    journal_title:Archives of gynecology and obstetrics

    pub_type: 杂志文章


    authors: Seong WJ

    更新日期:2016-01-01 00:00:00

  • Complications of acute fatty liver of pregnancy treated with activated protein C.

    abstract:INTRODUCTION:Acute fatty liver (AFL) of pregnancy is a difficult and challenging diagnosis. The treatment plan is usually supportive. CASE REPORT:We present a case of a patient with AFL of pregnancy and Gram-negative endomyometritis and sepsis. Our treatment plan included the use of activated protein C (APC). CONCLUS...

    journal_title:Archives of gynecology and obstetrics

    pub_type: 杂志文章


    authors: MacLean AA,Almeida Z,Lopez P

    更新日期:2005-12-01 00:00:00

  • Homozygous factor V Leiden mutation in a woman with multiple adverse pregnancy outcomes.

    abstract::We report a case with one intrauterine fetal death (IUFD) at 32 weeks of gestation, one premature delivery at the same week, and one abortion of unknown etiology at 12 weeks of gestation. We discuss that the presence of homozygosity for Factor V Leiden may be associated with placental insufficiency in this woman. Appl...

    journal_title:Archives of gynecology and obstetrics

    pub_type: 杂志文章


    authors: Pauer HU,Neesen J,Schloesser M,Hinney B,Rauskolb R

    更新日期:2000-11-01 00:00:00

  • Fetal therapy in twin reserve arterial perfusion sequence pregnancies with alcohol ablation or bipolar cord coagulation.

    abstract:OBJECTIVE:We aimed to evaluate perinatal outcome of seven pregnancies with twin reserve arterial perfusion sequence. MATERIALS AND METHODS:Study group included seven cases of acardiac twins. Out of seven acardiac twins, two cases were followed without interventions. We performed four alcohol ablation and one bipolar c...

    journal_title:Archives of gynecology and obstetrics

    pub_type: 杂志文章


    authors: Gul A,Gungorduk K,Yildirim G,Gedikbasi A,Yildirim D,Ceylan Y

    更新日期:2009-04-01 00:00:00

  • Ultrasound-guided transversus abdominal plane block with multimodal analgesia for pain management after total abdominal hysterectomy.

    abstract:BACKGROUND:Transversus abdominis plane (TAP) block has been shown to provide pain relief after abdominal procedures. However, TAP block combined with multimodal analgesia technique have not been assessed in a randomized controlled trial. This randomized, controlled, observer-blinded study was designed to evaluate the a...

    journal_title:Archives of gynecology and obstetrics

    pub_type: 杂志文章,随机对照试验


    authors: Gasanova I,Grant E,Way M,Rosero EB,Joshi GP

    更新日期:2013-07-01 00:00:00

  • Obstructive anuria due to blood clot.

    abstract::An unusual case of anuria due to the obstruction caused by blood clot following repair of ruptured uterus is presented. Although the blood clot usually dissolves, the awareness of this complication is important to avoid the unnecessary procedures. ...

    journal_title:Archives of gynecology and obstetrics

    pub_type: 信件


    authors: Gupta A,Nanda S,Singhal SR,Gupta A

    更新日期:2008-10-01 00:00:00

  • Influence of reactive oxygen species on human sperm functions and fertilizing capacity including therapeutical approaches.

    abstract:BACKGROUND:Reactive oxygen species (ROS) are an array of molecules including oxygen-centered radicals, which are endowed with one or more unpaired electrons and non-radical oxygen derivatives such as hydrogen peroxide, which behave, to a large extent, like a double-edged sword in human sperm biology. This study aimed t...

    journal_title:Archives of gynecology and obstetrics

    pub_type: 杂志文章,评审


    authors: Chen SJ,Allam JP,Duan YG,Haidl G

    更新日期:2013-07-01 00:00:00

  • What happens after randomised controlled trials? Uterine fibroids and ulipristal acetate: systematic review and meta-analysis of "real-world" data.

    abstract:PURPOSE:"Real-world" data incorporates studies performed outside of controlled environments, allowing for a better understanding of the effects of treatment in routine clinical practice. We, therefore, performed a systematic review to summarise available "real-world studies" reporting on the use of ulipristal acetate (...

    journal_title:Archives of gynecology and obstetrics

    pub_type: 杂志文章,评审


    authors: Shah N,Egbase E,Sideris M,Odejinmi F

    更新日期:2021-01-02 00:00:00

  • The prognostic implications of anaemia in the outcome of patients with early stages of uterine cervix carcinoma.

    abstract::We studied the prognostic value of anaemia in the evolution of patients with early stages of uterine cervix cancer and treated with radical surgery. An observational study of 114 patients treated for cervical cancer at the "La Fe" Maternity Hospital in Valencia (Spain) during the period 1971 to 1989. Survival analyses...

    journal_title:Archives of gynecology and obstetrics

    pub_type: 杂志文章


    authors: Martin-Loeches M,Ortí RM,Asins E,Llixiona J

    更新日期:2003-01-01 00:00:00

  • [Intratubal gamete transfer].

    abstract::Three years' experience with gamete intrafallopian transfer (GIFT) are reported. Between June 1985 and July 1988, 173 clinical pregnancies were achieved in 357 patients over 488 cycles; 34 biochemical pregnancies achieved have not been included. There were 44 spontaneous abortions (25.4%) and 13 ectopic pregnancies (7...

    journal_title:Archives of gynecology and obstetrics

    pub_type: 杂志文章


    authors: Hepp H,Wiedemann R,Noss H

    更新日期:1989-01-01 00:00:00

  • Sonographic evaluation of kidney parenchymal growth in the fetus.

    abstract:OBJECTIVE:The aim of the study was to establish a nomogram for renal parenchymal thickness throughout pregnancy. METHODS:One-hundred and twenty-eight healthy women with singleton, well-dated, uncomplicated second- or third-trimester pregnancies were prospectively evaluated for renal parenchymal thickness on routine ul...

    journal_title:Archives of gynecology and obstetrics

    pub_type: 杂志文章


    authors: Hadar E,Davidovits M,Mashiach R,Vardimon D,Bardin R,Efrat Z,Danon D,Roth S,Meizner I

    更新日期:2012-10-01 00:00:00

  • Laparoscopic pectopexy: a follow-up cyclic biomechanical analysis determining time to functional stability.

    abstract:INTRODUCTION:Pectopexy, a laparoscopic method for prolapse surgery, showed promising results in previous transient testing by this group. It was shown that a single suture, yielding an ultimate load of 35 N, was equivalent to continuous suturing. This was demonstrated in an in vitro cadaver study. This transient data w...

    journal_title:Archives of gynecology and obstetrics

    pub_type: 杂志文章


    authors: Sauerwald A,Langer L,Ratiu D,Prescher A,Scaal M,Noé GK,Wegmann K,Bulian DR,Eichler C

    更新日期:2019-05-01 00:00:00

  • Giant oocytes in human in vitro fertilization treatments.

    abstract:PURPOSE:Giant oocytes are potential sources of chromosomal abnormalities and should thus never be used in in vitro fertilization and embryo transfer (IVF-ET) procedures. The presence of giant oocytes may indicate the efficiency of the ovarian stimulation and can refer to the quality of sibling oocytes. METHODS:IVF cyc...

    journal_title:Archives of gynecology and obstetrics

    pub_type: 杂志文章


    authors: Lehner A,Kaszas Z,Murber A,Rigo J Jr,Urbancsek J,Fancsovits P

    更新日期:2015-09-01 00:00:00

  • The use of intravenous magnesium in non-preeclamptic pregnant women: fetal/neonatal neuroprotection.

    abstract:PURPOSE:To review the effect of intravenous magnesium in obstetrics on fetal/neonatal neuroprotection. METHODS:A systematic review of published studies. RESULTS:Five randomized trials and 4 meta-analyses have shown a significant 32% reduction of cerebral palsy when administering magnesium sulfate in case of preterm d...

    journal_title:Archives of gynecology and obstetrics

    pub_type: 杂志文章,评审


    authors: Jacquemyn Y,Zecic A,Van Laere D,Roelens K

    更新日期:2015-05-01 00:00:00

  • Prevalence of anxiety symptoms and depression in the third gestational trimester.

    abstract:OBJECTIVE:To determine the prevalence of anxiety and gestational depression and to determine the risk factors associated to its development. METHOD:Pregnant women during their third quarter of pregnancy were invited to participate to the study, and they signed an informed consent form. After that, they filled in a gen...

    journal_title:Archives of gynecology and obstetrics

    pub_type: 杂志文章


    authors: Ferreira CR,Orsini MC,Vieira CR,do Amarante Paffaro AM,Silva RR

    更新日期:2015-05-01 00:00:00

  • Trial of labor after previous single cesarean delivery in grand-multiparous women: a retrospective cohort study.

    abstract:PURPOSE:To compare pregnancy outcomes in grand-multiparous (GMP) women with and without one previous cesarean delivery (CD), and to evaluate the number of previous successful vaginal deliveries after a CD needed to reduce the complication rate of trials of labor after a previous CD. METHODS:This is a retrospective coh...

    journal_title:Archives of gynecology and obstetrics

    pub_type: 杂志文章


    authors: Ram M,Hiersch L,Ashwal E,Yogev Y,Aviram A

    更新日期:2021-01-03 00:00:00

  • MicroRNA-455-5p exerts inhibitory effect in cervical carcinoma through targeting S1PR1 and blocking mTOR pathway.

    abstract:BACKGROUND:MicroRNAs (miRNAs) have been increasingly exploited in human malignancies. The regulation of microRNA-455-5p (miR-455-5p) has been shown in several cancers, except for cervical carcinoma. Therefore, the role of miR-455-5p was exploited in cervical carcinoma. METHODS:The qRT-PCR experiment was used to assess...

    journal_title:Archives of gynecology and obstetrics

    pub_type: 杂志文章


    authors: Hu D,Sun S,Wang Y

    更新日期:2020-05-01 00:00:00

  • [New progestins in oral hormonal contraceptives].

    abstract::Three new progestins with a high gestagenic potency have been developed as derivatives of the levonorgestrel (in brackets: biological active substance in the human): desogestrel (3-keto-desogestrel), norgestimate (norgestimate), gestodene (gestodene). In combination with low dosages of ethinylestradiol (30-35 microgra...

    journal_title:Archives of gynecology and obstetrics

    pub_type: 杂志文章,评审


    authors: Runnebaum B,Rabe T

    更新日期:1989-01-01 00:00:00

  • Cancer associated serum antigen (CASA) levels in patients with breast carcinoma and in 3 control groups without breast cancer.

    abstract::We have examined the predictive value of measurements of CASA (Cancer Associated Serum Antigen) levels in patients with breast carcinoma. The measurement uses monoclonal antibodies that bind to an epitope on the polymorphic epithelial mucin. CASA levels were of less value compared with the levels of other tumor marker...

    journal_title:Archives of gynecology and obstetrics

    pub_type: 杂志文章


    authors: Meisel M,Weise J,Schwesinger G,Straube W

    更新日期:1998-01-01 00:00:00

  • Detection of tumor cells in leukapheresis products from patients with breast cancer using immunocytochemical staining method.

    abstract::We used a combination of 4 monoclonal antibodies (BM7, BM8 against MUC1, 5D3 against CK8,18,19 and HEA125 against human epithelial antigen) and a sensitive immunocytochemical staining using cytospin preparation to identify breast tumor cells in leukapheresis products (LP). This assay allowed detection of one tumor cel...

    journal_title:Archives of gynecology and obstetrics

    pub_type: 杂志文章


    authors: Lin YS,Zhong XY,Hohaus S,Kaul S,Haas R

    更新日期:2000-02-01 00:00:00

  • Complication and recurrence rate in laser CO2 versus traditional surgery in the treatment of Bartholin's gland cyst.

    abstract:PURPOSE:The treatment of Bartholin's gland cysts by traditional surgery is characterized by some disadvantages and complications such as hemorrhage, postoperative dyspareunia, infections, necessity for a general anesthesia. Contrarily, CO2 laser surgery might be less invasive and more effective as it solves many proble...

    journal_title:Archives of gynecology and obstetrics

    pub_type: 杂志文章


    authors: Frega A,Schimberni M,Ralli E,Verrone A,Manzara F,Schimberni M,Nobili F,Caserta D

    更新日期:2016-08-01 00:00:00

  • Efficacy of transcutaneous electrical nerve stimulation for pain relief in women undergoing office endometrial biopsy.

    abstract:AIM:To evaluate the efficacy of transcutaneous electrical nerve stimulation (TENS) for decreasing pain related with office endometrial biopsy. METHODS:In this prospective study, 65 women undergoing office endometrial biopsy were randomly allocated to receive 550 mg oral naproxen sodium plus active TENS (Group I, n = 3...

    journal_title:Archives of gynecology and obstetrics

    pub_type: 杂志文章,随机对照试验


    authors: Yilmazer M,Kose S,Arioz DT,Koken G,Ozbulut O

    更新日期:2012-04-01 00:00:00

  • Postabortal haemorrhage and disseminated intravascular coagulation due to placenta accreta.

    abstract::We describe the case of a second trimester placenta accreta presenting as postabortal haemorrhage complicated by disseminated intravascular coagulation, requiring hysterectomy. ...

    journal_title:Archives of gynecology and obstetrics

    pub_type: 杂志文章


    authors: Lapresta Moros M,Conte Martín P,Pérez Pérez P,Azúa Romeo J,Oro Fraile J,Lapresta Ferrández C

    更新日期:2003-10-01 00:00:00

  • Deep endometriosis inflicting the bladder: long-term outcomes of surgical management.

    abstract:OBJECTIVE:To assess the efficacy and safety of laparoscopic treatment of bladder endometriosis, especially in cases of full thickness endometriotic nodules. DESIGN:Retrospective review of medical records. SETTING:Tertiary medical center and a referral center for endometriosis. POPULATION:Sixty-nine patients with bla...

    journal_title:Archives of gynecology and obstetrics

    pub_type: 杂志文章


    authors: Schonman R,Dotan Z,Weintraub AY,Bibi G,Eisenberg VH,Seidman DS,Goldenberg M,Soriano D

    更新日期:2013-12-01 00:00:00

  • Spontaneous delivery is related to barometric pressure.

    abstract:BACKGROUND:Many studies have shown that changes in the weather affect health. In the field of obstetrics and gynecology, several events have been empirically shown to be related to the weather. Labor pain is controlled by the autonomic nervous system and various hormones, and is expected to be influenced by the weather...

    journal_title:Archives of gynecology and obstetrics

    pub_type: 杂志文章


    authors: Akutagawa O,Nishi H,Isaka K

    更新日期:2007-04-01 00:00:00

  • Pseudo-Meig's syndrome with multiple synchronous benign and malignant pelvic tumors.

    abstract:BACKGROUND:Meig's and Pseudo-Meig's syndromes have been reported in association with several malignancies but the concomitant existence of multiple synchronous benign and malignant tumors in association with Pseudo-Meigs' syndrome has not been reported in the published literature. CASE:A 55-year old African American w...

    journal_title:Archives of gynecology and obstetrics

    pub_type: 杂志文章


    authors: Junaid I,Paz R,Salihu HM,Sharma PP,Aliyu ZY

    更新日期:2006-02-01 00:00:00

  • Relationship between first trimester visualization of the intracranial translucency and spina bifida.

    abstract:PURPOSE:To establish a reference range for the intracranial translucency (IT). METHODS:In this prospective study, we examined 596 singleton fetuses at 11-14 weeks of gestation using transabdominal ultrasonography. The distribution curves of the anterior-posterior diameter of the IT were established according to the ge...

    journal_title:Archives of gynecology and obstetrics

    pub_type: 杂志文章


    authors: Yuksel MA,Arisoy R,Erdogdu E,Imamoglu M,Yayla M,Sen C

    更新日期:2015-03-01 00:00:00

  • A study of the value of measuring maternal serum alpha-fetoprotein for the antenatal diagnosis of neural tube defects.

    abstract::Two neighbouring centres, both located in an area where the prevalence of neural tube defects (NTDs) is low, were compared to determine if there was any advantage in their differing policies as regards the antenatal detection of NTDs. At both centres routine ultrasound examinations were performed at 16-18 weeks gestat...

    journal_title:Archives of gynecology and obstetrics

    pub_type: 杂志文章


    authors: Tidy J

    更新日期:1989-01-01 00:00:00

  • Metabolic changes in follicular fluids of patients treated with recombinant versus urinary human chorionic gonadotropin for triggering ovulation in assisted reproductive technologies: a metabolomics pilot study.

    abstract:INTRODUCTION:The main goal of this retrospective cohort study is the assessment of the effects of administration of recombinant-hCG (r-hCG) versus urinary-hCG (u-hCG) on follicular fluid (FF) composition of women who underwent in vitro fertilization (IVF) treatments. MATERIALS AND METHODS:We selected 70 patients with ...

    journal_title:Archives of gynecology and obstetrics

    pub_type: 杂志文章


    authors: Castiglione Morelli MA,Iuliano A,Schettini SCA,Petruzzi D,Ferri A,Colucci P,Viggiani L,Ostuni A

    更新日期:2020-09-01 00:00:00

  • Plasma pentraxin 3 is higher in early ovarian hyperstimulation syndrome than in uncomplicated in vitro fertilization cycle of high-risk women.

    abstract:PURPOSE:Pentraxin 3 (PTX3) is a locally secreted, quicker responsive pro-inflammatory protein than C-reactive protein (CRP). We evaluated the value of PTX3 in the prediction of ovarian hyperstimulation syndrome (OHSS), a severe complication of in vitro fertilization (IVF). METHODS:This two-year prospective follow-up s...

    journal_title:Archives of gynecology and obstetrics

    pub_type: 杂志文章


    authors: Korhonen K,Unkila-Kallio L,Alfthan H,Hämäläinen E,Tiitinen A,Mikkola T,Tapanainen J,Savolainen-Peltonen H

    更新日期:2020-06-01 00:00:00