Effective of metronidazole to bacterial flora in vagina and the impact of microbes on live birth rate during intracytoplasmic sperm injection (ICSI).


PURPOSE:The aim of this study was to investigate the impact of bacterial vaginal flora on life-birth rate during ICSI and influence of metronidazole as antibiotic treatment course before ICSI. METHOD:We enrolled 71 women who were undergoing ICSI. At embryo transfer (ET), all of the women had quantitative vaginal culture, ET catheter-tip culture, and vaginal Gram stain scored for bacterial vaginosis. RESULTS:The overall live birth rate (LBR) was 36.6% (26/71), and the rate of early pregnancy loss was 13% (4/30). In women with bacterial vaginosis, intermediate flora and normal flora, the conception rates were 35% (9/26), 42% (14/33) and 58% (7/12), respectively (p = 0.06 for trend). Metronidazole effect to bacterial flora in vaginal. The predominant species isolated from the tip of the embryo transfer catheter in negative pregnancy was Staphylococcus epidermidis (7 vs. 15.2%), and Streptococcus viridians (11 vs. 24%). CONCLUSIONS:Woman with bacterial vaginosis and with a decreased vaginal concentration of hydrogen peroxide-producing lactobacilli may have decreased conception rates and increased rates of failed pregnancy. A larger prospective treatment trial designed to evaluate the impact on ICSI outcomes of optimizing the vaginal flora prior to ICSI may be warranted.


Arch Gynecol Obstet


Selim SA,El Alfy SM,Aziz MH,Mohamed HM,Alasbahi AA




Has Abstract


2011-12-01 00:00:00












  • New trial of progestin-primed ovarian stimulation using dydrogesterone versus a typical GnRH antagonist regimen in assisted reproductive technology.

    abstract:PURPOSE:To compare the clinical and ongoing pregnancy rates between a protocol using oral dydrogesterone with human menopausal gonadotropin (HMG) for progestin-primed ovarian stimulation (PPOS) and the typical gonadotropin-releasing hormone (GnRH) antagonist regimen in women undergoing controlled ovarian hyperstimulati...

    journal_title:Archives of gynecology and obstetrics

    pub_type: 杂志文章


    authors: Iwami N,Kawamata M,Ozawa N,Yamamoto T,Watanabe E,Moriwaka O,Kamiya H

    更新日期:2018-09-01 00:00:00

  • Microwave endometrial ablation for an enlarged uterus.

    abstract:INTRODUCTION:An enlarged uterus of more than 12 cm in cavum length with a distorted cavity is a contra-indication for conventional ablative techniques. It is difficult to perform satisfactory endometrial ablation in a large uterus with submucosal myomas using straight instruments. A new curved microwave applicator 4 mm...

    journal_title:Archives of gynecology and obstetrics

    pub_type: 杂志文章


    authors: Kanaoka Y,Hirai K,Ishiko O

    更新日期:2003-11-01 00:00:00

  • The challenge of preoperative identification of uterine myomas: Is ultrasound trustworthy? A prospective cohort study.

    abstract:PURPOSE:To correlate preoperative ultrasound examination with intraoperative and anatomo-pathological findings, including estimation of number, localization and size of uterine myomas, uterine diameters and volume. METHODS:A prospective study on 126 women undergoing surgery for uterine myomatosis at Campus Bio-medico ...

    journal_title:Archives of gynecology and obstetrics

    pub_type: 杂志文章


    authors: Battista C,Capriglione S,Guzzo F,Luvero D,Sadun B,Cafà EV,Sereni MI,Terranova C,Plotti F,Angioli R

    更新日期:2016-06-01 00:00:00

  • Ehlers Danlos Syndrome Type IV and pregnancy.

    abstract:INTRODUCTION:A case report is presented of a 23-year-old patient who was diagnosed with Ehlers Danlos syndrome (EDS) Type IV (vascular type) in the 23rd week of her second pregnancy. EDS Type IV has one of the highest mortality rates for pregnant women of any condition with significant morbidity if the mother survives....

    journal_title:Archives of gynecology and obstetrics

    pub_type: 杂志文章


    authors: Hammond R,Oligbo N

    更新日期:2012-01-01 00:00:00

  • MarginProbe© reduces the rate of re-excision following breast conserving surgery for breast cancer.

    abstract:PURPOSE:A positive margin status after breast conserving surgery (BCS) is one of the strongest predictors for local recurrence of intraductal (DCIS) and invasive carcinoma. As much as 20-50 % of patients with BCS need to undergo a second operation to receive free margins. In this study we tested the clinical performanc...

    journal_title:Archives of gynecology and obstetrics

    pub_type: 杂志文章


    authors: Blohmer JU,Tanko J,Kueper J,Groß J,Völker R,Machleidt A

    更新日期:2016-08-01 00:00:00

  • Indication of prophylactic vaccines as a tool for secondary prevention in HPV-linked disease.

    abstract:PURPOSE:To determine whether quadrivalent HPV vaccination is effective in reducing recurrent disease in women with a previous history of HPV disease. METHODS:All women under 45 years of age treated for HPV-linked disease and with negative HPV test, cytology and colposcopy 3 months after treatment were enrolled. Women ...

    journal_title:Archives of gynecology and obstetrics

    pub_type: 杂志文章,随机对照试验


    authors: Pieralli A,Bianchi C,Auzzi N,Fallani MG,Bussani C,Fambrini M,Cariti G,Scarselli G,Petraglia F,Ghelardi A

    更新日期:2018-12-01 00:00:00

  • MRP2 (ABCC2, cMOAT) expression in nuclear envelope of primary fallopian tube cancer cells is a new unfavorable prognostic factor.

    abstract:OBJECTIVE:To determine the prognostic value of the immunohistochemical evaluation of the multidrug resistance-associated protein 2 (MRP2) expression, together with its subcellular localization in primary fallopian tube carcinomas (PFTCs). METHODS:The immunohistochemical analysis was performed using samples originating...

    journal_title:Archives of gynecology and obstetrics

    pub_type: 杂志文章


    authors: Halon A,Materna V,Donizy P,Matkowski R,Rabczynski J,Lage H,Surowiak P

    更新日期:2013-03-01 00:00:00

  • Photodynamic therapy for recurrent gynecologic malignancy: a report on 4 cases.

    abstract::4 patients with recurrent gynecological malignancy were treated photodynamically, 4 d after sensitisation with intravenous meso-tetra(hydroxyphenyl)-chlorin (m-THPC) at a dose of 0.15 mg/kg bodyweight (total dose ranged from 12-15 mg). Light at 652 nm was derived from a KTP-Dye laser (Diasonic) and delivered superfici...

    journal_title:Archives of gynecology and obstetrics

    pub_type: 杂志文章


    authors: Krimbacher E,Zeimet AG,Marth C,Kostron H

    更新日期:1999-01-01 00:00:00

  • Survivors of primary breast cancer 5 years after surgery: follow-up care, long-term problems, and treatment regrets. Results of the prospective BRENDA II-study.

    abstract:PURPOSE:This study aims to answer the questions where breast cancer patients in Germany receive follow-up care (with what types of doctors) and what are the long-term problems and treatment regrets of breast cancer patients. METHODS:In the prospective multicenter cohort study BRENDA II ("Breast Cancer under Evidence-B...

    journal_title:Archives of gynecology and obstetrics

    pub_type: 杂志文章,多中心研究


    authors: Leinert E,Kreienberg R,Wöckel A,Kühn T,Flock F,Felberbaum R,Janni W,Taylor K,Singer S,Schwentner L,BRENDA study group.

    更新日期:2020-03-01 00:00:00

  • Colon penetration by a copper intrauterine device: a case report with literature review.

    abstract:AIM:The present case report describes colon injury subsequent to uterine penetration which is associated with the use of an intrauterine device (IUD). CASE:A 29-year-old multiparous woman, who presented with vague abdominal pain, had a TCu 380A inserted at her postpartum third month visit. The T-shaped segment of the ...

    journal_title:Archives of gynecology and obstetrics

    pub_type: 杂志文章


    authors: Arslan A,Kanat-Pektas M,Yesilyurt H,Bilge U

    更新日期:2009-03-01 00:00:00

  • The use of peritoneum for vaginoplasty in 24 patients with congenital absence of the vagina.

    abstract::Vaginoplasty using pelvic peritoneum (Rothman's method) was used in 24 patients with congenital absence of the vagina. The results are presented. Rothman (1972) described vaginoplasty using pelvic peritoneum. We have operated on 24 patients with the anomaly. In this report, the better technique for this operation and ...

    journal_title:Archives of gynecology and obstetrics

    pub_type: 杂志文章


    authors: Tamaya T,Imai A

    更新日期:1991-01-01 00:00:00

  • A short narrative review of the feasibility of adopting mild ovarian stimulation for IVF as the current standard of care.

    abstract:INTRODUCTION:Mild ovarian stimulation has been conceived, proposed and implemented in clinical practice as a safer and cheaper alternative to conventional strategies of controlled ovarian hyperstimulation in preparation for in vitro fertilization (IVF). Our aim was to summarize the key evidence on this topic and explor...

    journal_title:Archives of gynecology and obstetrics

    pub_type: 杂志文章,评审


    authors: Siristatidis C,Trivella M,Chrelias C,Sioulas VD,Vrachnis N,Kassanos D

    更新日期:2012-08-01 00:00:00

  • Cytogenetics of human spermatozoa. The frequency of various chromosome aberrations and their relationship to clinical and biological parameters.

    abstract::Human sperm chromosomes can be visualized after their fusion with zona-free hamster eggs. We analyzed a total of 867 metaphases from 33 men that had been classified into three different groups. We present a detailed summary of the kind and frequency of chromosome aberrations we encountered. A comparison of our results...

    journal_title:Archives of gynecology and obstetrics

    pub_type: 杂志文章


    authors: Rosenbusch B,Sterzik K

    更新日期:1994-01-01 00:00:00

  • Tubal ectopic pregnancy: diagnosis and management.

    abstract::Ectopic pregnancy is the gynaecological emergency par excellence and remains the leading cause of pregnancy-related first trimester deaths in the UK. Its prevalence continues to rise because of increases in the incidence of the risk factors predisposing to ectopic pregnancy. Classically, the diagnosis is based on a hi...

    journal_title:Archives of gynecology and obstetrics

    pub_type: 杂志文章,评审


    authors: Nama V,Manyonda I

    更新日期:2009-04-01 00:00:00

  • Acute abdomen as first symptom of acute leukemia.

    abstract:CASE REPORT:The authors presented a rare case of acute abdomen syndrome caused by the rupture of the corpus rubrum as the first symptom in a 35-years-old woman with the acute lymphatic leukemia. During the laparotomy is notice diffuse bleeding from under skin blood vessels and muscles. The blood was electrocoagulated a...

    journal_title:Archives of gynecology and obstetrics

    pub_type: 杂志文章


    authors: Habek D,Cerkez Habek J,Galić J,Goll-Barić S

    更新日期:2004-09-01 00:00:00

  • Secondary malignant fibrous histiocytoma of thigh with surface ulceration following radiotherapy for carcinoma cervix.

    abstract:INTRODUCTION:Radiotherapy is known to cause rarely various malignancies including leukemia, sarcoma, and thyroid and lung carcinoma. Post-radiation sarcomas account for 0.5-5.5% of all sarcomas; and include extra skeletal osteosarcoma, fibrosarcoma leiomyosarcoma, and malignant fibrous histiocytoma. Reports on post rad...

    journal_title:Archives of gynecology and obstetrics

    pub_type: 杂志文章


    authors: Arora P,Wadhwa R,Khurana N,Jain S,Hadke NS

    更新日期:2011-03-01 00:00:00

  • What happens after randomised controlled trials? Uterine fibroids and ulipristal acetate: systematic review and meta-analysis of "real-world" data.

    abstract:PURPOSE:"Real-world" data incorporates studies performed outside of controlled environments, allowing for a better understanding of the effects of treatment in routine clinical practice. We, therefore, performed a systematic review to summarise available "real-world studies" reporting on the use of ulipristal acetate (...

    journal_title:Archives of gynecology and obstetrics

    pub_type: 杂志文章,评审


    authors: Shah N,Egbase E,Sideris M,Odejinmi F

    更新日期:2021-01-02 00:00:00

  • Single-knot versus multiple-knot technique of perineal repair: a randomised controlled trial.

    abstract:PURPOSE:An important factor influencing the outcome of perineal repair is the repair technique. This study was done to determine if there is a difference in post perineal repair pain scores following the use of the standard multiple-knot technique (MKT) of perineal repair and a single-knot technique (SKT). METHODS:We ...

    journal_title:Archives of gynecology and obstetrics

    pub_type: 杂志文章,随机对照试验


    authors: Selo-Ojeme DO,Okonkwo CA,Atuanya C,Ndukwu K

    更新日期:2016-11-01 00:00:00

  • Opioid use in pregnant women with mental health-related disabilities.

    abstract:PURPOSE:The purpose of this study was to examine associations between opioid use and the degree of mental health-related disability due to emotional/behavioral problems as measured by the World Health Organization Disability Assessment Schedule (WHODAS) instrument in a national sample of pregnant women. METHODS:We use...

    journal_title:Archives of gynecology and obstetrics

    pub_type: 杂志文章


    authors: Kitsantas P,Adams AR,Cheema J,Kornides ML

    更新日期:2021-01-10 00:00:00

  • Color Doppler ultrasound (CDU) in the diagnosis of obstructive hydronephrosis in pregnant women.

    abstract:PURPOSE:Color Doppler ultrasound (CDU) accuracy of kidneys and bladder in the diagnosis and treatment of hydronephrosis and/or renal colic in pregnancies was evaluated. METHODS:Between January 2010 and September 2012, 234 pregnant women asymptomatic in 204 cases and with unilateral renal colic in 30 (median 26 years) ...

    journal_title:Archives of gynecology and obstetrics

    pub_type: 杂志文章


    authors: Pepe F,Pepe P

    更新日期:2013-09-01 00:00:00

  • Evaluation of the contraceptive efficacy, compliance, and satisfaction with the transdermal contraceptive patch system Evra: a comparison between adolescent and adult users.

    abstract:OBJECTIVE:Aim of the study was to evaluate Evra use in adolescents and compare the outcome with adult users. METHODS:A total of 80 adolescents and 178 adults were followed-up at 1-, 3-, and 6-month interval with their compliance, satisfaction, cycle control, and adverse events being assessed. RESULTS:Compliance rate ...

    journal_title:Archives of gynecology and obstetrics

    pub_type: 杂志文章


    authors: Bodner K,Bodner-Adler B,Grünberger W

    更新日期:2011-03-01 00:00:00

  • Effects of aspirin on placenta and perinatal outcomes in patients with poor obstetric history.

    abstract:OBJECTIVE:The aim of this study was to compare a low-dose aspirin treatment on placental and perinatal effects in the patients with poor obstetric history such as preeclampsia, intrauterine growth retardation (IUGR) in previous pregnancy. STUDY DESIGN:This retrospective study of 86 pregnant women was conducted between...

    journal_title:Archives of gynecology and obstetrics

    pub_type: 临床试验,杂志文章


    authors: Tarim E,Bal N,Kilicdag E,Kayaselcuk F,Bağiş T,Kuscu E

    更新日期:2006-07-01 00:00:00

  • Ovarian interstitial blood flow changes assessed by transvaginal colour Doppler sonography: predicting ovarian endometrioid cyst-induced injury to ovarian interstitial vessels.

    abstract:PURPOSE:To evaluate the blood flow changes and their relationships to microvessel density (MVD) and thrombospondin-1 (TSP-1) by transvaginal colour Doppler sonography (TV-CDS) in the ovarian interstitium to predict ovarian interstitial microvascular injury in the pathological process of ovarian endometrial cysts (OEC)....

    journal_title:Archives of gynecology and obstetrics

    pub_type: 杂志文章


    authors: Qiu JJ,Liu YL,Liu MH,Chen LP,Xu DW,Zhang ZX,Yang QC,Liu HB

    更新日期:2012-02-01 00:00:00

  • A CA125 score as a prognostic index in patients with ovarian cancer.

    abstract::Due to its high specificity (90%) and sensitivity (86%) measurement of CA125 has become well-established in patients with epithelial ovarian cancer. We have formulated a CA125 prognostic score and examined its validity as an additional prognosis index. This score is composed of two CA125 values (one determined preoper...

    journal_title:Archives of gynecology and obstetrics

    pub_type: 杂志文章


    authors: Rosen A,Sevelda P,Klein M,Spona J,Beck A

    更新日期:1990-01-01 00:00:00

  • Breast cancer patients' satisfaction with individual therapy goals and treatment in a standardized integrative medicine consultancy service.

    abstract:PURPOSE:Complementary medicine services are nowadays usually quite heterogeneous, and little information is available on standards for running an integrative medicine consultancy service. This study aimed to assess patients' satisfaction with a standardized treatment service on integrative medicine. METHODS:Using a cr...

    journal_title:Archives of gynecology and obstetrics

    pub_type: 杂志文章


    authors: Hack CC,Antoniadis S,Hackl J,Langemann H,Schwitulla J,Fasching PA,Beckmann MW,Theuser AK

    更新日期:2018-07-01 00:00:00

  • The diagnosis and treatment of iatrogenic ureteral and bladder injury caused by traditional gynaecology and obstetrics operation.

    abstract:OBJECTIVE:To explore the etiologic factors and treatments of iatrogenic ureteral and bladder injury during obstetric and gynecologic operations. METHODS:Forty-one patients who underwent traditional obstetric and gynecologic operations were found with iatrogenic ureteral and bladder injury, and recruited into our study...

    journal_title:Archives of gynecology and obstetrics

    pub_type: 杂志文章


    authors: Rao D,Yu H,Zhu H,Duan P

    更新日期:2012-03-01 00:00:00

  • Psychological predictors of gestational outcomes in second trimester pregnant women: associations with daily uplifts.

    abstract:PURPOSE:We investigated whether pregnancy/birth anxiety is associated with shorter gestation while maternal chronic stress and depressive symptoms are associated with lower birth weight; we also examined whether experiencing daily uplifts prenatally may contribute to a more favorable birth outcome. METHODS:Thirty-four...

    journal_title:Archives of gynecology and obstetrics

    pub_type: 新闻


    authors: Amiel Castro RT,Ehlert U,Dainese SM,Zimmerman R,La Marca-Ghaemmaghami P

    更新日期:2020-04-01 00:00:00

  • Robotic assisted vs laparoscopic and/or open myomectomy: systematic review and meta-analysis of the clinical evidence.

    abstract:INTRODUCTION:Uterine myomas are relative frequent in premenopausal women. The development of advanced minimally invasive surgical techniques proposed robotic-assisted myomectomy as an equally safe and effective treatment option. METHODS:PubMed, Scopus and Cochrane databases were systematically searched and 15 studies ...

    journal_title:Archives of gynecology and obstetrics

    pub_type: 杂志文章,meta分析,评审


    authors: Iavazzo C,Mamais I,Gkegkes ID

    更新日期:2016-07-01 00:00:00

  • Altered VEGF, Bcl-2 and IDH1 expression in patients with adenomyosis.

    abstract:PURPOSE:Adenomyosis is a benign uterine disease resulting from the myometrial invasion of the endometrial gland and stroma. In the current study, angiogenesis, apoptosis and energy metabolism were investigated in adenomyosis. METHODS:A retrospective study was performed using paraffin archival tissues. Three groups wer...

    journal_title:Archives of gynecology and obstetrics

    pub_type: 杂志文章


    authors: Yalaza C,Canacankatan N,Gürses İ,Aytan H,Taşdelen B

    更新日期:2020-11-01 00:00:00

  • Predictors of resectability in breast-conserving therapy.

    abstract:BACKGROUND:Our goal is to identify subgroups of women undergoing breast-conserving therapy (BCT) who are at increased risk for requiring a secondary surgical procedure, and to identify tumor and patient profiles that will allow surgeons to anticipate the need for taking larger margins when removing the tumor. METHODS:...

    journal_title:Archives of gynecology and obstetrics

    pub_type: 杂志文章


    authors: Rath MG,Heil J,Domschke C,Topic Z,Schneider S,Sinn HP,Marme F,Scharf A,Schneeweiss A,Sohn C,Rom J

    更新日期:2012-10-01 00:00:00