Identification and characterization of genes encoding sex pheromone cAM373 activity in Enterococcus faecalis and Staphylococcus aureus.

abstract：:Previous studies have shown that in Saccharomyces cerevisiae the mitochondrial and cytoplasmic forms of alanyl-tRNA synthetase are encoded by a single nuclear gene, ALA1, through alternative use of in-frame successive ACG triplets and a downstream AUG triplet. Here we show that despite the obvious participation of the...

journal_title：Molecular microbiology

authors： Huang HY,Tang HL,Chao HY,Yeh LS,Wang CC

更新日期：2006-04-01 00:00:00

abstract：:The NAC (nitrogen assimilation control) protein from Klebsiella aerogenes is a LysR-like regulator for transcription of several operons involved in nitrogen metabolism, and couples the transcription of these sigma 70-dependent operons to regulation by the sigma 54-dependent NTR system. NAC activates expression of oper...

journal_title：Molecular microbiology

authors： Bender RA

更新日期：1991-11-01 00:00:00

abstract：:The ubiquitous human commensal Escherichia coli has been well investigated through its model representative E. coli K-12. In this work, we initially characterized E. coli Fec10, a recently isolated human commensal strain of phylogroup A/sequence type ST10. Compared to E. coli K-12, the 4.88 Mbp Fec10 genome is charact...

journal_title：Molecular microbiology

authors： Kamal SM,Cimdins-Ahne A,Lee C,Li F,Martín-Rodríguez AJ,Seferbekova Z,Afasizhev R,Wami HT,Katikaridis P,Meins L,Lünsdorf H,Dobrindt U,Mogk A,Römling U

更新日期：2020-09-28 00:00:00

abstract：:Of the four Plasmodium species that routinely cause malaria in humans, Plasmodium falciparum is responsible for the majority of malaria mortality and consequently gets most of the headlines. Outside Africa, however, more malaria cases are caused by its distant cousin Plasmodium vivax, resulting in a daunting morbidity...

journal_title：Molecular microbiology

authors： Rayner J

更新日期：2005-03-01 00:00:00

abstract：:The bacteriocin release protein (BRP) mediates the secretion of cloacin DF13. The BRP precursor is slowly processed to yield the mature BRP and its stable signal peptide which is also involved in cloacin DF13 secretion. The function of the stable BRP signal peptide was analysed by constructing two plasmids. First, the...

journal_title：Molecular microbiology

authors： van der Wal FJ,Oudega B,Kater MM,ten Hagen-Jongman CM,de Graaf FK,Luirink J

更新日期：1992-08-01 00:00:00

abstract：:Bacillus subtilis responds to signals of environmental and metabolic stress by inducing over 40 general stress genes under the control of the sigma B transcription factor. sigma B activity is regulated post-translationally by a multi-component network composed of two coupled partner-switching modules, RsbX-RsbS-RsbT a...

journal_title：Molecular microbiology

authors： Akbar S,Kang CM,Gaidenko TA,Price CW

更新日期：1997-05-01 00:00:00

abstract：:Pseudomonas aeruginosa can express two distinct forms of lipopolysaccharide (LPS), called A-band and B-band. As an attempt to understand the molecular biology of the synthesis and regulation of these LPS antigens, a recombinant plasmid, pFV3, containing genes for A-band expression was isolated previously. In the prese...

journal_title：Molecular microbiology

authors： Lightfoot J,Lam JS

更新日期：1993-05-01 00:00:00

abstract：:The Bacillus subtilis genome encodes three apparent lipoyl ligase homologues: yhfJ, yqhM and ywfL, which we have renamed lplJ, lipM and lipL respectively. We show that LplJ encodes the sole lipoyl ligase of this bacterium. Physiological and biochemical characterization of a ΔlipM strain showed that LipM is absolutely ...

journal_title：Molecular microbiology

authors： Martin N,Christensen QH,Mansilla MC,Cronan JE,de Mendoza D

更新日期：2011-04-01 00:00:00

abstract：:The bacterium Burkholderia glumae causes rice grain rot by producing toxoflavin, whose expression is regulated by quorum sensing (QS). We report a major deviation from the current paradigm for the regulation of bacterial polar flagellum genes. The N-octanoyl homoserine lactone (C8-HSL)-deficient mutant of B. glumae is...

journal_title：Molecular microbiology

authors： Kim J,Kang Y,Choi O,Jeong Y,Jeong JE,Lim JY,Kim M,Moon JS,Suga H,Hwang I

更新日期：2007-04-01 00:00:00

abstract：:The ctaD gene encoding subunit I of the aa3-type cytochrome c oxidase from Rhodobacter sphaeroides has been cloned. The gene encodes a polypeptide of 565 residues which is highly homologous to the sequences of subunit I from other prokaryotic and eukaryotic sources, e.g. 51% identity with that from bovine, and 75% ide...

journal_title：Molecular microbiology

authors： Shapleigh JP,Gennis RB

更新日期：1992-03-01 00:00:00

abstract：:The Escherichia coli rpsD12 allele, which reduces translational fidelity and elevates expression of heat shock protein (Hsp) genes, only enhanced Hsp gene expression in the presence of oxygen. Similarly, the rpsL141 allele, which reduces mistranslation and Hsp gene expression, failed to affect the Hsp regulon in cells...

journal_title：Molecular microbiology

authors： Fredriksson A,Ballesteros M,Dukan S,Nyström T

更新日期：2006-01-01 00:00:00

abstract：:Long-term antibiotic treatment offers a rare opportunity to study the evolution of bacteria within the same individual. The appearance of new variants has been suggested to take place via the selection of enhanced resistance in compartments of the body in which the antibiotic concentration is low. Laboratory models of...

journal_title：Molecular microbiology

authors： Low AS,MacKenzie FM,Gould IM,Booth IR

更新日期：2001-11-01 00:00:00

abstract：:Rhamnolipid acts as a virulence factor during Pseudomonas aeruginosa infection. Here, we show that deletion of the catabolite repression control (crc) gene in P. aeruginosa leads to a rhamnolipid-negative phenotype. This effect is mediated by the down-regulation of rhl quorum sensing (QS). We discover that a disruptio...

journal_title：Molecular microbiology

authors： Yang N,Ding S,Chen F,Zhang X,Xia Y,Di H,Cao Q,Deng X,Wu M,Wong CC,Tian XX,Yang CG,Zhao J,Lan L

更新日期：2015-05-01 00:00:00

abstract：:Integrative and conjugative elements (ICEs), a.k.a. conjugative transposons, are mobile genetic elements involved in many biological processes, including pathogenesis, symbiosis and the spread of antibiotic resistance. Unlike conjugative plasmids that are extra-chromosomal and replicate autonomously, ICEs are integrat...

journal_title：Molecular microbiology

authors： Lee CA,Babic A,Grossman AD

更新日期：2010-01-01 00:00:00

abstract：:The recent emergence of indolent and rapidly fatal drug-resistant strains of Mycobacterium tuberculosis has renewed interest in defining the molecular mechanisms of drug resistance in the tubercle bacilli. In this report, we have examined the mechanism of resistance to streptomycin (Sm) in M. tuberculosis through the ...

journal_title：Molecular microbiology

authors： Nair J,Rouse DA,Bai GH,Morris SL

更新日期：1993-11-01 00:00:00

abstract：:PilO of Pseudomonas aeruginosa 1244 catalyses the attachment of an O-antigen repeating unit to the beta-carbon of the pilin C-terminal residue, a serine. The present study was conducted to locate the regions of this enzyme important in catalysis and to establish the cellular location of the pilin glycosylation reactio...

journal_title：Molecular microbiology

authors： Qutyan M,Paliotti M,Castric P

更新日期：2007-12-01 00:00:00

abstract：:In Salmonella enterica, an activated Rcs signalling system inhibits initiation of transcription of the flhD master operon. Under these conditions, where motility is shut down, microarray experiments showed an increased RNA signal for three flagellar genes -fliPQR- located upstream of rcsA. We show here that it is the ...

journal_title：Molecular microbiology

authors： Wang Q,Harshey RM

更新日期：2009-10-01 00:00:00

abstract：:MsDef1 and MtDef4 from Medicago spp. are small cysteine-rich defensins with potent antifungal activity against a broad range of filamentous fungi. Each defensin has a hallmark γ-core motif (GXCX(3-9) C), which contains major determinants of its antifungal activity. In this study, the antifungal activities of MsDef1, M...

journal_title：Molecular microbiology

authors： Muñoz A,Chu M,Marris PI,Sagaram US,Kaur J,Shah DM,Read ND

更新日期：2014-06-01 00:00:00

abstract：:We have cloned a gene encoding a polygalacturonase (PG) in the filamentous fungus Aspergillus niger RH5344. The structural gene comprises 1141 bp coding for 362 amino acids and the open reading frame is disrupted by one intron of 52 bp. Eukaryotic consensus sequences for transcription regulation are found only in devi...

journal_title：Molecular microbiology

authors： Ruttkowski E,Khanh NQ,Wientjes FJ,Gottschalk M

更新日期：1991-06-01 00:00:00

abstract：:Transposon insertion mutagenesis and transformation were used to locate genes responsible for excision in the temperature phage HP1 of Haemophilus influenzae. A 6.5 kb segment of DNA near the left end of the phage genome was sequenced, and 11 new open reading frames were identified. Two face-to-face overlapping promot...

journal_title：Molecular microbiology

authors： Esposito D,Scocca JJ

更新日期：1994-08-01 00:00:00

abstract：:Helicobacter pylori strains isolated from most patients with peptic ulcer disease and adenocarcinoma express the vacuolating toxin VacA and contain a pathogenicity island named cag. The cag pathogenicity island codes for more than 40 putative proteins with features similar to bacterial secretion systems. One of these ...

journal_title：Molecular microbiology

authors： Spohn G,Beier D,Rappuoli R,Scarlato V

更新日期：1997-10-01 00:00:00

abstract：:The surface-located fibrinogen-binding protein (clumping factor; ClfA) of Staphylococcus aureus has an unusual dipeptide repeat linking the ligand binding domain to the wall-anchored region. Southern blotting experiments revealed several other loci in the S. aureus Newman genome that hybridized to a probe comprising D...

journal_title：Molecular microbiology

authors： Ní Eidhin D,Perkins S,Francois P,Vaudaux P,Höök M,Foster TJ

更新日期：1998-10-01 00:00:00

abstract：:Genetic exchange by natural transformation in Streptococcus pneumoniae occurs in a cell-density dependent process and is initiated by a small extracellular signalling molecule, the competence-stimulating peptide (CSP). comC, the gene for this peptide, has previously been identified and encodes a 44 amino acid pre-pept...

journal_title：Molecular microbiology

authors： Cheng Q,Campbell EA,Naughton AM,Johnson S,Masure HR

更新日期：1997-02-01 00:00:00

abstract：:The 29 kDa protein of pathogenic Entamoeba histolytica is a cysteine-rich surface antigen which we recently characterized by cDNA sequencing and by using monoclonal antibodies which differentiated between pathogenic and non-pathogenic clinical isolates. To determine the structure and biochemical attributes of this pro...

journal_title：Molecular microbiology

authors： Flores BM,Batzer MA,Stein MA,Petersen C,Diedrich DL,Torian BE

更新日期：1993-03-01 00:00:00

abstract：:We have identified and characterized three genes, SUT1, SUT2 and SUT3, that encode glucose transporters of the yeast Pichia stipitis. When expressed in a Saccharomyces cerevisiae hxt null mutant strain that is unable to take up monosaccharides, all three proteins restored growth on glucose. Sequencing of the genes rev...

journal_title：Molecular microbiology

authors： Weierstall T,Hollenberg CP,Boles E

更新日期：1999-02-01 00:00:00

abstract：:Among players in neurobiology, ion channels are the demigods that underlie all our senses, behaviour and intelligence. In animals, these 'gated pores' detect ligands, voltage, heat or stretch forces and emit electric or ionic signals. Patch clamp and genome sequencing now show that nearly all microbes also have these ...

journal_title：Molecular microbiology

authors： Kung C,Blount P

更新日期：2004-07-01 00:00:00

abstract：:The AppA protein of Rhodobacter sphaeroides is unique in its ability to sense and transmit redox signals as well as light signals. By functioning as antagonist to the PpsR transcriptional repressor, it regulates the expression of photosynthesis genes in response to these environmental stimuli. Here we show binding of ...

journal_title：Molecular microbiology

authors： Han Y,Meyer MH,Keusgen M,Klug G

更新日期：2007-05-01 00:00:00

abstract：:Cytochrome c biogenesis describes the posttranslational pathway for the conversion of pre-apocytochrome c into the mature holocytochrome c. It involves an unknown number of consecutive biochemical steps, including translocation of the precursor polypeptide and haem into the periplasm and the covalent linkage between t...

journal_title：Molecular microbiology

authors： Thöny-Meyer L,Ritz D,Hennecke H

更新日期：1994-04-01 00:00:00

abstract：:Pseudomonas syringae pv. tomato (Pst) strain DC3000 infects the model plants Arabidopsis thaliana and tomato, causing disease symptoms characterized by necrotic lesions surrounded by chlorosis. One mechanism used by Pst DC3000 to infect host plants is the type III protein secretion system, which is thought to deliver ...

journal_title：Molecular microbiology

authors： Zwiesler-Vollick J,Plovanich-Jones AE,Nomura K,Bandyopadhyay S,Joardar V,Kunkel BN,He SY

更新日期：2002-09-01 00:00:00

abstract：:The enteric gamma-proteobacterium Photorhabdus luminescens kills a wide range of insects, whilst also maintaining a mutualistic relationship with soil nematodes from the family Heterorhabditis. Pathogenicity is associated with bacterial exponential growth, whilst mutualism is associated with post-exponential (stationa...

journal_title：Molecular microbiology

authors： Bager R,Roghanian M,Gerdes K,Clarke DJ

更新日期：2016-05-01 00:00:00