Light and oxygen effects share a common regulatory DNA sequence in Rhodobacter capsulatus.

abstract：:Multidrug resistant (MDR) strains of Acinetobacter baumannii present a serious clinical challenge. The development of antibiotic resistance in this species is enabled by efflux pumps of the Resistance-Nodulation-Division (RND) superfamily of proteins creating an efficient permeability barrier for antibiotics. At least...

journal_title：Molecular microbiology

authors： Leus IV,Adamiak J,Trinh AN,Smith RD,Smith L,Richardson S,Ernst RK,Zgurskaya HI

更新日期：2020-12-01 00:00:00

abstract：:Effector translocation is central to the virulence of many bacterial pathogens, including Streptococcus pyogenes, which utilizes the cholesterol-dependent cytolysin Streptolysin O (SLO) to translocate the NAD(+) glycohydrolase SPN into host cells during infection. SLO's translocation activity does not require host cel...

journal_title：Molecular microbiology

authors： Mozola CC,Caparon MG

更新日期：2015-09-01 00:00:00

abstract：:Almost all bacterial genomes contain DNA of viral origin, including functional prophages or degenerated phage elements. A frequent but often unnoted phenomenon is the spontaneous induction of prophage elements (SPI) even in the absence of an external stimulus. In this study, we have analyzed SPI of the large, degenera...

journal_title：Molecular microbiology

authors： Helfrich S,Pfeifer E,Krämer C,Sachs CC,Wiechert W,Kohlheyer D,Nöh K,Frunzke J

更新日期：2015-11-01 00:00:00

abstract：:In addition to being the major citric acid cycle aconitase in Escherichia coli the aconitase B protein (AcnB) is also a post-transcriptional regulator of gene expression. The AcnB proteins represent a distinct branch of the aconitase superfamily that possess a HEAT-like domain (domain 5). The HEAT domains of other pro...

journal_title：Molecular microbiology

authors： Tang Y,Guest JR,Artymiuk PJ,Green J

更新日期：2005-06-01 00:00:00

abstract：:The dominant, polA1-independent replicon of pGSH500, rep beta (1.8 kb), consists of a cis-acting oriV region of 245 bp; a repB gene that is essential for autonomous replication and 18, 30 to 36 bp iterons which constitute the inc/cop region. The molecular organization of rep beta resembles that of mini-pCU1 (IncN). Fu...

journal_title：Molecular microbiology

authors： da Silva-Tatley FM,Steyn LM

更新日期：1993-03-01 00:00:00

abstract：:A screen for Mycobacterium tuberculosis (Mtb) mutants sensitive to reactive nitrogen intermediates identified transposon insertions in the presumptive proteasomal ATPase gene mpa (mycobacterium proteasome ATPase; Rv2115c). mpa mutants are attenuated in both wild type and nitric oxide synthase 2 deficient mice. In this...

journal_title：Molecular microbiology

authors： Darwin KH,Lin G,Chen Z,Li H,Nathan CF

更新日期：2005-01-01 00:00:00

abstract：:Arsenic is the most ubiquitous environmental toxin. Here, we demonstrate that bacteria have evolved the ability to use arsenic to gain a competitive advantage over other bacteria at least twice. Microbes generate toxic methylarsenite (MAs(III)) by methylation of arsenite (As(III)) or reduction of methylarsenate (MAs(V...

journal_title：Molecular microbiology

authors： Chen J,Yoshinaga M,Rosen BP

更新日期：2019-02-01 00:00:00

abstract：:Crown gall tumorigenesis by Agrobacterium tumefaciens requires the co-ordinate transcriptional induction of a set of pathogenesis genes. At least three classes of environmental stimuli act synergistically to induce these genes: (i) monocyclic aromatic hydrocarbons such as acetosyringone, coniferyl alcohol, and vanilli...

journal_title：Molecular microbiology

authors： Winans SC

更新日期：1991-10-01 00:00:00

abstract：:We used the LacO/GFP-LacI system to label and visualize the IncP beta plasmid R751 fluorescently during conjugative transfer between live donor and recipient bacteria. Comparisons of R751 in conjugative and non-conjugative conditions have allowed us to identify key localizations and movements associated with the initi...

journal_title：Molecular microbiology

authors： Lawley TD,Gordon GS,Wright A,Taylor DE

更新日期：2002-05-01 00:00:00

abstract：:Functional ribosomal RNAs are generated from longer precursor species in every organism known. Maturation of the 5' side of 16S rRNA in Escherichia coli is catalysed in a two-step process by the cooperative action of RNase E and RNase G. However, many bacteria lack RNase E and RNase G orthologues, raising the question...

journal_title：Molecular microbiology

authors： Britton RA,Wen T,Schaefer L,Pellegrini O,Uicker WC,Mathy N,Tobin C,Daou R,Szyk J,Condon C

更新日期：2007-01-01 00:00:00

abstract：:The PhaF is a nucleoid-associated like protein of Pseudomonas putida KT2442 involved in the polyhydroxyalkanoate (PHA) metabolism. Its primary structure shows two modular domains; the N-terminal PHA granule-binding domain (phasin domain) and the C-terminal half containing AAKP-like tandem repeats characteristic of the...

journal_title：Molecular microbiology

authors： Galán B,Dinjaski N,Maestro B,de Eugenio LI,Escapa IF,Sanz JM,García JL,Prieto MA

更新日期：2011-01-01 00:00:00

abstract：:Lipochitin Nod signals are produced by rhizobia and are required for the establishment of a nitrogen-fixing symbiosis with a legume host. The nodulation genes encode products required for the synthesis of this signal and are induced in response to plant-produced flavonoid compounds. The addition of chitin and lipo-chi...

journal_title：Molecular microbiology

authors： Loh JT,Stacey G

更新日期：2001-09-01 00:00:00

abstract：:Mutation of staphylococcal accessory regulator (sarA) results in increased production of extracellular proteases in Staphylococcus aureus, which has been correlated with decreased biofilm formation and decreased accumulation of extracellular toxins. We used murine models of implant-associated biofilm infection and S. ...

journal_title：Molecular microbiology

authors： Zielinska AK,Beenken KE,Mrak LN,Spencer HJ,Post GR,Skinner RA,Tackett AJ,Horswill AR,Smeltzer MS

更新日期：2012-12-01 00:00:00

abstract：:Colonies of strains carrying a stable lambdaplacMu15 translational fusion displayed sharply defined intense staining at the centre on Xgal medium. The fusion was in fiu (ferric ion uptake), encoding an iron-regulated outer membrane protein (IROMP) controlled via four overlapping ferric uptake regulator (Fur) boxes in ...

journal_title：Molecular microbiology

authors： Newman DL,Shapiro JA

更新日期：1999-07-01 00:00:00

abstract：:Rhamnolipid acts as a virulence factor during Pseudomonas aeruginosa infection. Here, we show that deletion of the catabolite repression control (crc) gene in P. aeruginosa leads to a rhamnolipid-negative phenotype. This effect is mediated by the down-regulation of rhl quorum sensing (QS). We discover that a disruptio...

journal_title：Molecular microbiology

authors： Yang N,Ding S,Chen F,Zhang X,Xia Y,Di H,Cao Q,Deng X,Wu M,Wong CC,Tian XX,Yang CG,Zhao J,Lan L

更新日期：2015-05-01 00:00:00

abstract：:A biochemical approach to identify proteins with high affinity for choline-containing pneumococcal cell walls has allowed the localization, cloning and sequencing of a gene (lytC ) coding for a protein that degrades the cell walls of Streptococcus pneumoniae. The lytC gene is 1506 bp long and encodes a protein (LytC) ...

journal_title：Molecular microbiology

authors： García P,Paz González M,García E,García JL,López R

更新日期：1999-07-01 00:00:00

abstract：:Helicobacter pylori is anomalous among non nitrogen-fixing bacteria in containing an incomplete NIF system for Fe-S cluster assembly comprising two essential proteins, NifS (cysteine desulfurase) and NifU (scaffold protein). Although nifU deletion strains cannot be obtained via the conventional gene replacement, a Nif...

journal_title：Molecular microbiology

authors： Benoit SL,Holland AA,Johnson MK,Maier RJ

更新日期：2018-05-01 00:00:00

abstract：:We have found a simple relationship between bacterial growth rate and the translation elongation rate. Thus, for a set of defined ribosomal protein S12 mutations which reduce the efficiency of the ternary complex ribosome interaction (and restrict the frequency of translational errors) there is a linear relationship b...

journal_title：Molecular microbiology

authors： Tubulekas I,Hughes D

更新日期：1993-01-01 00:00:00

abstract：:In the chemotaxis of Escherichia coli, adaptation requires the methylation and demethylation of transmembrane receptors, which are catalysed by the methyltransferase CheR and the methylesterase CheB respectively. CheR binds to major chemoreceptors through their C-terminal motif NWETF, which is distinct from the methyl...

journal_title：Molecular microbiology

authors： Shiomi D,Okumura H,Homma M,Kawagishi I

更新日期：2000-04-01 00:00:00

abstract：:The spoIIIG gene encodes a sigma factor that determines prespore-specific gene expression during sporulation in Bacillus subtilis. Correct spatial and temporal expression of the spoIIIG gene depends on a number of other sporulation (spo) genes, but only one of these genes, spoIIIE, has a specific effect on spoIIIG exp...

journal_title：Molecular microbiology

authors： Foulger D,Errington J

更新日期：1989-09-01 00:00:00

abstract：:A method called Muprinting has been developed that uses PCR to generate a detailed picture of the bacteriophage Mu transposition sites in chosen domains of the bacterial chromosome. Muprinting experiments in Escherichia coli show that the frequency of phage integration changes dramatically near two repressor binding s...

journal_title：Molecular microbiology

authors： Wang X,Higgins NP

更新日期：1994-05-01 00:00:00

abstract：:Listeria monocytogenes is a Gram-positive intracellular bacterium responsible for severe opportunistic infections in humans and animals. Signature-tagged mutagenesis (STM) was used to identify a gene named fbpA, required for efficient liver colonization of mice inoculated intravenously. FbpA was also shown to be requi...

journal_title：Molecular microbiology

authors： Dramsi S,Bourdichon F,Cabanes D,Lecuit M,Fsihi H,Cossart P

更新日期：2004-07-01 00:00:00

abstract：:Borrelia hermsii, an agent of relapsing fever, avoids the host's immune response by means of multiphasic antigenic variation. Serotype specificity is determined by variable antigens called the Vmp lipoproteins. Through recombination between linear plasmids a formerly silent vmp gene replaces another vmp gene at a telo...

journal_title：Molecular microbiology

authors： Barbour AG,Burman N,Carter CJ,Kitten T,Bergström S

更新日期：1991-02-01 00:00:00

abstract：:Mutants (glk) of Streptomyces coelicolor A3(2) that are resistant to the non-utilizable glucose analogue 2-deoxyglucose are deficient in glucose kinase activity, defective in glucose repression, and usually unable to utilize glucose. A 2.9 kb BclI fragment, previously shown to restore a wild-type phenotype to a glk de...

journal_title：Molecular microbiology

authors： Angell S,Schwarz E,Bibb MJ

更新日期：1992-10-01 00:00:00

abstract：:In this work we present the localization and characterization of the repl promoter (Prepl) and show aspects of the regulation. Comparison of Prepl with other autoregulated replication protein gene promoters revealed similarities, but Prepl differs from some of these characterized promoters in not being regulated by th...

journal_title：Molecular microbiology

authors： Gammie AE,Crosa JH

更新日期：1991-12-01 00:00:00

abstract：:Certain endospore-forming soil dwelling bacteria are important human, animal or insect pathogens. These organisms produce spores containing an outer layer, the exosporium. The exosporium is the site of interactions between the spore and the soil environment and between the spore and the infected host during the initia...

journal_title：Molecular microbiology

authors： Stewart GC

更新日期：2017-05-01 00:00:00

abstract：:Definitive identification of Treponema pallidum rare outer membrane proteins (OMPs) has long eluded researchers. TP0326, the sole protein in T. pallidum with sequence homology to a Gram-negative OMP, belongs to the BamA family of proteins essential for OM biogenesis. Structural modelling predicted that five polypeptid...

journal_title：Molecular microbiology

authors： Desrosiers DC,Anand A,Luthra A,Dunham-Ems SM,LeDoyt M,Cummings MA,Eshghi A,Cameron CE,Cruz AR,Salazar JC,Caimano MJ,Radolf JD

更新日期：2011-06-01 00:00:00

abstract：:An 18 633 bp region containing the replicon from the approximately 53 kb pBM400 plasmid of Bacillus megaterium QM B1551 has been sequenced and characterized. This region contained a complete rRNA operon plus 10 other potential open reading frames (ORFs). The replicon consisted of an upstream promoter and three contigu...

journal_title：Molecular microbiology

authors： Kunnimalaiyaan M,Stevenson DM,Zhou Y,Vary PS

更新日期：2001-02-01 00:00:00

abstract：:The nucleotide sequence of the proximal half of the rfb region of Shigella flexneri has been determined, and the genes encoding enzymes involved in the biosynthesis of dTDP-rhamnose have been identified. These genes show strong homology to the rfb genes encoding dTDP-rhamnose biosynthesis in Salmonella enterica serova...

journal_title：Molecular microbiology

authors： Macpherson DF,Manning PA,Morona R

更新日期：1994-01-01 00:00:00

abstract：:Polymorphonuclear neutrophils are the most important mammalian host defence cells against infections with Pseudomonas aeruginosa. Screening of a signature tagged mutagenesis library of the non-piliated P. aeruginosa strain TBCF10839 uncovered that transposon inactivation of its pilY1 gene rendered the bacterium more r...

journal_title：Molecular microbiology

authors： Bohn YS,Brandes G,Rakhimova E,Horatzek S,Salunkhe P,Munder A,van Barneveld A,Jordan D,Bredenbruch F,Häussler S,Riedel K,Eberl L,Jensen PØ,Bjarnsholt T,Moser C,Hoiby N,Tümmler B,Wiehlmann L

更新日期：2009-02-01 00:00:00