Abstract:
:Lipochitin Nod signals are produced by rhizobia and are required for the establishment of a nitrogen-fixing symbiosis with a legume host. The nodulation genes encode products required for the synthesis of this signal and are induced in response to plant-produced flavonoid compounds. The addition of chitin and lipo-chitin oligomers to Bradyrhizobium japonicum cultures resulted in a significant reduction in the expression of a nod-lacZ fusion. Intracellular expression of NodC, encoding a chitin synthase, also reduced nod gene expression. In contrast, expression of the ChiB chitinase increased nod gene expression. The chain length of the oligosaccharide was important in feedback regulation, with chitotetraose molecules the best modulators of nod gene expression. Feedback regulation is mediated by the induction of nolA by chitin, resulting in elevated levels of the repressor protein, NodD2.
journal_name
Mol Microbioljournal_title
Molecular microbiologyauthors
Loh JT,Stacey Gdoi
10.1046/j.1365-2958.2001.02603.xsubject
Has Abstractpub_date
2001-09-01 00:00:00pages
1357-64issue
6eissn
0950-382Xissn
1365-2958pii
2603journal_volume
41pub_type
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