Abstract:
OBJECTIVES:To evaluate the acceptance of a multinutrient liquid nutrition supplement in psycho-geriatric nursing home patients and the effect on weight, plasma nutrients and activities of daily life. DESIGN:Double-blind, placebo-controlled 12-week intervention study. SETTING:Two nursing homes in Boxtel, The Netherlands. SUBJECTS:Forty-two (body mass index (BMI) <23 kg/m2 for men or <25 kg/m2 for women) psycho-geriatric nursing home patients aged 60 y or over. INTERVENTIONS:Provision with a complete micronutrient-enriched liquid nutrition supplement of 125 ml and 0.6 MJ (135 kcal) or placebo twice daily during daytime between main meals. Study parameters were assessed at 0, 6 and 12 weeks. MAIN OUTCOME FOR MEASURES: Weight, Barthel index of daily activities, several plasma values (albumin, C-reactive protein (CRP), homocysteine, thiamine, thiamine diphosphate (TDF), vitamin B6, vitamin B12, folic acid, vitamin D), bowel function. RESULTS:The supplement was well accepted. Thirty-five patients completed the intervention period (16 control group; 19 supplement group). Baseline daily nutrient intake was low. A statistically significant improvement was observed for body weight (difference between groups 2.2 kg, P=0.03), and homocysteine, vitamin B1, TDF, vitamin B6, vitamin B12, folate and vitamin D in the supplement group compared to the placebo group. No significant difference was observed in the Barthel index (mean difference -0.3+/-1.1 for both groups). No difference in occurrence of diarrhoea was observed. CONCLUSIONS:The study shows that nutritional supplementation is well accepted and can improve the nutritional status of psycho-geriatric nursing home patients. SPONSORSHIP:Numico Research BV.
journal_name
Eur J Clin Nutrjournal_title
European journal of clinical nutritionauthors
Wouters-Wesseling W,Wouters AE,Kleijer CN,Bindels JG,de Groot CP,van Staveren WAdoi
10.1038/sj.ejcn.1601319subject
Has Abstractpub_date
2002-03-01 00:00:00pages
245-51issue
3eissn
0954-3007issn
1476-5640journal_volume
56pub_type
临床试验,杂志文章,随机对照试验abstract::Sodium intake is assessed using 24 h urinary excretion; it is important to ensure urine collections are complete. This can be validated by monitoring urinary excretion of p-aminobenzoic acid (PABA) administered in tablet form at intervals during the urine collection. Unavoidable change of PABA tablet supplier and anal...
journal_title:European journal of clinical nutrition
pub_type: 杂志文章
doi:10.1038/s41430-018-0195-x
更新日期:2018-08-01 00:00:00
abstract:BACKGROUND/OBJECTIVES:The aim of this study was to evaluate the association of serum 25-hydroxyvitamin D (25(OH)D) with disability and frequency of relapses in relapsing-remitting multiple sclerosis (MS) patients. SUBJECTS/METHODS:The study included 184 patients with relapsing-remitting MS who were receiving immune-mo...
journal_title:European journal of clinical nutrition
pub_type: 杂志文章
doi:10.1038/ejcn.2016.51
更新日期:2016-09-01 00:00:00
abstract:OBJECTIVE:The purpose of the present study was to compare the nutrient intake and the nutritional status between German middle-class alcohol consumers and non-drinkers. DESIGN:Cross-sectional study using patients with different stages of alcoholic liver disease (ALD) and healthy volunteers. SETTING:Southern Germany. ...
journal_title:European journal of clinical nutrition
pub_type: 杂志文章
doi:10.1038/sj.ejcn.1601557
更新日期:2003-03-01 00:00:00
abstract:OBJECTIVE:The hypothesis was tested that the rate of postmenopausal bone loss is inversely associated with long-term urinary excretion of phyto-oestrogens, as a marker of habitual dietary intake. DESIGN:Secondary analysis of a 10-year follow-up study (1979 1989) among postmenopausal women in the Netherlands. SUBJECTS...
journal_title:European journal of clinical nutrition
pub_type: 杂志文章
doi:10.1038/sj.ejcn.1600659
更新日期:1998-11-01 00:00:00
abstract:OBJECTIVE:To study the effect of Lactobacillus helveticus fermented milk on sleep and health perception in elderly healthy subjects. SUBJECTS:The study included 29 healthy elderly subjects aged 60-81 years. METHODS:Prospective, randomized, double-blind and placebo-controlled, with a crossover design. The study includ...
journal_title:European journal of clinical nutrition
pub_type: 杂志文章,随机对照试验
doi:10.1038/sj.ejcn.1602898
更新日期:2009-01-01 00:00:00
abstract::Bias in diet reporting may be both random and non-random, and may be found with simpler as well as more advanced dietary instruments. A random bias will contribute to obscure relations between diet and disease. A systematic bias may obscure or aggravate such associations. Underreporting of non-protein energy has been ...
journal_title:European journal of clinical nutrition
pub_type: 杂志文章
doi:10.1038/sj.ejcn.1602589
更新日期:2007-07-01 00:00:00
abstract:OBJECTIVE:To measure the intake of selenium (Se) and the contribution of different food groups to Se intake in adults aged 18-64 y in Ireland. The adequacy of Se intake in the population is also assessed. DESIGN:Food consumption was estimated using a 7 day food diary for a representative sample (n=1379; men=662, women...
journal_title:European journal of clinical nutrition
pub_type: 杂志文章
doi:10.1038/sj.ejcn.1601323
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abstract:BACKGROUND/OBJECTIVE:To study whether a free supply of vitamin D(2) drops to 6-week-old infants together with tailor-made information handouts improves the vitamin D status after 7 weeks in the intervention group compared to a control group. SUBJECTS/METHODS:In this cluster randomized controlled trial in eight child h...
journal_title:European journal of clinical nutrition
pub_type: 杂志文章,随机对照试验
doi:10.1038/sj.ejcn.1602982
更新日期:2009-04-01 00:00:00
abstract:BACKGROUND/OBJECTIVES:To assess dietary patterns (DPs) in European adolescents and to examine their relationship with several indicators of sedentary behaviour. SUBJECTS/METHODS:A multinational cross-sectional study was carried out in 2202 adolescents (45.4% boys) aged 12.5-17.5 years. A self-reported questionnaire wi...
journal_title:European journal of clinical nutrition
pub_type: 杂志文章
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abstract:BACKGROUND/OBJECTIVES:It is not known if diets lower in greenhouse gas (GHG) emissions are also healthier. We evaluated the population health implications of changing to more sustainable diets in the UK, France, Finland, Italy and Sweden. SUBJECTS/METHODS:We developed a life table model to simulate mortality and morbi...
journal_title:European journal of clinical nutrition
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abstract:OBJECTIVES:To determine the nature of the relationship between mid-upper arm circumference (MUAC) and maximum voluntary contraction (MVC) in pre- and post-harvest seasons among adult Ethiopian farmers. SUBJECTS/METHODS:A total of 491 healthy adult men aged 18-60 years were recruited at pre-harvest season and followed ...
journal_title:European journal of clinical nutrition
pub_type: 杂志文章
doi:10.1038/sj.ejcn.1602966
更新日期:2009-04-01 00:00:00
abstract:OBJECTIVE:To determine whether dual-energy X-ray absorptiometry (DXA) is a valid method for body composition assessment of obese and non-obese subjects. DESIGN:Cross-sectional study. SUBJECTS:Chinese women living in Hong Kong; 66 of 91 subjects had body mass index (BMI) of >25 kg/m2. MEASUREMENTS:Anthropometrics, in...
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doi:10.1038/sj.ejcn.1600875
更新日期:1999-12-01 00:00:00
abstract:BACKGROUND/OBJECTIVES:Fall accidents may reduce an individual's quality of life and ability to perform the activities of daily life, and may delay recovery from illness. Consequently, medical institutions need to take measures to prevent falls. There are various risk factors for falls, including advanced age, illness a...
journal_title:European journal of clinical nutrition
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更新日期:2015-02-01 00:00:00
abstract:BACKGROUND/OBJECTIVES:Prediction equations are commonly used to estimate body fat from anthropometric measurements, but are population specific. We aimed to establish and validate a body composition prediction formula for Asian newborns, and compared the performance of this formula with that of a published equation. S...
journal_title:European journal of clinical nutrition
pub_type: 杂志文章
doi:10.1038/ejcn.2013.69
更新日期:2013-09-01 00:00:00
abstract:BACKGROUND:The ability to communicate food benefits is essential for the successful development of functional foods and their role in improving public health. However, the functional efficacy of foods often cannot be represented by food composition. The concept of virtual food components (VFCs)-food data that express h...
journal_title:European journal of clinical nutrition
pub_type: 杂志文章
doi:10.1038/sj.ejcn.1601769
更新日期:2004-02-01 00:00:00
abstract::Attempts to reduce glycaemia to bread were evaluated in healthy subjects. The contents of in vitro resistant starch (RS) were also measured in the bread products. The potential of including intact barley kernels at different concentrations (80% and 40%) was tested in two products (SCB-80 and SCB-40). Three variants of...
journal_title:European journal of clinical nutrition
pub_type: 杂志文章
doi:
更新日期:1994-03-01 00:00:00
abstract:OBJECTIVE:To study the variation in selenoprotein P levels in serum among healthy subjects from 17 European regions representing nine countries. SUBJECTS:Survey of 414 37-70-year-old subjects (197/217 males/females) from 17 regions. RESULTS:The level of selenoprotein P varied significantly among regions and countries...
journal_title:European journal of clinical nutrition
pub_type: 杂志文章
doi:
更新日期:1995-01-01 00:00:00
abstract:OBJECTIVE:To describe the influence of maternal weight and weight gain, placental volume and the rate of placental growth in early pregnancy on fetal dimensions measured sonographically. DESIGN:In a prospective study, 712 women were recruited from the antenatal clinic of the University Hospital of the West Indies. Dat...
journal_title:European journal of clinical nutrition
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journal_title:European journal of clinical nutrition
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journal_title:European journal of clinical nutrition
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doi:
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更新日期:2016-04-01 00:00:00
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journal_title:European journal of clinical nutrition
pub_type: 杂志文章
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更新日期:1990-05-01 00:00:00
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journal_title:European journal of clinical nutrition
pub_type: 杂志文章,meta分析
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更新日期:2012-03-01 00:00:00
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journal_title:European journal of clinical nutrition
pub_type: 杂志文章
doi:
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journal_title:European journal of clinical nutrition
pub_type: 杂志文章,随机对照试验
doi:10.1038/sj.ejcn.1602654
更新日期:2007-12-01 00:00:00
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journal_title:European journal of clinical nutrition
pub_type: 杂志文章
doi:10.1038/ejcn.2013.297
更新日期:2014-03-01 00:00:00
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journal_title:European journal of clinical nutrition
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更新日期:2004-03-01 00:00:00
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journal_title:European journal of clinical nutrition
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更新日期:2014-04-01 00:00:00
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journal_title:European journal of clinical nutrition
pub_type: 杂志文章
doi:10.1038/s41430-018-0212-0
更新日期:2019-03-01 00:00:00
abstract::A food frequency questionnaire (FFQ) was designed and validated for use in an epidemiological survey measuring coronary heart disease risk factors in British children. The questionnaire asked about the frequency of children's consumption of 35 food items over the previous month and was completed by parents/guardians. ...
journal_title:European journal of clinical nutrition
pub_type: 杂志文章
doi:
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